Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID COSMIC_Codon COSMIC_Gene Transcript_Id Exon ChromChange AAChange Genome_Plus_Minus_10_Bp Drug_Target TTotCov_SOL TVarCov_SOL TVaf_SOL NTotCov_SOL NVarCov_SOL NVaf_SOL dbSNPPopFreq COSMIC_Gene_Freq COSMIC_Site_Freq Ttot_rna Tvar_rna Tvaf_rna note germline-maf-frequency IGV LDLRAP1 26119 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 1 25880446 25880446 + Missense_Mutation SNP C C T rs142920998 alternate_allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_015627 exon2 c.C122T p.T41M GGGAGACGCTGCT 76 21 0.28 56 0 0 44 12 0.27 DOCK7 85440 broad.mit.edu;mdanderson.org 37 1 63021531 63021531 + Missense_Mutation SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 DOCK7,caecum,carcinoma,0,2 DOCK7 NM_001271999 exon21 c.G2561A p.R854H GGTAGGCGGAAAA 34 3 0.09 46 0 0 184 2 23 7 0.30 KCND3 3752 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 1 112524653 112524653 + Silent SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 KCND3_ENST00000315987,NS,carcinoma,0,2 KCND3_ENST00000315987 NM_004980 exon2 c.G696A p.A232A GACGCACGCCGTG 54 13 0.24 65 0 0 0 2 0 0 OR13A1 79290 mdanderson.org 37 10 45799527 45799527 + Missense_Mutation SNP C C T rs115582445 bycluster;byfrequency;by1000genomes;alternate_allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001004297 exon4 c.G344A p.C115Y GCCATGCAGCCCC 48 3 0.06 94 0 0 0 0 TET1 80312 hgsc.bcm.edu;mdanderson.org 37 10 70333543 70333543 + Nonsense_Mutation SNP C C G novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_030625 exon2 c.C1448G p.S483X CAAACTCAGAGAA 84 7 0.08 99 0 0 12 3 0.25 PHLDA2 7262 broad.mit.edu 37 11 2950513 2950513 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 PHLDA2,brain,primitive_neuroectodermal_tumour-medulloblastoma,0,1 PHLDA2 NM_003311 exon1 c.C82A p.R28S CCCCGCGCTTCTT 54 4 0.07 82 1 0.012195122 10 1 8 0 0.00 ZNF215 7762 mdanderson.org 37 11 6953825 6953825 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_013250 exon3 c.G322T p.V108L ACTTGGGTGAATT 49 3 0.06 69 0 0 7 0 0.00 SCUBE2 57758 mdanderson.org 37 11 9082017 9082017 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001170690 exon8 c.C905A p.T302K ACACCTGTCGAAG 50 3 0.06 59 0 0 0 0 LDHAL6A 160287 mdanderson.org 37 11 18500372 18500372 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_144972 exon7 c.G954T p.K318N GCAAAAGAGTGCA 19 3 0.16 38 0 0 0 0 BDNF-AS 497258 hgsc.bcm.edu 37 11 27681201 27681201 + RNA SNP C C T rs182322619 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . . . . . TGCGCGCGCGCGT 62 9 0.15 115 0 0 1 0 0.00 TMEM132A 54972 mdanderson.org 37 11 60698068 60698068 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_017870 exon5 c.G953T p.G318V TCAAGGGCTCCAG 37 3 0.08 39 0 0 122 0 0.00 TAS2R20 259295 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca 37 12 11150095 11150096 + Frame_Shift_Del DEL CT CT - novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 CT CT Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . TAS2R20 NM_176889 exon1 c.380_381del p.127_127del ACTACACTCTTAG 214 30 0.14 119 0 0 17 1 0 0.00 PRB4 5545 broad.mit.edu 37 12 11461592 11461592 + Missense_Mutation SNP G G T rs199532199 bycluster;alternate_allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . PRB4 NM_001261399 exon3 c.C325A p.Q109K GGGACTGGTTTCC 263 10 0.04 151 2 0.0132450331 59 0 0 GXYLT1 283464 broad.mit.edu;mdanderson.org 37 12 42491294 42491294 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . GXYLT1 