Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error rsID rsID_ref_var_alleles CAF normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumor_var_reads tumor_vaf normal_ref_reads_val normal_var_reads_val normal_vaf_val tumor_ref_reads_val tumor_var_reads_val tumor_vaf_val MT-CO2 0 genome.wustl.edu 37 MT 7609 7609 + Silent SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 MT 7609 7609 T C SNP MT-CO2 ENST00000361739 human ensembl 74_37 1 known silent c.24 p.G8 NULL pfam_Cyt_c_oxidase_su2_TM_dom,superfamily_Cyt_c_oxidase_su2_TM_dom,pfscan_Cyt_c_oxidase_su2_TM_dom pfam_Cyt_c_oxidase_su2_C,pfam_Cyt_c_oxidase_su2_TM_dom,superfamily_Cupredoxin,superfamily_Cyt_c_oxidase_su2_TM_dom,pfscan_Cyt_c_oxidase_su2_TM_dom,pfscan_Cyt_c_oxidase_su2_C,tigrfam_Cyt_c_oxidase_su2 0 no_errors 0 0 0 874 1 0.11 1337 834 38.31 3 0 0.00 3 2 40.00 KAL1 0 genome.wustl.edu 37 X 8522068 8522068 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 8522068 8522068 G A SNP KAL1 ENST00000262648 human ensembl 74_37 -1 known missense c.1279 p.R427C 0.898 superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pfam_Fibronectin_type3,pfam_WAP-type_4-diS_core,superfamily_Fibronectin_type3,superfamily_WAP-type_4-diS_core,smart_WAP-type_4-diS_core,smart_Fibronectin_type3,pfscan_Fibronectin_type3,prints_WAP-type_4-diS_core 0 no_errors rs371623420 G->A 0 71 0 0 60 34 36.17 209 0 0.00 159 82 34.02 WWC3 0 genome.wustl.edu 37 X 10062288 10062288 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 10062288 10062288 C T SNP WWC3 ENST00000380861 human ensembl 74_37 1 known silent c.624 p.C208 0.726 NULL superfamily_C2_dom 0 no_errors 0 0 0 63 0 0 31 10 24.39 85 0 0.00 77 36 31.86 WWC3 0 genome.wustl.edu 37 X 10104702 10104702 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 10104702 10104702 G A SNP WWC3 ENST00000380861 human ensembl 74_37 1 known silent c.2793 p.T931 0.002 NULL superfamily_C2_dom 0 no_errors 0 0 0 66 0 0 53 23 30.26 254 1 0.39 185 62 25.10 REPS2 0 genome.wustl.edu 37 X 17080625 17080625 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 17080625 17080625 T A SNP REPS2 ENST00000357277 human ensembl 74_37 1 known missense c.1179 p.N393K 0.717 NULL smart_EPS15_homology,pfscan_EF_hand_dom,pfscan_EPS15_homology 0 no_errors 0 0 0 133 0 0 71 42 36.84 251 0 0.00 169 104 38.10 SCML2 0 genome.wustl.edu 37 X 18257808 18257808 + RNA SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 18257808 18257808 T G SNP SCML2 ENST00000491988 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 140 0 0 74 35 32.11 224 0 0.00 185 65 26.00 PDHA1 0 genome.wustl.edu 37 X 19362139 19362139 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 19362139 19362139 G A SNP PDHA1 ENST00000492364 human ensembl 74_37 1 known rna NULL NULL 0.023 0 0 0 no_errors 0 0 0 10 0 0 6 5 45.45 23 0 0.00 24 8 25.00 PHEX 0 genome.wustl.edu 37 X 22051242 22051242 + Splice_Site SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 22051242 22051242 G A SNP PHEX ENST00000379374 human ensembl 74_37 1 known splice_site c.118+1 e1+1 1 0 0 0 no_errors 0 0 0 12 0 0 2 2 50 240 0 0.00 172 78 31.20 MAGEB10 0 genome.wustl.edu 37 X 27840014 27840014 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 27840014 27840014 C T SNP MAGEB10 ENST00000356790 human ensembl 74_37 1 known silent c.591 p.G197 0 pfam_MAGE,pfscan_MAGE pfam_MAGE,pfam_Melanoma_ass_antigen_N,pfscan_MAGE 0 no_errors rs374712101 C->T 0 30 0 0 15 9 37.5 202 1 0.49 134 73 35.27 NR0B1 0 genome.wustl.edu 37 X 30326504 30326504 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 30326504 30326504 C T SNP NR0B1 ENST00000378970 human ensembl 74_37 -1 known missense c.977 p.R326Q 0.786 pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt 0 no_errors 0 0 0 55 0 0 29 12 29.27 68 0 0.00 66 21 24.14 DMD 0 genome.wustl.edu 37 X 32834701 32834701 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 32834701 32834701 C A SNP DMD ENST00000357033 human ensembl 74_37 -1 known missense c.414 p.K138N 1 pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pirsf_Dystrophin/utrophin,pfscan_CH-domain pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ 0 no_errors 0 0 0 103 0 0 52 13 20 225 0 0.00 237 91 27.66 BCOR 0 genome.wustl.edu 37 X 39934419 39934419 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 39934419 39934419 C T SNP BCOR ENST00000378444 human ensembl 74_37 -1 known silent c.180 p.T60 0.012 NULL pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom 0 no_errors 0 0 0 19 0 0 4 3 42.86 153 0 0.00 142 47 24.87 MED14 0 genome.wustl.edu 37 X 40572273 40572273 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 40572273 40572273 C T SNP MED14 ENST00000324817 human ensembl 74_37 -1 known missense c.674 p.R225H 1 pfam_Mediator_Med14 pfam_Mediator_Med14 0 no_errors 0 0 0 113 0 0 64 23 26.44 291 0 0.00 225 95 29.69 TBC1D25 0 genome.wustl.edu 37 X 48419277 48419277 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 48419277 48419277 C T SNP TBC1D25 ENST00000376771 human ensembl 74_37 1 known missense c.1981 p.R661C 1 superfamily_Rab-GTPase-TBC_dom pfam_Rab-GTPase-TBC_dom,superfamily_Rab-GTPase-TBC_dom,smart_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom 0 no_errors 0 0 0 17 0 0 15 3 16.67 65 0 0.00 78 41 34.17 GRIPAP1 0 genome.wustl.edu 37 X 48840261 48840261 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 48840261 48840261 G A SNP GRIPAP1 ENST00000376441 human ensembl 74_37 -1 known nonsense c.1198 p.R400* 1 NULL superfamily_Prefoldin 0 no_errors 0 0 0 70 0 0 47 13 21.67 289 1 0.34 189 86 31.27 PRAF2 0 genome.wustl.edu 37 X 48931616 48931616 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 48931616 48931616 C T SNP PRAF2 ENST00000376390 human ensembl 74_37 -1 known missense c.31 p.A11T 0.951 pfam_Prenylated_rab_accept_PRA1 pfam_Prenylated_rab_accept_PRA1 0 no_errors 0 0 0 46 0 0 21 7 25 40 0 0.00 22 10 31.25 CCNB3 0 genome.wustl.edu 37 X 50055546 50055546 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 50055546 50055546 C T SNP CCNB3 ENST00000276014 human ensembl 74_37 1 known missense c.3337 p.R1113W 0 NULL pfam_Cyclin_N,pfam_Cyclin_C-dom,superfamily_Cyclin-like,smart_Cyclin-like 0 no_errors 0 0 0 72 0 0 24 9 26.47 220 1 0.45 185 81 30.45 SHROOM4 0 genome.wustl.edu 37 X 50438919 50438919 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 50438919 50438919 C T SNP SHROOM4 ENST00000289292 human ensembl 74_37 -1 known missense c.136 p.A46T 1 pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ pfam_ASD2,pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ 0 no_errors 0 0 0 24 0 0 12 5 29.41 172 0 0.00 107 45 29.61 FAM155B 0 genome.wustl.edu 37 X 68725182 68725182 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 68725182 68725182 C T SNP FAM155B ENST00000252338 human ensembl 74_37 1 known silent c.57 p.C19 1 NULL NULL 0 no_errors 0 0 0 23 0 0 9 4 30.77 28 0 0.00 24 3 11.11 KIF4A 0 genome.wustl.edu 37 X 69510595 69510595 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 69510595 69510595 A G SNP KIF4A ENST00000374403 human ensembl 74_37 1 known missense c.175 p.T59A 0.934 pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom 0 no_errors 0 0 0 77 0 0 35 7 16.67 193 0 0.00 174 32 15.46 GDPD2 0 genome.wustl.edu 37 X 69644872 69644872 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 69644872 69644872 G A SNP GDPD2 ENST00000453994 human ensembl 74_37 1 known missense c.38 p.R13H 1 NULL pfam_GlyceroP-diester-Pdiesterase,superfamily_PLC-like_Pdiesterase_TIM-brl 0 no_errors 0 0 0 84 0 0 48 21 30.43 71 0 0.00 43 23 34.85 XIST 0 genome.wustl.edu 37 X 73047136 73047136 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 73047136 73047136 G A SNP XIST ENST00000429829 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 33 0 0 12 18 60 138 1 0.72 90 34 27.42 ATRX 0 genome.wustl.edu 37 X 76762796 76762796 + RNA SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 76762796 76762796 A G SNP ATRX ENST00000480283 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 145 0 0 81 27 25 144 0 0.00 121 42 25.77 HDX 0 genome.wustl.edu 37 X 83724352 83724352 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 83724352 83724352 C T SNP HDX ENST00000297977 human ensembl 74_37 -1 known missense c.379 p.D127N 0.858 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom 0 no_errors 0 0 0 102 0 0 54 26 32.5 274 1 0.36 222 70 23.97 RNF128 0 genome.wustl.edu 37 X 105970576 105970576 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 105970576 105970576 A G SNP RNF128 ENST00000255499 human ensembl 74_37 1 known missense c.433 p.I145V 1 pfam_Protease-assoc_domain pfam_Protease-assoc_domain,pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING 0 no_errors 0 0 0 61 0 0 22 26 54.17 113 0 0.00 91 47 34.06 IRS4 0 genome.wustl.edu 37 X 107979451 107979451 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 107979451 107979451 C T SNP IRS4 ENST00000372129 