Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
CAPN2	824	broad.mit.edu	37	1	223943324	223943324	+	Missense_Mutation	SNP	G	G	A			TCGA-FP-8210-01A-11D-2340-08	TCGA-FP-8210-11A-01D-2340-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	684ff3b4-a44b-46c5-8739-8dfcf614e534	5e6337c8-d4d5-48d8-9311-f286f2126e4e	g.chr1:223943324G>A	uc001hob.3	+	10	1502	c.1278G>A	c.(1276-1278)ATG>ATA	p.M426I	CAPN2_uc010puy.1_Missense_Mutation_p.M348I|CAPN2_uc001hoc.2_5'Flank	NM_001748	NP_001739	P17655	CAN2_HUMAN	calpain 2 isoform 1	426	Domain III.				proteolysis	cytoplasm|plasma membrane				lung(3)|breast(1)|skin(1)	5				GBM - Glioblastoma multiforme(131;0.109)		GCGAGGACATGCACACCATCG	0.532000												
SLC28A2	9153	broad.mit.edu	37	15	45564491	45564491	+	Splice_Site	SNP	A	A	G			TCGA-FP-8210-01A-11D-2340-08	TCGA-FP-8210-11A-01D-2340-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	684ff3b4-a44b-46c5-8739-8dfcf614e534	5e6337c8-d4d5-48d8-9311-f286f2126e4e	g.chr15:45564491A>G	uc001zva.2	+	16	1714	c.1649_splice	c.e16-2	p.T550_splice		NM_004212	NP_004203	O43868	S28A2_HUMAN	solute carrier family 28 (sodium-coupled						nucleobase, nucleoside and nucleotide metabolic process	integral to plasma membrane|membrane fraction	nucleoside binding|nucleoside:sodium symporter activity|purine nucleoside transmembrane transporter activity			ovary(4)	4		all_cancers(109;8.53e-07)|all_epithelial(112;1.39e-05)|Lung NSC(122;8.3e-05)|all_lung(180;0.000547)|Melanoma(134;0.0417)		all cancers(107;3.77e-16)|GBM - Glioblastoma multiforme(94;2.71e-06)		TATTGTCTGCAGCATCAATAG	0.483000												
TNRC6A	27327	broad.mit.edu	37	16	24834270	24834270	+	Missense_Mutation	SNP	G	G	A			TCGA-FP-8210-01A-11D-2340-08	TCGA-FP-8210-11A-01D-2340-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	684ff3b4-a44b-46c5-8739-8dfcf614e534	5e6337c8-d4d5-48d8-9311-f286f2126e4e	g.chr16:24834270G>A	uc002dmm.2	+	24	5563	c.5449G>A	c.(5449-5451)GGA>AGA	p.G1817R	TNRC6A_uc010bxs.2_Missense_Mutation_p.G1564R|TNRC6A_uc002dmn.2_Missense_Mutation_p.G1515R|TNRC6A_uc002dmo.2_Missense_Mutation_p.G1456R|TNRC6A_uc002dmr.2_Missense_Mutation_p.G16R	NM_014494	NP_055309	Q8NDV7	TNR6A_HUMAN	trinucleotide repeat containing 6A	1817	Sufficient for interaction with EIF2C2.|RRM.				negative regulation of translation involved in gene silencing by miRNA	cytoplasmic mRNA processing body|micro-ribonucleoprotein complex	nucleotide binding|RNA binding			ovary(2)	2				GBM - Glioblastoma multiforme(48;0.0394)		CCTCCCTCACGGAAATGCTCT	0.522000												
