Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PLEC	5339	broad.mit.edu	37	8	145007232	145007232	+	Missense_Mutation	SNP	T	T	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr8:145007232T>A	ENST00000322810.4	-	14	2046	c.1877A>T	c.(1876-1878)aAc>aTc	p.N626I	PLEC_ENST00000527096.1_Missense_Mutation_p.N512I|PLEC_ENST00000356346.3_Missense_Mutation_p.N475I|PLEC_ENST00000357649.2_Missense_Mutation_p.N493I|PLEC_ENST00000436759.2_Missense_Mutation_p.N516I|PLEC_ENST00000398774.2_Missense_Mutation_p.N457I|PLEC_ENST00000354958.2_Missense_Mutation_p.N467I|PLEC_ENST00000354589.3_Missense_Mutation_p.N489I|PLEC_ENST00000345136.3_Missense_Mutation_p.N489I	NM_201380.2	NP_958782.1	Q15149	PLEC_HUMAN	plectin	626	Globular 1.				cellular component disassembly involved in apoptosis|hemidesmosome assembly	cytosol|focal adhesion|hemidesmosome|intermediate filament cytoskeleton|sarcolemma	actin binding|structural constituent of muscle			NS(1)|breast(3)|central_nervous_system(4)|cervix(7)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(8)|lung(57)|ovary(4)|pancreas(2)|prostate(11)|skin(9)|stomach(2)|upper_aerodigestive_tract(10)	137						CAGCCGTAGGTTGTACTCGGT	0.672000													6	5					0	0	1	0	0
LRP10	26020	broad.mit.edu	37	14	23345043	23345043	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr14:23345043C>T	ENST00000359591.4	+	5	1577	c.886C>T	c.(886-888)Cgt>Tgt	p.R296C	LRP10_ENST00000546834.1_Missense_Mutation_p.R296C	NM_014045.3	NP_054764.2	Q7Z4F1	LRP10_HUMAN	low density lipoprotein receptor-related protein 10	296	CUB 2.				endocytosis	coated pit|integral to membrane				central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|liver(2)|lung(7)|ovary(2)|prostate(2)|skin(5)|stomach(1)|urinary_tract(2)	32	all_cancers(95;4.69e-05)			GBM - Glioblastoma multiforme(265;0.00549)		GAGCAATGGTCGTGGCTTCAA	0.582000													23	68					0	0	1	0	0
NBPF10	100132406	broad.mit.edu	37	1	145302714	145302714	+	Silent	SNP	A	A	G	rs9424867		TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr1:145302714A>G	ENST00000342960.5	+	8	1187	c.1152A>G	c.(1150-1152)ttA>ttG	p.L384L	NBPF10_ENST00000369338.1_Silent_p.L113L|NBPF10_ENST00000369339.2_Silent_p.L113L|RP11-458D21.5_ENST00000468030.1_3'UTR	NM_001039703.4	NP_001034792.4	A6NDV3	A6NDV3_HUMAN	neuroblastoma breakpoint family, member 10	384								p.L113L(3)|p.L384L(3)		NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		AGGAGAAGTTACGGGAAGGGA	0.527000													5	71					0	0	1	0	0
KCNC3	3748	broad.mit.edu	37	19	50823987	50823987	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr19:50823987G>A	ENST00000391818.2	-	2	101	c.43C>T	c.(43-45)Cag>Tag	p.Q15*	KCNC3_ENST00000376959.2_Missense_Mutation_p.P678L|KCNC3_ENST00000477616.1_Missense_Mutation_p.P678L|KCNC3_ENST00000474951.1_5'UTR			Q14003	KCNC3_HUMAN	potassium voltage-gated channel, Shaw-related subfamily, member 3	29					cell death	voltage-gated potassium channel complex	voltage-gated potassium channel activity			endometrium(2)|large_intestine(4)|lung(5)|pancreas(1)|skin(1)	13		all_neural(266;0.057)|Ovarian(192;0.208)		OV - Ovarian serous cystadenocarcinoma(262;0.00283)|GBM - Glioblastoma multiforme(134;0.0181)		GTCAATGGCTGGGCAGTCCTC	0.642000													5	39					0	0	1	0	0