human ensembl 74_37 -1 known missense c.124 p.A42T 1 NULL pfam_Insln_rcpt_S1,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,pfscan_Pleckstrin_homology,pfscan_Insln_rcpt_S1,prints_Insln_rcpt_S1 0 no_errors 0 0 0 50 0 0 25 14 35.9 43 0 0.00 32 18 36.00 RBMXL3 0 genome.wustl.edu 37 X 114425993 114425993 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 114425993 114425993 C T SNP RBMXL3 ENST00000424776 human ensembl 74_37 1 known silent c.1989 p.Y663 0.041 NULL pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom 0 no_errors 0 0 0 93 0 0 54 23 29.87 51 0 0.00 21 7 25.00 IL13RA1 0 genome.wustl.edu 37 X 117904509 117904509 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 117904509 117904509 G A SNP IL13RA1 ENST00000371637 human ensembl 74_37 1 known silent c.282 p.A94 0.977 NULL NULL 0 no_errors 0 0 0 49 0 0 30 10 25 71 0 0.00 67 17 20.24 KIAA1210 0 genome.wustl.edu 37 X 118217055 118217055 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 118217055 118217055 G A SNP KIAA1210 ENST00000402510 human ensembl 74_37 -1 known missense c.4877 p.P1626L 0 NULL NULL 0 no_errors 0 0 0 54 0 0 35 15 30 210 1 0.47 167 63 27.39 ARHGAP36 0 genome.wustl.edu 37 X 130215768 130215768 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 130215768 130215768 C T SNP ARHGAP36 ENST00000276211 human ensembl 74_37 1 known silent c.129 p.P43 0.007 NULL pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom 0 no_errors 0 0 0 52 0 0 13 10 43.48 162 0 0.00 126 46 26.74 FAM127A 0 genome.wustl.edu 37 X 134166467 134166467 + Silent SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134166467 134166467 T C SNP FAM127A ENST00000257013 human ensembl 74_37 1 novel silent c.54 p.P18 0 NULL NULL 0 no_errors 0 0 0 63 0 0 63 5 7.35 27 0 0.00 44 3 6.38 FAM127A 0 genome.wustl.edu 37 X 134166471 134166471 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134166471 134166471 A G SNP FAM127A ENST00000257013 human ensembl 74_37 1 novel missense c.58 p.T20A 0 NULL NULL 0 no_errors 0 0 0 63 0 0 64 5 7.25 27 0 0.00 45 3 6.25 FAM127B 0 genome.wustl.edu 37 X 134185997 134185997 + Missense_Mutation SNP A A C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A C A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134185997 134185997 A C SNP FAM127B ENST00000370775 human ensembl 74_37 -1 known missense c.142 p.S48G 0.998 NULL NULL 0 no_errors 0 0 0 101 0 0 60 12 16.67 42 0 0.00 32 4 11.11 FAM127B 0 genome.wustl.edu 37 X 134186034 134186034 + Silent SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134186034 134186034 T G SNP FAM127B ENST00000370775 human ensembl 74_37 -1 known silent c.105 p.G35 0.942 NULL NULL 0 no_errors 0 0 0 95 0 0 59 11 15.71 50 0 0.00 40 9 18.37 FAM127B 0 genome.wustl.edu 37 X 134186094 134186094 + Silent SNP G G C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G C G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134186094 134186094 G C SNP FAM127B ENST00000370775 human ensembl 74_37 -1 known silent c.45 p.P15 0.002 NULL NULL 0 no_errors 0 0 0 48 0 0 36 11 23.4 54 0 0.00 35 12 25.53 FAM127B 0 genome.wustl.edu 37 X 134186098 134186098 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134186098 134186098 C A SNP FAM127B ENST00000370775 human ensembl 74_37 -1 known missense c.41 p.G14V 0.003 NULL NULL 0 no_errors 0 0 0 45 0 0 34 11 24.44 53 0 0.00 34 12 26.09 FAM127B 0 genome.wustl.edu 37 X 134186099 134186099 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 134186099 134186099 C A SNP FAM127B ENST00000370775 human ensembl 74_37 -1 known missense c.40 p.G14W 0 NULL NULL 0 no_errors 0 0 0 44 0 0 34 11 24.44 53 0 0.00 34 12 26.09 CDR1 0 genome.wustl.edu 37 X 139865788 139865788 + Missense_Mutation SNP C C G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C G C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 139865788 139865788 C G SNP CDR1 ENST00000370532 human ensembl 74_37 -1 known missense c.744 p.K248N 0.997 NULL NULL 0 no_errors 0 0 0 147 0 0 78 29 27.1 65 0 0.00 50 15 23.08 ZFP92 0 genome.wustl.edu 37 X 152686347 152686347 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 152686347 152686347 G A SNP ZFP92 ENST00000338647 human ensembl 74_37 1 known missense c.512 p.R171H 0 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 23 0 0 12 9 42.86 104 0 0.00 69 21 23.33 MPP1 0 genome.wustl.edu 37 X 154033630 154033630 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 154033630 154033630 C T SNP MPP1 ENST00000369534 human ensembl 74_37 -1 known missense c.19 p.E7K 0.986 NULL pfam_GK/Ca_channel_bsu,pfam_PDZ,pfam_SH3_2,pfam_SH3_domain,superfamily_P-loop_NTPase,superfamily_SH3_domain,superfamily_PDZ,smart_PDZ,smart_SH3_domain,smart_GK/Ca_channel_bsu,pfscan_PDZ,pfscan_SH3_domain,pfscan_Guanylate_kin-like 0 no_errors 0 0 0 49 0 0 18 18 50 53 0 0.00 33 18 34.62 C1orf170 0 genome.wustl.edu 37 1 914707 914707 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 914707 914707 G A SNP C1orf170 ENST00000433179 human ensembl 74_37 -1 known missense c.1421 p.T474M 0 NULL NULL 0 no_errors 0 0 0 50 0 0 27 12 30.77 41 0 0.00 22 13 37.14 TTLL10-AS1 0 genome.wustl.edu 37 1 1111634 1111634 + RNA SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 1111634 1111634 G T SNP TTLL10-AS1 ENST00000379317 human ensembl 74_37 -1 known rna NULL NULL 0.973 0 0 0 no_errors 0 0 0 78 0 0 45 15 25 6 0 0.00 4 4 50.00 SLC45A1 0 genome.wustl.edu 37 1 8385928 8385928 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 8385928 8385928 G A SNP SLC45A1 ENST00000377479 human ensembl 74_37 1 known missense c.643 p.A215T 0.983 pfam_MFS,superfamily_MFS_dom_general_subst_transpt pfam_MFS,superfamily_MFS_dom_general_subst_transpt 0 no_errors 0 0 0 43 0 0 16 13 44.83 80 0 0.00 75 25 24.75 SLC45A1 0 genome.wustl.edu 37 1 8386016 8386016 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 8386016 8386016 C T SNP SLC45A1 ENST00000377479 human ensembl 74_37 1 known missense c.731 p.A244V 0.973 pfam_MFS,superfamily_MFS_dom_general_subst_transpt pfam_MFS,superfamily_MFS_dom_general_subst_transpt 0 no_errors rs150539474 C->T 0 47 0 0 37 14 27.45 86 0 0.00 69 33 32.35 SLC2A7 0 genome.wustl.edu 37 1 9085042 9085042 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 9085042 9085042 G A SNP SLC2A7 ENST00000400906 human ensembl 74_37 -1 known missense c.143 p.P48L 0.588 pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,prints_Sugar/inositol_transpt,pfscan_MFS_dom,tigrfam_Sugar/inositol_transpt 0 no_errors 0 0 0 79 1 1.25 56 16 22.22 71 0 0.00 67 38 36.19 PGD 0 genome.wustl.edu 37 1 10477498 10477498 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 10477498 10477498 C T SNP PGD ENST00000270776 human ensembl 74_37 1 known silent c.1041 p.T347 0.27 pfam_6PGDH_C,superfamily_6-PGluconate_DH_C-like,tigrfam_6PGDH_decarbox pfam_6PGDH_C,pfam_6PGDH_NADP-bd,superfamily_6-PGluconate_DH_C-like,tigrfam_6PGDH_decarbox 0 no_errors rs530138934 C->T 0.9998,0.0001997 33 0 0 20 13 39.39 50 0 0.00 68 25 26.88 MTOR 0 genome.wustl.edu 37 1 11169741 11169741 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 11169741 11169741 G A SNP MTOR ENST00000361445 human ensembl 74_37 -1 known missense c.7412 p.T2471M 0.997 superfamily_Kinase-like_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_DUF3385_TOR,pfam_Rapamycin-bd_dom,pfam_FATC,superfamily_ARM-type_fold,superfamily_Kinase-like_dom,superfamily_Rapamycin-bd_dom,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom 0 no_errors 0 0 0 86 0 0 29 15 34.09 206 0 0.00 199 82 29.18 C1orf167 0 genome.wustl.edu 37 1 11836644 11836644 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 11836644 11836644 G A SNP C1orf167 ENST00000433342 human ensembl 74_37 1 known missense c.2360 p.C787Y 0 NULL NULL 0 no_errors 0 0 0 31 0 0 22 4 15.38 46 0 0.00 44 17 27.87 CLCNKA 0 genome.wustl.edu 37 1 16355778 16355778 + Missense_Mutation SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 16355778 16355778 T G SNP CLCNKA ENST00000331433 human ensembl 74_37 1 known missense c.1211 p.F404C 1 pfam_Cl-channel_volt-gated,superfamily_Cl-channel_core pfam_Cl-channel_volt-gated,pfam_CBS_dom,superfamily_Cl-channel_core,smart_CBS_dom,prints_Cl-channel_volt-gated,prints_Cl_channel-K 0 no_errors 0 0 0 57 0 0 39 8 17.02 199 0 0.00 161 8 4.71 SDHB 0 genome.wustl.edu 37 1 17354321 17354321 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 17354321 17354321 G A SNP SDHB ENST00000375499 human ensembl 74_37 -1 known missense c.463 p.P155S 1 superfamily_Helical_ferredxn,tigrfam_Succ_DH/fum_Rdtase_Fe-S superfamily_Helical_ferredxn,superfamily_2Fe-2S_ferredoxin-type,pfscan_2Fe-2S_ferredoxin-type,tigrfam_Succ_DH/fum_Rdtase_Fe-S 0 no_errors 0 0 0 44 0 0 33 10 23.26 169 1 0.58 138 70 33.49 C1QC 0 genome.wustl.edu 37 1 22973773 22973773 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 22973773 22973773 G A SNP C1QC ENST00000374637 human ensembl 74_37 1 known missense c.235 p.G79S 0.978 