Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut ZXDA 7789 broad.mit.edu 37 X 57936620 57936620 + Missense_Mutation SNP G G C rs151072020 TCGA-DJ-A4UP-01A-11D-A257-08 TCGA-DJ-A4UP-10A-01D-A25A-08 Untested Somatic Phase_I WXS none Illumina GAIIx ee4bf1b6-4123-4c18-987a-f814b572a708 eaf8980b-fe88-4642-ba40-8b94e462e275 g.chrX:57936620G>C uc004dve.3 - 0 448 c.235C>G c.(235-237)Cat>Gat p.H79D NM_007156 NP_009087 P98168 ZXDA_HUMAN Homo sapiens zinc finger, X-linked, duplicated A (ZXDA), mRNA. 79 positive regulation of transcription, DNA-dependent nucleus C2H2 zinc finger domain binding|identical protein binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding breast(2)|endometrium(9)|kidney(1)|large_intestine(7)|lung(13)|ovary(2)|prostate(2)|skin(1) 37 CTAGGTTGATGGGGCCTCGGC 0.756000 3 23 0 0 1 0 0 ADAMDEC1 27299 broad.mit.edu 37 8 24250806 24250806 + Missense_Mutation SNP T T C TCGA-DJ-A4UP-01A-11D-A257-08 TCGA-DJ-A4UP-10A-01D-A25A-08 Untested Somatic Phase_I WXS none Illumina GAIIx ee4bf1b6-4123-4c18-987a-f814b572a708 eaf8980b-fe88-4642-ba40-8b94e462e275 g.chr8:24250806T>C uc003xdz.2 + 2 459 c.239T>C c.(238-240)aTg>aCg p.M80T ADAMDEC1_uc010lub.2_Missense_Mutation_p.M1T|ADAMDEC1_uc011lab.1_Missense_Mutation_p.M1T NM_014479 NP_001138744 O15204 ADEC1_HUMAN Homo sapiens ADAM-like, decysin 1 (ADAMDEC1), transcript variant 1, mRNA. 80 integrin-mediated signaling pathway|negative regulation of cell adhesion|proteolysis extracellular region|integral to membrane integrin binding|metalloendopeptidase activity|zinc ion binding NS(1)|breast(1)|large_intestine(4)|skin(2)|stomach(1) 9 Prostate(55;0.0181) Colorectal(74;0.016)|COAD - Colon adenocarcinoma(73;0.0646)|BRCA - Breast invasive adenocarcinoma(99;0.168) CAATATCAGATGATCTTAAAT 0.303000 6 53 0 0 1 0 0 DHX16 8449 broad.mit.edu 37 6 30633345 30633345 + Missense_Mutation SNP C C G TCGA-DJ-A4UP-01A-11D-A257-08 TCGA-DJ-A4UP-10A-01D-A25A-08 Untested Somatic Phase_I WXS none Illumina GAIIx ee4bf1b6-4123-4c18-987a-f814b572a708 eaf8980b-fe88-4642-ba40-8b94e462e275 g.chr6:30633345C>G uc003nqz.3 - 4 1044 c.832G>C c.(832-834)Gat>Cat p.D278H DHX16_uc011dmo.2_Missense_Mutation_p.D218H NM_003587 NP_003578 O60231 DHX16_HUMAN Homo sapiens DEAH (Asp-Glu-Ala-His) box polypeptide 16 (DHX16), transcript variant 1, mRNA. 278 RNA splicing|mRNA processing nucleus ATP binding|ATP-dependent helicase activity|RNA helicase activity|nucleic acid binding kidney(2)|ovary(2) 4 CGGGCGAGATCCCGCACTCGC 0.632000 12 58 0 0 1 0 0 ZNF74 7625 broad.mit.edu 37 22 20759722 20759722 + Silent SNP G G A TCGA-DJ-A4UP-01A-11D-A257-08 TCGA-DJ-A4UP-10A-01D-A25A-08 Untested Somatic Phase_I WXS none Illumina GAIIx ee4bf1b6-4123-4c18-987a-f814b572a708 eaf8980b-fe88-4642-ba40-8b94e462e275 g.chr22:20759722G>A uc010gsm.3 + 5 611 c.399G>A c.(397-399)ccG>ccA p.P133P ZNF74_uc002zsg.3_Silent_p.P62P|ZNF74_uc002zsh.3_Silent_p.P133P|ZNF74_uc002zsi.3_Silent_p.P62P|ZNF74_uc010gsn.3_Silent_p.P62P NM_003426 NP_003417 Q16587 ZNF74_HUMAN Homo sapiens zinc finger protein 74 (ZNF74), transcript variant 1, mRNA. 133 multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent actin cytoskeleton|nucleus DNA binding|RNA binding|zinc ion binding central_nervous_system(1)|cervix(1)|endometrium(3)|large_intestine(4)|lung(7)|ovary(1)|skin(1)|urinary_tract(1) 19 Melanoma(16;0.000465)|Ovarian(15;0.0025)|Colorectal(54;0.0221)|all_neural(72;0.219) Lung SC(17;0.0262)|all_lung(157;0.248) LUSC - Lung squamous cell carcinoma(15;0.00102)|Lung(15;0.0173) AAGAAGAACCGGCCCAGGAGC 0.627000 14 59 0 0 1 0 0 ZXDA 7789 broad.mit.edu 37 X 57936633 57936633 + Missense_Mutation SNP G G C TCGA-DJ-A4UP-01A-11D-A257-08 TCGA-DJ-A4UP-10A-01D-A25A-08 Untested Somatic Phase_I WXS none Illumina GAIIx ee4bf1b6-4123-4c18-987a-f814b572a708 eaf8980b-fe88-4642-ba40-8b94e462e275 g.chrX:57936633G>C uc004dve.3 - 0 435 c.222C>G c.(220-222)ttC>ttG p.F74L NM_007156 NP_009087 P98168 ZXDA_HUMAN Homo sapiens zinc finger, X-linked, duplicated A (ZXDA), mRNA. 74 positive regulation of transcription, DNA-dependent nucleus C2H2 zinc finger domain binding|identical protein binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding breast(2)|endometrium(9)|kidney(1)|large_intestine(7)|lung(13)|ovary(2)|prostate(2)|skin(1) 37 GCCTCGGCGCGAACAGGCTTG 0.761000 3 21 0 0 1 0 0 LIN37 55957 broad.mit.edu 37 19 36245363 36245363 + Silent SNP C C T TCGA-DJ-A4UP-01A-11D-A257-08 TCGA-DJ-A4UP-10A-01D-A25A-08 Untested Somatic Phase_I WXS none Illumina GAIIx ee4bf1b6-4123-4c18-987a-f814b572a708 eaf8980b-fe88-4642-ba40-8b94e462e275 g.chr19:36245363C>T uc021usw.1 + 8 1093 c.729C>T c.(727-729)taC>taT p.Y243Y AL137752_uc002obl.3_5'Flank NM_019104 NP_061977 Q96GY3 LIN37_HUMAN Homo sapiens lin-37 homolog (C. elegans) (LIN37), mRNA. 243 protein binding large_intestine(1)|lung(5) 6 all_lung(56;3.33e-07)|Lung NSC(56;5.02e-07)|Esophageal squamous(110;0.162) LUSC - Lung squamous cell carcinoma(66;0.0515) GAGAGATGTACGAACGACAGT 0.577000 6 25 0 0 1 0 0