Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error rsID rsID_ref_var_alleles CAF normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumor_var_reads tumor_vaf normal_ref_reads_val normal_var_reads_val normal_vaf_val tumor_ref_reads_val tumor_var_reads_val tumor_vaf_val HLA-DQB2 0 genome.wustl.edu 37 6 32726788 32726788 + Missense_Mutation SNP T T C TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 6 32726788 32726788 T C SNP HLA-DQB2 ENST00000435145 human ensembl 74_37 -1 known missense c.485 p.D162G 0.997 pfam_Ig_C1-set,pfam_CD80_C2-set,smart_Ig_C1-set,pfscan_Ig-like_dom pfam_MHC_II_b_N,pfam_Ig_C1-set,pfam_CD80_C2-set,superfamily_MHC_I/II-like_Ag-recog,smart_MHC_II_b_N,smart_Ig_C1-set,pfscan_Ig-like_dom 0 no_errors rs56536369 T->C 0 51 1 1.92 31 5 13.89 66 0 0.00 41 2 4.65 RBAK 0 genome.wustl.edu 37 7 5104287 5104287 + Silent SNP T T G TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 7 5104287 5104287 T G SNP RBAK ENST00000353796 human ensembl 74_37 1 known silent c.1200 p.L400 0.552 pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 40 0 0 50 9 15.25 169 0 0.00 125 13 9.42 DNAH11 0 genome.wustl.edu 37 7 21723504 21723504 + Missense_Mutation SNP T T C TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 7 21723504 21723504 T C SNP DNAH11 ENST00000328843 human ensembl 74_37 1 known missense c.5584 p.Y1862H 1 NULL pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase 0 no_errors 0 0 0 84 0 0 87 9 9.38 230 0 0.00 168 21 11.11 TH 0 genome.wustl.edu 37 11 2185541 2185541 + Silent SNP G G A TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 11 2185541 2185541 G A SNP TH ENST00000381178 human ensembl 74_37 -1 known silent c.1509 p.P503 0.978 pfam_Aromatic-AA_hydroxylase_C,superfamily_Aromatic-AA_hydroxylase_C,pirsf_Tyrosine_3-monooxygenase-like,tigrfam_Tyr_3_mOase pfam_Aromatic-AA_hydroxylase_C,pfam_Tyrosine_hydroxylase_CS,superfamily_Aromatic-AA_hydroxylase_C,pirsf_Tyrosine_3-monooxygenase-like,prints_Aromatic-AA_hydroxylase_C,tigrfam_Tyr_3_mOase 0 no_errors 0 0 0 31 0 0 66 15 18.52 33 0 0.00 44 4 8.33 SOX5 0 genome.wustl.edu 37 12 23818447 23818447 + Missense_Mutation SNP G G A TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 12 23818447 23818447 G A SNP SOX5 ENST00000451604 human ensembl 74_37 -1 known missense c.862 p.R288W 1 NULL pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom 0 no_errors rs557463084 G->A 0.9998,0.0001997 103 0 0 78 14 15.22 78 0 0.00 63 3 4.55 KRT3 0 genome.wustl.edu 37 12 53183951 53183951 + Missense_Mutation SNP C C T TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 12 53183951 53183951 C T SNP KRT3 ENST00000309505 human ensembl 74_37 -1 known missense c.1765 p.G589S 0.004 NULL pfam_IF,superfamily_Prefoldin,prints_Keratin_II,prints_Keratin_I 0 no_errors 0 0 0 20 0 0 24 5 17.24 27 0 0.00 25 5 16.67 MED13L 0 genome.wustl.edu 37 12 116445404 116445404 + Nonsense_Mutation SNP G G A TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 12 116445404 