pfam_Collagen pfam_C1q,pfam_Collagen,superfamily_Tumour_necrosis_fac-like_dom,smart_C1q,pfscan_C1q,prints_C1q 0 no_errors 0 0 0 46 0 0 15 14 48.28 121 0 0.00 105 42 28.57 LUZP1 0 genome.wustl.edu 37 1 23420409 23420409 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 23420409 23420409 G A SNP LUZP1 ENST00000302291 human ensembl 74_37 -1 known nonsense c.346 p.R116* 1 NULL NULL 0 no_errors 0 0 0 55 0 0 39 15 27.78 221 0 0.00 197 77 28.10 SRRM1 0 genome.wustl.edu 37 1 24979467 24979467 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 24979467 24979467 G A SNP SRRM1 ENST00000447431 human ensembl 74_37 1 known silent c.984 p.P328 0.702 NULL pfam_PWI_dom,superfamily_PWI_dom,smart_PWI_dom 0 no_errors rs142035407 G->A 1,0 123 1 0.81 80 27 25.23 39 0 0.00 29 17 36.96 CLIC4 0 genome.wustl.edu 37 1 25140616 25140616 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 25140616 25140616 G A SNP CLIC4 ENST00000374379 human ensembl 74_37 1 known missense c.214 p.G72R 1 superfamily_Thioredoxin-like_fold,tigrfam_Int_Cl_channel superfamily_Glutathione-S-Trfase_C-like,superfamily_Thioredoxin-like_fold,prints_Int_Cl_channel,tigrfam_Int_Cl_channel 0 no_errors 0 0 0 90 1 1.09 41 20 32.79 271 0 0.00 226 94 29.28 C1orf63 0 genome.wustl.edu 37 1 25573068 25573068 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 25573068 25573068 C A SNP C1orf63 ENST00000417642 human ensembl 74_37 -1 known missense c.366 p.R122S 0 NULL NULL 0 no_errors 0 0 0 47 0 0 25 8 23.53 115 0 0.00 99 42 29.79 DHDDS 0 genome.wustl.edu 37 1 26769265 26769265 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 26769265 26769265 T A SNP DHDDS ENST00000360009 human ensembl 74_37 1 known missense c.224 p.V75D 1 pfam_UPP_synth-like,superfamily_UPP_synth-like,tigrfam_UPP_synth-like pfam_UPP_synth-like,superfamily_UPP_synth-like,tigrfam_UPP_synth-like 0 no_errors 0 0 0 51 0 0 36 10 21.74 215 0 0.00 173 75 30.24 PTPRU 0 genome.wustl.edu 37 1 29585175 29585175 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 29585175 29585175 C T SNP PTPRU ENST00000345512 human ensembl 74_37 1 known missense c.364 p.R122C 1 pfam_MAM_dom,superfamily_ConA-like_lec_gl_sf,smart_MAM_dom,pfscan_MAM_dom pfam_Tyr_Pase_rcpt/non-rcpt,pfam_MAM_dom,pfam_Fibronectin_type3,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_MAM_dom,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_MAM_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt,prints_MAM_dom 0 no_errors 0 0 0 21 0 0 17 9 34.62 95 0 0.00 68 18 20.93 SLC2A1 0 genome.wustl.edu 37 1 43394959 43394959 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 43394959 43394959 G A SNP SLC2A1 ENST00000426263 human ensembl 74_37 -1 known silent c.894 p.F298 0.996 pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Sugar/inositol_transpt pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,prints_Sugar/inositol_transpt,prints_Glu_transpt_1,tigrfam_Sugar/inositol_transpt 0 no_errors rs140825318 G->A 0.9998,0.0001997 38 0 0 23 9 28.12 128 1 0.77 74 51 40.80 FAM183A 0 genome.wustl.edu 37 1 43621891 43621891 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 43621891 43621891 C T SNP FAM183A ENST00000410048 human ensembl 74_37 1 putative silent c.228 p.R76 0 NULL NULL 0 no_errors 0 0 0 42 0 0 24 6 20 153 0 0.00 96 44 31.43 ZFYVE9 0 genome.wustl.edu 37 1 52761600 52761600 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 52761600 52761600 G A SNP ZFYVE9 ENST00000287727 human ensembl 74_37 1 known missense c.3284 p.R1095Q 1 pfam_DUF3480,pirsf_Znf_FYVE_SARA/endofin pfam_DUF3480,pfam_SARA_Smad-bd,pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pirsf_Znf_FYVE_SARA/endofin,pfscan_Znf_FYVE-rel 0 no_errors 0 0 0 125 1 0.79 81 29 26.36 165 0 0.00 122 63 34.05 CC2D1B 0 genome.wustl.edu 37 1 52830227 52830227 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 52830227 52830227 C A SNP CC2D1B ENST00000371586 human ensembl 74_37 -1 known missense c.66 p.K22N 1 NULL pfam_C2_dom,superfamily_C2_dom,smart_DM14,smart_C2_dom 0 no_errors 0 0 0 55 0 0 47 8 14.55 146 0 0.00 112 63 36.00 ECHDC2 0 genome.wustl.edu 37 1 53373561 53373561 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 53373561 53373561 G A SNP ECHDC2 ENST00000371522 human ensembl 74_37 -1 known missense c.343 p.R115W 0.999 pfam_Crotonase_core_superfam pfam_Crotonase_core_superfam 0 no_errors rs200827816 G->A 0 104 1 0.94 63 34 35.05 160 0 0.00 144 59 28.37 DNAJC6 0 genome.wustl.edu 37 1 65860702 65860702 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 65860702 65860702 G A SNP DNAJC6 ENST00000371069 human ensembl 74_37 1 known silent c.2025 p.S675 0.994 NULL pfam_Tensin_phosphatase_C2-dom,pfam_DnaJ_domain,superfamily_DnaJ_domain,superfamily_C2_dom,smart_DnaJ_domain,pfscan_Tyr/Dual-sp_Pase,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom,pfscan_DnaJ_domain 0 no_errors rs185245369 G->A 0.9996,0.0003994 44 0 0 22 10 31.25 202 0 0.00 164 81 33.06 LPHN2 0 genome.wustl.edu 37 1 82456236 82456236 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 82456236 82456236 A G SNP LPHN2 ENST00000370717 human ensembl 74_37 1 known missense c.3832 p.I1278V 1 pfam_GPCR_2_latrophilin_rcpt_C pfam_GPCR_2_latrophilin_rcpt_C,pfam_Olfac-like,pfam_DUF3497,pfam_GPCR_2_secretin-like,pfam_Lectin_gal-bd_dom,pfam_GPS_dom,pfam_GPCR_2_extracellular_dom,smart_Olfac-like,smart_GPCR_2_extracellular_dom,smart_GPS_dom,prints_GPCR_2_latrophilin,prints_GPCR_2_secretin-like,pfscan_GPS_dom,pfscan_Lectin_gal-bd_dom,pfscan_Olfac-like,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like 0 no_errors 0 0 0 42 0 0 27 11 28.95 138 0 0.00 93 40 30.08 GTF2B 0 genome.wustl.edu 37 1 89318925 89318925 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 89318925 89318925 T C SNP GTF2B ENST00000370500 human ensembl 74_37 -1 known missense c.922 p.T308A 1 superfamily_Cyclin-like pfam_TFIIB_cyclin,pfam_Znf_TFIIB,pfam_Cyclin_N,superfamily_Cyclin-like,smart_Cyclin-like,pfscan_Znf_TFIIB,prints_TFIIB 0 no_errors 0 0 0 89 0 0 60 27 31.03 276 0 0.00 228 97 29.75 SLC16A1 0 genome.wustl.edu 37 1 113471876 113471876 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 113471876 113471876 C A SNP SLC16A1 ENST00000369626 human ensembl 74_37 -1 known missense c.55 p.G19C 1 superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Monocarb_transpt pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Monocarb_transpt 0 no_errors 0 0 0 58 0 0 24 22 47.83 225 1 0.44 173 61 25.96 WDR3 0 genome.wustl.edu 37 1 118483747 118483747 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 118483747 118483747 C T SNP WDR3 ENST00000349139 human ensembl 74_37 1 known nonsense c.790 p.R264* 1 superfamily_WD40_repeat_dom,pfscan_WD40_repeat_dom pfam_WD40_repeat,pfam_SSU_processome_Utp12,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep 0 no_errors 0 0 0 51 0 0 30 9 23.08 185 0 0.00 137 68 33.17 PHGDH 0 genome.wustl.edu 37 1 120263834 120263834 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 120263834 120263834 C T SNP PHGDH ENST00000369409 human ensembl 74_37 1 known silent c.180 p.T60 0.038 pfam_D-isomer_2_OHA_DH_cat_dom,tigrfam_D-3-Phosphoglycerate_DH pfam_D-isomer_2_OHA_DH_NAD-bd,pfam_D-isomer_2_OHA_DH_cat_dom,tigrfam_D-3-Phosphoglycerate_DH 0 no_errors 0 0 0 30 0 0 21 6 21.43 150 0 0.00 106 35 24.82 PDE4DIP 0 genome.wustl.edu 37 1 144874778 144874778 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 144874778 144874778 G T SNP PDE4DIP ENST00000369356 human ensembl 74_37 -1 known silent c.4830 p.T1610 0.989 NULL pfam_Spindle_assoc,superfamily_ARM-type_fold 0 no_errors 0 0 0 93 0 0 62 9 12.68 90 0 0.00 131 18 12.08 ANKRD34A 0 genome.wustl.edu 37 1 145473413 145473413 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 145473413 145473413 G A SNP ANKRD34A ENST00000323397 human ensembl 74_37 1 known missense c.85 p.A29T 1 superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom 0 no_errors 0 0 0 40 0 0 37 10 21.28 129 0 0.00 134 30 18.18 RBM8A 0 genome.wustl.edu 37 1 145509002 145509002 + Silent SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 145509002 145509002 C A SNP RBM8A ENST00000330165 human ensembl 74_37 1 known silent c.429 p.P143 0.42 pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,prints_RNA-bd_8 pfam_RRM_dom,pfam_RRM_3,smart_RRM_dom,pfscan_RRM_dom,prints_RNA-bd_8 0 no_errors 0 0 0 79 0 0 74 15 16.85 95 0 0.00 111 29 20.71 PIAS3 0 genome.wustl.edu 37 1 145581435 145581435 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 145581435 145581435 G A SNP PIAS3 ENST00000393045 human ensembl 74_37 1 known missense c.1016 p.R339H 0.997 pfam_Znf_MIZ,pfscan_Znf_MIZ pfam_Znf_MIZ,smart_SAP_dom,pfscan_Znf_MIZ,pfscan_SAP_dom 0 no_errors 0 0 0 32 0 0 41 9 18 148 0 0.00 147 38 20.54 ADAMTSL4 0 genome.wustl.edu 37 1 150532263 150532263 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 150532263 150532263 G A SNP ADAMTSL4 ENST00000369039 human ensembl 