Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID COSMIC_Codon COSMIC_Gene Transcript_Id Exon ChromChange AAChange Genome_Plus_Minus_10_Bp Drug_Target TTotCov_SOL TVarCov_SOL TVaf_SOL NTotCov_SOL NVarCov_SOL NVaf_SOL dbSNPPopFreq COSMIC_Gene_Freq COSMIC_Site_Freq Ttot_rna Tvar_rna Tvaf_rna note germline-maf-frequency IGV TAS1R3 83756 mdanderson.org 37 1 1267771 1267771 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_152228 exon3 c.G860T p.S287I ACTACAGCATCAG 48 3 0.06 46 0 0 0 0 . 0 bcgsc.ca 37 1 79215807 79215807 + RNA SNP C C G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . GCATGACAGGCGA 83 5 0.06 50 0 0 0 0 NOTCH2 4853 broad.mit.edu 37 1 120458445 120458445 + Silent SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . NOTCH2 NM_024408 exon34 c.C6900A p.P2300P GGGCAAGGGCTCC 75 3 0.04 36 0 0 348 54 0 0.00 CCDC3 83643 mdanderson.org 37 10 13043391 13043391 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_031455 exon1 c.C180A p.N60K CAGGTGGTTGTAG 48 3 0.06 42 0 0 10 0 0.00 PDE3B 5140 mdanderson.org 37 11 14666437 14666437 + Silent SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_000922 exon1 c.G816T p.A272A GGAAGCGCCTCTT 44 3 0.07 84 0 0 18 1 0.06 MYBPC3 4607 mdanderson.org 37 11 47372906 47372906 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_000256 exon2 c.C176T p.T59I CCCTCTGTGGCCA 52 3 0.06 69 0 0 0 0 LOC440040 0 broad.mit.edu 37 11 49831251 49831258 + RNA DEL TTATTTAT TTATTTAT - rs71918870 alternate_allele TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 TTATTTAT TTATTTAT Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TCTTTCTTATTTA 15 5 0.33 9 0 0 0 0 LRP5 4041 broad.mit.edu 37 11 68207377 68207377 + Missense_Mutation SNP A A C novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . LRP5 NM_002335 exon21 c.A4481C p.Y1494S CGCTGTACCCGCC 11 5 0.45 30 14 0.4666666667 136 26 1 0.04 SHANK2 22941 ucsc.edu 37 11 70653168 70653168 + Nonsense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . SHANK2 . . . . TGGCTTGACAGCG 66 11 0.17 120 6 0.05 340 0 0 TENM4 26011 mdanderson.org 37 11 78565254 78565254 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001098816 exon12 c.C1576A p.H526N TCTCATGGCTGGA 19 2 0.11 37 0 0 8 0 0.00 GRM5 2915 mdanderson.org 37 11 88300321 88300321 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 GRM5_ENST00000418177,NS,carcinoma,0,2 GRM5_ENST00000418177 NM_000842 exon8 c.C2530A p.R844S GCATGCGCACCAC 37 3 0.08 80 0 0 0 2 0 0 FAM60A 58516 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 12 31440707 31440707 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_021238 exon6 c.C367T p.H123Y TACTGTGAGCATC 101 14 0.14 47 0 0 670 114 0.17 ATF7 11016 mdanderson.org 37 12 53918523 53918523 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_006856 exon10 c.C950A p.P317H GTACTAGGGGTGG 22 2 0.09 27 0 0 25 0 0.00 CCDC64 92558 mdanderson.org 37 12 120518734 120518734 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_207311 exon7 c.G1352T p.R451I AGGAGAGAGACCG 45 4 0.09 30 0 0 29 0 0.00 RPLP0 6175 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 12 120637138 120637138 + Silent SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_053275 exon3 c.C205T p.L69L TTTCCAGGTGCCC 101 20 0.20 86 0 0 42352 12145 0.29 SACS 26278 broad.mit.edu 37 13 23907043 23907043 + Missense_Mutation SNP G G A rs115155117 bycluster;by1000genomes TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . SACS NM_014363 exon10 c.C10972T p.R3658W GGGCCCGCTCAGG 68 3 0.04 56 0 0 871 19 0 0.00 . 