Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
PPFIA2	0	genome.wustl.edu	37	12	81777917	81777917	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	12	81777917	81777917	C	A	SNP	PPFIA2	ENST00000549396	human	ensembl	74_37	-1	known	missense	c.869	p.R290L	1.000	NULL	pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_SAM,pfscan_SAM	-	no_errors	PPFIA2	HGNC	ENSG00000139220	tier1	-	-	51	0	0.00	21	10	32.26	149	1	0.66	36	18	33.33
CKAP2	0	genome.wustl.edu	37	13	53048039	53048039	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	13	53048039	53048039	T	C	SNP	CKAP2	ENST00000378037	human	ensembl	74_37	+1	known	missense	c.1625	p.V542A	0.000	NULL	NULL	-	no_errors	CKAP2	HGNC	ENSG00000136108	tier1	-	-	113	0	0.00	54	17	23.94	220	0	0.00	96	33	25.58
NUF2	0	genome.wustl.edu	37	1	163313591	163313591	+	Missense_Mutation	SNP	T	T	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	163313591	163313591	T	G	SNP	NUF2	ENST00000271452	human	ensembl	74_37	+1	known	missense	c.738	p.D246E	0.980	NULL	pfam_Kinetochore_Nuf2	-	no_errors	NUF2	HGNC	ENSG00000143228	tier1	-	-	281	0	0.00	129	13	9.15	207	0	0.00	70	9	11.39
UBE2J1	0	genome.wustl.edu	37	6	90045027	90045027	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	6	90045027	90045027	G	T	SNP	UBE2J1	ENST00000435041	human	ensembl	74_37	-1	known	missense	c.552	p.S184R	1.000	NULL	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	-	no_errors	UBE2J1	HGNC	ENSG00000198833	tier1	-	-	53	0	0.00	37	10	20.83	197	1	0.51	121	27	18.24
OR2V2	0	genome.wustl.edu	37	5	180582647	180582647	+	Nonsense_Mutation	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	5	180582647	180582647	G	A	SNP	OR2V2	ENST00000328275	human	ensembl	74_37	+1	known	nonsense	c.705	p.W235*	0.005	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2V2	HGNC	ENSG00000182613	tier1	-	-	73	0	0.00	19	16	45.71	105	0	0.00	31	12	27.91
IF1	0	genome.wustl.edu	37	9	21440957	21440957	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	9	21440957	21440957	A	T	SNP	IF1	ENST00000276927	human	ensembl	74_37	+1	known	missense	c.451	p.T151S	0.000	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	-	no_errors	IF1	HGNC	ENSG00000197919	tier1	-	-	42	0	0.00	17	13	43.33	28	0	0.00	13	6	31.58
HOOK1	0	genome.wustl.edu	37	1	60330673	60330673	+	R	SNP	T	T	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	60330673	60330673	T	A	SNP	HOOK1	ENST00000466803	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	HOOK1	HGNC	ENSG00000134709	tier1	-	-	22	0	0.00	12	7	36.84	243	0	0.00	48	54	52.94
APOB	0	genome.wustl.edu	37	2	21247913	21247913	+	Nonsense_Mutation	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	2	21247913	21247913	G	T	SNP	APOB	ENST00000233242	human	ensembl	74_37	-1	known	nonsense	c.2328	p.Y776*	1.000	pfam_Vitellinogen_open_b-sht,superfamily_Lipid_transp_b-sht_shell	pfam_Lipid_transpt_N,pfam_Vitellinogen_open_b-sht,pfam_ApoB100_C,pfam_Lipid_transpt_open_b-sht,superfamily_Lipid_transp_b-sht_shell,superfamily_Vitellinogen_superhlx,superfamily_ARM-type_fold,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	APOB	HGNC	ENSG00000084674	tier1	-	-	84	0	0.00	47	23	32.86	216	0	0.00	102	41	28.47
LGALS7B	0	genome.wustl.edu	37	19	39281369	39281369	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	19	39281369	39281369	G	A	SNP	LGALS7B	ENST00000314980	human	ensembl	74_37	+1	known	missense	c.136	p.D46N	0.022	pfam_Galectin_CRD,superfamily_ConA-like_lec_gl_sf,smart_Galectin_CRD	pfam_Galectin_CRD,superfamily_ConA-like_lec_gl_sf,smart_Galectin_CRD	-	no_errors	LGALS7B	HGNC	ENSG00000178934	tier1	-	-	265	0	0.00	192	24	11.11	67	0	0.00	69	10	12.66
FRMD4B	0	genome.wustl.edu	37	3	69230187	69230187	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	3	69230187	69230187	C	A	SNP	FRMD4B	ENST00000398540	human	ensembl	74_37	-1	known	missense	c.2714	p.R905L	1.000	NULL	pfam_DUF3338,pfam_FERM_central,pfam_FERM_PH-like_C,pfam_FERM_N,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam	-	no_errors	FRMD4B	HGNC	ENSG00000114541	tier1	-	-	40	0	0.00	29	14	32.56	55	0	0.00	33	12	26.67