74_37 1 known silent c.3039 p.T1013 0.008 pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt pfam_ADAM_spacer1,pfam_Thrombospondin_1_rpt,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_PLAC,pfscan_Thrombospondin_1_rpt 0 no_errors rs368789447 G->A 0.9998,0.0001997 56 0 0 39 21 35 86 0 0.00 104 25 19.38 RFX5 0 genome.wustl.edu 37 1 151315023 151315023 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 151315023 151315023 C A SNP RFX5 ENST00000290524 human ensembl 74_37 -1 known missense c.1490 p.R497M 0.001 NULL pfam_DNA-bd_RFX 0 no_errors 0 0 0 36 0 0 22 4 15.38 159 0 0.00 189 37 16.37 RIIAD1 0 genome.wustl.edu 37 1 151700079 151700079 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 151700079 151700079 A G SNP RIIAD1 ENST00000479191 human ensembl 74_37 1 known missense c.190 p.I64V 0.987 pfam_cAMP_dep_PK_reg_su_I/II_a/b,superfamily_cAMP_dep_PK_reg_su_I/II_a/b pfam_cAMP_dep_PK_reg_su_I/II_a/b,superfamily_cAMP_dep_PK_reg_su_I/II_a/b 0 no_errors 0 0 0 70 0 0 42 14 24.56 203 1 0.49 232 67 22.33 FLG 0 genome.wustl.edu 37 1 152275306 152275306 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 152275306 152275306 G A SNP FLG ENST00000368799 human ensembl 74_37 -1 known missense c.12056 p.A4019V 0 NULL pfam_Filaggrin,pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom,prints_Filaggrin 0 no_errors rs372573825 G->A 0.9998,0.0001997 66 0 0 33 7 17.5 244 0 0.00 288 116 28.71 FLG 0 genome.wustl.edu 37 1 152285917 152285917 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 152285917 152285917 T C SNP FLG ENST00000368799 human ensembl 74_37 -1 known missense c.1445 p.H482R 0.002 NULL pfam_Filaggrin,pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom,prints_Filaggrin 0 no_errors 0 0 0 96 0 0 70 24 25.53 61 0 0.00 66 7 9.59 LCE3B 0 genome.wustl.edu 37 1 152586488 152586488 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 152586488 152586488 C T SNP LCE3B ENST00000335633 human ensembl 74_37 1 novel missense c.202 p.R68C 0.115 NULL NULL 0 no_errors rs201393572 C->T 0.9996,0.0003994 33 0 0 7 18 72 11 0 0.00 2 6 75.00 ASH1L 0 genome.wustl.edu 37 1 155451108 155451108 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 155451108 155451108 T C SNP ASH1L ENST00000368346 human ensembl 74_37 -1 known missense c.1553 p.K518R 1 NULL pfam_SET_dom,pfam_BAH_dom,pfam_Bromodomain,pfam_Znf_PHD-finger,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,smart_AT_hook_DNA-bd_motif,smart_AWS,smart_SET_dom,smart_Bromodomain,smart_Znf_PHD,smart_BAH_dom,pfscan_AWS,pfscan_BAH_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Bromodomain 0 no_errors 0 0 0 67 1 1.47 62 17 21.52 238 2 0.83 293 83 22.07 SEMA4A 0 genome.wustl.edu 37 1 156142758 156142758 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 156142758 156142758 C A SNP SEMA4A ENST00000355014 human ensembl 74_37 1 known missense c.1276 p.L426I 0 pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,pfscan_Semap_dom 0 no_errors 0 0 0 45 0 0 46 5 9.8 165 0 0.00 166 59 26.22 VHLL 0 genome.wustl.edu 37 1 156268898 156268898 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 156268898 156268898 T C SNP VHLL ENST00000339922 human ensembl 74_37 -1 known missense c.83 p.E28G 0.001 NULL pfam_VHL_tumour_suppress_b/a_dom,superfamily_VHL_tumour_suppress_b/a_dom 0 no_errors 0 0 0 62 1 1.59 61 15 19.74 87 0 0.00 69 30 30.30 RHBG 0 genome.wustl.edu 37 1 156351150 156351150 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 156351150 156351150 T C SNP RHBG ENST00000368246 human ensembl 74_37 1 known missense c.686 p.L229P 1 pfam_NH4_transpt_AmtB-like_dom,superfamily_NH4_transpt_AmtB-like_dom,prints_RhesusRHD pfam_NH4_transpt_AmtB-like_dom,superfamily_NH4_transpt_AmtB-like_dom,prints_RhesusRHD 0 no_errors 0 0 0 34 0 0 34 6 14.63 147 0 0.00 209 41 16.40 DEDD 0 genome.wustl.edu 37 1 161090896 161090896 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 161090896 161090896 T C SNP DEDD ENST00000472996 human ensembl 74_37 -1 known rna NULL NULL 0.142 0 0 0 no_errors 0 0 0 73 0 0 78 15 16.13 222 0 0.00 236 74 23.87 DEDD 0 genome.wustl.edu 37 1 161094036 161094036 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 161094036 161094036 G A SNP DEDD ENST00000368005 human ensembl 74_37 -1 known missense c.217 p.R73C 1 pfam_DED,superfamily_DEATH-like_dom,smart_DED,pfscan_DED pfam_DED,superfamily_DEATH-like_dom,smart_DED,pfscan_DED 0 no_errors rs151010008 G->A 0 45 0 0 27 3 10 141 0 0.00 144 40 21.74 LRRC52 0 genome.wustl.edu 37 1 165514119 165514119 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 165514119 165514119 G A SNP LRRC52 ENST00000294818 human ensembl 74_37 1 known missense c.586 p.A196T 1 NULL pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp 0 no_errors rs149365089 G->A 0 33 0 0 45 14 23.73 180 0 0.00 200 58 22.39 STX6 0 genome.wustl.edu 37 1 180971836 180971836 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 180971836 180971836 C T SNP STX6 ENST00000258301 human ensembl 74_37 -1 known missense c.206 p.S69N 1 pfam_Syntaxin-6_N,superfamily_t-SNARE pfam_Syntaxin-6_N,pfam_T_SNARE_dom,superfamily_t-SNARE,smart_T_SNARE_dom,pfscan_T_SNARE_dom 0 no_errors 0 0 0 81 0 0 72 28 28 308 0 0.00 378 120 24.05 ZNF648 0 genome.wustl.edu 37 1 182026601 182026601 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 182026601 182026601 G A SNP ZNF648 ENST00000339948 human ensembl 74_37 -1 novel missense c.545 p.T182M 0 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 79 0 0 56 24 30 167 0 0.00 152 74 32.74 SMG7 0 genome.wustl.edu 37 1 183511427 183511427 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 183511427 183511427 G T SNP SMG7 ENST00000507469 human ensembl 74_37 1 known silent c.1632 p.V544 1 NULL pfam_EST1 0 no_errors 0 0 0 33 0 0 35 10 22.22 247 0 0.00 310 68 17.99 RGL1 0 genome.wustl.edu 37 1 183854067 183854067 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 183854067 183854067 G A SNP RGL1 ENST00000304685 human ensembl 74_37 1 known missense c.1051 p.A351T 1 pfam_RasGRF_CDC25,superfamily_Ras_GEF_dom,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25 pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,pfam_Ras-assoc,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,smart_Ras-assoc,pfscan_Ras-assoc,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N 0 no_errors rs78436705 G->A 0.9998,0.0001997 40 0 0 33 10 23.26 258 0 0.00 292 66 18.44 HMCN1 0 genome.wustl.edu 37 1 186106785 186106785 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 186106785 186106785 A G SNP HMCN1 ENST00000271588 human ensembl 74_37 1 known missense c.13738 p.N4580D 0.04 pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_G2_nidogen/fibulin_G2F,pfam_EGF-like_Ca-bd_dom,pfam_Thrombospondin_1_rpt,superfamily_GFP,superfamily_Thrombospondin_1_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_Cadherin-like,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Thrombospondin_1_rpt,smart_G2_nidogen/fibulin_G2F,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_G2_nidogen/fibulin_G2F,pfscan_Thrombospondin_1_rpt,pfscan_Ig-like_dom 0 no_errors 0 0 0 37 1 2.63 30 12 28.57 300 0 0.00 278 84 23.20 PRG4 0 genome.wustl.edu 37 1 186276066 186276066 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 186276066 186276066 A G SNP PRG4 ENST00000445192 human ensembl 74_37 1 known silent c.1215 p.A405 0 NULL pfam_Somatomedin_B_dom,pfam_Hemopexin-like_repeat,superfamily_Hemopexin-like_dom,smart_Somatomedin_B_dom,smart_Hemopexin-like_repeat,prints_Somatomedin_B_chordata,pfscan_Somatomedin_B_dom 0 no_errors 0 0 0 117 0 0 100 25 19.38 61 0 0.00 88 23 18.25 PRG4 0 genome.wustl.edu 37 1 186276985 186276985 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 186276985 186276985 A T SNP PRG4 ENST00000445192 human ensembl 74_37 1 known missense c.2134 p.T712S 0.006 NULL pfam_Somatomedin_B_dom,pfam_Hemopexin-like_repeat,superfamily_Hemopexin-like_dom,smart_Somatomedin_B_dom,smart_Hemopexin-like_repeat,prints_Somatomedin_B_chordata,pfscan_Somatomedin_B_dom 0 no_errors 0 0 0 92 1 1.08 80 37 31.62 162 0 0.00 175 44 19.56 TPR 0 genome.wustl.edu 37 1 186313621 186313621 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 186313621 186313621 C T SNP TPR ENST00000367478 human ensembl 74_37 -1 known silent c.3303 p.E1101 0.99 pfam_TPR_MLP1_2 pfam_TPR_MLP1_2,superfamily_Prefoldin,superfamily_tRNA-bd_arm 0 no_errors 0 0 0 46 0 0 47 14 22.95 159 0 0.00 194 87 30.96 GLRX2 0 genome.wustl.edu 37 1 193066784 193066784 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 193066784 193066784 A G SNP GLRX2 ENST00000367440 human ensembl 74_37 -1 known missense c.293 p.V98A 0.996 pfam_Glutaredoxin,superfamily_Thioredoxin-like_fold,tigrfam_Glutaredoxin_euk/vir pfam_Glutaredoxin,superfamily_Thioredoxin-like_fold,prints_Glutaredoxin_subgr,tigrfam_Glutaredoxin_euk/vir 0 no_errors 0 0 0 85 0 0 95 29 23.39 249 0 0.00 290 102 25.95 MIR181B1 0 