Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
ATP11C	0	genome.wustl.edu	37	X	138886758	138886758	+	Missense_Mutation	SNP	C	C	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	X	138886758	138886758	C	A	SNP	ATP11C	ENST00000327569	human	ensembl	74_37	-1	known	missense	c.436	p.V146F	1	pfam_ATPase_P-typ_transduc_dom_A,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	0	no_errors	0	0	0	95	0	0	169	18	9.63	92	0	0.00	106	9	7.83
MSH4	0	genome.wustl.edu	37	1	76342640	76342640	+	Missense_Mutation	SNP	A	A	G			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	1	76342640	76342640	A	G	SNP	MSH4	ENST00000263187	human	ensembl	74_37	1	known	missense	c.1325	p.N442S	0.627	pfam_DNA_mismatch_repair_MutS_core,superfamily_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_core	pfam_DNA_mismatch_repair_MutS_C,pfam_DNA_mismatch_repair_MutS_core,pfam_DNA_mmatch_repair_MutS_con_dom,pfam_DNA_mismatch_repair_MutS_clamp,superfamily_DNA_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_DNA_mmatch_repair_MutS_con_dom,smart_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_C	0	no_errors	0	0	0	66	0	0	75	25	25	171	0	0.00	154	46	23.00
PRG4	0	genome.wustl.edu	37	1	186275527	186275527	+	Silent	SNP	T	T	C			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	1	186275527	186275527	T	C	SNP	PRG4	ENST00000445192	human	ensembl	74_37	1	known	silent	c.676	p.L226	0.712	NULL	pfam_Somatomedin_B_dom,pfam_Hemopexin-like_repeat,superfamily_Hemopexin-like_dom,smart_Somatomedin_B_dom,smart_Hemopexin-like_repeat,prints_Somatomedin_B_chordata,pfscan_Somatomedin_B_dom	0	no_errors	0	0	0	59	0	0	67	18	21.18	226	0	0.00	209	81	27.65
SEL1L3	0	genome.wustl.edu	37	4	25780763	25780763	+	Nonsense_Mutation	SNP	C	C	T			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	4	25780763	25780763	C	T	SNP	SEL1L3	ENST00000399878	human	ensembl	74_37	-1	known	nonsense	c.2520	p.W840*	1	smart_Sel1-like	pfam_Sel1-like,superfamily_ConA-like_lec_gl_sf,smart_Sel1-like	0	no_errors	0	0	0	52	0	0	28	17	37.78	209	0	0.00	155	56	26.54
ADAMTS3	0	genome.wustl.edu	37	4	73177944	73177944	+	RNA	SNP	C	C	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	4	73177944	73177944	C	A	SNP	ADAMTS3	ENST00000511274	human	ensembl	74_37	-1	known	rna	NULL	NULL	0	0	0	0	no_errors	0	0	0	49	0	0	37	24	39.34	186	0	0.00	162	72	30.77
UBLCP1	0	genome.wustl.edu	37	5	158697618	158697618	+	Missense_Mutation	SNP	C	C	G			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	5	158697618	158697618	C	G	SNP	UBLCP1	ENST00000296786	human	ensembl	74_37	1	known	missense	c.415	p.L139V	1	pfam_NIF,superfamily_HAD-like_dom,smart_NIF,pfscan_NIF,tigrfam_HAD-SF_hydro_IIID	pfam_NIF,pfam_Ubiquitin_dom,superfamily_HAD-like_dom,smart_Ubiquitin_dom,smart_NIF,pfscan_NIF,pfscan_Ubiquitin_supergroup,tigrfam_HAD-SF_hydro_IIID	0	no_errors	0	0	0	32	0	0	64	12	15.79	236	0	0.00	190	93	32.86
ZSCAN12	0	genome.wustl.edu	37	6	28358990	28358990	+	Silent	SNP	G	G	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	6	28358990	28358990	G	A	SNP	ZSCAN12	ENST00000361028	human	ensembl	74_37	-1	known	silent	c.1077	p.H359	0.895	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	0	no_errors	0	0	0	133	0	0	165	26	13.61	150	0	0.00	155	12	7.19
FIG4	0	genome.wustl.edu	37	6	110062669	110062669	+	Silent	SNP	A	A	G			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	6	110062669	110062669	A	G	SNP	FIG4	ENST00000230124	human	ensembl	74_37	1	known	silent	c.798	p.P266	0.869	pfam_Syja_N,pfscan_Syja_N	pfam_Syja_N,pfscan_Syja_N	0	no_errors	0	0	0	48	0	0	62	5	7.46	223	0	0.00	209	24	10.30
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	225	0	0	292	101	25.7	130	0	0.00	84	46	35.38
