Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
IQSEC2	0	genome.wustl.edu	37	X	53272536	53272536	+	Missense_Mutation	SNP	C	C	T			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	X	53272536	53272536	C	T	SNP	IQSEC2	ENST00000396435	human	ensembl	74_37	-1	known	missense	c.2867	p.R956H	1	NULL	pfam_Sec7_dom,superfamily_Sec7_dom,superfamily_P-loop_NTPase,smart_Sec7_dom,smart_Pleckstrin_homology,pfscan_IQ_motif_EF-hand-BS,pfscan_Sec7_dom	0	no_errors	0	0	0	25	0	0	13	3	18.75	100	0	0.00	91	31	25.41
TBC1D8B	0	genome.wustl.edu	37	X	106064109	106064109	+	Missense_Mutation	SNP	G	G	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	X	106064109	106064109	G	A	SNP	TBC1D8B	ENST00000357242	human	ensembl	74_37	1	known	missense	c.244	p.A82T	1	NULL	pfam_Rab-GTPase-TBC_dom,pfam_GRAM,superfamily_Rab-GTPase-TBC_dom,smart_GRAM,smart_Rab-GTPase-TBC_dom,pfscan_EF_hand_dom,pfscan_Rab-GTPase-TBC_dom	0	no_errors	0	0	0	306	0	0	160	41	20.4	207	0	0.00	188	52	21.67
ATXN7L2	0	genome.wustl.edu	37	1	110031490	110031490	+	Missense_Mutation	SNP	C	C	T			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	1	110031490	110031490	C	T	SNP	ATXN7L2	ENST00000369870	human	ensembl	74_37	1	known	missense	c.805	p.R269W	1	pfam_SCA7_dom	pfam_SCA7_dom	0	no_errors	0	0	0	31	0	0	20	3	13.04	77	0	0.00	121	11	8.33
NES	0	genome.wustl.edu	37	1	156640813	156640813	+	Missense_Mutation	SNP	G	G	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	1	156640813	156640813	G	A	SNP	NES	ENST00000368223	human	ensembl	74_37	-1	known	missense	c.3167	p.P1056L	0.001	NULL	pfam_IF	0	no_errors	0	0	0	42	0	0	21	5	19.23	57	0	0.00	46	17	26.98
FNIP1	0	genome.wustl.edu	37	5	131006239	131006239	+	Missense_Mutation	SNP	C	C	T			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	5	131006239	131006239	C	T	SNP	FNIP1	ENST00000510461	human	ensembl	74_37	-1	known	missense	c.3025	p.V1009M	1	NULL	NULL	0	no_errors	0	0	0	123	1	0.81	58	18	23.08	167	0	0.00	154	37	19.37
HEBP2	0	genome.wustl.edu	37	6	138726307	138726307	+	Missense_Mutation	SNP	A	A	G			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	6	138726307	138726307	A	G	SNP	HEBP2	ENST00000607197	human	ensembl	74_37	1	known	missense	c.128	p.Y43C	1	pfam_SOUL_haem-bd,superfamily_Reg_factor_effector_dom	pfam_SOUL_haem-bd,superfamily_Reg_factor_effector_dom	0	no_errors	0	0	0	78	1	1.27	53	12	18.46	164	0	0.00	192	35	15.35
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	438	0	0	287	62	17.77	79	0	0.00	102	31	23.31
SVEP1	0	genome.wustl.edu	37	9	113259212	113259212	+	Silent	SNP	G	G	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	9	113259212	113259212	G	A	SNP	SVEP1	ENST00000401783	human	ensembl	74_37	-1	known	silent	c.1683	p.D561	0.99	pfam_Hyalin,pfscan_Hyalin,pfscan_Sushi_SCR_CCP	pfam_Sushi_SCR_CCP,pfam_EG-like_dom,pfam_Tyr-kin_ephrin_A/B_rcpt-like,pfam_Hyalin,pfam_VWF_A,pfam_Pentaxin,pfam_EGF_extracell,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Sushi_SCR_CCP,superfamily_Growth_fac_rcpt_N_dom,smart_VWF_A,smart_Sushi_SCR_CCP,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_Pentaxin,pfscan_EG-like_dom,pfscan_Hyalin,pfscan_Sushi_SCR_CCP,pfscan_VWF_A,prints_Pentaxin	0	no_errors	rs75422692	G->A	0.9996,0.0003994	71	0	0	37	13	26	130	0	0.00	161	33	17.01
ENKUR	0	genome.wustl.edu	37	10	25304802	25304802	+	Missense_Mutation	SNP	G	G	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	10	25304802	25304802	G	A	SNP	ENKUR	ENST00000331161	human	ensembl	74_37	-1	known	missense	c.64	p.P22S	0.95	NULL	NULL	0	no_errors	0	0	0	63	0	0	23	9	28.12	143	0	0.00	158	21	11.60