genome.wustl.edu 37 1 198828051 198828051 + RNA SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 198828051 198828051 T A SNP MIR181B1 ENST00000385240 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 66 0 0 40 13 24.53 218 0 0.00 232 45 16.19 CACNA1S 0 genome.wustl.edu 37 1 201016708 201016708 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 201016708 201016708 C A SNP CACNA1S ENST00000362061 human ensembl 74_37 -1 known missense c.4488 p.K1496N 1 NULL pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,prints_VDCCAlpha1,prints_VDCC_L_a1su,prints_VDCC_L_a1ssu 0 no_errors 0 0 0 23 0 0 22 9 29.03 184 0 0.00 172 36 17.22 KLHL12 0 genome.wustl.edu 37 1 202861669 202861669 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 202861669 202861669 C T SNP KLHL12 ENST00000435533 human ensembl 74_37 -1 known missense c.1813 p.E605K 1 smart_Kelch_1,pirsf_Kelch-like_gigaxonin pfam_Kelch_1,pfam_BACK,pfam_BTB_POZ,pfam_Kelch_2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like 0 no_errors 0 0 0 55 0 0 47 7 12.96 61 0 0.00 66 12 15.38 ATP2B4 0 genome.wustl.edu 37 1 203682357 203682357 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 203682357 203682357 C A SNP ATP2B4 ENST00000357681 human ensembl 74_37 1 known missense c.2276 p.T759N 1 pfam_HAD-like_dom,superfamily_HAD-like_dom,tigrfam_ATPase_P-typ_Ca-transp_plasma,tigrfam_Cation_transp_P_typ_ATPase pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_cation-transptr_C,pfam_ATP_Ca_trans_C,pfam_HAD-like_dom,pfam_ATPase_P-typ_cation-transptr_N,superfamily_ATPase_P-typ_cyto_domN,superfamily_HAD-like_dom,smart_ATPase_P-typ_cation-transptr_N,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Ca-transp_plasma,tigrfam_Cation_transp_P_typ_ATPase 0 no_errors 0 0 0 48 0 0 37 9 19.15 138 0 0.00 187 56 23.05 KISS1 0 genome.wustl.edu 37 1 204159762 204159762 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 204159762 204159762 G T SNP KISS1 ENST00000367194 human ensembl 74_37 -1 known silent c.267 p.P89 0 NULL NULL 0 no_errors 0 0 0 12 0 0 10 5 33.33 15 0 0.00 10 2 16.67 LRRN2 0 genome.wustl.edu 37 1 204588191 204588191 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 204588191 204588191 G A SNP LRRN2 ENST00000367175 human ensembl 74_37 -1 known silent c.930 p.P310 0.319 smart_Leu-rich_rpt_typical-subtyp pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom 0 no_errors 0 0 0 26 0 0 27 6 17.65 194 0 0.00 206 64 23.70 TMCC2 0 genome.wustl.edu 37 1 205238455 205238455 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 205238455 205238455 C T SNP TMCC2 ENST00000358024 human ensembl 74_37 1 known silent c.1125 p.D375 0.903 pfam_Predicted_TM_coiled-coil_2 pfam_Predicted_TM_coiled-coil_2,superfamily_t-SNARE 0 no_errors 0 0 0 18 0 0 35 8 18.6 57 0 0.00 50 18 26.47 AVPR1B 0 genome.wustl.edu 37 1 206225276 206225276 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 206225276 206225276 C T SNP AVPR1B ENST00000367126 human ensembl 74_37 1 known missense c.836 p.T279I 1 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfscan_GPCR_Rhodpsn_7TM,prints_Vasoprsn_rcpt,prints_GPCR_Rhodpsn pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfscan_GPCR_Rhodpsn_7TM,prints_Vprs_rcpt_V1B,prints_Vasoprsn_rcpt,prints_GPCR_Rhodpsn,prints_Vprs_V1A_rcpt 0 no_errors 0 0 0 20 0 0 12 4 25 109 0 0.00 120 37 23.57 PLXNA2 0 genome.wustl.edu 37 1 208216462 208216462 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 208216462 208216462 C T SNP PLXNA2 ENST00000367033 human ensembl 74_37 -1 known missense c.3961 p.A1321T 1 pfam_Plexin_cytoplasmic_RasGAP_dom pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom 0 no_errors 0 0 0 77 0 0 39 20 33.9 173 0 0.00 189 64 25.30 PLXNA2 0 genome.wustl.edu 37 1 208219374 208219374 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 208219374 208219374 C T SNP PLXNA2 ENST00000367033 human ensembl 74_37 -1 known missense c.3344 p.R1115H 0.998 superfamily_Ig_E-set,smart_IPT pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom 0 no_errors 0 0 0 48 0 0 30 7 18.92 200 0 0.00 222 41 15.41 DIEXF 0 genome.wustl.edu 37 1 210024584 210024584 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 210024584 210024584 A G SNP DIEXF ENST00000491415 human ensembl 74_37 1 known missense c.2063 p.Y688C 1 pfam_Digest_organ_expansion_fac-prd pfam_Digest_organ_expansion_fac-prd,superfamily_P-loop_NTPase 0 no_errors 0 0 0 68 0 0 32 13 28.89 187 0 0.00 207 66 24.18 DTL 0 genome.wustl.edu 37 1 212273860 212273860 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 212273860 212273860 T C SNP DTL ENST00000366991 human ensembl 74_37 1 known missense c.1528 p.S510P 0.833 NULL pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 14 0 0 18 3 14.29 232 0 0.00 267 73 21.47 C1orf65 0 genome.wustl.edu 37 1 223568377 223568377 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 223568377 223568377 C T SNP C1orf65 ENST00000366875 human ensembl 74_37 1 known silent c.1560 p.H520 0 NULL NULL 0 no_errors 0 0 0 27 0 0 19 11 36.67 85 0 0.00 119 39 24.68 ACBD3 0 genome.wustl.edu 37 1 226352529 226352529 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 226352529 226352529 G A SNP ACBD3 ENST00000366812 human ensembl 74_37 -1 known missense c.530 p.A177V 0.581 NULL pfam_Acyl-CoA-binding_protein,superfamily_GOLD,superfamily_Acyl-CoA-binding_protein,pfscan_GOLD 0 no_errors 0 0 0 74 0 0 55 13 18.84 319 0 0.00 341 108 24.05 URB2 0 genome.wustl.edu 37 1 229771119 229771119 + Silent SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 229771119 229771119 C A SNP URB2 ENST00000258243 human ensembl 74_37 1 known silent c.759 p.S253 0.977 NULL pfam_Urb2/Npa2_C 0 no_errors 0 0 0 39 0 0 22 4 15.38 186 1 0.53 208 59 22.10 PCNXL2 0 genome.wustl.edu 37 1 233296104 233296104 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 233296104 233296104 G A SNP PCNXL2 ENST00000258229 human ensembl 74_37 -1 known missense c.3442 p.R1148C 1 NULL pfam_Pecanex,superfamily_Trypsin-like_Pept_dom 0 no_errors 0 0 0 44 0 0 44 16 26.67 135 0 0.00 184 32 14.75 KIAA1804 0 genome.wustl.edu 37 1 233497906 233497906 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 233497906 233497906 C T SNP KIAA1804 ENST00000366624 human ensembl 74_37 1 known silent c.1419 p.D473 1 pirsf_MAPKKK9/10/11 pirsf_MAPKKK9/10/11,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH3_domain,pfam_SH3_2,superfamily_Kinase-like_dom,superfamily_SH3_domain,smart_SH3_domain,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH3_domain,pfscan_SH3_domain,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 47 0 0 42 12 22.22 151 0 0.00 171 54 24.00 TARBP1 0 genome.wustl.edu 37 1 234561467 234561467 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 234561467 234561467 C T SNP TARBP1 ENST00000040877 human ensembl 74_37 -1 novel missense c.3396 p.M1132I 0.179 superfamily_ARM-type_fold pfam_SpoU_MeTrfase,superfamily_ARM-type_fold 0 no_errors 0 0 0 109 0 0 109 36 24.83 295 0 0.00 307 77 20.05 ZP4 0 genome.wustl.edu 37 1 238053867 238053867 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 238053867 238053867 A G SNP ZP4 ENST00000366570 human ensembl 74_37 -1 known silent c.69 p.P23 0 NULL pfam_ZP_dom,pfam_P_trefoil,superfamily_P_trefoil,smart_P_trefoil,smart_ZP_dom,pfscan_ZP_dom,prints_ZP_dom 0 no_errors 0 0 0 24 0 0 19 5 20.83 100 0 0.00 102 25 19.38 SH3BP5L 0 genome.wustl.edu 37 1 249106496 249106496 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 249106496 249106496 C T SNP SH3BP5L ENST00000366472 human ensembl 74_37 -1 known missense c.785 p.R262H 1 pfam_SH3-bd_5 pfam_SH3-bd_5 0 no_errors 0 0 0 33 0 0 19 2 9.52 99 0 0.00 117 26 18.18 TPO 0 genome.wustl.edu 37 2 1437290 1437290 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 1437290 1437290 T A SNP TPO ENST00000329066 human ensembl 74_37 1 known missense c.260 p.I87N 0.136 NULL pfam_Haem_peroxidase_animal,pfam_EGF-like_Ca-bd_dom,superfamily_Haem_peroxidase,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Sushi_SCR_CCP,pfscan_Haem_peroxidase_animal,prints_Haem_peroxidase_animal_subgr 0 no_errors 0 0 0 55 0 0 46 17 26.98 211 0 0.00 158 70 30.70 MYT1L 0 genome.wustl.edu 37 2 1914112 1914112 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 1914112 1914112 C T SNP MYT1L ENST00000399161 human ensembl 74_37 -1 known missense c.1717 p.G573R 1 pfam_Znf_C2HC pfam_Myelin_TF,pfam_Znf_C2HC 0 no_errors 0 0 0 54 0 0 22 16 42.11 112 0 0.00 87 39 30.95 LINC00299 0 genome.wustl.edu 37 2 8439870 8439870 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 8439870 8439870 C T SNP LINC00299 ENST00000430192 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 63 0 0 38 12 24 177 1 0.56 130 62 32.12 NT5C1B 0 genome.wustl.edu 37 2 18765849 18765849 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 18765849 18765849 G A SNP NT5C1B ENST00000406971 human ensembl 74_37 -1 known missense c.587 p.T196M 0 NULL NULL 0 no_errors 0 