Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID COSMIC_Codon COSMIC_Gene Transcript_Id Exon ChromChange AAChange Genome_Plus_Minus_10_Bp Drug_Target TTotCov_SOL TVarCov_SOL TVaf_SOL NTotCov_SOL NVarCov_SOL NVaf_SOL dbSNPPopFreq COSMIC_Gene_Freq COSMIC_Site_Freq Ttot_rna Tvar_rna Tvaf_rna note germline-maf-frequency IGV ESPNP 0 broad.mit.edu 37 1 17030903 17030905 + RNA DEL GAG GAG - rs55663095 alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 GAG GAG Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . . . . . ATCGACGAGGAGG 7 3 0.43 8 0 0 0 0 WASF2 10163 broad.mit.edu 37 1 27736343 27736343 + Silent SNP G G A rs200541363 TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . WASF2 NM_006990 exon8 c.C1182T p.P394P AGGAGGGGGAGGA 230 4 0.02 181 1 0.0055248619 41 48 0 0.00 CACHD1 57685 broad.mit.edu 37 1 65147783 65147783 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . CACHD1 NM_020925 exon26 c.G3427T p.D1143Y GAAAGTGATCATG 282 4 0.01 225 0 0 125 81 0 0.00 . 0 broad.mit.edu 37 1 143392853 143392853 + RNA DEL T T - novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . . . . . CTCTCATTTTTTT 8 3 0.38 10 0 0 0 0 CACNA1E 777 mdanderson.org 37 1 181767679 181767679 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001205293 exon48 c.G6651T p.Q2217H CCCCCAGCAGAGC 56 3 0.05 48 0 0 1 0 0.00 ZNF496 84838 mdanderson.org 37 1 247464565 247464565 + Silent SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_032752 exon9 c.G1020A p.P340P AGATCGCGGGTTG 51 3 0.06 28 0 0 96 0 0.00 RTKN2 219790 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 10 63957724 63957724 + Silent SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_145307 exon12 c.G1773A p.R591R TTTCTGCCTTGGA 165 67 0.41 154 0 0 5 3 0.60 MYPN 84665 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca;mdanderson.org 37 10 69881408 69881408 + Silent SNP A A G novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 A A Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 MYPN,NS,carcinoma,+2,1 MYPN NM_032578 exon2 c.A213G p.E71E AGAAGAATTAGAC 149 8 0.05 179 0 0 2 1 0 0 LRRC20 55222 mdanderson.org 37 10 72061201 72061201 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_207119 exon5 c.C464A p.P155Q TTGAGTGGGTTGA 61 3 0.05 66 0 0 5 0 0.00 ZNF503 84858 mdanderson.org 37 10 77159117 77159117 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_032772 exon2 c.C1331A p.A444E GCCGCCGCCCCTG 14 2 0.14 26 0 0 6 0 0.00 CNNM1 26507 mdanderson.org 37 10 101089397 101089397 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_020348 exon1 c.G253T p.A85S ACCGCCGCACCGG 13 3 0.23 14 0 0 0 0 KNDC1 85442 mdanderson.org 37 10 135012338 135012338 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_152643 exon14 c.G2326T p.A776S TCATCGGCAGCTC 12 2 0.17 18 0 0 4 0 0.00 MUC2 4583 mdanderson.org 37 11 1092960 1092960 + Silent SNP C C A novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_002457 exon30 c.C4779A p.T1593T GGTGACCCCAACC 21 4 0.19 26 1 0.0384615385 0 0 DCP1B 196513 broad.mit.edu;mdanderson.org 37 12 2062350 2062350 + Missense_Mutation SNP C C G novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 DCP1B,bladder,carcinoma,0,13 DCP1B NM_152640 exon7 c.G756C p.Q252H CTGCTGCTGGTGG 68 4 0.06 18 0 0 63 13 113 3 0.03 TUBA1A 7846 broad.mit.edu 37 12 49580272 49580274 + In_Frame_Del DEL GGA GGA - novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 GGA GGA Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . TUBA1A . . . . CAGGGGGGAGGAG 160 8 0.05 87 0 0 32 10 0 0.00 TENC1 23371 mdanderson.org 37 12 53442956 53442956 + Missense_Mutation SNP G G T rs12369033 bycluster;byfrequency;by2hit2allele;by1000genomes;alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_015319 exon1 c.G29T p.R10M TTGGGAGGGGGGA 109 3 0.03 49 0 0 0 0 KBTBD7 84078 mdanderson.org 37 13 41767097 41767097 