FRG1B	0	broad.mit.edu	37	20	29625875	29625875	+	Missense_Mutation	SNP	T	T	C	rs143761036	by1000genomes	TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr20:29625875T>C	ENST00000278882.3	+	5	499	c.119T>C	c.(118-120)aTc>aCc	p.I40T	FRG1B_ENST00000439954.2_Missense_Mutation_p.I45T|FRG1B_ENST00000358464.4_Missense_Mutation_p.I40T														p.I40T(4)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						ATGTACAGAATCGCCCTGAAA	0.358000													6	117					0	0	1	0	0
CDK5RAP2	55755	broad.mit.edu	37	9	123210305	123210305	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr9:123210305G>A	ENST00000349780.4	-	22	3072	c.2893C>T	c.(2893-2895)Cag>Tag	p.Q965*	CDK5RAP2_ENST00000360822.3_Nonsense_Mutation_p.Q933*|CDK5RAP2_ENST00000360190.4_Nonsense_Mutation_p.Q965*|CDK5RAP2_ENST00000359309.3_Nonsense_Mutation_p.Q965*	NM_018249.4	NP_060719.4	Q96SN8	CK5P2_HUMAN	CDK5 regulatory subunit associated protein 2	965	Interaction with MAPRE1.				brain development|centrosome organization|chromosome segregation|G2/M transition of mitotic cell cycle|microtubule bundle formation|negative regulation of centriole replication|positive regulation of transcription, DNA-dependent|regulation of neuron differentiation|regulation of spindle checkpoint	cytosol|Golgi apparatus|microtubule|pericentriolar material|perinuclear region of cytoplasm|spindle pole	calmodulin binding|microtubule binding|neuronal Cdc2-like kinase binding|transcription regulatory region DNA binding			breast(6)|central_nervous_system(1)|endometrium(3)|kidney(4)|large_intestine(12)|lung(21)|ovary(2)|prostate(2)|skin(6)|urinary_tract(1)	58						ATCTGGCTCTGCAGCTGCGTC	0.498000													9	109					0	0	1	0	0
PCDH1	5097	broad.mit.edu	37	5	141244422	141244422	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr5:141244422G>A	ENST00000287008.3	-	3	1621	c.1474C>T	c.(1474-1476)Ctc>Ttc	p.L492F	PCDH1_ENST00000536585.1_Missense_Mutation_p.L470F|PCDH1_ENST00000511044.1_5'UTR|PCDH1_ENST00000503492.1_Intron|PCDH1_ENST00000456271.1_Missense_Mutation_p.L480F|PCDH1_ENST00000394536.3_Missense_Mutation_p.L492F	NM_032420.2	NP_115796.2	Q08174	PCDH1_HUMAN	protocadherin 1	492	Cadherin 4.				cell-cell signaling|homophilic cell adhesion|nervous system development	cell-cell junction|integral to plasma membrane	calcium ion binding			breast(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(4)|lung(20)|ovary(5)|skin(3)|upper_aerodigestive_tract(1)	51		Lung NSC(810;0.027)|all_lung(500;0.0321)|all_hematologic(541;0.0433)|Prostate(461;0.0453)|Breast(839;0.128)|Lung SC(612;0.238)	KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)	GBM - Glioblastoma multiforme(465;1.06e-05)		TGCACCTTGAGGGAGTTAGTG	0.542000													19	126					0	0	1	0	0
PRCP	5547	broad.mit.edu	37	11	82611440	82611440	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr11:82611440C>T	ENST00000313010.3	-	1	199	c.5G>A	c.(4-6)gGc>gAc	p.G2D	PRCP_ENST00000535099.1_Intron|PRCP_ENST00000393399.2_Missense_Mutation_p.G2D	NM_005040.2	NP_005031.1	P42785	PCP_HUMAN	prolylcarboxypeptidase (angiotensinase C)	2					blood coagulation, intrinsic pathway|proteolysis	lysosome|plasma membrane	protein binding|serine-type carboxypeptidase activity			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(7)|prostate(1)|skin(2)|urinary_tract(1)	17						GGCTCGGCGGCCCATGGCTCA	0.687000													9	30					0	0	1	0	0