NM_173601 exon7 c.C1111A p.H371N CGTCATGGTAAAC 64 4 0.06 53 0 0 47 65 0 0.00 TUBA1A 7846 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 12 49579631 49579631 + Missense_Mutation SNP G G C novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001270399 exon4 c.C518G p.P173R GGCGCCGGGTAAA 219 39 0.18 161 0 0 2287 305 0.13 MMP19 4327 broad.mit.edu;bcgsc.ca 37 12 56231059 56231081 + Frame_Shift_Del DEL AGGGCTGGTTTGGCACTCCCGTA AGGGCTGGTTTGGCACTCCCGTA - novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 AGGGCTGGTTTGGCACTCCCGTA AGGGCTGGTTTGGCACTCCCGTA Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . MMP19 NM_002429 exon9 c.1266_1288del p.422_430del CAGCCGAGGGCTG 165 0 0.00 118 0 0 61 11 0 0.00 GRIP1 23426 broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 12 66838439 66838439 + Missense_Mutation SNP C C T rs369501964 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . GRIP1 NM_001178074 exon12 c.G1456A p.E486K CTTCTTCGAAGGT 194 32 0.16 149 1 0.0067114094 106 2 1 0.50 PLXNC1 10154 hgsc.bcm.edu;broad.mit.edu;mdanderson.org 37 12 94542893 94542893 + Missense_Mutation SNP T T A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_005761 exon1 c.T146A p.I49N GAGCCATCGCGGC 29 5 0.17 10 0 0 0 0 SSH1 54434 broad.mit.edu 37 12 109181808 109181809 + Frame_Shift_Ins INS - - G novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 - - Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 SSH1,NS,carcinoma,0,1 SSH1 NM_018984 exon15 c.3106_3107insC p.A1036fs CTGGGGCGGGTTT 156 4 0.03 107 0 0 144 1 26 0 0.00 NCOR2 9612 mdanderson.org 37 12 124887093 124887093 + Silent SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 NCOR2_ENST00000405201,NS,carcinoma,0,11 NCOR2_ENST00000405201 NM_006312 exon16 c.G1497A p.Q499Q CTGCTGCTGTTGT 74 5 0.07 43 1 0.023255814 0 11 26 1 0.04 IRS2 8660 mdanderson.org 37 13 110435299 110435299 + Silent SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_003749 exon1 c.G3102A p.P1034P CGGCGGCGGTGGC 14 2 0.14 19 0 0 0 0 DCUN1D2 55208 mdanderson.org 37 13 114138337 114138337 + Missense_Mutation SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001014283 exon2 c.G38A p.R13H AACTGGCGGACCT 47 3 0.06 63 0 0 9 0 0.00 MAPKBP1 23005 mdanderson.org 37 15 42114276 42114276 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001128608 exon26 c.G3017T p.S1006I GCAGCAGCTGCCT 113 5 0.04 92 0 0 26 0 0.00 RLBP1 6017 mdanderson.org 37 15 89761813 89761813 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_000326 exon4 c.C124A p.R42S TGTGGCGGGGCAG 81 3 0.04 53 0 0 0 0 MEF2A 4205 mdanderson.org 37 15 100214645 100214645 + Silent SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_005587 exon6 c.G444T p.V148V TCCAGTGACCAGC 131 5 0.04 124 0 0 52 0 0.00 MSLN 10232 mdanderson.org 37 16 815590 815590 + Silent SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_005823 exon10 c.C768T p.G256G GCTGGGCCAGCCC 39 3 0.08 27 0 0 0 0 CDH5 1003 broad.mit.edu 37 16 66437043 66437044 + Frame_Shift_Ins INS - - C novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 - - Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . CDH5 NM_001795 exon12 c.2326_2327insC p.S776fs TACGGCTCGGACC 146 7 0.05 150 0 0 111 34 0 0.00 SPATA2L 124044 mdanderson.org 37 16 89763952 89763952 + Nonsense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_152339 exon3 c.C1065A p.Y355X TGCCTGGTAGCCT 18 2 0.11 18 0 0 10 0 0.00 MPO 4353 mdanderson.org 37 17 56355261 56355261 + Silent SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_000250 exon7 c.G1131A p.L377L AAAGGGCAGCAGG 29 3 0.10 23 0 0 2 0 0.00 AXIN2 8313 mdanderson.org 37 17 63554672 63554672 + Silent SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 AXIN2,NS,carcinoma,0,1 AXIN2 NM_004655 exon2 c.C67A p.R23R GGGGCCGCGGGGC 38 3 0.08 31 0 0 0 1 22 0 0.00 UNK 85451 mdanderson.org 37 17 73812897 73812897 + Silent SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001080419 exon8 c.C1008T p.S336S GTCCAGCCCCACC 17 2 0.12 23 0 0 15 0 0.00 EVPL 2125 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca 37 17 74003793 74003794 + Frame_Shift_Del DEL AT AT - novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 AT AT Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 EVPL,NS,malignant_melanoma,0,1 EVPL NM_001988 exon22 c.5493_5494del p.1831_1832del TGTGTCATAGATC 49 15 0.31 75 0 0 155 2 0 0.00 TNRC6C 57690 mdanderson.org 37 17 76046266 76046266 + Missense_Mutation SNP G G A rs202206566 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 TNRC6C,rectum,carcinoma,0,1 TNRC6C NM_018996 exon4 c.G1123A p.V375I CCTACCGTACAGC 16 3 0.19 31 0 0 0 1 15 0 0.00 PDE6G 5148 mdanderson.org 37 17 79620321 79620321 + Silent SNP C C T rs370812916 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_002602 exon2 c.G15A p.P5P CTTGGGCGGTTCC 31 3 0.10 24 0 0 15 0 0.00 LDLRAD4 753 mdanderson.org 37 18 13387732 13387732 + Missense_Mutation SNP C C G novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_181482 exon3 c.C11G p.A4G CGGAAGCTGGTTT 27 3 0.11 38 0 0 2 0 0.00 REXO1 57455 broad.mit.edu 37 19 1827048 1827048 + Silent SNP T T G novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . REXO1 NM_020695 exon2 c.A1740C p.P580P GGAGGATGGGGCG 84 21 0.25 54 8 0.1481481481 55 12 0 0.00 DPP9 91039 mdanderson.org 37 19 4688811 4688811 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_139159 exon16 c.C1843A p.H615N GCTTGTGCAGGGG 50 3 0.06 38 0 0 67 0 0.00 PALM3 342979 broad.mit.edu 37 19 14164676 14164676 + Missense_Mutation SNP T T C novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . PALM3 NM_001145028 exon6 c.A1763G p.E588G ACTCCTTCCTCCT 130 4 0.03 124 0 0 26 228 0 0.00 UPF1 5976 mdanderson.org 37 19 18971766 18971766 + Missense_Mutation SNP G G A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_002911 exon17 c.G2432A p.G811D TCAGCGGCTCCCT 50 3 0.06 42 0 0 111 0 0.00 . 0 broad.mit.edu 37 19 20680085 20680085 + RNA DEL A A - novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 A A Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . . . . . TGTTCCAAAGGAA 6 2 0.33 8 0 0 0 0 GRIN2D 2906 mdanderson.org 37 19 48945587 48945587 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_000836 exon12 c.G2621T p.R874L GCCTGCGGCACTG 56 3 0.05 34 0 0 3 0 0.00 DHDH 27294 mdanderson.org 37 19 49438276 49438276 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 DHDH,right_lower_lobe,carcinoma,0,1 DHDH NM_014475 exon2 c.G110T p.R37L CGGCCCGCGATCT 21 2 0.10 36 0 0 0 1 8 0 0.00 ZNF525 170958 broad.mit.edu 37 19 53885254 53885254 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . ZNF525 . . . . TGACAAGGCTTAC 28 3 0.11 29 0 0 35 5 0 0.00 RASGRP3 25780 mdanderson.org 37 2 33783348 33783348 + Silent SNP G G T rs376806433 alternate_allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001139488 exon16 c.G1650T p.A550A CCGGGCGCCCTCC 45 3 0.07 67 0 0 13 0 0.00 TGFBRAP1 9392 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 2 105886112 105886112 + Missense_Mutation SNP T