NRG3	0	genome.wustl.edu	37	10	84745311	84745311	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	10	84745311	84745311	C	A	SNP	NRG3	ENST00000404547	human	ensembl	74_37	+1	known	missense	c.2113	p.Q705K	1.000	NULL	pfscan_EG-like_dom	-	no_errors	NRG3	HGNC	ENSG00000185737	tier1	-	-	63	0	0.00	20	15	42.86	225	0	0.00	61	43	41.35
PLCL1	0	genome.wustl.edu	37	2	198948489	198948489	+	Nonsense_Mutation	SNP	C	C	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	2	198948489	198948489	C	G	SNP	PLCL1	ENST00000428675	human	ensembl	74_37	+1	known	nonsense	c.248	p.S83*	1.000	NULL	pfam_PLipase_C_PInositol-sp_X_dom,pfam_PLipase_C_Pinositol-sp_Y,pfam_PLipase_C_EF-hand-like,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_C2_dom,smart_Pleckstrin_homology,smart_PLipase_C_PInositol-sp_X_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,pfscan_C2_dom,pfscan_Pleckstrin_homology,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y,prints_Pinositol_PLipase_C	-	no_errors	PLCL1	HGNC	ENSG00000115896	tier1	-	-	63	0	0.00	23	6	20.69	214	0	0.00	67	32	32.00
FASN	0	genome.wustl.edu	37	17	80042811	80042811	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	17	80042811	80042811	G	C	SNP	FASN	ENST00000306749	human	ensembl	74_37	-1	known	missense	c.4428	p.N1476K	1.000	NULL	pfam_Acyl_transferase,pfam_Ketoacyl_synth_N,pfam_Thioesterase,pfam_PKS_KR,pfam_DH_sc/Rdtase_SDR,pfam_Ketoacyl_synth_C,pfam_ADH_C,pfam_Acyl_carrier_prot-like,pfam_Methyltransf_12,pfam_Methyltransf_11,superfamily_Thiolase-like,superfamily_Acyl_Trfase/lysoPLipase,superfamily_GroES-like,superfamily_Acyl_carrier_prot-like,superfamily_Malonyl_transacylase_ACP-bd,smart_PKS_Beta-ketoAc_synthase_dom,smart_PKS_acyl_transferase,smart_PKS_dehydratase,smart_PKS_ER,smart_PKS/FAS_KR,smart_PKS_PP-bd,pfscan_Acyl_carrier_prot-like	-	no_errors	FASN	HGNC	ENSG00000169710	tier1	-	-	71	0	0.00	90	18	16.67	14	0	0.00	10	5	33.33
SCNN1G	0	genome.wustl.edu	37	16	23197815	23197815	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	16	23197815	23197815	G	A	SNP	SCNN1G	ENST00000300061	human	ensembl	74_37	+1	known	missense	c.223	p.V75I	0.713	pfam_Na+channel_ASC,tigrfam_EnaC	pfam_Na+channel_ASC,prints_Na+channel_ASC,tigrfam_EnaC	-	no_errors	SCNN1G	HGNC	ENSG00000166828	tier1	-	-	29	0	0.00	6	3	33.33	107	0	0.00	19	16	45.71
SNX29	0	genome.wustl.edu	37	16	12497352	12497352	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	16	12497352	12497352	G	A	SNP	SNX29	ENST00000306030	human	ensembl	74_37	+1	known	missense	c.848	p.R283Q	1.000	superfamily_Phox,smart_Phox,pfscan_Phox	pfam_Phox,superfamily_Phox,smart_Phox,pfscan_Phox	-	no_errors	SNX29	HGNC	ENSG00000048471	tier1	-	-	78	0	0.00	36	8	18.18	204	0	0.00	90	33	26.83
CDCP2	0	genome.wustl.edu	37	1	54610408	54610408	+	Missense_Mutation	SNP	T	T	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	54610408	54610408	T	G	SNP	CDCP2	ENST00000371330	human	ensembl	74_37	-1	novel	missense	c.158	p.N53T	1.000	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	-	no_errors	CDCP2	HGNC	ENSG00000157211	tier1	-	-	68	0	0.00	38	14	26.92	165	0	0.00	102	32	23.88
ZFP37	0	genome.wustl.edu	37	9	115806243	115806243	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	9	115806243	115806243	T	C	SNP	ZFP37	ENST00000553380	human	ensembl	74_37	-1	known	missense	c.700	p.T234A	0.150	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZFP37	HGNC	ENSG00000136866	tier1	-	-	37	0	0.00	12	8	40.00	213	0	0.00	68	48	41.38
CD300LG	0	genome.wustl.edu	37	17	41930355	41930355	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	17	41930355	41930355	C	A	SNP	CD300LG	ENST00000317310	human	ensembl	74_37	+1	known	missense	c.455	p.A152D	0.029	NULL	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	CD300LG	HGNC	ENSG00000161649	tier1	-	-	70	0	0.00	39	23	37.10	129	0	0.00	68	34	33.33
TERT	0	genome.wustl.edu	37	5	1293552	1293552	+	Silent	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	5	1293552	1293552	G	A	SNP	TERT	ENST00000310581	human	ensembl	74_37	-1	known	silent	c.1449	p.N483	0.984	pfam_Telomerase_RBD,smart_Telomerase_RBD	pfam_Telomerase_RBD,pfam_RVT,smart_Telomerase_RBD,pfscan_RVT,prints_Telomerase_RT	-	no_errors	TERT	HGNC	ENSG00000164362	tier1	-	-	29	0	0.00	33	15	31.25	62	0	0.00	50	32	39.02