EPC1	0	genome.wustl.edu	37	10	32582521	32582521	+	Missense_Mutation	SNP	T	T	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	10	32582521	32582521	T	A	SNP	EPC1	ENST00000263062	human	ensembl	74_37	-1	known	missense	c.458	p.Q153L	1	NULL	pfam_Enhancer_polycomb_C,pfam_Enhancer_polycomb-like_N	0	no_errors	0	0	0	26	0	0	22	3	12	174	1	0.57	194	60	23.62
RGR	0	genome.wustl.edu	37	10	86007481	86007481	+	Missense_Mutation	SNP	G	G	C			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	10	86007481	86007481	G	C	SNP	RGR	ENST00000359452	human	ensembl	74_37	1	known	missense	c.214	p.A72P	0.972	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_RPE_GPCR,prints_GPCR_Rhodpsn	0	no_errors	0	0	0	39	0	0	36	7	16.28	70	0	0.00	72	20	21.74
TMEM223	0	genome.wustl.edu	37	11	62559355	62559355	+	Missense_Mutation	SNP	C	C	G			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	11	62559355	62559355	C	G	SNP	TMEM223	ENST00000307366	human	ensembl	74_37	-1	known	missense	c.112	p.E38Q	0.999	NULL	NULL	0	no_errors	0	0	0	26	0	0	16	4	20	36	0	0.00	35	6	14.63
SCYL2	0	genome.wustl.edu	37	12	100691878	100691878	+	Silent	SNP	T	T	C			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	12	100691878	100691878	T	C	SNP	SCYL2	ENST00000360820	human	ensembl	74_37	1	known	silent	c.405	p.N135	0.995	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	0	no_errors	0	0	0	135	0	0	93	12	11.43	118	0	0.00	112	25	18.25
MIR484	0	genome.wustl.edu	37	16	15737165	15737165	+	RNA	SNP	C	C	T			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	16	15737165	15737165	C	T	SNP	MIR484	ENST00000606601	human	ensembl	74_37	1	known	rna	NULL	NULL	1	0	0	0	no_errors	0	0	0	218	0	0	133	21	13.64	84	0	0.00	105	8	7.08
SPATA31A7	0	genome.wustl.edu	37	9	65505560	65505560	+	Missense_Mutation	SNP	G	G	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	9	65505560	65505560	G	A	SNP	SPATA31A7	ENST00000355045	human	ensembl	74_37	-1	known	missense	c.2000	p.P667L	0	NULL	NULL	0	no_errors	rs200832265	G->A	0	55	1	1.79	42	11	20.75	0	0	0.00	0	0	0.00
LOC101927601	0	genome.wustl.edu	37	15	82635183	82635183	+	Missense_Mutation	SNP	A	A	C			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	15	82635183	82635183	A	C	SNP	LOC101927601	ENST00000439287	human	ensembl	74_37	-1	known	missense	c.1387	p.C463G	0.264	NULL	NULL	0	no_errors	rs62010119	A->C	0	42	0	0	31	4	11.43	0	0	0.00	0	0	0.00
ZNF208	0	genome.wustl.edu	37	19	22154191	22154191	+	Silent	SNP	G	G	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	19	22154191	22154191	G	A	SNP	ZNF208	ENST00000397126	human	ensembl	74_37	-1	novel	silent	c.3645	p.H1215	0.339	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	0	no_errors	rs542502577	G->A	0.9996,0.0003994	67	0	0	32	4	10.81	1	0	0.00	1	0	0.00
ZNF208	0	genome.wustl.edu	37	19	22154197	22154197	+	Missense_Mutation	SNP	T	T	A			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	19	22154197	22154197	T	A	SNP	ZNF208	ENST00000397126	human	ensembl	74_37	-1	novel	missense	c.3639	p.R1213S	0	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	0	no_errors	rs560585093	T->A	0.9998,0.0001997	69	0	0	42	4	8.7	1	0	0.00	1	0	0.00
ZDHHC8P1	0	genome.wustl.edu	37	22	23734810	23734810	+	RNA	SNP	G	G	T			TCGA-YT-A95F-01A-11D-A428-09	TCGA-YT-A95F-10A-01D-A42B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	0c7c91b7-5b7f-4531-849d-2b85635b3e6e	9b6e27a6-3a33-4a1e-b627-efa66d59382e	22	23734810	23734810	G	T	SNP	ZDHHC8P1	ENST00000456279	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.787	0	0	0	no_errors	0	0	0	31	0	0	32	4	11.11	13	0	0.00	10	0	0.00