T C novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_004257 exon11 c.A2023G p.K675E CCAGCTTCCCGTG 40 10 0.25 35 0 0 31 9 0.29 ATRN 8455 broad.mit.edu 37 20 3451967 3451969 + In_Frame_Del DEL GCT GCT - novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 GCT GCT Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . ATRN NM_139321 exon1 c.213_215del p.71_72del GCCGCCGCTGCTG 9 3 0.33 8 0 0 118 1 0 0.00 GZF1 64412 mdanderson.org 37 20 23346327 23346327 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_022482 exon1 c.G1307T p.G436V CCTACGGCTGCAC 13 2 0.15 8 0 0 12 1 0.08 L3MBTL1 26013 mdanderson.org 37 20 42159018 42159018 + Missense_Mutation SNP G G A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_032107 exon10 c.G1085A p.G362D CTGCTGGCTGGTT 114 5 0.04 98 0 0 6 0 0.00 EEF1A2 1917 broad.mit.edu 37 20 62120282 62120282 + Missense_Mutation SNP T T G rs200931909 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 EEF1A2,bladder,carcinoma,0,5 EEF1A2 NM_001958 exon7 c.A1253C p.Y418S GGCGGGTACTGGG 74 24 0.32 46 13 0.2826086957 60 5 6 1 0.17 KRTAP10-6 386674 mdanderson.org 37 21 46011801 46011801 + Missense_Mutation SNP C C A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_198688 exon1 c.G565T p.A189S AGACCGCCTGGCA 153 5 0.03 142 0 0 0 0 ZDHHC8 29801 mdanderson.org 37 22 20131012 20131012 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_013373 exon10 c.G1859T p.R620L GCGCCCGCAACCC 21 2 0.10 16 0 0 16 0 0.00 LZTR1 8216 mdanderson.org 37 22 21348866 21348866 + Silent SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_006767 exon15 c.G1635T p.L545L TGTGCTGCTCATC 36 3 0.08 30 0 0 20 0 0.00 CELSR1 9620 mdanderson.org 37 22 46768935 46768935 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_014246 exon25 c.C7604A p.A2535D AGGATGGCAACCA 54 3 0.06 51 0 0 9 0 0.00 VHL 7428 mdanderson.org 37 3 10191524 10191524 + Nonsense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 VHL,NS,carcinoma,0,1 VHL NM_000551 exon3 c.G517T p.E173X AAGCCTGAGAATT 41 3 0.07 52 0 0 0 1 88 0 0.00 HACL1 26061 ucsc.edu;bcgsc.ca 37 3 15621444 15621444 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . HACL1 NM_012260 exon9 c.C776A p.P259Q CAGTATGGATGGT 42 4 0.10 68 0 0 33 66 0 0.00 QRICH1 54870 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 3 49094416 49094416 + Missense_Mutation SNP T T A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_198880 exon3 c.A1217T p.Y406F TTCTGGTACGTGC 105 16 0.15 131 0 0 113 34 0.30 MIR1324 100302212 bcgsc.ca 37 3 75679944 75679944 + RNA SNP C C T rs7614638 by2hit2allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . . . . . TCCTGCCCTCACT 69 14 0.20 78 3 0.0384615385 3 1 0.33 PIK3CA 5290 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 3 178921553 178921553 + Missense_Mutation SNP T T A rs121913284 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 PIK3CA_ENST00000263967,NS,adenocarcinoma,0,61 PIK3CA_ENST00000263967 NM_006218 exon5 c.T1035A p.N345K CGTGAATGTAAAT 89 26 0.29 64 0 0 0 61 18 7 0.39 SCARB2 950 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 4 77091110 77091110 + Missense_Mutation SNP G G C novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 SCARB2,NS,carcinoma,-2,1 SCARB2 NM_005506 exon8 c.C1023G p.H341Q GTAAAAGTGTGGG 89 11 0.12 172 0 0 -2 1 123 17 0.14 SDHA 6389 broad.mit.edu 37 5 228449 228449 + Splice_Site SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . SDHA NM_004168 exon6 c.770+1G>T . CACAGGGTAGGAA 52 3 0.06 51 0 0 80 0 0 