CDH6	0	genome.wustl.edu	37	5	31317976	31317976	+	Silent	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	5	31317976	31317976	G	T	SNP	CDH6	ENST00000265071	human	ensembl	74_37	+1	known	silent	c.1827	p.T609	0.996	pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH6	HGNC	ENSG00000113361	tier1	-	-	48	0	0.00	39	5	11.11	136	0	0.00	85	17	16.50
USH2A	0	genome.wustl.edu	37	1	216062047	216062047	+	Silent	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	216062047	216062047	G	T	SNP	USH2A	ENST00000366943	human	ensembl	74_37	-1	known	silent	c.7944	p.T2648	0.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_EGF_laminin,pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_LamG-like,smart_Laminin_N,smart_EGF_laminin,smart_Fibronectin_type3,smart_Laminin_G,pfscan_EGF_laminin,pfscan_Fibronectin_type3,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	USH2A	HGNC	ENSG00000042781	tier1	-	-	40	0	0.00	16	6	27.27	197	0	0.00	53	41	43.62
SYT9	0	genome.wustl.edu	37	11	7334914	7334914	+	Silent	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	11	7334914	7334914	C	A	SNP	SYT9	ENST00000318881	human	ensembl	74_37	+1	known	silent	c.786	p.I262	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom,prints_C2_dom	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom,prints_Synaptotagmin,prints_C2_dom	-	no_errors	SYT9	HGNC	ENSG00000170743	tier1	-	-	48	0	0.00	27	11	28.95	225	0	0.00	103	24	18.90
MAN2A2	0	genome.wustl.edu	37	15	91456916	91456916	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	15	91456916	91456916	A	G	SNP	MAN2A2	ENST00000360468	human	ensembl	74_37	+1	known	missense	c.2791	p.I931V	1.000	pfam_Glyco_hydro_38_C,superfamily_Gal_mutarotase_SF_dom	pfam_Glyco_hydro_38_N,pfam_Glyco_hydro_38_C,pfam_Glyco_hydro_38_cen_dom,superfamily_Gal_mutarotase_SF_dom,superfamily_Glyco_hydro/deAcase_b/a-brl,smart_Glyco_hydro_38_cen_dom	-	no_errors	MAN2A2	HGNC	ENSG00000196547	tier1	-	-	27	0	0.00	23	4	14.81	107	0	0.00	78	18	18.75
SCAND3	0	genome.wustl.edu	37	6	28554200	28554200	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	6	28554200	28554200	G	T	SNP	SCAND3	ENST00000452236	human	ensembl	74_37	-1	known	missense	c.295	p.Q99K	1.000	pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,pfscan_Tscrpt_reg_SCAN	pfam_Tscrpt_reg_SCAN,pfam_Integrase_cat-core,pfam_HATC_dom_C,superfamily_Retrov_capsid_C,superfamily_RNaseH-like_dom,smart_Tscrpt_reg_SCAN,pfscan_Integrase_cat-core,pfscan_Tscrpt_reg_SCAN	-	no_errors	SCAND3	HGNC	ENSG00000232040	tier1	-	-	67	0	0.00	56	9	13.85	82	0	0.00	54	29	34.94
PLEKHA2	0	genome.wustl.edu	37	8	38793524	38793524	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	8	38793524	38793524	G	C	SNP	PLEKHA2	ENST00000420274	human	ensembl	74_37	+1	known	missense	c.154	p.G52R	0.986	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	PLEKHA2	HGNC	ENSG00000169499	tier1	-	-	86	0	0.00	5	14	73.68	181	0	0.00	26	62	69.66
CDH12	0	genome.wustl.edu	37	5	21751881	21751881	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	5	21751881	21751881	C	T	SNP	CDH12	ENST00000382254	human	ensembl	74_37	-1	known	missense	c.2350	p.E784K	0.998	pfam_Cadherin_cytoplasmic-dom	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH12	HGNC	ENSG00000154162	tier1	-	-	49	0	0.00	12	36	75.00	149	0	0.00	49	105	67.74
MYO1H	0	genome.wustl.edu	37	12	109845713	109845713	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	12	109845713	109845713	A	G	SNP	MYO1H	ENST00000431443	human	ensembl	74_37	+1	known	missense	c.1102	p.N368D	1.000	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS	-	no_errors	MYO1H	HGNC	ENSG00000174527	tier1	-	-	119	0	0.00	49	23	31.94	262	0	0.00	116	56	32.56
ACSM4	0	genome.wustl.edu	37	12	7480905	7480905	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	12	7480905	7480905	C	A	SNP	ACSM4	ENST00000399422	human	ensembl	74_37	+1	novel	missense	c.1679	p.P560Q	1.000	NULL	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSM4	HGNC	ENSG00000215009	tier1	-	-	84	0	0.00	43	16	27.12	304	0	0.00	187	46	19.74
