Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
TP73	7161	broad.mit.edu	37	1	3624240	3624240	+	Missense_Mutation	SNP	C	C	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr1:3624240C>T	uc001akp.3	+	3	424	c.314C>T	c.(313-315)aCc>aTc	p.T105I	TP73_uc021ofb.1_Missense_Mutation_p.T105I|TP73_uc021ofc.1_Missense_Mutation_p.T105I|TP73_uc021ofd.1_Missense_Mutation_p.T105I|TP73_uc021ofe.1_Missense_Mutation_p.T105I|TP73_uc021off.1_Missense_Mutation_p.T105I|TP73_uc010nzj.2_Missense_Mutation_p.T56I|TP73_uc021ofg.1_Missense_Mutation_p.T56I|TP73_uc021ofh.1_Missense_Mutation_p.T56I|TP73_uc021ofi.1_Missense_Mutation_p.T56I|TP73_uc001akr.3_Missense_Mutation_p.T56I|TP73_uc009vlk.2_Missense_Mutation_p.T56I|TP73_uc001aks.3_Missense_Mutation_p.T56I|TP73_uc009vll.3_Missense_Mutation_p.T34I|TP73_uc010nzk.2_Missense_Mutation_p.T34I	NM_005427	NP_001191121	O15350	P73_HUMAN	Homo sapiens tumor protein p73 (TP73), transcript variant 1, mRNA.	105					DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cellular response to UV|mismatch repair|mitotic cell cycle G1/S transition DNA damage checkpoint|negative regulation of JUN kinase activity|negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|protein tetramerization|response to X-ray|response to gamma radiation	chromatin|cytosol|transcription factor complex	chromatin binding|damaged DNA binding|double-stranded DNA binding|metal ion binding|p53 binding|protein binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|transcription regulatory region DNA binding|transcription repressor activity	p.S104F(1)		breast(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|lung(8)|ovary(1)|prostate(1)	20	all_cancers(77;0.0395)|Ovarian(185;0.0634)|Lung NSC(156;0.188)|all_lung(157;0.198)	all_epithelial(116;7.42e-17)|all_lung(118;1.86e-06)|Lung NSC(185;0.000163)|Renal(390;0.00357)|Breast(487;0.00446)|Hepatocellular(190;0.0218)|Myeloproliferative disorder(586;0.0393)|Lung SC(97;0.109)|Ovarian(437;0.127)		Epithelial(90;5.57e-38)|OV - Ovarian serous cystadenocarcinoma(86;1.87e-22)|GBM - Glioblastoma multiforme(42;5.72e-16)|Colorectal(212;2.22e-05)|COAD - Colon adenocarcinoma(227;8.48e-05)|Kidney(185;0.000539)|BRCA - Breast invasive adenocarcinoma(365;0.000868)|STAD - Stomach adenocarcinoma(132;0.0072)|KIRC - Kidney renal clear cell carcinoma(229;0.00751)|Lung(427;0.226)		CCCAGCTCCACCTTCGACACC	0.672000													36	53					0	0	1	0	0
RABGAP1	23637	broad.mit.edu	37	9	125863904	125863904	+	Silent	SNP	A	A	G			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr9:125863904A>G	uc011lzh.2	+	24	3083	c.2949A>G	c.(2947-2949)aaA>aaG	p.K983K	RABGAP1_uc004bnl.4_Non-coding_Transcript|RABGAP1_uc011lzj.2_Silent_p.K322K	NM_012197	NP_036329	Q9Y3P9	RBGP1_HUMAN	Homo sapiens RAB GTPase activating protein 1 (RABGAP1), mRNA.	983					cell cycle	centrosome|cytosol|microtubule associated complex	Rab GTPase activator activity|tubulin binding			breast(3)|endometrium(3)|kidney(5)|large_intestine(8)|lung(11)|ovary(3)|prostate(4)|stomach(3)|upper_aerodigestive_tract(1)	41						GGCGTGTAAAAGGCATAAGCT	0.448000													3	68					0	0	1	0	0