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_032138 exon1 c.C1297A p.L433I CATTGAGATATGC 140 6 0.04 153 1 0.0065359477 19 0 0.00 CRAMP1L 57585 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 16 1703072 1703072 + Missense_Mutation SNP C C A novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_020825 exon7 c.C952A p.P318T CGCCTGCCTCTGA 100 14 0.14 83 0 0 6 0 0.00 FAM86A 196483 ucsc.edu 37 16 5140488 5140488 + Missense_Mutation SNP C C T rs200021489 byfrequency TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic RNA-Seq none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . FAM86A NM_201400 exon5 c.G421A p.A141T GGGCGGCGTCCCA 195 4 0.02 194 1 0.0051546392 32 27 9 0.33 rescued with RNA-seq ITGAL 3683 mdanderson.org 37 16 30510736 30510736 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_002209 exon17 c.G2071T p.G691W CCAGGAGGGAGAC 52 3 0.06 74 0 0 11 0 0.00 HEATR3 55027 mdanderson.org 37 16 50112705 50112705 + Missense_Mutation SNP A A T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_182922 exon7 c.A817T p.I273L GAAATCATAAATG 57 3 0.05 84 0 0 41 1 0.02 KRTAP1-1 81851 broad.mit.edu 37 17 39197304 39197304 + Missense_Mutation SNP T T C novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 KRTAP1-1,NS,malignant_melanoma,0,1 KRTAP1-1 NM_030967 exon1 c.A346G p.I116V ACCTGATACGGGT 108 3 0.03 87 0 0 23 1 0 0 KRTAP9-9 81870 hgsc.bcm.edu 37 17 39411694 39411694 + Missense_Mutation SNP G G C novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 KRTAP9-9,NS,carcinoma,+2,1 KRTAP9-9 NM_030975 exon1 c.G57C p.W19C CTGCTGGAAGCCC 110 8 0.07 68 1 0.0147058824 2 1 0 0 EFCAB13 124989 broad.mit.edu 37 17 45455146 45455146 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_152347 exon13 c.G1387T p.A463S TGTGAAGCTATCA 535 7 0.01 348 1 0.0028735632 3 0 0.00 MRC2 9902 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 17 60743604 60743604 + Missense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_006039 exon3 c.C670T p.R224C GACGAGCGCTGGG 58 10 0.17 53 0 0 49 16 0.33 KLHL14 57565 mdanderson.org 37 18 30350531 30350531 + Silent SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_020805 exon2 c.C24A p.T8T GGTGGAGGTCCTG 15 2 0.13 18 0 0 0 0 PRAM1 84106 mdanderson.org 37 19 8563401 8563401 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_032152 exon2 c.C1291A p.P431T GGCCTGGCCTGGC 38 3 0.08 45 0 0 3 0 0.00 PALM3 342979 mdanderson.org 37 19 14166230 14166230 + Missense_Mutation SNP C C T rs372500968 TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001145028 exon5 c.G362A p.R121H AGAGGACGGTGAC 45 3 0.07 52 0 0 30 0 0.00 WDR87 83889 broad.mit.edu 37 19 38377225 38377225 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . WDR87 NM_031951 exon6 c.C6969A p.D2323E TTCCTCGTCACTC 448 5 0.01 444 0 0 191 7 0 0.00 CLASRP 11129 mdanderson.org 37 19 45556058 45556058 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_007056 exon4 c.G207T p.W69C GCCCTGGCAGGGG 70 4 0.06 77 0 0 95 0 0.00 UBE2M 9040 broad.mit.edu 37 19 59067587 59067587 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . UBE2M NM_003969 exon6 c.C421A p.P141T CCTCGGGGTTGGG 187 5 0.03 153 0 0 14 580 0 0.00 . 0 broad.mit.edu 37 2 38710046 38710047 + RNA DNP TA TA AT novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 TA TA Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . . . . . AAATAATAAATAA 58 6 0.10 56 1 0.0178571429 0 0 HIBCH 26275 ucsc.edu 37 2 191161637 191161637 + Missense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic RNA-Seq none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . HIBCH NM_014362 exon3 c.G121A p.E41K TTTTTTCCAATAG 173 1 0.01 174 1 0.0057471264 28 40 5 0.13 ADNP 23394 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;mdanderson.org 37 20 49509508 49509508 + Nonsense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_015339 