Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ZNF92	168374	broad.mit.edu	37	7	64863822	64863822	+	Silent	SNP	T	T	C			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr7:64863822T>C	ENST00000328747.7	+	4	994	c.795T>C	c.(793-795)gcT>gcC	p.A265A	ZNF92_ENST00000431504.1_Silent_p.A189A|ZNF92_ENST00000357512.2_Silent_p.A233A|ZNF92_ENST00000450302.2_Silent_p.A196A	NM_152626.2	NP_689839.1	Q03936	ZNF92_HUMAN	zinc finger protein 92	265						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(2)|endometrium(1)|large_intestine(3)|lung(4)|pancreas(1)|skin(1)|stomach(1)	13		Lung NSC(55;0.159)				GTGGCAAAGCTTTTAACCGGT	0.373000													3	51					0	0	0.004672	0	0
RGS6	9628	broad.mit.edu	37	14	72961895	72961895	+	Missense_Mutation	SNP	A	A	G			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr14:72961895A>G	ENST00000553530.1	+	13	1097	c.890A>G	c.(889-891)gAc>gGc	p.D297G	RGS6_ENST00000556437.1_Missense_Mutation_p.D297G|RGS6_ENST00000434263.2_Missense_Mutation_p.D228G|RGS6_ENST00000406236.4_Missense_Mutation_p.D297G|RGS6_ENST00000555571.1_Missense_Mutation_p.D297G|RGS6_ENST00000553525.1_Missense_Mutation_p.D297G|RGS6_ENST00000343854.6_Intron|RGS6_ENST00000404301.2_Missense_Mutation_p.D297G|RGS6_ENST00000402788.2_Missense_Mutation_p.D297G|RGS6_ENST00000355512.6_Missense_Mutation_p.D297G|RGS6_ENST00000407322.4_Missense_Mutation_p.D297G|RGS6_ENST00000554782.1_Missense_Mutation_p.D158G	NM_001204417.1|NM_001204418.1|NM_001204420.1|NM_001204421.1|NM_001204422.1|NM_004296.5	NP_001191346.1|NP_001191347.1|NP_001191349.1|NP_001191350.1|NP_001191351.1|NP_004287.3	P49758	RGS6_HUMAN	regulator of G-protein signaling 6	297	G protein gamma.				G-protein coupled receptor protein signaling pathway|intracellular signal transduction|negative regulation of signal transduction|regulation of G-protein coupled receptor protein signaling pathway	cytoplasm|heterotrimeric G-protein complex	GTPase activator activity|signal transducer activity			endometrium(2)|kidney(3)|large_intestine(6)|lung(14)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	33				all cancers(60;0.00309)|BRCA - Breast invasive adenocarcinoma(234;0.0281)|STAD - Stomach adenocarcinoma(64;0.0302)|OV - Ovarian serous cystadenocarcinoma(108;0.0476)		GTGGAATATGACCCTTTGATA	0.428000													3	76					0	0	0.004672	0	0
FERMT1	55612	broad.mit.edu	37	20	6065760	6065760	+	Missense_Mutation	SNP	C	C	G			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr20:6065760C>G	ENST00000217289.4	-	12	2334	c.1546G>C	c.(1546-1548)Gaa>Caa	p.E516Q	FERMT1_ENST00000478194.1_5'UTR|FERMT1_ENST00000536936.1_Missense_Mutation_p.E259Q	NM_017671.4	NP_060141.3	Q9BQL6	FERM1_HUMAN	fermitin family member 1	516	FERM.				cell adhesion|establishment of epithelial cell polarity|keratinocyte migration|keratinocyte proliferation	cytosol|focal adhesion|ruffle membrane	binding			NS(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(3)|ovary(1)|pancreas(1)|prostate(2)|skin(2)	17						ACAAAACATTCTGGGTTCATA	0.418000													3	50					0	0	0.004672	0	0
CHTF18	63922	broad.mit.edu	37	16	845756	845756	+	Silent	SNP	C	C	T			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr16:845756C>T	ENST00000317063.6	+	19	2874	c.2874C>T	c.(2872-2874)cgC>cgT	p.R958R	CHTF18_ENST00000455171.2_Silent_p.R777R|CHTF18_ENST00000262315.9_Silent_p.R749R			Q8WVB6	CTF18_HUMAN	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	749					cell cycle|DNA replication	nucleus	ATP binding|DNA binding|nucleoside-triphosphatase activity			endometrium(1)|kidney(3)|liver(2)|lung(4)|prostate(1)	11		Hepatocellular(780;0.00335)				CAGCCACGCGCAGCCGGGCCA	0.701000													5	13					0	0	0.000602	0	0