0 0 22 0 0 21 7 25 45 0 0.00 23 15 39.47 NT5C1B 0 genome.wustl.edu 37 2 18766070 18766070 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 18766070 18766070 G A SNP NT5C1B ENST00000359846 human ensembl 74_37 -1 known missense c.613 p.R205C 0.695 NULL pfam_5-nucleotidase 0 no_errors 0 0 0 69 0 0 34 21 38.18 75 0 0.00 60 29 32.58 GAREML 0 genome.wustl.edu 37 2 26410768 26410768 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 26410768 26410768 C T SNP GAREML ENST00000401533 human ensembl 74_37 1 known missense c.2267 p.P756L 0.888 NULL superfamily_SAM/pointed 0 no_errors 0 0 0 62 0 0 39 22 36.07 95 0 0.00 89 30 25.21 OTOF 0 genome.wustl.edu 37 2 26700330 26700330 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 26700330 26700330 C T SNP OTOF ENST00000272371 human ensembl 74_37 -1 known missense c.2360 p.R787H 0.944 NULL pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom 0 no_errors 0 0 0 40 0 0 15 10 40 87 0 0.00 62 23 26.74 KCNK3 0 genome.wustl.edu 37 2 26950774 26950774 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 26950774 26950774 G A SNP KCNK3 ENST00000302909 human ensembl 74_37 1 known missense c.523 p.A175T 1 pfam_2pore_dom_K_chnl_dom,pirsf_2pore_dom_K_chnl_TASK pfam_2pore_dom_K_chnl_dom,pirsf_2pore_dom_K_chnl_TASK,prints_2pore_dom_K_chnl_TASK,prints_KCNK3,prints_2pore_dom_K_chnl 0 no_errors 0 0 0 15 0 0 15 5 25 15 0 0.00 13 7 35.00 AGBL5 0 genome.wustl.edu 37 2 27281449 27281449 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 27281449 27281449 G A SNP AGBL5 ENST00000360131 human ensembl 74_37 1 known missense c.1853 p.R618Q 0.215 NULL pfam_Peptidase_M14 0 no_errors 0 0 0 31 0 0 7 5 41.67 222 0 0.00 164 79 32.51 EMILIN1 0 genome.wustl.edu 37 2 27306067 27306067 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 27306067 27306067 A G SNP EMILIN1 ENST00000380320 human ensembl 74_37 1 known missense c.1628 p.Q543R 0.266 NULL pfam_EMI_domain,pfam_C1q,pfam_Collagen,superfamily_Tumour_necrosis_fac-like_dom,smart_C1q,pfscan_C1q,pfscan_EMI_domain 0 no_errors 0 0 0 89 0 0 58 18 23.68 76 0 0.00 71 23 24.47 CGREF1 0 genome.wustl.edu 37 2 27327327 27327327 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 27327327 27327327 G A SNP CGREF1 ENST00000404694 human ensembl 74_37 -1 novel missense c.274 p.R92C 0 NULL pfscan_EF_hand_dom 0 no_errors 0 0 0 41 0 0 24 5 17.24 137 0 0.00 97 35 26.52 FAM98A 0 genome.wustl.edu 37 2 33810307 33810307 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 33810307 33810307 C A SNP FAM98A ENST00000238823 human ensembl 74_37 -1 known missense c.1093 p.G365C 0.979 NULL pfam_Uncharacterised_FAM98 0 no_errors 0 0 0 40 0 0 24 5 17.24 134 0 0.00 130 61 31.94 PPP1R21 0 genome.wustl.edu 37 2 48741958 48741958 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 48741958 48741958 G A SNP PPP1R21 ENST00000476199 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 43 0 0 31 4 11.43 111 0 0.00 86 28 24.56 PSME4 0 genome.wustl.edu 37 2 54163925 54163925 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 54163925 54163925 C T SNP PSME4 ENST00000404125 human ensembl 74_37 -1 known silent c.735 p.V245 0.998 NULL pfam_DUF3437,superfamily_ARM-type_fold 0 no_errors 0 0 0 308 0 0 190 79 29.37 273 0 0.00 220 103 31.79 DYSF 0 genome.wustl.edu 37 2 71825779 71825779 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 71825779 71825779 G A SNP DYSF ENST00000413539 human ensembl 74_37 1 known silent c.3699 p.T1233 0.065 pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,pfam_Ferlin_A-domain,superfamily_C2_dom,superfamily_MFS_dom_general_subst_transpt,smart_C2_dom,smart_Peroxin/Ferlin,pfscan_C2_dom 0 no_errors rs139897804 G->A 0 29 0 0 19 9 32.14 163 0 0.00 155 69 30.67 TET3 0 genome.wustl.edu 37 2 74274650 74274650 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 74274650 74274650 C T SNP TET3 ENST00000409262 human ensembl 74_37 1 known missense c.1201 p.R401C 1 NULL NULL 0 no_errors 0 0 0 33 0 0 20 10 33.33 111 0 0.00 72 23 24.21 SLC4A5 0 genome.wustl.edu 37 2 74474314 74474314 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 74474314 74474314 G A SNP SLC4A5 ENST00000357822 human ensembl 74_37 -1 known silent c.1908 p.T636 0.026 pfam_HCO3_transpt_C,prints_HCO3_transpt_euk,tigrfam_HCO3_transpt_euk pfam_HCO3_transpt_C,pfam_Band3_cytoplasmic_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk,prints_Na/HCO3_transpt,tigrfam_HCO3_transpt_euk 0 no_errors 0 0 0 39 0 0 33 8 19.51 140 0 0.00 101 32 23.88 SLC4A5 0 genome.wustl.edu 37 2 74512935 74512935 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 74512935 74512935 A G SNP SLC4A5 ENST00000357822 human ensembl 74_37 -1 known silent c.366 p.H122 0.455 superfamily_PTrfase/Anion_transptr,tigrfam_HCO3_transpt_euk pfam_HCO3_transpt_C,pfam_Band3_cytoplasmic_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk,prints_Na/HCO3_transpt,tigrfam_HCO3_transpt_euk 0 no_errors 0 0 0 35 0 0 12 6 33.33 75 0 0.00 66 34 34.00 TCF7L1 0 genome.wustl.edu 37 2 85532524 85532524 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 85532524 85532524 C T SNP TCF7L1 ENST00000282111 human ensembl 74_37 1 known silent c.987 p.S329 1 superfamily_HMG_box_dom pfam_CTNNB1-bd_N,pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom 0 no_errors 0 0 0 37 0 0 16 14 46.67 90 0 0.00 45 17 27.42 POLR1A 0 genome.wustl.edu 37 2 86325826 86325826 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 86325826 86325826 G A SNP POLR1A ENST00000263857 human ensembl 74_37 -1 known missense c.340 p.R114W 0.998 pfam_RNA_pol_Rpb1_1 pfam_RNA_pol_Rpb1_5,pfam_RNA_pol_asu,pfam_RNA_pol_Rpb1_3,pfam_RNA_pol_Rpb1_4,pfam_RNA_pol_Rpb1_1,smart_RNA_pol_N 0 no_errors 0 0 0 42 0 0 45 18 28.57 156 0 0.00 154 57 26.76 EIF5B 0 genome.wustl.edu 37 2 100009524 100009524 + Missense_Mutation SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 100009524 100009524 T G SNP EIF5B ENST00000289371 human ensembl 74_37 1 known missense c.2843 p.L948R 1 NULL pfam_EF_GTP-bd_dom,pfam_TIF_IF2_dom3,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Transl_B-barrel,superfamily_TIF_IF2_dom3,prints_EF_GTP-bd_dom,tigrfam_Small_GTP-bd_dom 0 no_errors 0 0 0 296 0 0 148 54 26.6 291 0 0.00 224 88 28.21 RGPD4 0 genome.wustl.edu 37 2 108443524 108443524 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 108443524 108443524 G A SNP RGPD4 ENST00000354986 human ensembl 74_37 1 known missense c.55 p.A19T 0.521 NULL pfam_Ran_bind_dom,pfam_GRIP,pfam_TPR_1,pfam_TPR_2,superfamily_GRIP,smart_TPR_repeat,smart_Ran_bind_dom,smart_GRIP,pfscan_GRIP,pfscan_TPR_repeat,pfscan_TPR-contain_dom,pfscan_Ran_bind_dom 0 no_errors 0 0 0 122 0 0 63 35 35.71 12 0 0.00 14 3 17.65 MERTK 0 genome.wustl.edu 37 2 112751863 112751863 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 112751863 112751863 C T SNP MERTK ENST00000295408 human ensembl 74_37 1 known silent c.1332 p.S444 0.944 superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Rhodanese-like_dom,smart_Ig_sub,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_Ser-Thr/Tyr_kinase_cat_dom 0 no_errors 0 0 0 41 0 0 23 8 25.81 142 1 0.70 110 53 32.52 MERTK 0 genome.wustl.edu 37 2 112786161 112786161 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 112786161 112786161 C T SNP MERTK ENST00000295408 human ensembl 74_37 1 known missense c.2720 p.T907I 0 superfamily_Rhodanese-like_dom pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Rhodanese-like_dom,smart_Ig_sub,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_Ser-Thr/Tyr_kinase_cat_dom 0 no_errors rs202205484 C->T 0.9998,0.0001997 37 0 0 23 5 17.86 103 0 0.00 111 24 17.78 WDR33 0 genome.wustl.edu 37 2 128467396 128467396 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 128467396 128467396 G A SNP WDR33 ENST00000322313 human ensembl 74_37 -1 known missense c.3343 p.R1115C 1 NULL pfam_WD40_repeat,pfam_Collagen,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 29 0 0 14 11 44 160 0 0.00 128 48 27.27 MAP3K19 0 genome.wustl.edu 37 2 135744355 135744355 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 135744355 135744355 C T SNP MAP3K19 ENST00000375845 human ensembl 74_37 -1 known missense c.2087 p.R696H 0.032 NULL pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors rs368406495 C->T 0 60 0 0 34 24 41.38 208 0 0.00 179 55 23.50 SCN3A 0 genome.wustl.edu 37 2 165947440 165947440 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 165947440 165947440 A G SNP SCN3A ENST00000283254 human ensembl 74_37 -1 known silent c.5223 p.C1741 0.999 pfam_Ion_trans_dom,pfam_PKD1_2_channel pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,pfscan_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2 0 no_errors 0 0 0 93 0 0 58 9 13.43 129 0 0.00 95 48 33.33 LOC100130256 0 genome.wustl.edu 37 2 171538994 171538994 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 171538994 171538994 G A SNP LOC100130256 ENST00000428156 