exon5 c.C1743A p.Y581X GGCATGGTAAGCA 171 54 0.32 108 0 0 154 54 0.35 ZNRF3 84133 mdanderson.org 37 22 29446468 29446468 + Missense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001206998 exon8 c.C2299T p.P767S CATTTGCCCAGGA 51 3 0.06 53 0 0 39 0 0.00 ODF3B 440836 broad.mit.edu;mdanderson.org 37 22 50969176 50969176 + Nonsense_Mutation SNP G G T rs371794773 alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . ODF3B NM_001014440 exon6 c.C646A p.R216R GCTTCCGAGTGTT 92 4 0.04 85 0 0 6 39 0 0.00 BRPF1 7862 hgsc.bcm.edu;broad.mit.edu;mdanderson.org 37 3 9783003 9783003 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001003694 exon5 c.G1734T p.E578D TTCTGAGGATAAG 73 4 0.05 67 0 0 29 0 0.00 FGD5 152273 broad.mit.edu 37 3 14941958 14941958 + Missense_Mutation SNP A A G novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . FGD5 NM_152536 exon8 c.A3203G p.Q1068R ACACACAGGGTGA 286 7 0.02 255 0 0 248 3 0 0.00 CACNA1D 776 broad.mit.edu 37 3 53839099 53839099 + Missense_Mutation SNP A A G novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . CACNA1D NM_000720 exon46 c.A5735G p.E1912G TCTTGGAGGACGA 89 3 0.03 64 1 0.015625 324 0 0 PRICKLE2 166336 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 3 64133021 64133021 + Missense_Mutation SNP G G A novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 PRICKLE2,colon,carcinoma,-1,1 PRICKLE2 NM_198859 exon7 c.C1145T p.S382F TGGCTGGACAGGC 78 35 0.45 80 0 0 -1 1 2 0 0.00 MYH15 22989 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 3 108189650 108189650 + Missense_Mutation SNP C C G novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_014981 exon14 c.G1338C p.R446S AAACATCCTTTCA 170 24 0.14 140 0 0 0 0 MED12L 116931 broad.mit.edu 37 3 150881773 150881773 + Nonsense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . MED12L NM_053002 exon8 c.C1201T p.Q401X CTGCTGCAGGTGG 181 4 0.02 130 0 0 271 7 0 0.00 FGF12 2257 mdanderson.org 37 3 192125818 192125818 + Silent SNP T T C novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_021032 exon1 c.A195G p.R65R ACCTGGTCTCCGC 43 3 0.07 48 0 0 1 0 0.00 GAK 2580 mdanderson.org 37 4 877844 877844 + Nonsense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_005255 exon12 c.C1236A p.Y412X TGTGATGTAAGAT 86 4 0.05 70 0 0 64 0 0.00 WHSC1 7468 mdanderson.org 37 4 1978397 1978397 + Missense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_133335 exon21 c.C3817T p.R1273W GGCAAGCGGCCCT 51 3 0.06 60 0 0 40 0 0.00 HTT 3064 broad.mit.edu 37 4 3076604 3076606 + In_Frame_Del DEL CAG CAG - rs10618869 alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 CAG CAG Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . HTT NM_002111 exon1 c.52_54del p.18_18del TCCTTCCAGCAGC 8 3 0.38 6 0 0 221 4 0 0.00 TRIO 7204 mdanderson.org 37 5 14507271 14507271 + Nonsense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_007118 exon56 c.G8653T p.G2885X CGATGGGGAAGCC 37 3 0.08 40 0 0 24 0 0.00 MEGF10 84466 broad.mit.edu 37 5 126758405 126758405 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . MEGF10 NM_032446 exon14 c.G1634T p.S545I ACTGCAGCCACGC 140 7 0.05 147 2 0.0136054422 152 2 0 0.00 HIST1H4A 8359 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 6 26021940 26021940 + Missense_Mutation SNP G G A novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_003538 exon1 c.G34A p.G12S GGTTTGGGTAAGG 131 13 0.10 132 0 0 0 0 MUC21 394263 broad.mit.edu 37 6 30954813 30954813 + Silent SNP T T C rs9262371 bycluster;by1000genomes TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . MUC21 NM_001010909 exon2 c.T861C p.N287N CACCAATTCTGAG 66 4 0.06 82 1 0.012195122 98 0 0 ANKRD6 22881 broad.mit.edu 37 6 90276712 90276712 + Missense_Mutation SNP C C T rs200814043 by1000genomes;alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . ANKRD6 