YTHDC2	0	genome.wustl.edu	37	5	112871433	112871433	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	5	112871433	112871433	C	A	SNP	YTHDC2	ENST00000161863	human	ensembl	74_37	+1	known	missense	c.1040	p.S347Y	1.000	pfam_D/R_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_YTH_domain,pfam_Helicase-assoc_dom,pfam_Helicase_C,pfam_D/R_helicase_DEAD/DEAH_N,pfam_DUF1605,pfam_R3H_ss-bd,superfamily_P-loop_NTPase,superfamily_Ankyrin_rpt-contain_dom,smart_R3H_ss-bd,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Helicase-assoc_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_R3H_ss-bd,pfscan_YTH_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	YTHDC2	HGNC	ENSG00000047188	tier1	-	-	81	0	0.00	32	17	34.69	230	0	0.00	93	29	23.77
GCOM1	0	genome.wustl.edu	37	15	57918073	57918073	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	15	57918073	57918073	G	C	SNP	GCOM1	ENST00000380569	human	ensembl	74_37	+1	known	missense	c.508	p.D170H	0.994	NULL	NULL	-	no_errors	GCOM1	HGNC	ENSG00000137878	tier1	-	-	33	0	0.00	7	3	30.00	175	0	0.00	44	36	45.00
TP53	0	genome.wustl.edu	37	17	7577136	7577136	+	Missense_Mutation	SNP	T	T	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	17	7577136	7577136	T	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.802	p.N268Y	0.001	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	27	0	0.00	2	18	90.00	189	1	0.53	26	85	75.89
COL6A6	0	genome.wustl.edu	37	3	130282278	130282278	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	3	130282278	130282278	A	T	SNP	COL6A6	ENST00000358511	human	ensembl	74_37	+1	known	missense	c.431	p.E144V	0.895	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_VWF_A,pfam_Collagen,smart_VWF_A,pfscan_VWF_A	-	no_errors	COL6A6	HGNC	ENSG00000206384	tier1	-	-	57	0	0.00	35	7	16.67	82	0	0.00	40	15	27.27
KC6	0	genome.wustl.edu	37	12	4919890	4919890	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	12	4919890	4919890	A	T	SNP	KC6	ENST00000280684	human	ensembl	74_37	+1	known	missense	c.683	p.E228V	0.070	prints_K_chnl_volt-dep_Kv1.6	pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv1.6,prints_K_chnl_volt-dep_Kv1,prints_K_chnl_volt-dep_Kv	-	no_errors	KC6	HGNC	ENSG00000151079	tier1	-	-	67	0	0.00	52	9	14.75	162	0	0.00	100	31	23.66
TMEM200A	0	genome.wustl.edu	37	6	130762280	130762280	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	6	130762280	130762280	G	C	SNP	TMEM200A	ENST00000296978	human	ensembl	74_37	+1	known	missense	c.713	p.S238T	0.372	NULL	pfam_DUF2371_TMEM200	-	no_errors	TMEM200A	HGNC	ENSG00000164484	tier1	-	-	39	0	0.00	16	5	23.81	152	0	0.00	81	15	15.62
ASPDH	0	genome.wustl.edu	37	19	51015485	51015485	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	19	51015485	51015485	C	T	SNP	ASPDH	ENST00000389208	human	ensembl	74_37	-1	known	missense	c.716	p.S239N	0.613	pfam_Asp_DH	pfam_Asp_DH,pfam_Asp/hSer_DH_D-bd	-	no_errors	ASPDH	HGNC	ENSG00000204653	tier1	-	-	54	0	0.00	30	6	16.67	29	0	0.00	17	11	39.29
KIAA1468	0	genome.wustl.edu	37	18	59947038	59947038	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	18	59947038	59947038	T	C	SNP	KIAA1468	ENST00000256858	human	ensembl	74_37	+1	known	missense	c.3101	p.V1034A	1.000	superfamily_ARM-type_fold	pfam_HEAT,superfamily_ARM-type_fold,smart_LisH_dimerisation,pfscan_HEAT_type_2,pfscan_LisH_dimerisation	-	no_errors	KIAA1468	HGNC	ENSG00000134444	tier1	-	-	70	0	0.00	29	16	35.56	207	0	0.00	82	30	26.55
TP53	0	genome.wustl.edu	37	17	7577137	7577137	+	Silent	SNP	C	C	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	17	7577137	7577137	C	T	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	silent	c.801	p.R267	0.001	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	27	0	0.00	2	18	90.00	190	0	0.00	26	85	76.58