DHX9	1660	broad.mit.edu	37	1	182812436	182812436	+	Missense_Mutation	SNP	T	T	G			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr1:182812436T>G	ENST00000367549.3	+	3	229	c.119T>G	c.(118-120)gTg>gGg	p.V40G		NM_001357.4	NP_001348.2	Q08211	DHX9_HUMAN	DEAH (Asp-Glu-Ala-His) box helicase 9	40	DRBM 1.|Interaction with CREBBP.				CRD-mediated mRNA stabilization|nuclear mRNA splicing, via spliceosome	centrosome|CRD-mediated mRNA stability complex|nucleolus|nucleoplasm|ribonucleoprotein complex	ATP binding|ATP-dependent DNA helicase activity|ATP-dependent RNA helicase activity|DNA binding|double-stranded RNA binding|protein binding	p.V40G(8)		NS(1)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(10)|kidney(3)|large_intestine(7)|liver(1)|lung(19)|ovary(2)|prostate(1)|skin(1)|urinary_tract(2)	49						AAGGTTCAGGTGGAAGGTTAT	0.333000													11	40					0	0	1	0	0
PLSCR4	57088	broad.mit.edu	37	3	145914466	145914466	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr3:145914466G>A	ENST00000354952.2	-	7	979	c.739C>T	c.(739-741)Cgt>Tgt	p.R247C	PLSCR4_ENST00000493382.1_Missense_Mutation_p.R247C|PLSCR4_ENST00000433593.2_Missense_Mutation_p.R142C|PLSCR4_ENST00000383083.2_Missense_Mutation_p.R157C|PLSCR4_ENST00000446574.2_Missense_Mutation_p.R247C	NM_020353.2	NP_065086.2	Q9NRQ2	PLS4_HUMAN	phospholipid scramblase 4	247					blood coagulation|phospholipid scrambling	integral to membrane	calcium ion binding|phospholipid scramblase activity|SH3 domain binding			kidney(1)|large_intestine(6)|lung(9)|urinary_tract(1)	17						CATGGCCCACGAACTCTCATC	0.423000													43	75					0	0	1	0	0
ESYT3	83850	broad.mit.edu	37	3	138191501	138191501	+	Silent	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr3:138191501C>T	ENST00000389567.4	+	18	2223	c.2037C>T	c.(2035-2037)atC>atT	p.I679I		NM_031913.3	NP_114119.2	A0FGR9	ESYT3_HUMAN	extended synaptotagmin-like protein 3	679						integral to membrane|plasma membrane				breast(1)|endometrium(5)|large_intestine(7)|lung(9)|prostate(1)|skin(1)|urinary_tract(1)	25						GTGAGCCCATCGGGGAGAAGA	0.597000													30	85					0	0	1	0	0
DSPP	1834	broad.mit.edu	37	4	88534400	88534400	+	Silent	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr4:88534400C>T	ENST00000399271.1	+	4	1182	c.1062C>T	c.(1060-1062)cgC>cgT	p.R354R	RP11-742B18.1_ENST00000506480.1_RNA|DSPP_ENST00000282478.7_Silent_p.R354R	NM_014208.3	NP_055023.2	Q9NZW4	DSPP_HUMAN	dentin sialophosphoprotein	354					biomineral tissue development|ossification|skeletal system development	proteinaceous extracellular matrix	calcium ion binding|collagen binding|extracellular matrix structural constituent			breast(2)|central_nervous_system(1)|endometrium(9)|kidney(4)|large_intestine(8)|lung(13)|ovary(1)|skin(3)|stomach(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	47		Hepatocellular(203;0.114)|all_hematologic(202;0.236)		OV - Ovarian serous cystadenocarcinoma(123;0.000508)		AAAGCAAACGCGTAGAAAATA	0.418000													28	39					0	0	1	0	0
ZNF644	84146	broad.mit.edu	37	1	91403245	91403245	+	Missense_Mutation	SNP	C	C	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr1:91403245C>A	ENST00000370440.1	-	4	3702	c.3485G>T	c.(3484-3486)aGt>aTt	p.S1162I	ZNF644_ENST00000347275.5_Intron|ZNF644_ENST00000361321.5_Intron|ZNF644_ENST00000337393.5_Missense_Mutation_p.S1162I|ZNF644_ENST00000467231.1_Intron			Q9H582	ZN644_HUMAN	zinc finger protein 644	1162					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(4)|endometrium(2)|large_intestine(10)|lung(21)|ovary(2)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(2)	47		all_lung(203;0.00206)|Lung NSC(277;0.0519)|Lung SC(238;0.101)		all cancers(265;0.00102)|Epithelial(280;0.00766)|KIRC - Kidney renal clear cell carcinoma(1967;0.147)|OV - Ovarian serous cystadenocarcinoma(397;0.173)		CTTTTTCCCACTGGGCAGTTC	0.373000													12	149					0.000978159	0.000999423	1	1	0