CHSY3 337876 mdanderson.org 37 5 129241175 129241175 + Missense_Mutation SNP C C A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_175856 exon1 c.C653A p.P218Q AGCCCCCGCCACC 50 3 0.06 53 0 0 1 0 0.00 GRK6 2870 mdanderson.org 37 5 176863196 176863196 + Missense_Mutation SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001004106 exon12 c.C1180T p.R394W ATCAAGCGGGAGG 47 3 0.06 75 0 0 133 1 0.01 LPAL2 80350 mdanderson.org 37 6 160921922 160921922 + RNA SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . . . . . AACTCTGTCCATT 44 3 0.07 52 0 0 1 0 0.00 NOD1 10392 broad.mit.edu 37 7 30491698 30491698 + Missense_Mutation SNP G G T rs5743343 bycluster;byfrequency;byhapmap;by1000genomes;alternate_allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . NOD1 NM_006092 exon6 c.C1335A p.N445K GCGTGTGTTCCGC 117 4 0.03 79 0 0 79 10 0 0.00 H2AFV 94239 mdanderson.org 37 7 44874113 44874113 + Missense_Mutation SNP T T C rs1802437 bycluster;by2hit2allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_012412 exon5 c.A374G p.Q125R GTTTTCTGCTGTC 76 6 0.08 92 1 0.0108695652 0.001 604 0 0.00 PKD1L1 168507 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 7 47947691 47947691 + Missense_Mutation SNP G G A novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_138295 exon9 c.C1385T p.S462F ACTTGGGAGTCAG 69 9 0.13 75 0 0 2 0 0.00 GTF2IRD2P1 0 broad.mit.edu 37 7 72663998 72663998 + RNA SNP T T G rs2539034 bycluster TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . . . . . CCGGGGTCCTTGA 125 3 0.02 110 1 0.0090909091 0 0 ZNF277 11179 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca 37 7 111926968 111926969 + Frame_Shift_Ins INS - - AGTCC novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 - - Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . ZNF277 NM_021994 exon2 c.132_133insAGTCC p.E44fs GCCAGAAAGTCCA 96 13 0.14 103 0 0 46 17 0 0.00 PRSS3 5646 mdanderson.org 37 9 33794809 33794809 + Missense_Mutation SNP G G A rs201061108 TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_001197097 exon2 c.G20A p.S7N AGACAAGTGGCTT 44 4 0.09 62 0 0 0 0 SIGMAR1 10280 mdanderson.org 37 9 34635841 34635841 + Missense_Mutation SNP G G T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_005866 exon4 c.C460A p.H154N GCCCGTGTACTAC 30 3 0.10 45 0 0 55 0 0.00 FAM120A 23196 mdanderson.org 37 9 96320139 96320139 + Missense_Mutation SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_014612 exon14 c.C2515T p.R839C AAGATGCGCCAGA 33 3 0.09 27 0 0 47 0 0.00 RABEPK 10244 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca;mdanderson.org 37 9 127996190 127996190 + Silent SNP T T C novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 T T Unknown Untested Somatic . WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_005833 exon8 c.T1050C p.C350C GCTCTGTTTGGTG 192 15 0.08 208 0 0 41 4 0.10 STS 412 mdanderson.org 37 X 7171292 7171292 + Missense_Mutation SNP G G T rs377179856 alternate_allele TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 G G Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_000351 exon2 c.G67T p.A23S AGCCACGCAGCAT 39 3 0.08 59 0 0 6 0 0.00 TFE3 7030 mdanderson.org 37 X 48900701 48900701 + Missense_Mutation SNP C C T novel TCGA-XE-A9SE-01A-21D-A435-10 TCGA-XE-A9SE-10A-01D-A438-10 C C Unknown Untested Somatic Phase_I WXS none Illumina HiSeq 6a58d663-cd26-4aba-b604-263d1fd05531 7a457edc-11a8-4600-b310-4375e3d2c130 . . NM_006521 exon1 c.G52A p.G18S GAGGGCCCTCCGC 19 2 0.11 14 0 0 18 0 0.00