PNN	5411	broad.mit.edu	37	14	39650419	39650419	+	Silent	SNP	T	T	C			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr14:39650419T>C	uc001wuw.4	+	8	1603	c.1506T>C	c.(1504-1506)ccT>ccC	p.P502P		NM_002687	NP_002678	Q9H307	PININ_HUMAN	Homo sapiens pinin, desmosome associated protein (PNN), mRNA.	502	Gln-rich.				cell adhesion|regulation of transcription, DNA-dependent|transcription, DNA-dependent	catalytic step 2 spliceosome|desmosome|intermediate filament|nuclear speck	DNA binding|protein binding|structural molecule activity			breast(2)|endometrium(5)|kidney(1)|large_intestine(6)|lung(9)|ovary(1)|skin(2)|stomach(1)	27	Hepatocellular(127;0.213)		LUAD - Lung adenocarcinoma(48;0.000565)|Lung(238;0.000711)	GBM - Glioblastoma multiforme(112;0.0119)		CCTCTCAGCCTGAGGATTTGT	0.517000													3	131					0	0	1	0	0
ZNF230	7773	broad.mit.edu	37	19	44515136	44515136	+	Silent	SNP	A	A	G			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr19:44515136A>G	uc002oyb.1	+	4	1196	c.945A>G	c.(943-945)aaA>aaG	p.K315K		NM_006300	NP_006291	Q9UIE0	ZN230_HUMAN	Homo sapiens zinc finger protein 230 (ZNF230), mRNA.	315					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(1)|endometrium(2)|large_intestine(2)|lung(10)|skin(1)|stomach(3)|urinary_tract(2)	22		Prostate(69;0.0352)				AGTGTGGAAAAGGCTTCACTG	0.423000													3	206					0	0	1	0	0
TRIM13	10206	broad.mit.edu	37	13	50586828	50586828	+	Missense_Mutation	SNP	A	A	G			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr13:50586828A>G	uc001vdp.1	+	3	1179	c.761A>G	c.(760-762)cAg>cGg	p.Q254R	DLEU2_uc001vdn.1_Intron|DLEU2_uc001vdo.1_Intron|KCNRG_uc001vdt.3_5'Flank|KCNRG_uc001vdu.3_5'Flank|TRIM13_uc001vdq.1_Missense_Mutation_p.Q251R|TRIM13_uc001vdr.1_Missense_Mutation_p.Q251R|TRIM13_uc001vds.1_Missense_Mutation_p.Q251R|TRIM13_uc021rjq.1_Missense_Mutation_p.Q251R	NM_001007278	NP_998755	O60858	TRI13_HUMAN	Homo sapiens tripartite motif containing 13 (TRIM13), transcript variant 4, mRNA.	251					ER-associated protein catabolic process|anatomical structure morphogenesis|positive regulation of I-kappaB kinase/NF-kappaB cascade|protein autoubiquitination	cytoplasm|endoplasmic reticulum membrane|integral to membrane	protein binding|signal transducer activity|ubiquitin-protein ligase activity|zinc ion binding			large_intestine(5)|lung(2)|ovary(2)|upper_aerodigestive_tract(1)	10		Acute lymphoblastic leukemia(7;3.41e-06)|Lung NSC(96;3.08e-05)|Breast(56;9.7e-05)|Prostate(109;0.00174)|Hepatocellular(98;0.0207)|Myeloproliferative disorder(33;0.163)|Lung SC(185;0.187)|all_neural(104;0.19)		GBM - Glioblastoma multiforme(99;1.53e-10)|COAD - Colon adenocarcinoma(199;0.205)		TTTCTGCAACAGATGCAGGAG	0.413000													6	127					0	0	1	0	0
