Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
MT-RNR2	0	genome.wustl.edu	37	MT	2589	2589	+	RNA	SNP	A	A	G			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	MT	2589	2589	A	G	SNP	MT-RNR2	ENST00000387347	human	ensembl	74_37	1	known	rna	NULL	NULL	NULL	0	0	0	no_errors	0	0	0	1392	1	0.07	70	2353	96.71	2	0	0.00	0	2	100.00
SPEN	0	genome.wustl.edu	37	1	16257221	16257221	+	Missense_Mutation	SNP	A	A	C			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	1	16257221	16257221	A	C	SNP	SPEN	ENST00000375759	human	ensembl	74_37	1	known	missense	c.4486	p.K1496Q	1	NULL	pfam_RRM_dom,pfam_SPOC_C,superfamily_SPOC_like_C_dom,smart_RRM_dom,pfscan_SPOC_met,pfscan_RRM_dom	0	no_errors	0	0	0	49	0	0	43	6	12.24	328	1	0.30	238	13	5.18
BLZF1	0	genome.wustl.edu	37	1	169349772	169349772	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	1	169349772	169349772	G	A	SNP	BLZF1	ENST00000329281	human	ensembl	74_37	1	known	missense	c.722	p.R241H	1	NULL	pfam_Hsk3_like	0	no_errors	0	0	0	48	0	0	30	38	55.88	229	0	0.00	104	75	41.90
DNAJC27	0	genome.wustl.edu	37	2	25194751	25194751	+	Missense_Mutation	SNP	C	C	A			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	2	25194751	25194751	C	A	SNP	DNAJC27	ENST00000264711	human	ensembl	74_37	-1	known	missense	c.23	p.R8L	1	NULL	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_DnaJ_domain,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,superfamily_DnaJ_domain,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,smart_DnaJ_domain,pfscan_DnaJ_domain,prints_Small_GTPase,prints_DnaJ_domain,tigrfam_Small_GTP-bd_dom	0	no_errors	0	0	0	74	0	0	43	44	50.57	88	0	0.00	44	30	40.54
GPD2	0	genome.wustl.edu	37	2	157436212	157436212	+	Missense_Mutation	SNP	T	T	G			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	2	157436212	157436212	T	G	SNP	GPD2	ENST00000310454	human	ensembl	74_37	1	known	missense	c.1970	p.V657G	0.835	pfscan_EF_hand_dom	pfam_FAD-dep_OxRdtase,pfam_FAD_bind_dom,smart_EF_hand_dom,pfscan_EF_hand_dom,prints_G3P_DH_FAD-dep	0	no_errors	0	0	0	70	0	0	59	6	9.23	122	0	0.00	93	7	7.00
VARS	0	genome.wustl.edu	37	6	31760543	31760543	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	6	31760543	31760543	G	A	SNP	VARS	ENST00000375663	human	ensembl	74_37	-1	known	missense	c.652	p.H218Y	0.951	superfamily_Glutathione-S-Trfase_C-like	pfam_aa-tRNA-synth_Ia,pfam_V/L/I-tRNA-synth_anticodon-bd,pfam_Glutathione_S-Trfase_N,pfam_Methionyl/Leucyl_tRNA_Synth,pfam_GST_C,superfamily_Val/Leu/Ile-tRNA-synth_edit,superfamily_tRNAsynth_1a_anticodon-bd,superfamily_Glutathione-S-Trfase_C-like,superfamily_tRNA-bd_arm,prints_Valyl-tRNA_ligase,tigrfam_Valyl-tRNA_ligase	0	no_errors	0	0	0	56	0	0	54	37	40.66	256	0	0.00	141	82	36.61
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	351	0	0	195	183	48.16	148	1	0.67	64	74	53.62