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 59 0 0 33 17 33.33 179 0 0.00 186 77 29.28 EVX2 0 genome.wustl.edu 37 2 176947101 176947101 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 176947101 176947101 G A SNP EVX2 ENST00000308618 human ensembl 74_37 -1 known silent c.504 p.G168 1 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Antifreeze_1,prints_Homeobox_metazoa 0 no_errors 0 0 0 14 0 0 6 3 33.33 13 0 0.00 16 2 11.11 PRKRA 0 genome.wustl.edu 37 2 179300872 179300872 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 179300872 179300872 C A SNP PRKRA ENST00000325748 human ensembl 74_37 -1 known missense c.784 p.D262Y 1 smart_dsRNA-bd_dom,pfscan_dsRNA-bd_dom pfam_dsRNA-bd_dom,smart_dsRNA-bd_dom,pfscan_dsRNA-bd_dom 0 no_errors 0 0 0 99 0 0 41 25 37.88 277 0 0.00 232 70 23.10 CCDC150 0 genome.wustl.edu 37 2 197565893 197565893 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 197565893 197565893 G A SNP CCDC150 ENST00000389175 human ensembl 74_37 1 known missense c.1684 p.G562R 0.997 NULL NULL 0 no_errors rs200176761 G->A 0 161 1 0.62 87 24 21.62 303 0 0.00 261 113 30.13 PTH2R 0 genome.wustl.edu 37 2 209315497 209315497 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 209315497 209315497 G A SNP PTH2R ENST00000272847 human ensembl 74_37 1 known missense c.877 p.A293T 0.989 pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like 0 no_errors 0 0 0 91 0 0 53 15 22.06 161 0 0.00 119 48 28.74 ITM2C 0 genome.wustl.edu 37 2 231741651 231741651 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 231741651 231741651 G A SNP ITM2C ENST00000326427 human ensembl 74_37 1 known missense c.530 p.R177H 0.915 pfam_BRICHOS_dom,pfscan_BRICHOS_dom pfam_BRICHOS_dom,pfscan_BRICHOS_dom 0 no_errors rs199999372 G->A 0 32 0 0 19 6 24 131 1 0.76 140 37 20.90 ALPPL2 0 genome.wustl.edu 37 2 233274420 233274420 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 233274420 233274420 C T SNP ALPPL2 ENST00000295453 human ensembl 74_37 1 known silent c.1437 p.H479 0.997 pfam_Alkaline_phosphatase,superfamily_Alkaline_phosphatase_core,smart_Alkaline_phosphatase pfam_Alkaline_phosphatase,superfamily_Alkaline_phosphatase_core,smart_Alkaline_phosphatase,prints_Alkaline_phosphatase 0 no_errors 0 0 0 32 0 0 16 5 23.81 29 0 0.00 20 10 33.33 DNAJB3 0 genome.wustl.edu 37 2 234652110 234652110 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 234652110 234652110 C T SNP DNAJB3 ENST00000449667 human ensembl 74_37 -1 known rna NULL NULL 0.002 0 0 0 no_errors rs542057655 C->T 0 44 0 0 24 12 33.33 120 0 0.00 70 24 25.53 AGAP1 0 genome.wustl.edu 37 2 236653408 236653408 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 236653408 236653408 G A SNP AGAP1 ENST00000304032 human ensembl 74_37 1 known missense c.463 p.V155I 0.994 pfam_MIRO-like,pfam_Small_GTPase,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type pfam_ArfGAP,pfam_MIRO-like,pfam_Small_GTPase,pfam_Ankyrin_rpt,pfam_Pleckstrin_homology,superfamily_P-loop_NTPase,superfamily_Ankyrin_rpt-contain_dom,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Pleckstrin_homology,smart_ArfGAP,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Pleckstrin_homology,pfscan_ArfGAP,prints_ArfGAP,prints_Small_GTPase 0 no_errors rs200676786 G->A 0 71 0 0 45 22 32.84 180 0 0.00 141 46 24.60 LOC151174 0 genome.wustl.edu 37 2 239133835 239133835 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 239133835 239133835 G A SNP LOC151174 ENST00000334973 human ensembl 74_37 -1 known missense c.371 p.A124V 0.017 NULL NULL 0 no_errors rs575876157 G->A 0 70 0 0 35 15 30 168 0 0.00 130 45 25.71 ING5 0 genome.wustl.edu 37 2 242648685 242648685 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 242648685 242648685 C T SNP ING5 ENST00000313552 human ensembl 74_37 1 known missense c.164 p.T55M 0.725 NULL pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,pfscan_Znf_PHD-finger 0 no_errors 0 0 0 25 0 0 12 5 29.41 101 0 0.00 61 28 31.46 CCDC174 0 genome.wustl.edu 37 3 14711556 14711556 + Silent SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 14711556 14711556 T C SNP CCDC174 ENST00000383794 human ensembl 74_37 1 known silent c.1068 p.P356 0.023 NULL NULL 0 no_errors 0 0 0 30 0 0 8 10 55.56 165 0 0.00 68 65 48.51 EFHB 0 genome.wustl.edu 37 3 19924092 19924092 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 19924092 19924092 G A SNP EFHB ENST00000295824 human ensembl 74_37 -1 known missense c.2278 p.R760W 0.964 NULL pfam_SPARC/Testican_Ca-bd-dom,smart_EF_hand_dom,pfscan_EF_hand_dom 0 no_errors 0 0 0 97 0 0 20 23 53.49 248 0 0.00 124 95 43.38 MLH1 0 genome.wustl.edu 37 3 37035147 37035147 + Nonsense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 37035147 37035147 G T SNP MLH1 ENST00000231790 human ensembl 74_37 1 known nonsense c.109 p.E37* 1 pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,tigrfam_DNA_mismatch_repair_N pfam_DNA_mismatch_repair_C,pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,tigrfam_DNA_mismatch_repair_N 0 no_errors rs63751012 G->A,T 0 111 0 0 32 17 34.69 101 0 0.00 59 40 40.40 SLC22A13 0 genome.wustl.edu 37 3 38307356 38307356 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 38307356 38307356 C T SNP SLC22A13 ENST00000311856 human ensembl 74_37 1 known missense c.5 p.A2V 0.695 superfamily_MFS_dom_general_subst_transpt pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom 0 no_errors 0 0 0 50 1 1.96 17 8 32 213 0 0.00 91 63 40.91 TGM4 0 genome.wustl.edu 37 3 44935086 44935086 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 44935086 44935086 C T SNP TGM4 ENST00000296125 human ensembl 74_37 1 known missense c.448 p.P150S 0.073 NULL pfam_Transglutaminase_N,pfam_Transglutaminase_C,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like 0 no_errors 0 0 0 29 0 0 6 6 50 119 0 0.00 66 41 38.32 SETD2 0 genome.wustl.edu 37 3 47142960 47142960 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 47142960 47142960 A G SNP SETD2 ENST00000409792 human ensembl 74_37 -1 known missense c.5003 p.F1668S 1 smart_SET_dom,pfscan_SET_dom pfam_SRI,pfam_SET_dom,pfam_WW_dom,superfamily_WW_dom,superfamily_Ferritin-like_SF,smart_AWS,smart_SET_dom,smart_Post-SET_dom,smart_WW_dom,pfscan_AWS,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_WW_dom 0 no_errors 0 0 0 359 0 0 126 82 39.42 294 0 0.00 167 111 39.93 PLXNB1 0 genome.wustl.edu 37 3 48465012 48465012 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 48465012 48465012 G A SNP PLXNB1 ENST00000296440 human ensembl 74_37 -1 known nonsense c.1009 p.R337* 0.956 pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_IPT,pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom 0 no_errors 0 0 0 49 0 0 14 12 46.15 86 0 0.00 30 12 28.57 CACNA2D2 0 genome.wustl.edu 37 3 50425016 50425016 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 50425016 50425016 T C SNP CACNA2D2 ENST00000435965 human ensembl 74_37 -1 known missense c.493 p.K165E 1 pfam_VWA_N pfam_VWA_N,pfam_VDCC_a2/dsu,pfam_Cache_domain,pfam_VWF_A,smart_VWF_A,pfscan_VWF_A 0 no_errors 0 0 0 23 0 0 6 5 45.45 128 0 0.00 50 44 46.81 MTHFD2P1 0 genome.wustl.edu 37 3 95373487 95373487 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 95373487 95373487 G A SNP MTHFD2P1 ENST00000494840 human ensembl 74_37 -1 known rna NULL NULL 0.01 0 0 0 no_errors 0 0 0 21 0 0 18 3 14.29 257 0 0.00 194 73 27.14 TRAT1 0 genome.wustl.edu 37 3 108566012 108566012 + RNA SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 108566012 108566012 A G SNP TRAT1 ENST00000493604 human ensembl 74_37 1 known rna NULL NULL 0.002 0 0 0 no_errors 0 0 0 136 0 0 105 36 25.53 314 0 0.00 391 108 21.64 BOC 0 genome.wustl.edu 37 3 112992057 112992057 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 112992057 112992057 G A SNP BOC ENST00000273395 human ensembl 74_37 1 known missense c.1103 p.R368H 1 pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom 0 no_errors 0 0 0 20 0 0 12 6 33.33 53 0 0.00 59 19 24.36 SPICE1 0 genome.wustl.edu 37 3 113187079 113187079 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 113187079 113187079 G A SNP SPICE1 ENST00000295872 human ensembl 74_37 -1 known silent c.1062 p.R354 0.028 NULL NULL 0 no_errors 0 0 0 26 0 0 20 5 19.23 224 0 0.00 229 51 18.15 ARHGAP31 0 genome.wustl.edu 37 3 119134183 119134183 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 119134183 119134183 A G SNP ARHGAP31 ENST00000264245 human ensembl 74_37 1 known missense c.3407 p.E1136G 0.185 NULL pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom 0 no_errors 0 0 0 33 0 0 20 8 28.57 149 0 0.00 186 44 19.05 POLQ 0 genome.wustl.edu 37 3 121208594 121208594 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 121208594 121208594 C T SNP POLQ ENST00000264233 human ensembl 74_37 -1 known missense c.3184 p.A1062T 0 NULL