NOX5	79400	broad.mit.edu	37	15	69349008	69349008	+	Missense_Mutation	SNP	G	G	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr15:69349008G>T	uc002ars.2	+	15	2311	c.2270G>T	c.(2269-2271)gGc>gTc	p.G757V	MIR548H4_uc021spl.1_Intron|NOX5_uc002arq.2_Missense_Mutation_p.G711V|NOX5_uc002arp.2_Missense_Mutation_p.G739V|NOX5_uc010bid.2_Missense_Mutation_p.G722V|NOX5_uc010bie.2_Missense_Mutation_p.G557V|NOX5_uc002arr.2_Missense_Mutation_p.G729V|NOX5_uc010bif.2_Non-coding_Transcript	NM_024505	NP_078781	Q96PH1	NOX5_HUMAN	Homo sapiens NADPH oxidase, EF-hand calcium binding domain 5 (NOX5), transcript variant 1, mRNA.	757					angiogenesis|cytokine secretion|cytokinesis|electron transport chain|endothelial cell proliferation|induction of apoptosis|positive regulation of reactive oxygen species metabolic process|regulation of fusion of sperm to egg plasma membrane|regulation of proton transport|superoxide anion generation	endoplasmic reticulum|integral to membrane	NADP binding|calcium ion binding|electron carrier activity|flavin adenine dinucleotide binding|heme binding|hydrogen ion channel activity|superoxide-generating NADPH oxidase activity			breast(3)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|liver(2)|lung(18)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	35						GAGAAGTTCGGCTTCAGATTT	0.517000													48	36					0	0	1	0	0
PPP2R1B	5519	broad.mit.edu	37	11	111625705	111625705	+	Splice_Site	SNP	T	T	C			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr11:111625705T>C	uc001plw.1	-	7	1042	c.958_splice	c.e7+1	p.E320_splice	PPP2R1B_uc010rwi.1_Splice_Site_p.E256_splice|PPP2R1B_uc001plx.1_Splice_Site_p.E320_splice|PPP2R1B_uc010rwk.1_Splice_Site_p.E320_splice|PPP2R1B_uc010rwl.1_Splice_Site_p.E193_splice|PPP2R1B_uc010rwj.1_Splice_Site_p.E159_splice	NM_181699	NP_859050	P30154	2AAB_HUMAN	Homo sapiens protein phosphatase 2, regulatory subunit A, beta (PPP2R1B), transcript variant 2, mRNA.	320							protein binding			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(2)|liver(1)|lung(10)|prostate(1)|urinary_tract(2)	22		all_cancers(61;2.34e-15)|all_epithelial(67;1.72e-09)|Melanoma(852;1.91e-06)|all_hematologic(158;0.000405)|Acute lymphoblastic leukemia(157;0.000967)|Breast(348;0.0112)|all_neural(223;0.0281)|Medulloblastoma(222;0.0425)		BRCA - Breast invasive adenocarcinoma(274;1.13e-06)|Epithelial(105;2.36e-06)|all cancers(92;3.78e-05)|OV - Ovarian serous cystadenocarcinoma(223;0.0761)		CTCCTTAACCTTTTACTTTGT	0.383000													3	80					0	0	1	0	0
GZMM	3004	broad.mit.edu	37	19	547312	547312	+	Missense_Mutation	SNP	C	C	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr19:547312C>T	uc002low.1	+	1	133	c.88C>T	c.(88-90)Cgg>Tgg	p.R30W		NM_005317	NP_005308	P51124	GRAM_HUMAN	Homo sapiens granzyme M (lymphocyte met-ase 1) (GZMM), mRNA.	30	Peptidase S1.				apoptosis|cytolysis|innate immune response|proteolysis	extracellular region	serine-type endopeptidase activity			endometrium(1)|large_intestine(1)|prostate(1)	3		all_cancers(10;1.94e-35)|all_epithelial(18;5.94e-23)|Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;3.55e-06)|all_lung(49;5.41e-06)|Breast(49;4.08e-05)|Hepatocellular(1079;0.137)|Renal(1328;0.228)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CATCGGGGGCCGGGAGGTGAT	0.647000													78	84					0	0	1	0	0