MAPK6	0	genome.wustl.edu	37	15	52338058	52338058	+	R	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	15	52338058	52338058	G	C	SNP	MAPK6	ENST00000558063	human	ensembl	74_37	+1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	MAPK6	HGNC	ENSG00000069956	tier1	-	-	80	0	0.00	24	9	27.27	84	0	0.00	30	14	31.82
NBPF22P	0	genome.wustl.edu	37	5	85578685	85578685	+	R	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	5	85578685	85578685	G	C	SNP	NBPF22P	ENST00000590707	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	NBPF22P	HGNC	ENSG00000205449	tier1	-	-	156	0	0.00	87	26	23.01	79	0	0.00	42	14	25.00
GBP7	0	genome.wustl.edu	37	1	89618012	89618012	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	89618012	89618012	C	A	SNP	GBP7	ENST00000294671	human	ensembl	74_37	-1	known	missense	c.564	p.K188N	0.981	pfam_Guanylate-bd_N,superfamily_P-loop_NTPase	pfam_Guanylate-bd_N,pfam_Guanylate-bd_C,superfamily_Guanylate-bd_C,superfamily_P-loop_NTPase	-	no_errors	GBP7	HGNC	ENSG00000213512	tier1	-	-	64	0	0.00	33	11	25.00	179	0	0.00	95	30	23.44
ARPP19	0	genome.wustl.edu	37	15	52844135	52844135	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	15	52844135	52844135	C	T	SNP	ARPP19	ENST00000249822	human	ensembl	74_37	-1	known	missense	c.335	p.G112D	1.000	NULL	pfam_Endosulphine	-	no_errors	ARPP19	HGNC	ENSG00000128989	tier1	-	-	56	0	0.00	18	8	30.77	64	0	0.00	16	17	51.52
CRISP3	0	genome.wustl.edu	37	6	49705150	49705150	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	6	49705150	49705150	A	T	SNP	CRISP3	ENST00000371159	human	ensembl	74_37	-1	novel	missense	c.53	p.F18Y	0.000	NULL	pfam_CAP_domain,pfam_Cysteine_rich_secretory,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1,prints_Allrgn_V5/Tpx1	-	no_errors	CRISP3	HGNC	ENSG00000096006	tier1	-	-	60	0	0.00	30	10	25.00	267	0	0.00	90	42	31.82
CP	0	genome.wustl.edu	37	3	148928119	148928119	+	Nonsense_Mutation	SNP	T	T	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	3	148928119	148928119	T	A	SNP	CP	ENST00000264613	human	ensembl	74_37	-1	known	nonsense	c.442	p.K148*	1.000	pfam_Cu-oxidase_3,superfamily_Cupredoxin	pfam_Cu-oxidase_2,pfam_Cu-oxidase_3,pfam_Cu-oxidase,superfamily_Cupredoxin	-	no_errors	CP	HGNC	ENSG00000047457	tier1	-	-	87	0	0.00	40	20	33.33	264	0	0.00	103	36	25.90
SFMBT2	0	genome.wustl.edu	37	10	7262457	7262457	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	10	7262457	7262457	C	A	SNP	SFMBT2	ENST00000361972	human	ensembl	74_37	-1	known	missense	c.1246	p.A416S	1.000	pfam_Mbt,smart_Mbt,pfscan_Mbt	pfam_Mbt,pfam_DUF3588,pfam_SAM_type1,pfam_Pointed_dom,superfamily_SAM/pointed,superfamily_ARM-type_fold,smart_Mbt,smart_SAM,pfscan_Mbt	-	no_errors	SFMBT2	HGNC	ENSG00000198879	tier1	-	-	94	0	0.00	86	13	13.13	177	0	0.00	145	32	18.08
FOXD3	0	genome.wustl.edu	37	1	63789443	63789443	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	63789443	63789443	G	C	SNP	FOXD3	ENST00000371116	human	ensembl	74_37	+1	known	missense	c.714	p.K238N	1.000	NULL	pfam_TF_fork_head,smart_TF_fork_head,prints_TF_fork_head,pfscan_TF_fork_head	-	no_errors	FOXD3	HGNC	ENSG00000187140	tier1	-	-	66	0	0.00	29	23	44.23	17	0	0.00	15	2	11.76
PPRC1	0	genome.wustl.edu	37	10	103901296	103901296	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	10	103901296	103901296	G	T	SNP	PPRC1	ENST00000278070	human	ensembl	74_37	+1	known	missense	c.3031	p.V1011F	0.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	PPRC1	HGNC	ENSG00000148840	tier1	-	-	37	0	0.00	16	15	48.39	157	0	0.00	58	34	36.96
ZNF521	0	genome.wustl.edu	37	18	22806657	22806657	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	18	22806657	22806657	A	T	SNP	ZNF521	ENST00000361524	human	ensembl	74_37	-1	known	missense	c.1225	p.Y409N	1.000	smart_Znf_C2H2-like	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF521	HGNC	ENSG00000198795	tier1	-	-	60	0	0.00	27	14	34.15	188	0	0.00	94	33	25.98
MGA	0	genome.wustl.edu	37	15	41989072	41989072	+	Missense_Mutation	SNP	C	C	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	15	41989072	41989072	C	G	SNP	MGA	ENST00000219905	human	ensembl	74_37	+1	known	missense	c.1864	p.L622V	0.983	NULL	pfam_TF_T-box,pfam_bHLH_dom,superfamily_p53-like_TF_D-bd,superfamily_bHLH_dom,smart_TF_T-box,smart_bHLH_dom,pfscan_bHLH_dom,pfscan_TF_T-box,prints_TF_T-box	-	no_errors	MGA	HGNC	ENSG00000174197	tier1	-	-	71	0	0.00	26	13	33.33	300	0	0.00	91	36	28.35