374491 bcgsc.ca 37 13 25144704 25144704 + RNA SNP T T C rs9551120 bycluster;byfrequency;by2hit2allele;byhapmap;by1000genomes TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TAGATGTGTTTAA 42 25 0.60 58 6 0.1034482759 0 0 . 374491 bcgsc.ca 37 13 25144710 25144710 + RNA SNP A A G rs3742170 bycluster;byhapmap TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TGTTTAACACAGC 44 27 0.61 59 7 0.1186440678 0 0 . 374491 bcgsc.ca 37 13 25144712 25144712 + RNA SNP A A C rs3742169 bycluster;byhapmap;by1000genomes TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TTTAACACAGCCC 48 29 0.60 63 8 0.126984127 0 0 SLC25A15 10166 mdanderson.org 37 13 41373332 41373332 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_014252 exon3 c.G195T p.K65N CTACAAGGGTACC 142 5 0.04 172 0 0 34 0 0.00 ZC3H13 23091 mdanderson.org 37 13 46562935 46562935 + Missense_Mutation SNP A A T rs1134071 bycluster;byfrequency;byhapmap;by1000genomes;alternate_allele TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_015070 exon9 c.T1242A p.H414Q CCTTTCATGGCGT 62 2 0.03 85 0 0 82 0 0.00 TRIM13 10206 hgsc.bcm.edu 37 13 50588497 50588500 + RNA DEL ACAC ACAC - rs10676627 alternate_allele TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 ACAC ACAC Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . TRIM13 . . . . ATATATACACACA 27 16 0.59 23 0 0 30 1 0 0.00 ATP5S 27109 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 14 50789405 50789405 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_015684 exon3 c.C329T p.S110F CCGACTCTTGTAT 132 30 0.23 122 0 0 59 22 0.37 PLEKHG3 26030 mdanderson.org 37 14 65209934 65209934 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_015549 exon15 c.C3005T p.A1002V AGTATGCCTCCCG 27 3 0.11 36 0 0 16 0 0.00 ISM2 145501 broad.mit.edu;bcgsc.ca;mdanderson.org 37 14 77950769 77950769 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 ISM2,colon,carcinoma,+1,1 ISM2 NM_199296 exon3 c.C524T p.A175V GGCGTGGCATTCC 129 6 0.05 105 0 0 68 1 9 0 0.00 FAM181A 90050 mdanderson.org 37 14 94395420 94395420 + Silent SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_138344 exon3 c.G975T p.G325G CCTGGGGCAGAAG 35 3 0.09 33 0 0 0 0 MIR655 0 broad.mit.edu 37 14 101514904 101514905 + RNA DEL GT GT - rs374284110 alternate_allele TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 GT GT Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TCTGGGGTGTGTG 35 9 0.26 31 0 0 0 0 EID1 23741 mdanderson.org 37 15 49170510 49170510 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_014335 exon1 c.G137A p.R46H CCTCCCGCAGCGG 39 3 0.08 52 0 0 253 0 0.00 MESP2 145873 hgsc.bcm.edu 37 15 90320132 90320132 + Missense_Mutation SNP C C G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 MESP2,NS,carcinoma,-2,1 MESP2 NM_001039958 exon1 c.C544G p.Q182E CAGGGGCAAGGGC 32 2 0.06 15 0 0 -2 1 0 0 MESP2 145873 broad.mit.edu;mdanderson.org 37 15 90320173 90320173 + Silent SNP A A G rs113636330 TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . MESP2 NM_001039958 exon1 c.A585G p.G195G GCAAGGACAGGGG 38 2 0.05 21 0 0 20 1 0 0.00 PRSS41 360226 mdanderson.org 37 16 2849000 2849000 + Silent SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001135086 exon2 c.C171T p.G57G GGCGGGCGGAGTG 16 3 0.19 13 0 0 1 0 0.00 NLRC3 197358 broad.mit.edu 37 16 3601981 3601982 + RNA INS - - CACC rs113120190 bycluster;by1000genomes TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 - - Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . NLRC3 . . . . CTTCATTCATCCA 17 8 0.47 11 0 0 103 0 0 SEC14L5 9717 mdanderson.org 37 16 5041986 5041986 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_014692 exon6 c.C622T p.P208S CACGGGCCCCGTA 31 3 0.10 16 0 0 3 0 0.00 UBFD1 56061 broad.mit.edu 37 16 23568933 23568933 + Missense_Mutation SNP T T G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . UBFD1 . . . . GGCGGGTCTCCAT 42 15 0.36 21 7 0.3333333333 16 2 0 0.00 ARHGAP17 55114 ucsc.edu 37 16 24965936 24965936 + Silent SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . ARHGAP17 NM_001006634 exon10 c.C840T p.G280G CTTCATGCCTGTC 41 4 0.10 43 0 0 138 68 0 0.00 TAOK2 9344 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 16 29998788 29998788 + Silent SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 TAOK2_ENST00000308893,colon,carcinoma,+1,1 TAOK2_ENST00000308893 NM_016151 exon16 c.G3195A p.A1065A GGCAGCGGGGGGC 89 23 0.26 82 0 0 1 1 80 27 0.34 PHKB 5257 mdanderson.org 37 16 47622988 47622988 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_000293 exon10 c.G1043T p.C348F ACAGATGCTACTA 64 4 0.06 62 0 0 60 0 0.00 LOC283922 0 broad.mit.edu 37 16 74366343 74366343 + RNA SNP T T C rs112075144 bycluster;byfrequency TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . CCTCAGTTCCCAA 36 9 0.25 24 1 0.0416666667 5 0 0.00 POLR2A 5430 broad.mit.edu 37 17 7407047 7407047 + Silent SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . POLR2A NM_000937 exon19 c.G3177T p.R1059R GTTTCGGCTCAGT 257 4 0.02 209 0 0 157 196 0 0.00 GUCY2D 3000 mdanderson.org 37 17 7909965 7909965 + Silent SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_000180 exon4 c.G1311T p.P437P CTTCCCGCGTGGG 51 3 0.06 56 0 0 0 0 ACACA 31 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 17 35445916 35445916 + Missense_Mutation SNP T T G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 ACACA_ENST00000353139,bladder,carcinoma,+2,2 ACACA_ENST00000353139 NM_198834 exon55 c.A6985C p.I2329L ATTTGATGTTTTC 302 83 0.27 273 0 0 2 2 232 87 0.38 CDH19 28513 bcgsc.ca;mdanderson.org 37 18 64172301 64172301 + Silent SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . CDH19 NM_021153 exon12 c.C2067T p.G689G GTCGGGGCCAACT 89 5 0.06 99 0 0 141 1 0 0.00 ACTL9 284382 mdanderson.org 37 19 8808404 8808404 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 ACTL9,NS,carcinoma,0,2 ACTL9 NM_178525 exon1 c.C648A p.H216Q CGTGGCGTGGAGC 15 2 0.13 13 0 0 0 2 0 0 ZNF433 163059 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 19 12126012 12126012 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001080411 exon4 c.C1670T p.T557I TCTCCAGTGTGAG 171 55 0.32 137 0 0 21 9 0.43 ZNF99 7652 hgsc.bcm.edu 37 19 22941279 22941279 + Missense_Mutation SNP C C G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 ZNF99,NS,carcinoma,0,1 ZNF99 NM_001080409 exon4 c.G1432C p.E478Q GTTTCTCTCCAGT 62 3 0.05 50 1 0.02 0 1 13 0 0.00 RHPN2 85415 mdanderson.org 37 19 33517507 33517507 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 RHPN2,face,carcinoma,0,2 RHPN2 NM_033103 exon3 c.G217A p.V73M GCCGCACTTGCTC 25 3 0.12 19 0 0 0 2 26 0 0.00 WBP1 23559 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca;mdanderson.org 37 2 74685732 74685732 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_012477 exon1 c.G3A p.M1I AGGTATGGCTCGG 152 44 0.29 111 0 0 134 29 0.22 DBI 