HRAS	0	genome.wustl.edu	37	11	533552	533552	+	Missense_Mutation	SNP	C	C	G			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	11	533552	533552	C	G	SNP	HRAS	ENST00000311189	human	ensembl	74_37	-1	known	missense	c.351	p.K117N	0.999	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,pfam_Fe2_transport_prot_B_N,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,pfam_Fe2_transport_prot_B_N,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	0	no_errors	0	0	0	44	0	0	15	19	55.88	205	0	0.00	67	47	40.87
NPAT	0	genome.wustl.edu	37	11	108043017	108043017	+	Silent	SNP	A	A	T			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	11	108043017	108043017	A	T	SNP	NPAT	ENST00000278612	human	ensembl	74_37	-1	known	silent	c.2694	p.T898	0.007	NULL	smart_LisH_dimerisation,pfscan_LisH_dimerisation	0	no_errors	0	0	0	51	0	0	38	26	40.62	244	1	0.41	111	92	45.10
PCSK7	0	genome.wustl.edu	37	11	117089217	117089217	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	11	117089217	117089217	G	A	SNP	PCSK7	ENST00000320934	human	ensembl	74_37	-1	known	missense	c.1499	p.P500L	0.99	superfamily_Galactose-bd-like	pfam_Peptidase_S8/S53_dom,pfam_PrprotnconvertsP,superfamily_Peptidase_S8/S53_dom,superfamily_Galactose-bd-like,superfamily_Prot_inh_propept,prints_Peptidase_S8_subtilisin-rel	0	no_errors	0	0	0	53	0	0	14	38	73.08	321	0	0.00	96	92	48.94
PUS1	0	genome.wustl.edu	37	12	132426425	132426425	+	Missense_Mutation	SNP	T	T	C			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	12	132426425	132426425	T	C	SNP	PUS1	ENST00000376649	human	ensembl	74_37	1	known	missense	c.1133	p.I378T	0.093	NULL	pfam_PsdUridine_synth_TruA_a/b_dom,superfamily_PsdUridine_synth_cat_dom,tigrfam_PsdUridine_synth_TruA	0	no_errors	0	0	0	28	0	0	16	7	30.43	130	0	0.00	58	33	36.26
MIR3188	0	genome.wustl.edu	37	19	18392909	18392909	+	RNA	SNP	C	C	T			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	19	18392909	18392909	C	T	SNP	MIR3188	ENST00000583494	human	ensembl	74_37	1	known	rna	NULL	NULL	0	0	0	0	no_errors	0	0	0	36	0	0	17	13	43.33	56	0	0.00	26	19	42.22
EXTL3	0	genome.wustl.edu	37	8	28574610	28574611	+	Frame_Shift_Ins	INS	-	-	C			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	-	-	-	C	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	8	28574610	28574611	0	C	INS	EXTL3	ENST00000220562	human	ensembl	74_37	1	known	frame_shift_ins	c.1034_1035	p.Q346fs	1.000:1.000	pfam_Exostosin	pfam_HexNAc_Trfase_a,pfam_Exostosin	0	no_errors	0	0	0	15	0	0	17	5	22.73	199	0	0.00	118	47	28.48
C17orf85	0	genome.wustl.edu	37	17	3749489	3749489	+	Missense_Mutation	SNP	G	G	A			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	17	3749489	3749489	G	A	SNP	C17orf85	ENST00000389005	human	ensembl	74_37	-1	known	missense	c.29	p.S10L	1	NULL	pfam_DUF2414	0	no_errors	0	0	0	27	0	0	37	4	9.76	14	0	0.00	9	0	0.00
FAM230A	0	genome.wustl.edu	37	22	20710684	20710684	+	Missense_Mutation	SNP	A	A	G			TCGA-ZB-A964-01A-11D-A428-09	TCGA-ZB-A964-10A-01D-A42B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	76de3c9d-321b-4da5-977e-bbea2933acc2	eacc8687-7c30-49e0-b753-1e2eb944163f	22	20710684	20710684	A	G	SNP	FAM230A	ENST00000434783	human	ensembl	74_37	1	known	missense	c.2416	p.T806A	0	NULL	pfam_Ret-finger_pr-like_3_antisense,superfamily_Kinase-like_dom	0	no_errors	0	0	0	80	1	1.23	98	15	13.04	7	0	0.00	7	0	0.00