NM_001242809 exon2 c.C17T p.A6V AAGATGCGGTCGC 273 6 0.02 223 2 0.0089686099 51 4 0 0.00 TTLL2 83887 mdanderson.org 37 6 167754661 167754661 + Nonsense_Mutation SNP A A T rs909545 bycluster;byfrequency;bysubmitter;by2hit2allele;byhapmap;by1000genomes;alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_031949 exon3 c.A1273T p.R425X GAGGGGAGAGAAG 105 3 0.03 98 0 0 0 0 SDK1 221935 broad.mit.edu 37 7 3681699 3681699 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 SDK1,bladder,carcinoma,+1,1 SDK1 NM_152744 exon4 c.G675T p.W225C GACTTGGTTTAGA 130 5 0.04 118 0 0 361 1 3 0 0.00 SP8 221833 broad.mit.edu;mdanderson.org 37 7 20824970 20824970 + Missense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . SP8 NM_182700 exon2 c.G466A p.G156S CGCCGCCGCTGCC 59 4 0.07 46 0 0 43 2 0 0.00 BBS9 27241 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca 37 7 33407379 33407380 + Frame_Shift_Ins INS - - T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 - - Unknown Untested Somatic . WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . BBS9 NM_198428 exon17 c.1694_1695insT p.G565fs TTGTAGGTTTTGC 116 39 0.34 133 0 0 194 20 0 0.00 CCT6P1 0 broad.mit.edu 37 7 65226641 65226641 + RNA SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . . . . . TCTTGCGCAGAAT 217 6 0.03 122 0 0 17 0 0.00 PON1 5444 broad.mit.edu 37 7 94944672 94944672 + Nonsense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 PON1,NS,carcinoma,0,1 PON1 NM_000446 exon4 c.C332A p.S111X TTAAATGAAGATA 272 5 0.02 180 1 0.0055555556 55 1 0 0 ZAN 7455 broad.mit.edu 37 7 100349865 100349865 + RNA SNP T T C novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . ZAN . . . . ACCATCTCCCCAG 221 15 0.07 111 5 0.045045045 658 3 0 0.00 MUC17 140453 broad.mit.edu 37 7 100686191 100686191 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . MUC17 NM_001040105 exon3 c.G11494T p.A3832S TCTGAGGCCAGCA 152 4 0.03 82 0 0 804 0 0 TRIM24 8805 broad.mit.edu 37 7 138239517 138239517 + Nonsense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . TRIM24 NM_003852 exon9 c.C1336T p.Q446X AATTCACAGCCAC 641 5 0.01 384 1 0.0026041667 131 88 0 0.00 YWHAZ 7534 mdanderson.org 37 8 101960892 101960892 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001135699 exon2 c.C226A p.Q76K TCTGCTGTTTTTT 52 3 0.06 40 1 0.025 2114 3 0.00 PRSS3 5646 mdanderson.org 37 9 33794809 33794809 + Missense_Mutation SNP G G A rs201061108 TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001197097 exon2 c.G20A p.S7N AGACAAGTGGCTT 90 15 0.17 60 2 0.0333333333 0 0 RGS3 5998 broad.mit.edu 37 9 116303614 116303614 + Missense_Mutation SNP C C G rs201201135 by1000genomes;alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . RGS3 NM_017790 exon18 c.C1716G p.F572L CCCTTTCGGCTCT 90 4 0.04 88 0 0 251 0 0 IGSF1 3547 broad.mit.edu 37 X 130412689 130412689 + Missense_Mutation SNP G G T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . IGSF1 NM_001170961 exon12 c.C1802A p.A601E GTCTCTGCCCACA 264 5 0.02 155 0 0 231 40 0 0.00 ARHGAP4 393 mdanderson.org 37 X 153174574 153174574 + Silent SNP G G T rs202239294 alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . NM_001164741 exon22 c.C2677A p.R893R AGCGTCGTCTGTG 55 3 0.05 34 0 0 70 0 0.00 DNAH11 8701 mdanderson.org 37 7 21745108 21745108 + Missense_Mutation SNP C C T novel TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 DNAH11,NS,carcinoma,-1,1 DNAH11 . . . . GCTGTGCGGCACT 130 5 0.04 138 0 0 -1 1 0 0 DNAH11 8701 mdanderson.org 37 7 21924014 21924014 + Missense_Mutation SNP A A T rs6461613 bycluster;byfrequency;by2hit2allele;byhapmap;by1000genomes;alternate_allele TCGA-2G-AAFI-01A-21D-A42Y-10 TCGA-2G-AAFI-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq f9480516-f59c-493a-af4e-826e35d4967f 78f10599-cf46-4998-be34-08693afd06f2 . . . . . . GAATTCATGAATC 95 2 0.02 114 0 0 0 0