ZZZ3	26009	broad.mit.edu	37	1	78097775	78097775	+	Missense_Mutation	SNP	T	T	A			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr1:78097775T>A	uc001dhq.3	-	4	1741	c.1265A>T	c.(1264-1266)aAt>aTt	p.N422I	ZZZ3_uc001dhr.3_Intron|ZZZ3_uc009wbz.1_Missense_Mutation_p.N422I|ZZZ3_uc001dhp.3_Missense_Mutation_p.N422I	NM_015534	NP_056349	Q8IYH5	ZZZ3_HUMAN	Homo sapiens zinc finger, ZZ-type containing 3 (ZZZ3), mRNA.	422					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|endometrium(2)|kidney(2)|large_intestine(8)|lung(17)|ovary(4)|prostate(1)|stomach(1)|urinary_tract(2)	39						TTGACTTACATTATCACTAAC	0.343000													4	86					0	0	1	0	0
IRX6	79190	broad.mit.edu	37	16	55363139	55363139	+	Silent	SNP	C	C	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr16:55363139C>T	uc002ehy.3	+	4	1782	c.1249C>T	c.(1249-1251)Ctg>Ttg	p.L417L	IRX6_uc002ehx.3_Silent_p.L417L	NM_024335	NP_077311	P78412	IRX6_HUMAN	Homo sapiens iroquois homeobox 6 (IRX6), mRNA.	417						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(2)|central_nervous_system(5)|endometrium(3)|kidney(2)|large_intestine(6)|liver(2)|lung(10)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	33						CAAGTTTGCCCTGCAGGGACT	0.642000													8	140					0	0	1	0	0
ZNF341	84905	broad.mit.edu	37	20	32341114	32341114	+	Missense_Mutation	SNP	G	G	A			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr20:32341114G>A	uc002wzy.3	+	4	646	c.626G>A	c.(625-627)cGt>cAt	p.R209H	ZNF341_uc002wzx.3_Missense_Mutation_p.R209H|ZNF341_uc010geq.3_Missense_Mutation_p.R119H|ZNF341_uc010ger.3_Non-coding_Transcript	NM_032819	NP_116208	Q9BYN7	ZN341_HUMAN	Homo sapiens zinc finger protein 341 (ZNF341), mRNA.	209					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(1)|central_nervous_system(2)|endometrium(3)|kidney(4)|large_intestine(3)|lung(8)|ovary(2)|prostate(3)|skin(1)|urinary_tract(3)	31						CCCCCTGGGCGTCCCAACCCT	0.697000													13	10					0	0	1	0	0
GABRQ	55879	broad.mit.edu	37	X	151818902	151818902	+	Missense_Mutation	SNP	C	C	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chrX:151818902C>T	uc004ffp.1	+	6	780	c.760C>T	c.(760-762)Cgc>Tgc	p.R254C		NM_018558	NP_061028	Q9UN88	GBRT_HUMAN	Homo sapiens gamma-aminobutyric acid (GABA) receptor, theta (GABRQ), mRNA.	254						cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	GABA-A receptor activity|chloride channel activity|extracellular ligand-gated ion channel activity|neurotransmitter transporter activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(4)|large_intestine(9)|lung(25)|ovary(3)|pancreas(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	52	Acute lymphoblastic leukemia(192;6.56e-05)					TTCCTACATACGCCTGATACT	0.522000													12	487					0	0	1	0	0
CR2	1380	broad.mit.edu	37	1	207643143	207643143	+	Silent	SNP	G	G	A			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr1:207643143G>A	uc001hfv.3	+	5	1040	c.921G>A	c.(919-921)ccG>ccA	p.P307P	CR2_uc001hfw.3_Silent_p.P307P|CR2_uc009xch.3_Silent_p.P307P|CR2_uc009xci.1_5'Flank	NM_001006658	NP_001006659	P20023	CR2_HUMAN	Homo sapiens complement component (3d/Epstein Barr virus) receptor 2 (CR2), transcript variant 1, mRNA.	307	Sushi 5.				complement activation, classical pathway|innate immune response	integral to membrane|plasma membrane	complement receptor activity|protein homodimerization activity			NS(2)|breast(3)|endometrium(4)|kidney(3)|large_intestine(12)|lung(26)|ovary(1)|pancreas(1)|prostate(1)|skin(12)|upper_aerodigestive_tract(3)|urinary_tract(1)	69						CTTGTGACCCGGACCCAGAGG	0.488000													4	98					0	0	1	0	0