HNRNPR	10236	broad.mit.edu	37	1	23645159	23645159	+	Silent	SNP	G	G	A			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr1:23645159G>A	ENST00000478691.1	-	7	811	c.540C>T	c.(538-540)ctC>ctT	p.L180L	HNRNPR_ENST00000374612.1_Silent_p.L278L|HNRNPR_ENST00000426846.2_Silent_p.L118L|HNRNPR_ENST00000606561.1_Silent_p.L139L|HNRNPR_ENST00000374616.3_Silent_p.L281L|HNRNPR_ENST00000302271.6_Silent_p.L278L|HNRNPR_ENST00000427764.2_Silent_p.L240L	NM_001102397.1|NM_001102399.1	NP_001095867.1|NP_001095869.1	O43390	HNRPR_HUMAN	heterogeneous nuclear ribonucleoprotein R	278	RRM 1.					catalytic step 2 spliceosome|cytoplasm|heterogeneous nuclear ribonucleoprotein complex|nucleoplasm	nucleotide binding|protein binding|RNA binding			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(1)|lung(8)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	19		Colorectal(325;3.46e-05)|Lung NSC(340;4.15e-05)|all_lung(284;6.64e-05)|Renal(390;0.000219)|Breast(348;0.00394)|Ovarian(437;0.00539)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|OV - Ovarian serous cystadenocarcinoma(117;6.83e-27)|Colorectal(126;6.01e-08)|COAD - Colon adenocarcinoma(152;3.32e-06)|GBM - Glioblastoma multiforme(114;6.69e-05)|BRCA - Breast invasive adenocarcinoma(304;0.00101)|KIRC - Kidney renal clear cell carcinoma(1967;0.00357)|STAD - Stomach adenocarcinoma(196;0.0131)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.0875)|LUSC - Lung squamous cell carcinoma(448;0.19)		GTTGATGATAGAGAATAACGT	0.463000													6	17					0	0	0.001168	0	0
OR5J2	282775	broad.mit.edu	37	11	55944860	55944860	+	Missense_Mutation	SNP	T	T	C	rs139886298		TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr11:55944860T>C	ENST00000312298.1	+	1	767	c.767T>C	c.(766-768)aTc>aCc	p.I256T		NM_001005492.1	NP_001005492.1	Q8NH18	OR5J2_HUMAN	olfactory receptor, family 5, subfamily J, member 2	256					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(30)|ovary(1)|pancreas(1)|prostate(1)|skin(1)|stomach(1)	44	Esophageal squamous(21;0.00693)					GGTACCTTAATCTTTAGCTAC	0.448000													4	63					0	0	0.000602	0	0
INADL	10207	broad.mit.edu	37	1	62550208	62550208	+	Nonsense_Mutation	SNP	C	C	G			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr1:62550208C>G	ENST00000371158.2	+	33	4379	c.4265C>G	c.(4264-4266)tCa>tGa	p.S1422*	INADL_ENST00000316485.6_Nonsense_Mutation_p.S1422*|INADL_ENST00000545929.1_Nonsense_Mutation_p.S95*|INADL_ENST00000543708.1_Nonsense_Mutation_p.S206*	NM_176877.2	NP_795352.2	Q8NI35	INADL_HUMAN	InaD-like (Drosophila)	1422					intracellular signal transduction|tight junction assembly	apical plasma membrane|perinuclear region of cytoplasm|tight junction	protein binding			breast(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(11)|large_intestine(8)|liver(1)|lung(51)|ovary(3)|pancreas(1)|prostate(7)|skin(5)|stomach(1)|upper_aerodigestive_tract(3)	103						GCTCCTCTGTCAGTGGACCCC	0.517000													4	44					0	0	0.000248	0	0
