Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
CXorf58	0	genome.wustl.edu	37	X	23957371	23957371	+	Missense_Mutation	SNP	C	C	T			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	X	23957371	23957371	C	T	SNP	CXorf58	ENST00000379211	human	ensembl	74_37	1	known	missense	c.950	p.T317M	0	NULL	NULL	0	no_errors	rs200387112	C->T	0	200	0	0	383	29	7.04	356	0	0.00	400	24	5.66
ZNF81	0	genome.wustl.edu	37	X	47774780	47774780	+	Silent	SNP	C	C	T			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	X	47774780	47774780	C	T	SNP	ZNF81	ENST00000338637	human	ensembl	74_37	1	known	silent	c.735	p.F245	0.752	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	0	no_errors	0	0	0	109	0	0	167	16	8.74	328	0	0.00	352	19	5.11
STAG2	0	genome.wustl.edu	37	X	123182926	123182926	+	Nonsense_Mutation	SNP	C	C	A			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	X	123182926	123182926	C	A	SNP	STAG2	ENST00000218089	human	ensembl	74_37	1	known	nonsense	c.891	p.Y297*	1	superfamily_ARM-type_fold	pfam_STAG,superfamily_ARM-type_fold	0	no_errors	0	0	0	57	0	0	94	15	13.76	335	0	0.00	325	40	10.93
DNAH6	0	genome.wustl.edu	37	2	84915588	84915588	+	Missense_Mutation	SNP	T	T	C			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	2	84915588	84915588	T	C	SNP	DNAH6	ENST00000237449	human	ensembl	74_37	1	known	missense	c.7163	p.I2388T	1	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	0	no_errors	0	0	0	47	0	0	66	6	8.33	220	0	0.00	231	13	5.33
MLH3	0	genome.wustl.edu	37	14	75513100	75513100	+	Missense_Mutation	SNP	C	C	T			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	14	75513100	75513100	C	T	SNP	MLH3	ENST00000355774	human	ensembl	74_37	-1	known	missense	c.3259	p.V1087M	1	NULL	pfam_MutL_C,pfam_DNA_mismatch_repair_C,pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_WW_dom,smart_MutL_C	0	no_errors	0	0	0	73	0	0	55	5	8.33	205	1	0.49	217	33	13.20
AKT1	0	genome.wustl.edu	37	14	105246482	105246482	+	Missense_Mutation	SNP	C	C	T			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	14	105246482	105246482	C	T	SNP	AKT1	ENST00000349310	human	ensembl	74_37	-1	known	missense	c.118	p.E40K	1	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Pleckstrin_homology,pfam_Pkinase_C,superfamily_Kinase-like_dom,smart_Pleckstrin_homology,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pfscan_Pleckstrin_homology,pfscan_Prot_kinase_dom	0	no_errors	0	0	0	50	0	0	44	6	12	168	0	0.00	160	30	15.79
DNAH3	0	genome.wustl.edu	37	16	21156603	21156603	+	Nonsense_Mutation	SNP	A	A	T			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	16	21156603	21156603	A	T	SNP	DNAH3	ENST00000261383	human	ensembl	74_37	-1	known	nonsense	c.347	p.L116*	0.98	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_AAA+_ATPase	0	no_errors	0	0	0	94	0	0	50	8	13.79	198	1	0.50	203	14	6.45
MT-RNR2	0	genome.wustl.edu	37	MT	2384	2384	+	RNA	SNP	A	A	G			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	MT	2384	2384	A	G	SNP	MT-RNR2	ENST00000387347	human	ensembl	74_37	1	known	rna	NULL	NULL	NULL	0	0	0	no_errors	0	0	0	149	0	0	205	24	10.48	1	0	0.00	0	0	0.00
ENSG00000203849	0	genome.wustl.edu	37	1	142713693	142713693	+	RNA	SNP	G	G	A			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	1	142713693	142713693	G	A	SNP	ENSG00000203849	ENST00000369381	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.539	0	0	0	no_errors	0	0	0	125	1	0.79	226	19	7.76	0	0	0.00	0	0	0.00
ENSG00000216154	0	genome.wustl.edu	37	4	123928724	123928749	+	RNA	DEL	TGTGTGTGTGTGTGTGTGTGTGTGTG	TGTGTGTGTGTGTGTGTGTGTGTGTG	-			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	TGTGTGTGTGTGTGTGTGTGTGTGTG	TGTGTGTGTGTGTGTGTGTGTGTGTG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	4	123928724	123928749	TGTGTGTGTGTGTGTGTGTGTGTGTG	0	DEL	ENSG00000216154	ENST00000401335	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.008:0.004:0.004:0.003:0.003:0.003:0.005:0.006:0.007:0.007:0.007:0.006:0.005:0.003:0.004:0.003:0.005:0.006:0.012:0.017:0.021:0.026:0.029:0.032:0.035:0.037	0	0	0	no_errors	rs148702654	ATGTGTGTGTGTGTGTGTGTGTGTGTG->A	0	27	0	0	22	4	15.38	0	0	0.00	0	0	0.00
MAML2	0	genome.wustl.edu	37	11	95825372	95825374	+	In_Frame_Del	DEL	TGT	TGT	-			TCGA-4V-A9QQ-01A-11D-A423-09	TCGA-4V-A9QQ-10B-01D-A426-09	TGT	TGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f2a14e3b-0b71-4e83-80dc-12ecb6f23e6a	5fbd240c-3130-4de3-a25a-ab3939ce41bb	11	95825372	95825374	TGT	0	DEL	MAML2	ENST00000524717	human	ensembl	74_37	-1	known	in_frame_del	c.1823_1821	p.Q611in_frame_del	0.003:0.003:0.003	NULL	pfam_Neuroggenic_mastermind-like_N	0	no_errors	0	0	0	43	1	2.27	20	6	23.08	3	0	0.00	5	0	0.00