DDC	1644	broad.mit.edu	37	7	50530960	50530960	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr7:50530960G>A	ENST00000444124.2	-	14	1612	c.1412C>T	c.(1411-1413)gCg>gTg	p.A471V	DDC_ENST00000426377.1_Missense_Mutation_p.A393V|DDC_ENST00000431062.1_Missense_Mutation_p.A378V|DDC_ENST00000357936.5_Missense_Mutation_p.A471V	NM_001082971.1	NP_001076440.1	P20711	DDC_HUMAN	dopa decarboxylase (aromatic L-amino acid decarboxylase)	471					cellular amino acid metabolic process|hormone biosynthetic process|neurotransmitter secretion	cytosol	aromatic-L-amino-acid decarboxylase activity|protein binding|pyridoxal phosphate binding			breast(1)|endometrium(4)|kidney(3)|large_intestine(2)|lung(23)|ovary(4)|skin(2)|stomach(1)	40	Glioma(55;0.08)|all_neural(89;0.245)				Amantadine(DB00915)|Carbidopa(DB00190)|Flupenthixol(DB00875)|L-Tryptophan(DB00150)|Levodopa(DB01235)|Pimozide(DB01100)|Pyridoxal Phosphate(DB00114)|Remoxipride(DB00409)	CACGTCGGCCGCCAGCTCTTT	0.597000													4	21					0	0	1	0	0
ADD3	120	broad.mit.edu	37	10	111860594	111860594	+	Silent	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr10:111860594C>T	ENST00000277900.8	+	2	548	c.183C>T	c.(181-183)atC>atT	p.I61I	ADD3_ENST00000356080.4_Silent_p.I61I|ADD3_ENST00000360162.3_Silent_p.I61I|ADD3_ENST00000497125.1_3'UTR	NM_001121.2	NP_001112.2	Q9UEY8	ADDG_HUMAN	adducin 3 (gamma)	61						cytoskeleton	actin binding|calmodulin binding|metal ion binding|structural constituent of cytoskeleton			central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(3)|large_intestine(4)|lung(9)|ovary(2)|pancreas(1)|prostate(1)|skin(3)	29		Breast(234;0.052)|Lung NSC(174;0.223)		Epithelial(162;4.15e-05)|all cancers(201;0.000587)|BRCA - Breast invasive adenocarcinoma(275;0.0742)		TTACTCAGATCCTGCAAAGTC	0.398000													9	51					0	0	1	0	0
HRCT1	646962	broad.mit.edu	37	9	35906559	35906559	+	Missense_Mutation	SNP	A	A	C			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr9:35906559A>C	ENST00000354323.2	+	1	371	c.275A>C	c.(274-276)cAc>cCc	p.H92P		NM_001039792.1	NP_001034881.1	Q6UXD1	HRCT1_HUMAN	histidine rich carboxyl terminus 1	92	His-rich.					integral to membrane		p.H92P(1)		NS(1)|haematopoietic_and_lymphoid_tissue(1)|lung(1)|prostate(1)	4						caccaccaccacccccgccac	0.682000													6	9					0	0	1	0	0
TECR	9524	broad.mit.edu	37	19	14674833	14674833	+	Missense_Mutation	SNP	C	C	G			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr19:14674833C>G	ENST00000436007.2	+	7	476	c.352C>G	c.(352-354)Ctg>Gtg	p.L118V	TECR_ENST00000600083.1_5'UTR|TECR_ENST00000215567.5_Missense_Mutation_p.L103V|TECR_ENST00000596073.1_5'UTR			Q9NZ01	TECR_HUMAN	trans-2,3-enoyl-CoA reductase	103					fatty acid elongation|long-chain fatty-acyl-CoA biosynthetic process|triglyceride biosynthetic process|very long-chain fatty acid biosynthetic process	integral to endoplasmic reticulum membrane	trans-2-enoyl-CoA reductase (NADPH) activity|very long-chain-acyl-CoA dehydrogenase activity			endometrium(1)|large_intestine(1)|ovary(1)	3						TTTCATCTACCTGCTCTTCTA	0.557000													25	193					0	0	1	0	0