NOTCH3	0	genome.wustl.edu	37	19	15271540	15271540	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	19	15271540	15271540	A	T	SNP	NOTCH3	ENST00000263388	human	ensembl	74_37	-1	known	missense	c.6899	p.L2300H	0.024	pirsf_Notch	pirsf_Notch,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,pfam_Ankyrin_rpt,pfam_Notch_dom,pfam_Notch_NODP_dom,pfam_Notch_NOD_dom,pfam_EGF_extracell,pfam_DUF3454_notch,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,prints_Notch_3,prints_Notch_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom	-	no_errors	NOTCH3	HGNC	ENSG00000074181	tier1	-	-	76	0	0.00	40	12	23.08	56	0	0.00	24	7	22.58
KC6	0	genome.wustl.edu	37	12	4919850	4919850	+	Missense_Mutation	SNP	T	T	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	12	4919850	4919850	T	A	SNP	KC6	ENST00000280684	human	ensembl	74_37	+1	known	missense	c.643	p.S215T	0.000	NULL	pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv1.6,prints_K_chnl_volt-dep_Kv1,prints_K_chnl_volt-dep_Kv	-	no_errors	KC6	HGNC	ENSG00000151079	tier1	-	-	39	0	0.00	33	7	17.50	170	0	0.00	105	26	19.85
PCSK5	0	genome.wustl.edu	37	9	78710840	78710840	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	9	78710840	78710840	C	T	SNP	PCSK5	ENST00000545128	human	ensembl	74_37	+1	known	missense	c.929	p.A310V	1.000	pfam_Peptidase_S8/S53_dom,superfamily_Peptidase_S8/S53_dom	pfam_Peptidase_S8/S53_dom,pfam_PrprotnconvertsP,superfamily_Peptidase_S8/S53_dom,superfamily_Galactose-bd-like,superfamily_Growth_fac_rcpt_N_dom,superfamily_Prot_inh_propept,smart_Furin_repeat,smart_EG-like_dom,prints_Peptidase_S8_subtilisin-rel	-	no_errors	PCSK5	HGNC	ENSG00000099139	tier1	-	-	48	0	0.00	35	9	20.00	222	0	0.00	119	31	20.67
NUF2	0	genome.wustl.edu	37	1	163313586	163313586	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	163313586	163313586	G	A	SNP	NUF2	ENST00000271452	human	ensembl	74_37	+1	known	missense	c.733	p.V245M	1.000	NULL	pfam_Kinetochore_Nuf2	-	no_errors	NUF2	HGNC	ENSG00000143228	tier1	-	-	279	0	0.00	125	16	11.35	207	0	0.00	72	8	10.00
SCML2	0	genome.wustl.edu	37	X	18259309	18259309	+	R	SNP	T	T	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	X	18259309	18259309	T	C	SNP	SCML2	ENST00000491988	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.043	-	-	-	no_errors	SCML2	HGNC	ENSG00000102098	tier1	-	-	49	0	0.00	28	17	37.78	161	0	0.00	119	47	28.14
CDCA2	0	genome.wustl.edu	37	8	25337454	25337454	+	Silent	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	8	25337454	25337454	G	A	SNP	CDCA2	ENST00000330560	human	ensembl	74_37	+1	known	silent	c.846	p.V282	0.002	NULL	NULL	-	no_errors	CDCA2	HGNC	ENSG00000184661	tier1	-	-	57	0	0.00	13	11	45.83	148	0	0.00	28	29	50.88
UNKL	0	genome.wustl.edu	37	16	1464016	1464016	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	16	1464016	1464016	A	G	SNP	UNKL	ENST00000397462	human	ensembl	74_37	-1	known	missense	c.118	p.S40P	0.942	NULL	pfam_Znf_CCCH,smart_Znf_CCCH	-	no_errors	UNKL	HGNC	ENSG00000059145	tier1	rs202202852	GMAF=0.0005	61	0	0.00	14	14	50.00	66	0	0.00	23	16	41.03
SLURP1	0	genome.wustl.edu	37	8	143823300	143823300	+	Silent	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	8	143823300	143823300	G	T	SNP	SLURP1	ENST00000246515	human	ensembl	74_37	-1	known	silent	c.99	p.T33	0.000	pfam_LY6_UPAR	pfam_LY6_UPAR	-	no_errors	SLURP1	HGNC	ENSG00000126233	tier1	-	-	62	0	0.00	42	5	10.64	78	0	0.00	36	4	10.00
C12orf55	0	genome.wustl.edu	37	12	96883406	96883406	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	12	96883406	96883406	C	A	SNP	C12orf55	ENST00000524981	human	ensembl	74_37	+1	putative	missense	c.19	p.P7T	0.000	NULL	superfamily_Fibronectin_type3	-	no_errors	C12orf55	HGNC	ENSG00000188596	tier1	-	-	82	0	0.00	31	10	23.81	39	0	0.00	30	7	18.92