1622 mdanderson.org 37 2 120129839 120129839 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001178017 exon4 c.C392T p.A131V AAGATGCCATGAA 42 3 0.07 38 0 0 911 0 0.00 NR4A2 4929 mdanderson.org 37 2 157183293 157183293 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_006186 exon6 c.C1298A p.A433D TGGTCGGCTTTGG 47 3 0.06 58 0 0 9 0 0.00 DGKD 8527 mdanderson.org 37 2 234370999 234370999 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_152879 exon25 c.G2987T p.R996L GTATCCGAGAAAT 47 3 0.06 37 0 0 140 0 0.00 ACTL10 170487 mdanderson.org 37 20 32255441 32255441 + Silent SNP C C T rs147746551 bycluster;byfrequency;by1000genomes;alternate_allele TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001024675 exon1 c.C138T p.N46N ACTGAACGTGGCA 46 3 0.07 56 0 0 0 0 IFNAR2 3455 broad.mit.edu 37 21 34635615 34635615 + Missense_Mutation SNP T T C novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . IFNAR2 NM_207585 exon9 c.T1358C p.L453P CTCATCTGGAAGA 146 4 0.03 79 0 0 44 35 0 0.00 CARD10 29775 broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 22 37903924 37903924 + Missense_Mutation SNP C C T rs150236189 byfrequency TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . CARD10 NM_014550 exon6 c.G1103A p.R368H AGCGTGCGGTGCT 132 63 0.48 115 1 0.0086956522 55 77 50 0.65 ADSL 158 broad.mit.edu 37 22 40757555 40757555 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . ADSL NM_001123378 exon9 c.G926A p.R309H TTGCCCGCCACCT 93 4 0.04 64 0 0 98 974 0 0.00 RHOA 387 ucsc.edu 37 3 49399927 49399927 + Splice_Site SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic RNA-Seq none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . RHOA NM_001664 exon5 c.408+2C>A . GATCATGCCTGCT 88 1 0.01 88 0 0 46 43 4 0.09 . 0 broad.mit.edu 37 3 59087570 59087570 + RNA DEL A A - novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . AATGCGAAAAAGA 6 2 0.33 7 0 0 0 0 ANAPC10 10393 broad.mit.edu 37 4 145916698 145916698 + Missense_Mutation SNP T T C novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . ANAPC10 NM_001256709 exon7 c.A418G p.K140E GCTTCTTATGATT 112 3 0.03 171 0 0 12 123 0 0.00 C5orf56 441108 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 5 131811504 131811504 + RNA SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . GGACACCGCGTCT 51 19 0.37 51 0 0 4 0 0.00 HK3 3101 mdanderson.org 37 5 176308126 176308126 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 HK3,NS,carcinoma,+1,1 HK3 NM_002115 exon19 c.C2720T p.A907V AGGGCCGCACCTT 38 3 0.08 66 0 0 1 1 1 0 0.00 OR2Y1 134083 bcgsc.ca 37 5 180166235 180166235 + Missense_Mutation SNP A A G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . OR2Y1 NM_001001657 exon1 c.T824C p.L275P TAAAAAAGGGCAA 48 4 0.08 71 0 0 49 0 0 UFL1 23376 broad.mit.edu 37 6 96997435 96997435 + Silent SNP A A G novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_015323 exon14 c.A1668G p.K556K TGAAAAAGGGATG 109 3 0.03 112 0 0 30 0 0.00 QKI 9444 mdanderson.org 37 6 163983060 163983060 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_206855 exon5 c.C593T p.A198V AGCTTGCGATTCT 46 3 0.07 54 0 0 180 0 0.00 INTS1 26173 ucsc.edu 37 7 1519274 1519274 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . INTS1 NM_001080453 exon31 c.G4121A p.R1374H ACGGGGCGGGGAC 25 4 0.16 20 0 0 145 53 0 0.00 SNX8 29886 mdanderson.org 37 7 2304059 2304059 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 SNX8,NS,carcinoma,+1,1 SNX8 NM_013321 