SMARCB1	6598	broad.mit.edu	37	22	24167513	24167513	+	Silent	SNP	G	G	A	rs2229354	byFrequency	TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr22:24167513G>A	ENST00000344921.6	+	7	1131	c.924G>A	c.(922-924)tcG>tcA	p.S308S	SMARCB1_ENST00000407422.3_Silent_p.S290S|SMARCB1_ENST00000407082.3_Silent_p.S253S|SMARCB1_ENST00000263121.7_Silent_p.S299S			Q12824	SNF5_HUMAN	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	299	2 X approximate tandem repeats.|Interaction with PPP1R15A.				cell cycle|chromatin remodeling|DNA integration|interspecies interaction between organisms|nervous system development|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription from RNA polymerase II promoter|retroviral genome replication|transcription, DNA-dependent	nBAF complex|npBAF complex|nucleolus|nucleoplasm|SWI/SNF complex	p53 binding	p.?(6)|p.S299S(4)|p.L266_*386del(1)		bone(4)|central_nervous_system(198)|endometrium(4)|haematopoietic_and_lymphoid_tissue(25)|kidney(3)|large_intestine(5)|liver(2)|lung(5)|meninges(5)|ovary(4)|pancreas(1)|prostate(2)|skin(6)|soft_tissue(194)	458		Medulloblastoma(6;2.2e-09)|all_neural(6;2.73e-05)				AGCTGTGCTCGGAGCTGGGGT	0.547000			"""D, N, F, S"""		malignant rhabdoid	malignant rhabdoid							4	68					0	0	1	0	0
KCNA1	3736	broad.mit.edu	37	12	5021754	5021754	+	Missense_Mutation	SNP	G	G	A	rs104894355		TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr12:5021754G>A	ENST00000382545.3	+	2	2317	c.1210G>A	c.(1210-1212)Gta>Ata	p.V404I	KCNA1_ENST00000543874.2_Intron	NM_000217.2	NP_000208.2	Q09470	KCNA1_HUMAN	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	404			V -> I (in EA1; yields current amplitudes that were not different from wild-type; coexpression with wild-type partially corrected the alterations in activation parameters).		synaptic transmission	juxtaparanode region of axon|voltage-gated potassium channel complex	delayed rectifier potassium channel activity|potassium ion transmembrane transporter activity			NS(1)|breast(3)|cervix(2)|endometrium(5)|kidney(1)|large_intestine(14)|lung(23)|ovary(3)|pancreas(2)|prostate(3)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	63					Desflurane(DB01189)|Enflurane(DB00228)|Isoflurane(DB00753)|Methoxyflurane(DB01028)|Sevoflurane(DB01236)	TGCCCTGCCCGTACCTGTCAT	0.522000													144	246					0	0	1	0	0
GTF3C3	9330	broad.mit.edu	37	2	197657782	197657782	+	Silent	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr2:197657782C>T	ENST00000263956.3	-	3	398	c.309G>A	c.(307-309)gaG>gaA	p.E103E	GTF3C3_ENST00000409364.3_Silent_p.E103E	NM_012086.4	NP_036218.1	Q9Y5Q9	TF3C3_HUMAN	general transcription factor IIIC, polypeptide 3, 102kDa	103	Glu-rich.					transcription factor TFIIIC complex	DNA binding|protein binding	p.E103E(1)		breast(4)|endometrium(3)|kidney(1)|large_intestine(9)|lung(5)|ovary(3)|pancreas(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	33						cctcctcctcctcttcttcct	0.468000													4	46					0	0	1	0	0
OR51T1	401665	broad.mit.edu	37	11	4903279	4903279	+	Silent	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr11:4903279C>T	ENST00000380378.1	+	1	231	c.231C>T	c.(229-231)gtC>gtT	p.V77V	MMP26_ENST00000477339.1_Intron|OR51T1_ENST00000322049.1_Silent_p.V50V|MMP26_ENST00000380390.1_Intron	NM_001004759.1	NP_001004759.1	Q8NGJ9	O51T1_HUMAN	olfactory receptor, family 51, subfamily T, member 1	50					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(16)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)	34		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.086)		Epithelial(150;4.77e-12)|BRCA - Breast invasive adenocarcinoma(625;0.00435)|LUSC - Lung squamous cell carcinoma(625;0.19)		TCTTTCTTGTCATCATTACTA	0.483000													34	81					0	0	1	0	0