116445404 G A SNP MED13L ENST00000281928 human ensembl 74_37 -1 known nonsense c.2050 p.Q684* 1 NULL pfam_Mediator_Med13,pfam_Mediator_Med13_N_met/fun 0 no_errors 0 0 0 37 0 0 38 4 9.52 133 2 1.45 83 12 12.50 CYP1A2 0 genome.wustl.edu 37 15 75047181 75047181 + Missense_Mutation SNP G G T TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 15 75047181 75047181 G T SNP CYP1A2 ENST00000343932 human ensembl 74_37 1 known missense c.1303 p.A435S 0.001 pfam_Cyt_P450,superfamily_Cyt_P450 pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-I_CYP1,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450 0 no_errors 0 0 0 52 0 0 42 10 19.23 102 0 0.00 62 12 16.22 EPG5 0 genome.wustl.edu 37 18 43497645 43497645 + Nonsense_Mutation SNP G G A TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 18 43497645 43497645 G A SNP EPG5 ENST00000282041 human ensembl 74_37 -1 known nonsense c.3238 p.Q1080* 1 NULL NULL 0 no_errors 0 0 0 78 0 0 64 5 7.25 234 0 0.00 122 7 5.43 SETD1A 0 genome.wustl.edu 37 16 30982809 30982811 + In_Frame_Del DEL TCC TCC - TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 TCC TCC TCC - TCC TCC Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 16 30982809 30982811 TCC 0 DEL SETD1A ENST00000262519 human ensembl 74_37 1 known in_frame_del c.3127_3129 p.S1046in_frame_del 0.734:0.781:0.676 NULL pfam_COMPASS_Set1_N-SET,pfam_SET_dom,pfam_RRM_dom,smart_RRM_dom,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_RRM_dom 0 no_errors 0 0 0 30 0 0 28 4 12.5 44 0 0.00 18 3 14.29 KRTAP4-8 0 genome.wustl.edu 37 17 39254149 39254149 + Missense_Mutation SNP G G C TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 17 39254149 39254149 G C SNP KRTAP4-8 ENST00000333822 human ensembl 74_37 -1 known missense c.188 p.T63S 0.004 pfam_Keratin-assoc pfam_Keratin-assoc 0 no_errors rs201246375 G->C 0 38 0 0 46 6 11.54 1 0 0.00 1 0 0.00 EIF3L 0 genome.wustl.edu 37 22 38273724 38273724 + Missense_Mutation SNP C C T TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 22 38273724 38273724 C T SNP EIF3L ENST00000412331 human ensembl 74_37 1 known missense c.1121 p.A374V 1 pfam_eIF3l pfam_eIF3l 0 no_errors 0 0 0 54 0 0 53 4 7.02 32 0 0.00 10 0 0.00 KIF13A 0 genome.wustl.edu 37 6 17987760 17987795 + RNA DEL GCCGCCGCCGCTGCAGCCGCGCGCCCCTCGAGCGCG GCCGCCGCCGCTGCAGCCGCGCGCCCCTCGAGCGCG - TCGA-YT-A95G-01A-11D-A428-09 TCGA-YT-A95G-10A-01D-A42B-09 GCCGCCGCCGCTGCAGCCGCGCGCCCCTCGAGCGCG GCCGCCGCCGCTGCAGCCGCGCGCCCCTCGAGCGCG Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 0a9bee25-52ee-4f84-a427-fde2e33be3af 3a465c7f-e359-471f-824c-ee4801836e8c 6 17987760 17987795 GCCGCCGCCGCTGCAGCCGCGCGCCCCTCGAGCGCG 0 DEL KIF13A ENST00000507576 human ensembl 74_37 -1 known rna NULL NULL 0.001:0.001:0.002:0.000:0.000:0.003:0.006:0.003:0.455:0.402:0.335:0.038:0.016:0.010:0.001:0.001:0.005:0.005:0.001:0.002:0.024:0.001:0.001:0.002:0.001:0.003:0.006:0.007:0.016:0.080:0.100:0.188:0.265:0.293:0.305:0.304 0 0 0 no_errors 0 0 0 16 0 0 10 4 28.57 0 0 0.00 0 0 0.00