FSCN3	0	genome.wustl.edu	37	7	127240363	127240363	+	Missense_Mutation	SNP	C	C	G			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	7	127240363	127240363	C	G	SNP	FSCN3	ENST00000420086	human	ensembl	74_37	1	known	missense	c.1000	p.P334A	0.96	NULL	pfam_Fascin-domain,superfamily_Actin_cross-linking	0	no_errors	0	0	0	63	0	0	55	13	19.12	145	1	0.68	122	48	28.24
CSMD1	0	genome.wustl.edu	37	8	3855580	3855580	+	Silent	SNP	G	G	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	8	3855580	3855580	G	A	SNP	CSMD1	ENST00000520002	human	ensembl	74_37	-1	known	silent	c.663	p.S221	1	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	0	no_errors	0	0	0	60	0	0	47	15	24.19	153	0	0.00	96	44	31.43
NTRK2	0	genome.wustl.edu	37	9	87285831	87285831	+	Silent	SNP	G	G	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	9	87285831	87285831	G	A	SNP	NTRK2	ENST00000277120	human	ensembl	74_37	1	known	silent	c.168	p.P56	0.613	pfam_LRR-contain_N,smart_LRR-contain_N	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,pfam_LRR-contain_N,superfamily_Kinase-like_dom,smart_LRR-contain_N,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_Tyr_kinase_NGF_rcpt,prints_Tyr_kin_neurotrophic_rcpt_2	0	no_errors	0	0	0	69	0	0	57	24	29.63	129	0	0.00	79	35	30.70
COL17A1	0	genome.wustl.edu	37	10	105796368	105796368	+	Silent	SNP	T	T	C			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	10	105796368	105796368	T	C	SNP	COL17A1	ENST00000353479	human	ensembl	74_37	-1	known	silent	c.3300	p.L1100	0.061	NULL	pfam_Collagen	0	no_errors	0	0	0	27	0	0	19	7	26.92	87	0	0.00	61	22	26.51
OTOGL	0	genome.wustl.edu	37	12	80752501	80752501	+	Missense_Mutation	SNP	A	A	G			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	12	80752501	80752501	A	G	SNP	OTOGL	ENST00000458043	human	ensembl	74_37	1	known	missense	c.6145	p.M2049V	1	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_AbfB,superfamily_AbfB,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_Cys_knot_C,pfscan_Cys_knot_C	0	no_errors	0	0	0	45	0	0	48	27	36	224	0	0.00	203	71	25.91
LTBP2	0	genome.wustl.edu	37	14	75052588	75052588	+	Missense_Mutation	SNP	A	A	C			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	14	75052588	75052588	A	C	SNP	LTBP2	ENST00000261978	human	ensembl	74_37	-1	known	missense	c.799	p.S267A	0.592	NULL	pfam_EGF-like_Ca-bd_dom,pfam_TB_dom,pfam_EG-like_dom,superfamily_TB_dom,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	0	no_errors	0	0	0	72	0	0	46	15	24.59	155	1	0.64	85	18	17.31
TSHZ1	0	genome.wustl.edu	37	18	72999958	72999958	+	Missense_Mutation	SNP	G	G	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	18	72999958	72999958	G	A	SNP	TSHZ1	ENST00000580243	human	ensembl	74_37	1	known	missense	c.2596	p.D866N	1	NULL	superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Znf_C2H2	0	no_errors	0	0	0	32	0	0	20	7	25.93	129	0	0.00	95	26	21.49
CACNA1A	0	genome.wustl.edu	37	19	13340904	13340904	+	Silent	SNP	G	G	A			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	19	13340904	13340904	G	A	SNP	CACNA1A	ENST00000360228	human	ensembl	74_37	-1	known	silent	c.5520	p.P1840	0.997	NULL	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,prints_VDCCAlpha1,prints_VDCC_P/Q_a1su	0	no_errors	0	0	0	32	1	3.03	32	14	30.43	159	1	0.62	136	49	26.34
ENSG00000230615	0	genome.wustl.edu	37	1	44569967	44569968	+	RNA	INS	-	-	GCC			TCGA-5V-A9RR-01A-11D-A423-09	TCGA-5V-A9RR-10A-01D-A426-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a3666d9a-a700-4585-b624-fd77c56d8eed	3fcb2ae1-134f-4863-b07a-9589142ada4b	1	44569967	44569968	0	GCC	INS	ENSG00000230615	ENST00000434244	human	ensembl	74_37	1	known	rna	NULL	NULL	1.000:0.999	0	0	0	no_errors	rs369247676	T->TGCC	0	16	0	0	21	6	22.22	0	0	0.00	0	0	0.00