CHSY3	337876	broad.mit.edu	37	5	129520924	129520924	+	Nonsense_Mutation	SNP	A	A	T			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr5:129520924A>T	ENST00000305031.4	+	3	2447	c.2089A>T	c.(2089-2091)Aga>Tga	p.R697*		NM_175856.4	NP_787052.3	Q70JA7	CHSS3_HUMAN	chondroitin sulfate synthase 3	697						Golgi cisterna membrane|integral to membrane	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|metal ion binding|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity			central_nervous_system(1)|endometrium(1)|kidney(3)|large_intestine(7)|lung(9)|ovary(2)|pancreas(1)|prostate(2)|stomach(1)|urinary_tract(1)	28		all_cancers(142;0.0227)|Breast(839;0.198)|Prostate(80;0.215)|Lung NSC(810;0.239)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)	OV - Ovarian serous cystadenocarcinoma(64;0.136)		AGAGTTTTCCAGAGGTCTTGG	0.443000													8	30					0	0	0.003080	0	0
ARHGEF6	9459	broad.mit.edu	37	X	135827439	135827439	+	Silent	SNP	G	G	A			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chrX:135827439G>A	ENST00000250617.6	-	4	1607	c.402C>T	c.(400-402)aaC>aaT	p.N134N	ARHGEF6_ENST00000370620.1_5'UTR|ARHGEF6_ENST00000370622.1_5'UTR|ARHGEF6_ENST00000535227.1_5'UTR	NM_004840.2	NP_004831.1	Q15052	ARHG6_HUMAN	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	134					apoptosis|cell junction assembly|induction of apoptosis by extracellular signals|JNK cascade|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(12)|liver(1)|lung(14)|prostate(1)	38	Acute lymphoblastic leukemia(192;0.000127)					CTCCCTGTGGGTTTGTCTGAG	0.433000													53	92					0	0	0.003610	0	0
RP11-114H24.7	0	broad.mit.edu	37	15	78211648	78211648	+	RNA	SNP	A	A	G			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr15:78211648A>G	ENST00000565869.1	+	0	111				RP11-114H24.2_ENST00000567226.1_RNA																							CGCCAGGGATAGGGGCTCAGC	0.522000													3	53					0	0	0.004672	0	0
PBX2P1	0	broad.mit.edu	37	3	142895155	142895155	+	RNA	DEL	C	C	-			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr3:142895155delC	ENST00000560287.1	+	0	29																											GGCCTCAGGGCCCCCCCCCAG	0.746													3	3	---	---	---	---					
PDE2A	5138	broad.mit.edu	37	11	72353321	72353329	+	In_Frame_Del	DEL	GCGGCGGCG	GCGGCGGCG	-			TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr11:72353321_72353329delGCGGCGGCG	ENST00000334456.5	-	2	358_366	c.113_121delCGCCGCCGC	c.(112-123)cag>c	p.PPPQ38del	PDE2A_ENST00000544570.1_In_Frame_Del_p.PPPQ31del|PDE2A_ENST00000540345.1_In_Frame_Del_p.PPPQ29del|PDE2A_ENST00000418754.2_In_Frame_Del_p.PPPQ38del|PDE2A_ENST00000376450.3_In_Frame_Del_p.PPPQ31del|PDE2A_ENST00000444035.2_In_Frame_Del_p.PPPQ29del|PDE2A_ENST00000540380.1_Intron	NM_002599.4	NP_002590.1	O00408	PDE2A_HUMAN	phosphodiesterase 2A, cGMP-stimulated	38					platelet activation|signal transduction	cytosol	3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-GMP phosphodiesterase activity|cGMP binding|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|metal ion binding			breast(2)|endometrium(1)|kidney(3)|large_intestine(2)|lung(21)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	36			BRCA - Breast invasive adenocarcinoma(5;3.55e-05)		Sildenafil(DB00203)|Sulindac(DB00605)	GCGCATGGCTGCGGCGGCGGCGGCGGCTC	0.727													2	4	---	---	---	---					
TPTE2P6	0	broad.mit.edu	37	13	25157747	25157748	+	RNA	INS	-	-	T	rs144668552	by1000genomes	TCGA-EM-A2CU-01A-12D-A17V-08	TCGA-EM-A2CU-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	788fbfaa-51bf-42a4-afa6-5b87ed04c2d5	f0c68997-7104-43fb-b949-3ea4b958aab9	g.chr13:25157747_25157748insT	ENST00000453498.1	+	0	554																											AAAATGGGAGGTTTTTTTAGGG	0.411													2	4	---	---	---	---