MYBPC2	0	genome.wustl.edu	37	19	50949209	50949209	+	Silent	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	19	50949209	50949209	G	A	SNP	MYBPC2	ENST00000357701	human	ensembl	74_37	+1	known	silent	c.1206	p.K402	1.000	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	MYBPC2	HGNC	ENSG00000086967	tier1	-	-	63	0	0.00	16	14	46.67	190	1	0.52	38	30	44.12
BFAR	0	genome.wustl.edu	37	16	14761590	14761590	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	16	14761590	14761590	A	G	SNP	BFAR	ENST00000261658	human	ensembl	74_37	+1	known	missense	c.1259	p.N420S	1.000	NULL	pfam_SAM_type1,pfam_Znf_C3HC4_RING-type,pfam_SAM_2,superfamily_SAM/pointed,smart_Znf_RING,smart_SAM,pfscan_SAM,pfscan_Znf_RING	-	no_errors	BFAR	HGNC	ENSG00000103429	tier1	-	-	76	0	0.00	29	17	36.96	233	1	0.43	119	42	26.09
STX7	0	genome.wustl.edu	37	6	132781974	132781974	+	Frame_Shift_Del	DEL	T	T	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	-	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	6	132781974	132781974	T	-	DEL	STX7	ENST00000367941	human	ensembl	74_37	-1	known	frame_shift_del	c.709	p.T237fs	1.000	NULL	pfam_T_SRE_dom,pfam_Syntaxin_N,superfamily_t-SRE,smart_Syntaxin_N,smart_T_SRE_dom,pfscan_T_SRE_dom	-	no_errors	STX7	HGNC	ENSG00000079950	tier1			43	0	0.00	21	6	22.22	131	0	0.00	54	12	18.18
TP53	0	genome.wustl.edu	37	17	7577134	7577134	+	Frame_Shift_Del	DEL	G	G	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	17	7577134	7577134	G	-	DEL	TP53	ENST00000269305	human	ensembl	74_37	-1	known	frame_shift_del	c.804	p.N268fs	0.425	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1			28	0	0.00	3	16	84.21	189	0	0.00	28	83	74.77
ZEB2	0	genome.wustl.edu	37	2	145157714	145157715	+	Frame_Shift_Del	DEL	TT	TT	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	TT	TT	TT	-	TT	TT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	2	145157714	145157715	TT	-	DEL	ZEB2	ENST00000303660	human	ensembl	74_37	-1	known	frame_shift_del	c.1040_1039	p.N347fs	1.000:1.000	NULL	superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	ZEB2	HGNC	ENSG00000169554	tier1			104	0	0.00	51	13	20.31	232	0	0.00	139	36	20.57
SLC8A3	0	genome.wustl.edu	37	14	70634157	70634157	+	Frame_Shift_Del	DEL	G	G	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	14	70634157	70634157	G	-	DEL	SLC8A3	ENST00000381269	human	ensembl	74_37	-1	known	frame_shift_del	c.983	p.P328fs	1.000	tigrfam_Na_Ca_Ex	pfam_NaCa_Exmemb,pfam_Calx_beta,smart_Calx_beta,prints_Na_Ca_Ex,tigrfam_Na_Ca_Ex	-	no_errors	SLC8A3	HGNC	ENSG00000100678	tier1			52	0	0.00	20	7	25.93	214	0	0.00	46	36	43.90
AKAP11	0	genome.wustl.edu	37	13	42875991	42875991	+	Frame_Shift_Del	DEL	A	A	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	13	42875991	42875991	A	-	DEL	AKAP11	ENST00000025301	human	ensembl	74_37	+1	known	frame_shift_del	c.3109	p.K1037fs	0.393	NULL	NULL	-	no_errors	AKAP11	HGNC	ENSG00000023516	tier1			75	0	0.00	55	14	20.29	229	0	0.00	147	39	20.97
SLC12A9	0	genome.wustl.edu	37	7	100459181	100459192	+	In_Frame_Del	DEL	TCAGCCAGGCCT	TCAGCCAGGCCT	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	TCAGCCAGGCCT	TCAGCCAGGCCT	TCAGCCAGGCCT	-	TCAGCCAGGCCT	TCAGCCAGGCCT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	7	100459181	100459192	TCAGCCAGGCCT	-	DEL	SLC12A9	ENST00000354161	human	ensembl	74_37	+1	known	in_frame_del	c.1511_1522	p.SQAL505in_frame_del	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.992:0.999	pfam_AA-permease/SLC12A_dom	pfam_AA-permease/SLC12A_dom	-	no_errors	SLC12A9	HGNC	ENSG00000146828	tier1			30	0	0.00	12	5	29.41	30	0	0.00	12	5	29.41
TSHZ2	0	genome.wustl.edu	37	20	51872532	51872539	+	Frame_Shift_Del	DEL	GTCCAACT	GTCCAACT	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	GTCCAACT	GTCCAACT	GTCCAACT	-	GTCCAACT	GTCCAACT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	20	51872532	51872539	GTCCAACT	-	DEL	TSHZ2	ENST00000371497	human	ensembl	74_37	+1	known	frame_shift_del	c.2535_2542	p.S846fs	1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000	superfamily_Homeodomain-like,smart_Homeobox_dom	superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	TSHZ2	HGNC	ENSG00000182463	tier1			197	0	0.00	114	14	10.94	197	0	0.00	114	14	10.94