CDH1	999	broad.mit.edu	37	16	68844182	68844182	+	Missense_Mutation	SNP	A	A	G			TCGA-FP-8210-01A-11D-2340-08	TCGA-FP-8210-11A-01D-2340-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	684ff3b4-a44b-46c5-8739-8dfcf614e534	5e6337c8-d4d5-48d8-9311-f286f2126e4e	g.chr16:68844182A>G	uc002ewg.1	+	6	894	c.770A>G	c.(769-771)GAC>GGC	p.D257G	CDH1_uc010vlj.1_RNA|CDH1_uc010cfg.1_Missense_Mutation_p.D257G	NM_004360	NP_004351	P12830	CADH1_HUMAN	cadherin 1, type 1 preproprotein	257	Cadherin 1.|Extracellular (Potential).				adherens junction organization|cellular component disassembly involved in apoptosis|cellular response to indole-3-methanol|cellular response to lithium ion|homophilic cell adhesion|negative regulation of cell-cell adhesion|positive regulation of transcription factor import into nucleus|positive regulation of transcription, DNA-dependent|regulation of immune response	actin cytoskeleton|aggresome|apical junction complex|catenin complex|cell-cell adherens junction|endosome|focal adhesion|Golgi apparatus|integral to membrane|internal side of plasma membrane|lateral plasma membrane|perinuclear region of cytoplasm	cell adhesion molecule binding|gamma-catenin binding	p.?(2)|p.D257G(1)|p.D254fs*9(1)		breast(148)|stomach(71)|biliary_tract(8)|endometrium(3)|soft_tissue(2)|large_intestine(2)|urinary_tract(2)|oesophagus(2)|ovary(2)|thyroid(1)|central_nervous_system(1)|lung(1)	243		all_neural(199;0.0189)|Ovarian(137;0.0563)		Epithelial(162;8.44e-05)|all cancers(182;0.000404)|OV - Ovarian serous cystadenocarcinoma(108;0.000426)|BRCA - Breast invasive adenocarcinoma(181;0.0261)		GATCAGAATGACAACAAGCCC	0.463000			Mis|N|F|S		lobular breast|gastric	gastric			Hereditary_Diffuse_Gastric_Cancer			
NTSR2	23620	broad.mit.edu	37	2	11802136	11802136	+	Silent	SNP	G	G	A	rs148062399	byFrequency	TCGA-FP-8210-01A-11D-2340-08	TCGA-FP-8210-11A-01D-2340-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	684ff3b4-a44b-46c5-8739-8dfcf614e534	5e6337c8-d4d5-48d8-9311-f286f2126e4e	g.chr2:11802136G>A	uc002rbq.3	-	2	929	c.855C>T	c.(853-855)GAC>GAT	p.D285D		NM_012344	NP_036476	O95665	NTR2_HUMAN	neurotensin receptor 2	285	Cytoplasmic (Potential).				sensory perception	integral to plasma membrane					0	all_hematologic(175;0.127)|Acute lymphoblastic leukemia(172;0.155)			Epithelial(75;0.129)|OV - Ovarian serous cystadenocarcinoma(76;0.24)	Levocabastine(DB01106)	TCCGGCGCACGTCTTTATGTC	0.512000												
SLU7	10569	broad.mit.edu	37	5	159830390	159830390	+	Missense_Mutation	SNP	T	T	A			TCGA-FP-8210-01A-11D-2340-08	TCGA-FP-8210-11A-01D-2340-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	684ff3b4-a44b-46c5-8739-8dfcf614e534	5e6337c8-d4d5-48d8-9311-f286f2126e4e	g.chr5:159830390T>A	uc003lyg.2	-	16	1818	c.1663A>T	c.(1663-1665)ATG>TTG	p.M555L		NM_006425	NP_006416	O95391	SLU7_HUMAN	step II splicing factor SLU7	555					alternative nuclear mRNA splicing, via spliceosome|nuclear mRNA 3'-splice site recognition	catalytic step 2 spliceosome|cytoplasm|nuclear speck|small nuclear ribonucleoprotein complex	pre-mRNA 3'-splice site binding|second spliceosomal transesterification activity|zinc ion binding			ovary(1)	1	Renal(175;0.00196)	Medulloblastoma(196;0.0354)|all_neural(177;0.116)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			GTTTCATACATGCTATTGTAA	0.483000