LDB3	11155	broad.mit.edu	37	10	88441198	88441198	+	Silent	SNP	C	C	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr10:88441198C>T	uc010qmm.2	+	4	472	c.327C>T	c.(325-327)ccC>ccT	p.P109P	LDB3_uc010qml.1_Silent_p.P109P|LDB3_uc009xsz.3_Intron|LDB3_uc001kdu.3_Intron|LDB3_uc001kdv.3_Silent_p.P109P|LDB3_uc001kdr.3_Intron|LDB3_uc001kdt.3_Non-coding_Transcript|LDB3_uc009xsy.3_Silent_p.P109P|LDB3_uc001kds.3_Silent_p.P109P	NM_001171610	NP_001165081	O75112	LDB3_HUMAN	Homo sapiens LIM domain binding 3 (LDB3), transcript variant 5, mRNA.	109						cytoskeleton|perinuclear region of cytoplasm|pseudopodium	zinc ion binding			breast(1)|endometrium(3)|kidney(2)|large_intestine(5)|lung(9)|ovary(3)|prostate(1)|soft_tissue(1)	25						GCCAGGACCCCGCTCTGGACA	0.677000													4	183					0	0	1	0	0
ZNF462	58499	broad.mit.edu	37	9	109687520	109687520	+	Missense_Mutation	SNP	T	T	C			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr9:109687520T>C	uc004bcz.3	+	2	1616	c.1327T>C	c.(1327-1329)Ttt>Ctt	p.F443L	MIR548Q_uc022bli.1_Intron|ZNF462_uc010mto.3_Missense_Mutation_p.F291L|ZNF462_uc004bda.3_Missense_Mutation_p.F291L	NM_021224	NP_067047	Q96JM2	ZN462_HUMAN	Homo sapiens zinc finger protein 462 (ZNF462), mRNA.	443					transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(2)|autonomic_ganglia(2)|breast(5)|central_nervous_system(4)|cervix(1)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(17)|large_intestine(20)|lung(32)|ovary(5)|prostate(6)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	119						CCAGTGCCCCTTTTGTCCTTT	0.463000													3	126					0	0	1	0	0
FAM35A	54537	broad.mit.edu	37	10	88911225	88911225	+	Missense_Mutation	SNP	A	A	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr10:88911225A>T	uc001kei.4	+	2	228	c.114A>T	c.(112-114)aaA>aaT	p.K38N		NM_019054	NP_061927	Q86V20	FA35A_HUMAN	Homo sapiens family with sequence similarity 35, member A (FAM35A), mRNA.	38										endometrium(2)|kidney(2)|large_intestine(5)|lung(1)|ovary(2)|prostate(2)|skin(2)	16						CCTGGAAAAAAATTCAGCTTT	0.373000													21	16					0	0	1	0	0
MYCBP2	23077	broad.mit.edu	37	13	77740543	77740543	+	Missense_Mutation	SNP	A	A	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr13:77740543A>T	uc021rks.1	-	40	6528	c.6261T>A	c.(6259-6261)caT>caA	p.H2087Q	MYCBP2_uc010aev.3_Missense_Mutation_p.H1453Q	NM_015057	NP_055872	O75592	MYCB2_HUMAN	Homo sapiens MYC binding protein 2 (MYCBP2), mRNA.	2049					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	ligase activity|protein binding|zinc ion binding			NS(1)|autonomic_ganglia(1)|breast(8)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(17)|lung(51)|ovary(5)|pancreas(2)|prostate(5)|skin(7)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	118		Breast(118;0.212)|Acute lymphoblastic leukemia(28;0.22)		GBM - Glioblastoma multiforme(99;0.109)		TAAGATTTTCATGAACAGATG	0.383000													5	72					0	0	1	0	0