RP11-69H14.6	0	broad.mit.edu	37	15	22332432	22332432	+	RNA	SNP	C	C	T			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr15:22332432C>T	ENST00000558896.1	+	0	239																											AAGATTCTAACGTGACAGAAC	0.343000													5	110					0	0	1	0	0
RP11-114H24.7	0	broad.mit.edu	37	15	78212618	78212618	+	RNA	SNP	A	A	G			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr15:78212618A>G	ENST00000565869.1	+	0	111				RP11-114H24.2_ENST00000567226.1_RNA																							TGTAACCGCCACTGGAGGACC	0.562000													3	31					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				28	53					0	0	1	0	0
GGN	199720	broad.mit.edu	37	19	38877231	38877231	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr19:38877231G>A	ENST00000334928.6	-	3	803	c.671C>T	c.(670-672)gCg>gTg	p.A224V	GGN_ENST00000591809.1_Intron|AC005789.9_ENST00000585411.1_RNA	NM_152657.3	NP_689870.3	Q86UU5	GGN_HUMAN	gametogenetin	224	Interaction with GGNBP1 (By similarity).|Pro-rich.				cell differentiation|multicellular organismal development|spermatogenesis					breast(1)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(7)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	24	all_cancers(60;3.4e-06)		Lung(45;0.00172)|LUSC - Lung squamous cell carcinoma(53;0.00272)			GCCTTCGCCCGCATGGGGAGG	0.692000													3	32					0	0	1	0	0
COX10-AS1	0	broad.mit.edu	37	17	13927886	13927886	+	RNA	SNP	G	G	A	rs11649821	by1000genomes	TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr17:13927886G>A	ENST00000602743.1	-	0	224																											AACGGAGGGAGTGAGAGCCTT	0.562000													3	14					0	0	1	0	0
M1AP	130951	broad.mit.edu	37	2	74803681	74803681	+	Translation_Start_Site	SNP	G	G	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr2:74803681G>A	ENST00000358434.2	-	0	950				M1AP_ENST00000290536.5_Silent_p.D278D|M1AP_ENST00000409585.1_Silent_p.D278D|M1AP_ENST00000536235.1_Silent_p.D278D|M1AP_ENST00000464686.1_5'UTR					meiosis 1 associated protein																		TCAAGGAGCCGTCAGCTGTGC	0.483000													8	36					0	0	1	0	0
AC034193.5	0	broad.mit.edu	37	3	10035779	10035783	+	RNA	DEL	AGTCT	AGTCT	-	rs35714562		TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr3:10035779_10035783delAGTCT	ENST00000326237.3	+	0	354																											GGGGAAGAGAAGTCTGATCTGACAT	0.380													9	52	---	---	---	---					
GPRIN1	114787	broad.mit.edu	37	5	176026120	176026143	+	In_Frame_Del	DEL	CTCAAAGACCCAGGATCCTCCTTC	CTCAAAGACCCAGGATCCTCCTTC	-	rs146584332	byFrequency	TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr5:176026120_176026143delCTCAAAGACCCAGGATCCTCCTTC	ENST00000303991.4	-	2	870_893	c.693_716delGAAGGAGGATCCTGGGTCTTTGAG	c.(691-717)aga>ag	p.RKEDPGSLR231del		NM_052899.2	NP_443131.2	Q7Z2K8	GRIN1_HUMAN	G protein regulated inducer of neurite outgrowth 1	231				Missing (in Ref. 4; CAD38868).		growth cone|plasma membrane		p.L238L(1)		NS(1)|cervix(1)|endometrium(3)|kidney(1)|large_intestine(3)|liver(1)|lung(15)|ovary(2)|prostate(5)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	35	all_cancers(89;0.00263)|Renal(175;0.000269)|Lung NSC(126;0.00902)|all_lung(126;0.0142)	Medulloblastoma(196;0.0208)|all_neural(177;0.0416)	Kidney(164;3.85e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			ATCCACCTTTCTCAAAGACCCAGGATCCTCCTTCCTCGGTGACA	0.491													36	104	---	---	---	---					