exon6 c.C656T p.A219V CTGATGGCAAACT 31 3 0.10 28 0 0 1 1 336 0 0.00 TNRC18 84629 mdanderson.org 37 7 5364801 5364801 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001080495 exon20 c.G6226A p.A2076T GAGGAGCCCTGGC 39 3 0.08 28 0 0 49 0 0.00 CCT6P1 0 broad.mit.edu 37 7 65226641 65226641 + RNA SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TCTTGCGCAGAAT 129 3 0.02 111 3 0.027027027 25 0 0.00 KLRG2 346689 mdanderson.org 37 7 139168282 139168282 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_198508 exon1 c.C107A p.A36E ACCTTCGCGGGCA 30 3 0.10 22 0 0 288 0 0.00 MLL3 58508 mdanderson.org 37 7 151945313 151945313 + Silent SNP A A G rs372718879 bycluster TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_170606 exon14 c.T2206C p.L736L CCATCAATCCAGT 166 14 0.08 111 1 0.009009009 29 0 0.00 FGF20 26281 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 8 16853180 16853180 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 FGF20,leg,malignant_melanoma,0,1 FGF20 NM_019851 exon2 c.G374A p.G125E AGTTCTCCTTTGT 143 35 0.24 82 0 0 0 1 0 0 DUSP4 1846 mdanderson.org 37 8 29207485 29207485 + Missense_Mutation SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001394 exon1 c.C311T p.A104V ATGACCGCCGAGT 39 3 0.08 22 0 0 0 0 DOCK8 81704 mdanderson.org 37 9 396818 396818 + Missense_Mutation SNP G G T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_203447 exon25 c.G3004T p.D1002Y AACATGGACAAAC 74 4 0.05 114 0 0 14 0 0.00 . 441420 bcgsc.ca 37 9 45376206 45376206 + RNA SNP A A C rs372171742 TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 A A Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . GGACCAAACCAAC 46 8 0.17 40 2 0.05 2 0 0.00 LINC00475 0 broad.mit.edu 37 9 94907350 94907351 + RNA INS - - T rs112532694 bycluster;by1000genomes TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 - - Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . TTTCTTCTTTTTT 8 6 0.75 5 0 0 0 0 WNK2 65268 bcgsc.ca 37 9 95947703 95947703 + Missense_Mutation SNP G G T rs369083880 alternate_allele TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . WNK2 NM_006648 exon1 c.G492T p.E164D GCCTGAGCCCGGG 44 4 0.09 38 0 0 277 23 0 0.00 VCX3B 425054 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca;mdanderson.org 37 X 8434340 8434340 + Silent SNP G G A novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001001888 exon3 c.G657A p.Q219Q GAGCCAGGTGGAG 434 179 0.41 289 1 0.0034602076 62 7 0.11 NUDT10 170685 broad.mit.edu 37 X 51076024 51076024 + Silent SNP G G A rs2801626 TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . NUDT10 NM_153183 exon2 c.G207A p.E69E CGAAGAGGCGGGA 341 8 0.02 203 1 0.0049261084 28 109 0 0.00 SPIN2B 474343 broad.mit.edu 37 X 57146615 57146615 + Missense_Mutation SNP T T C novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . SPIN2B NM_001006683 exon2 c.A448G p.M150V AGACCATCCCCCT 541 7 0.01 349 1 0.0028653295 11 13 0 0.00 HS6ST2 90161 mdanderson.org 37 X 132092425 132092425 + Missense_Mutation SNP T T C novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . NM_001077188 exon2 c.A206G p.D69G GGCTTGTCCAGGA 16 3 0.19 13 0 0 0 0 CYP21A2 1589 mdanderson.org 37 6 32008888 32008888 + Missense_Mutation SNP C C T novel TCGA-2G-AAHG-01A-11D-A42Y-10 TCGA-2G-AAHG-10A-01D-A433-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 10eaeb31-4b4d-4a4e-b429-25eaf4d45fa9 6a857e34-f9b6-4512-980b-8bc82ecddee7 . . . . . . GGGGCCCACAGCC 21 2 0.10 11 0 0 0 0