ZBTB32	27033	broad.mit.edu	37	19	36206734	36206734	+	Splice_Site	SNP	T	T	C			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr19:36206734T>C	uc002oay.3	+	3	1165	c.955_splice	c.e3+2	p.G319_splice	ZBTB32_uc002oaz.3_Intron|MLL2_uc021usu.1_5'Flank|MLL2_uc021usv.1_5'Flank	NM_014383	NP_055198	Q9Y2Y4	ZBT32_HUMAN	Homo sapiens zinc finger and BTB domain containing 32 (ZBTB32), mRNA.	319					DNA repair|negative regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter	nucleoplasm	DNA binding|protein binding|transcription corepressor activity|zinc ion binding			large_intestine(5)|lung(1)|ovary(1)|prostate(2)|skin(2)|stomach(1)|urinary_tract(2)	14	all_lung(56;2.22e-07)|Lung NSC(56;3.47e-07)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0515)			CTACCCCAGGTAAGCCCCTCG	0.617000													3	84					0	0	1	0	0
HIF3A	64344	broad.mit.edu	37	19	46815428	46815428	+	Missense_Mutation	SNP	G	G	T			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr19:46815428G>T	uc002peh.3	+	6	812	c.781G>T	c.(781-783)Gtg>Ttg	p.V261L	HIF3A_uc002pef.2_Missense_Mutation_p.V261L|HIF3A_uc002peg.4_Missense_Mutation_p.V261L|HIF3A_uc010xxx.2_Non-coding_Transcript|HIF3A_uc021uwf.1_Missense_Mutation_p.V205L|HIF3A_uc002pej.2_Missense_Mutation_p.V192L|HIF3A_uc010xxy.2_Missense_Mutation_p.V192L|HIF3A_uc002pel.3_Missense_Mutation_p.V259L|HIF3A_uc010xxz.2_Missense_Mutation_p.V210L	NM_152795	NP_690008	Q9Y2N7	HIF3A_HUMAN	Homo sapiens hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 3, mRNA.	261	PAS 2.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|signal transducer activity	p.A260T(1)|p.G261D(1)		breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(7)|lung(14)|prostate(1)|skin(6)|upper_aerodigestive_tract(1)	33		Ovarian(192;0.00965)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00204)|all cancers(93;0.0107)|GBM - Glioblastoma multiforme(486;0.0489)|Epithelial(262;0.136)		GATTGCAGAAGTGGCTGGCTA	0.592000													9	241					0	0	1	0	0
SLA	6503	broad.mit.edu	37	8	134072405	134072408	+	Frame_Shift_Del	DEL	TTTC	TTTC	-			TCGA-ET-A3DV-01A-12D-A202-08	TCGA-ET-A3DV-11A-11D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5deeaa45-4c1b-4ab2-a487-93c548838f68	bba5ac91-59b6-4cae-9199-e31d43571f57	g.chr8:134072405_134072408delTTTC	uc011ljd.2	-	0	196_199	c.118_121delGAAA	c.(118-123)gaaatgfs	p.E40fs	TG_uc003ytw.3_Intron|TG_uc010mdw.3_Intron|TG_uc011ljb.2_Intron|TG_uc011ljc.2_Intron|SLA_uc003ytz.3_Start_Codon_Del|SLA_uc011lje.2_Frame_Shift_Del_p.E17fs|SLA_uc011ljf.2_Intron|SLA_uc011ljg.2_Frame_Shift_Del_p.E17fs|SLA_uc010mdy.1_Start_Codon_Del|SLA_uc010mdz.1_Start_Codon_Del|SLA_uc010mea.2_Non-coding_Transcript	NM_006748	NP_006739	Q13239	SLAP1_HUMAN	Homo sapiens Src-like-adaptor (SLA), transcript variant 3, mRNA.	0	SH3.					endosome	SH3/SH2 adaptor activity	p.P40H(1)		central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|liver(1)|lung(6)|prostate(1)|skin(1)	17	all_epithelial(106;3.51e-21)|Lung NSC(106;4.24e-06)|Ovarian(258;0.00438)|Acute lymphoblastic leukemia(118;0.155)	Myeloproliferative disorder(644;0.00878)|Acute lymphoblastic leukemia(644;0.0279)|Breast(495;0.037)	BRCA - Breast invasive adenocarcinoma(115;0.000701)			CTGTTTCCCATTTCTTTCTTTTTC	0.578													55	83	---	---	---	---