Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ZNF671	0	genome.wustl.edu	37	19	58232323	58232323	+	Missense_Mutation	SNP	A	A	T			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	19	58232323	58232323	A	T	SNP	ZNF671	ENST00000317398	human	ensembl	74_37	-1	known	missense	c.1131	p.F377L	0.026	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF671	HGNC	ENSG00000083814	tier1	-	-	35	0	0.00	16	8	33.33	69	0	0.00	60	20	25.00
MAP4K1	0	genome.wustl.edu	37	19	39088139	39088139	+	Missense_Mutation	SNP	G	G	A			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	19	39088139	39088139	G	A	SNP	MAP4K1	ENST00000591517	human	ensembl	74_37	-1	known	missense	c.1765	p.R589C	1.000	pfam_Citron,smart_Citron	pfam_Prot_kinase_dom,pfam_Citron,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Citron,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	MAP4K1	HGNC	ENSG00000104814	tier1	-	-	40	0	0.00	38	10	20.83	52	0	0.00	47	13	21.67
CCDC132	0	genome.wustl.edu	37	7	92938151	92938151	+	Nonsense_Mutation	SNP	C	C	T			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	7	92938151	92938151	C	T	SNP	CCDC132	ENST00000305866	human	ensembl	74_37	+1	known	nonsense	c.1645	p.Q549*	1.000	NULL	pfam_Vacuolar_sorting-assoc_54,pfam_DUF2451_C	-	no_errors	CCDC132	HGNC	ENSG00000004766	tier1	-	-	49	0	0.00	19	7	26.92	82	0	0.00	52	15	22.39
OR7D2	0	genome.wustl.edu	37	19	9297316	9297316	+	Missense_Mutation	SNP	C	C	G			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	19	9297316	9297316	C	G	SNP	OR7D2	ENST00000344248	human	ensembl	74_37	+1	known	missense	c.859	p.P287A	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR7D2	HGNC	ENSG00000188000	tier1	-	-	48	0	0.00	27	5	15.62	27	0	0.00	28	12	30.00
LRRC7	0	genome.wustl.edu	37	1	70477507	70477507	+	Missense_Mutation	SNP	T	T	G			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	1	70477507	70477507	T	G	SNP	LRRC7	ENST00000035383	human	ensembl	74_37	+1	known	missense	c.918	p.C306W	0.956	NULL	pfam_Leu-rich_rpt,pfam_PDZ,superfamily_PDZ,smart_Leu-rich_rpt_typical-subtyp,smart_PDZ,pfscan_PDZ	-	no_errors	LRRC7	HGNC	ENSG00000033122	tier1	-	-	61	0	0.00	31	11	26.19	76	0	0.00	51	12	19.05
ZDHHC6	0	genome.wustl.edu	37	10	114194138	114194138	+	Nonsense_Mutation	SNP	G	G	A			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	10	114194138	114194138	G	A	SNP	ZDHHC6	ENST00000369405	human	ensembl	74_37	-1	known	nonsense	c.820	p.Q274*	1.000	NULL	pfam_Znf_DHHC_palmitoyltrfase,pfam_SH3_2,superfamily_SH3_domain,pfscan_Znf_DHHC_palmitoyltrfase	-	no_errors	ZDHHC6	HGNC	ENSG00000023041	tier1	-	-	60	0	0.00	32	5	13.51	123	0	0.00	88	13	12.87
CD3EAP	0	genome.wustl.edu	37	19	45912297	45912297	+	Silent	SNP	G	G	A			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	19	45912297	45912297	G	A	SNP	CD3EAP	ENST00000589804	human	ensembl	74_37	+1	known	silent	c.1077	p.L359	0.006	NULL	pfam_D-dir_R_pol1_su_RPA34	-	no_errors	CD3EAP	HGNC	ENSG00000117877	tier1	-	-	92	0	0.00	65	7	9.72	57	0	0.00	45	4	8.16
FAM120A	0	genome.wustl.edu	37	9	96259883	96259884	+	Splice_Site	INS	-	-	A			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	9	96259883	96259884	-	A	INS	FAM120A	ENST00000333936	human	ensembl	74_37	+1	known	splice_site_ins	c.933+2_933+1	e4+2	1.000:0.997	-	-	-	no_errors	FAM120A	HGNC	ENSG00000048828	tier1			38	0	0.00	26	4	13.33	12	0	0.00	4	0	0.00
SPPL2B	0	genome.wustl.edu	37	19	2341094	2341101	+	R	DEL	CTCCCTGG	CTCCCTGG	-			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	CTCCCTGG	CTCCCTGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	19	2341094	2341101	CTCCCTGG	-	DEL	SPPL2B	ENST00000592738	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000:0.010:0.001:0.000:0.000:0.001:0.000	-	-	-	no_errors	SPPL2B	HGNC	ENSG00000005206	tier1			1	0	0.00	1	0	0.00	1	0	0.00	1	0	0.00
TRAPPC12	0	genome.wustl.edu	37	2	3391677	3391677	+	Nonsense_Mutation	SNP	G	G	T			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	2	3391677	3391677	G	T	SNP	TRAPPC12	ENST00000324266	human	ensembl	74_37	+1	known	nonsense	c.283	p.G95*	0.000	NULL	smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	TRAPPC12	HGNC	ENSG00000171853	tier1	-	-	20	0	0.00	7	3	30.00	0	0	0.00	0	0	0.00
CDON	0	genome.wustl.edu	37	11	125831880	125831880	+	Frame_Shift_Del	DEL	T	T	-			TCGA-Z4-A8JB-01A-23D-A37C-09	TCGA-Z4-A8JB-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	693ee45f-0cc9-45e1-8b05-bfb08253990a	ef7ae782-355b-4982-8713-82dfdb7e1fab	11	125831880	125831880	T	-	DEL	CDON	ENST00000392693	human	ensembl	74_37	-1	known	frame_shift_del	c.3370	p.T1124fs	1.000	NULL	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	CDON	HGNC	ENSG00000064309	tier1			34	0	0.00	21	2	8.70	120	0	0.00	175	2	1.13