SLC2A7	0	genome.wustl.edu	37	1	9070297	9070297	+	Frame_Shift_Del	DEL	G	G	-			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	9070297	9070297	G	-	DEL	SLC2A7	ENST00000400906	human	ensembl	74_37	-1	known	frame_shift_del	c.1021	p.V342fs	0.000	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Sugar/inositol_transpt	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,prints_Sugar/inositol_transpt,pfscan_MFS_dom,tigrfam_Sugar/inositol_transpt	-	no_errors	SLC2A7	HGNC	ENSG00000197241	tier1			76	0	0.00	82	21	20.39	31	0	0.00	36	4	10.00
ARHGEF4	0	genome.wustl.edu	37	2	131803760	131803760	+	Nonstop_Mutation	SNP	T	T	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	2	131803760	131803760	T	C	SNP	ARHGEF4	ENST00000326016	human	ensembl	74_37	+1	known	nonstop	c.2071	p.*691R	1.000	NULL	pfam_DH-domain,pfam_SH3_domain,pfam_SH3_2,pfam_Pleckstrin_homology,superfamily_DH-domain,superfamily_SH3_domain,smart_SH3_domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_DH-domain	-	no_errors	ARHGEF4	HGNC	ENSG00000136002	tier1	-	-	84	0	0.00	36	18	33.33	47	0	0.00	9	8	47.06
IGFN1	0	genome.wustl.edu	37	1	201190739	201190739	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	201190739	201190739	G	A	SNP	IGFN1	ENST00000335211	human	ensembl	74_37	+1	known	missense	c.10066	p.V3356M	0.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	IGFN1	HGNC	ENSG00000163395	tier1	-	-	52	0	0.00	8	30	76.92	50	0	0.00	4	22	84.62
SREBF1	0	genome.wustl.edu	37	17	17719281	17719281	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	17	17719281	17719281	G	T	SNP	SREBF1	ENST00000355815	human	ensembl	74_37	-1	known	missense	c.2366	p.A789D	1.000	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	SREBF1	HGNC	ENSG00000072310	tier1	-	-	59	0	0.00	25	10	28.57	26	0	0.00	8	5	38.46
CD84	0	genome.wustl.edu	37	1	160549203	160549203	+	Silent	SNP	A	A	G			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	160549203	160549203	A	G	SNP	CD84	ENST00000534968	human	ensembl	74_37	-1	known	silent	c.25	p.L9	0.999	NULL	pfscan_Ig-like_dom	-	no_errors	CD84	HGNC	ENSG00000066294	tier1	-	-	71	0	0.00	18	7	28.00	207	0	0.00	101	8	7.34
ACTR5	0	genome.wustl.edu	37	20	37380900	37380900	+	Missense_Mutation	SNP	G	G	C			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	20	37380900	37380900	G	C	SNP	ACTR5	ENST00000243903	human	ensembl	74_37	+1	known	missense	c.732	p.E244D	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related	-	no_errors	ACTR5	HGNC	ENSG00000101442	tier1	-	-	71	0	0.00	41	7	14.58	84	0	0.00	67	4	5.63
PAPOLG	0	genome.wustl.edu	37	2	60997608	60997608	+	Missense_Mutation	SNP	T	T	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	2	60997608	60997608	T	A	SNP	PAPOLG	ENST00000238714	human	ensembl	74_37	+1	known	missense	c.454	p.F152I	1.000	pfam_PolA_pol_cen_dom,pfam_Nucleotidyltransferase,pirsf_PolyA_polymerase	pfam_PolA_pol_cen_dom,pfam_PolA_pol_R-bd_dom,pfam_Nucleotidyltransferase,superfamily_NuclTrfase_I_C,pirsf_PolyA_polymerase	-	no_errors	PAPOLG	HGNC	ENSG00000115421	tier1	-	-	101	0	0.00	45	16	26.23	314	2	0.63	107	41	27.70
INPP5B	0	genome.wustl.edu	37	1	38411475	38411476	+	Frame_Shift_Ins	INS	-	-	A			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	1	38411475	38411476	-	A	INS	INPP5B	ENST00000373023	human	ensembl	74_37	-1	known	frame_shift_ins	c.105_104	p.L36fs	1.000:1.000	NULL	pfam_Endo/exonuclease/phosphatase,pfam_RhoGAP_dom,superfamily_Endo/exonuclease/phosphatase,superfamily_Rho_GTPase_activation_prot,smart_IPPc,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	INPP5B	HGNC	ENSG00000204084	tier1			49	0	0.00	16	2	11.11	21	0	0.00	4	0	0.00
BCR	0	genome.wustl.edu	37	22	23658274	23658275	+	R	INS	-	-	TTC			TCGA-X6-A8C2-01A-11D-A36J-09	TCGA-X6-A8C2-10A-01D-A36M-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	c9802b37-e213-4a7a-afcd-5822502fb968	18d5c618-c91c-4714-9683-ec3098cb28bd	22	23658274	23658275	-	TTC	INS	BCR	ENST00000436990	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	BCR	HGNC	ENSG00000186716	tier1			8	0	0.00	7	2	22.22	0	0	0.00	0	0	0.00