STAG3L4	0	broad.mit.edu	37	7	66767611	66767612	+	RNA	DEL	TT	TT	-	rs12531701	by1000genomes	TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr7:66767611_66767612delTT	ENST00000416602.2	+	0	4_5					NR_040586.1		Q8TBR4	STG34_HUMAN												endometrium(2)|lung(5)	7		Lung NSC(55;0.0839)|all_lung(88;0.181)				ACCGGACTGCTTTTTTTTTTTT	0.545													4	6	---	---	---	---					
TMBIM4	51643	broad.mit.edu	37	12	66531936	66531937	+	Frame_Shift_Ins	INS	-	-	A			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr12:66531936_66531937insA	ENST00000358230.3	-	7	640_641	c.520_521insT	c.(520-522)tagfs	p.*174fs	TMBIM4_ENST00000539652.1_Intron|TMBIM4_ENST00000286424.7_Frame_Shift_Ins_p.*221fs|TMBIM4_ENST00000556010.1_Intron|TMBIM4_ENST00000542724.1_Frame_Shift_Ins_p.*143fs|TMBIM4_ENST00000398033.4_Frame_Shift_Ins_p.S159fs|TMBIM4_ENST00000544599.1_5'UTR	NM_016056.2	NP_057140.2	Q9HC24	TMBI4_HUMAN	transmembrane BAX inhibitor motif containing 4	174						integral to membrane	protein binding			central_nervous_system(1)|endometrium(1)|large_intestine(4)|ovary(1)|prostate(2)	9				GBM - Glioblastoma multiforme(28;0.0745)		TATCTCACTATAAAAAAAAAAC	0.351													7	42	---	---	---	---					
EP400	57634	broad.mit.edu	37	12	132547135	132547136	+	In_Frame_Ins	INS	-	-	CAG	rs144787206	byFrequency	TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr12:132547135_132547136insCAG	ENST00000333577.4	+	48	8440_8441	c.8331_8332insCAG	c.(8329-8334)caaaca>caCAGaaca	p.2777_2777Q>HR	EP400_ENST00000389562.2_In_Frame_Ins_p.2740_2740Q>HR|EP400_ENST00000330386.6_In_Frame_Ins_p.2660_2660Q>HR|EP400_ENST00000332482.4_In_Frame_Ins_p.2704_2704Q>HR|EP400_ENST00000389561.2_In_Frame_Ins_p.2741_2741Q>HR			Q96L91	EP400_HUMAN	E1A binding protein p400	2777	Interaction with ZNF42 (By similarity).|Poly-Gln.				histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent	NuA4 histone acetyltransferase complex|nuclear speck	ATP binding|DNA binding|helicase activity			NS(1)|breast(6)|central_nervous_system(10)|cervix(1)|endometrium(21)|kidney(13)|large_intestine(25)|lung(56)|ovary(5)|prostate(8)|skin(6)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	161	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.198)		OV - Ovarian serous cystadenocarcinoma(86;3.01e-08)|Epithelial(86;3.43e-07)|all cancers(50;2.01e-06)		agcagcagcagcaacagcagca	0.589													11	55	---	---	---	---					
FHOD1	29109	broad.mit.edu	37	16	67267852	67267852	+	Frame_Shift_Del	DEL	G	G	-			TCGA-DJ-A3V6-01A-11D-A22Z-08	TCGA-DJ-A3V6-10A-01D-A22Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	82fd9da2-097f-4cb1-8f68-56fa6b6d20ce	1d024108-51ca-4b2f-bd0e-aeb64ce669ba	g.chr16:67267852delG	ENST00000258201.4	-	13	2001	c.1754delC	c.(1753-1755)ctfs	p.P587fs	FHOD1_ENST00000567687.1_Frame_Shift_Del_p.P166fs	NM_013241.2	NP_037373.2	Q9Y613	FHOD1_HUMAN	formin homology 2 domain containing 1	587	FH1.|Poly-Pro.				actin cytoskeleton organization	cytoplasm|cytoskeleton|nucleus	actin binding	p.P585fs*43(1)		breast(4)|endometrium(3)|kidney(3)|large_intestine(5)|lung(7)|ovary(3)|prostate(1)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(2)	34		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.000691)|Epithelial(162;0.00462)|all cancers(182;0.0434)		AAGTGGGGGAGGGGGGGGTAC	0.622													10	15	---	---	---	---