pfam_DNA-dir_DNA_pol_A_palm_dom,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_RNaseH-like_dom,smart_Helicase_ATP-bd,smart_Helicase_C,smart_DNA-dir_DNA_pol_A_palm_dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,prints_DNA_polymerase_A 0 no_errors 0 0 0 38 0 0 47 13 21.67 236 0 0.00 347 94 21.32 GOLGB1 0 genome.wustl.edu 37 3 121448891 121448891 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 121448891 121448891 T C SNP GOLGB1 ENST00000472829 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 57 0 0 50 7 12.28 260 0 0.00 351 113 24.30 IQCB1 0 genome.wustl.edu 37 3 121500719 121500719 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 121500719 121500719 C T SNP IQCB1 ENST00000310864 human ensembl 74_37 -1 known silent c.1281 p.A427 0.882 superfamily_P-loop_NTPase pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS 0 no_errors rs201319850 C->T 0 96 0 0 71 19 21.11 273 1 0.36 317 68 17.62 SEMA5B 0 genome.wustl.edu 37 3 122634326 122634326 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 122634326 122634326 T A SNP SEMA5B ENST00000451055 human ensembl 74_37 -1 known missense c.2111 p.D704V 0.163 superfamily_Thrombospondin_1_rpt pfam_Semap_dom,pfam_Thrombospondin_1_rpt,superfamily_Semap_dom,superfamily_Thrombospondin_1_rpt,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_Thrombospondin_1_rpt,pfscan_Semap_dom,pfscan_Thrombospondin_1_rpt 0 no_errors 0 0 0 27 0 0 23 5 17.86 108 0 0.00 114 15 11.63 ADCY5 0 genome.wustl.edu 37 3 123008708 123008708 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 123008708 123008708 C T SNP ADCY5 ENST00000462833 human ensembl 74_37 -1 known missense c.3421 p.D1141N 1 pfam_A/G_cyclase,superfamily_A/G_cyclase,smart_A/G_cyclase,pfscan_A/G_cyclase pfam_A/G_cyclase,pfam_Adenylate_cyclase-like,superfamily_A/G_cyclase,smart_A/G_cyclase,pfscan_A/G_cyclase 0 no_errors 0 0 0 37 0 0 26 9 25.71 139 0 0.00 122 38 23.75 KLF15 0 genome.wustl.edu 37 3 126071428 126071428 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 126071428 126071428 G A SNP KLF15 ENST00000296233 human ensembl 74_37 -1 known missense c.338 p.A113V 0.001 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 18 0 0 13 5 27.78 130 0 0.00 127 37 22.56 PLXNA1 0 genome.wustl.edu 37 3 126708480 126708480 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 126708480 126708480 C T SNP PLXNA1 ENST00000393409 human ensembl 74_37 1 known silent c.1044 p.R348 0.017 pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom 0 no_errors rs373912187 C->T 0 52 0 0 43 10 18.87 115 0 0.00 106 44 29.33 RPN1 0 genome.wustl.edu 37 3 128363786 128363786 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 128363786 128363786 C T SNP RPN1 ENST00000296255 human ensembl 74_37 -1 known missense c.302 p.R101H 0.987 pfam_Ribophorin_I pfam_Ribophorin_I 0 no_errors rs199783080 C->T 0.9998,0.0001997 139 0 0 111 28 20.14 340 1 0.29 384 92 19.33 HMCES 0 genome.wustl.edu 37 3 129007805 129007805 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 129007805 129007805 C T SNP HMCES ENST00000383463 human ensembl 74_37 1 known missense c.292 p.R98C 1 pfam_DUF159,superfamily_DUF159 pfam_DUF159,superfamily_DUF159 0 no_errors 0 0 0 114 1 0.87 70 28 28.57 216 0 0.00 263 76 22.42 COL6A5 0 genome.wustl.edu 37 3 130187649 130187649 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 130187649 130187649 T A SNP COL6A5 ENST00000265379 human ensembl 74_37 1 known missense c.6801 p.N2267K 0.034 NULL pfam_VWF_A,pfam_Collagen,smart_VWF_A,pfscan_VWF_A 0 no_errors 0 0 0 51 0 0 50 7 12.28 213 0 0.00 293 102 25.82 NPHP3-AS1 0 genome.wustl.edu 37 3 132440645 132440645 + RNA SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 132440645 132440645 A G SNP NPHP3-AS1 ENST00000489343 human ensembl 74_37 1 known rna NULL NULL 0.174 0 0 0 no_errors 0 0 0 107 0 0 91 33 26.61 120 1 0.83 177 50 22.03 STAG1 0 genome.wustl.edu 37 3 136221539 136221539 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 136221539 136221539 G A SNP STAG1 ENST00000383202 human ensembl 74_37 -1 known silent c.759 p.A253 0.169 pfam_STAG,superfamily_ARM-type_fold pfam_STAG,superfamily_ARM-type_fold 0 no_errors rs113504457 G->A 0 86 0 0 60 18 23.08 242 0 0.00 290 91 23.76 NME9 0 genome.wustl.edu 37 3 138023764 138023764 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 138023764 138023764 C T SNP NME9 ENST00000333911 human ensembl 74_37 -1 known missense c.742 p.V248I 0.033 pfam_Nucleoside_diP_kinase,superfamily_Nucleoside_diP_kinase,smart_Nucleoside_diP_kinase pfam_Nucleoside_diP_kinase,pfam_Thioredoxin_domain,superfamily_Nucleoside_diP_kinase,superfamily_Thioredoxin-like_fold,smart_Nucleoside_diP_kinase,prints_Nucleoside_diP_kinase 0 no_errors 0 0 0 16 0 0 16 6 27.27 89 0 0.00 129 38 22.75 ESYT3 0 genome.wustl.edu 37 3 138183253 138183253 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 138183253 138183253 C T SNP ESYT3 ENST00000389567 human ensembl 74_37 1 known nonsense c.982 p.R328* 0.016 pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,prints_C2_dom,pfscan_C2_dom pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,prints_C2_dom,pfscan_C2_dom 0 no_errors 0 0 0 33 0 0 34 3 8.11 87 0 0.00 98 43 30.50 CLSTN2 0 genome.wustl.edu 37 3 140123400 140123400 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 140123400 140123400 G T SNP CLSTN2 ENST00000458420 human ensembl 74_37 1 known missense c.429 p.K143N 1 superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin pfam_Cadherin,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin 0 no_errors 0 0 0 72 0 0 51 18 26.09 217 0 0.00 260 82 23.84 ACPL2 0 genome.wustl.edu 37 3 141011863 141011863 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 141011863 141011863 G A SNP ACPL2 ENST00000286353 human ensembl 74_37 1 known missense c.1259 p.R420Q 0.992 pfam_His_Pase_superF_clade-2 pfam_His_Pase_superF_clade-2 0 no_errors rs150898568 G->A 0 27 0 0 21 7 25 235 0 0.00 287 77 21.15 ATR 0 genome.wustl.edu 37 3 142269028 142269028 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 142269028 142269028 C T SNP ATR ENST00000350721 human ensembl 74_37 -1 known silent c.2922 p.T974 0.998 superfamily_ARM-type_fold pfam_PI3/4_kinase_cat_dom,pfam_PIK-rel_kinase_FAT,pfam_UME,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_UME,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_HEAT_type_2,pfscan_PI3/4_kinase_cat_dom 0 no_errors 0 0 0 53 0 0 62 15 19.48 165 0 0.00 232 87 27.27 CHST2 0 genome.wustl.edu 37 3 142840518 142840518 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 142840518 142840518 G A SNP CHST2 ENST00000309575 human ensembl 74_37 1 known missense c.860 p.R287H 1 pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase,pirsf_Carbohydrate_sulfotransferase pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase,pirsf_Carbohydrate_sulfotransferase 0 no_errors 0 0 0 35 0 0 25 6 19.35 66 0 0.00 77 23 23.00 FAM194A 0 genome.wustl.edu 37 3 150377915 150377915 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 150377915 150377915 G A SNP FAM194A ENST00000295910 human ensembl 74_37 -1 known missense c.1756 p.L586F 0 NULL NULL 0 no_errors 0 0 0 51 0 0 33 7 17.5 177 0 0.00 242 56 18.79 AADACL2 0 genome.wustl.edu 37 3 151461924 151461924 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 151461924 151461924 G A SNP AADACL2 ENST00000356517 human ensembl 74_37 1 known silent c.405 p.T135 0.046 pfam_AB_hydrolase_3,pfam_CarbesteraseB,pfam_Steryl_acetyl_hydrolase,pirsf_Arylacetamide_deacetylase pfam_AB_hydrolase_3,pfam_CarbesteraseB,pfam_Steryl_acetyl_hydrolase,pirsf_Arylacetamide_deacetylase 0 no_errors rs539885775 G->A 0 84 0 0 72 27 27.27 248 1 0.40 297 122 29.05 ARHGEF26 0 genome.wustl.edu 37 3 153839950 153839950 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 153839950 153839950 G T SNP ARHGEF26 ENST00000356448 human ensembl 74_37 1 known missense c.169 p.G57W 0.001 NULL pfam_DH-domain,pfam_SH3_domain,pfam_SH3_2,pfam_Pleckstrin_homology,superfamily_DH-domain,superfamily_SH3_domain,smart_DH-domain,smart_Pleckstrin_homology,smart_SH3_domain,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_DH-domain 0 no_errors 0 0 0 85 0 0 95 24 20.17 132 1 0.75 151 48 24.12 KCNAB1 0 genome.wustl.edu 37 3 155838426 155838426 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 155838426 155838426 C T SNP KCNAB1 ENST00000490337 human ensembl 74_37 1 known missense c.26 p.A9V 0.008 NULL pfam_NADP_OxRdtase_dom,superfamily_NADP_OxRdtase_dom,prints_K_chnl_volt-dep_bsu_KCNAB-rel,prints_K_chnl_volt-dep_bsu_KCNAB1,prints_K_chnl_volt-dep_bsu_KCNAB3,tigrfam_K_chnl_volt-dep_bsu_KCNAB 0 no_errors rs370498904 C->T 0 63 0 0 36 16 30.77 180 1 0.55 229 66 22.37 SLITRK3 0 genome.wustl.edu 37 3 164907221 164907221 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 164907221 164907221 G A SNP SLITRK3 ENST00000241274 human ensembl 74_37 -1 known silent c.1398 p.N466 0.128 smart_Leu-rich_rpt_typical-subtyp pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C 0 no_errors rs140074591 G->A 0.9998,0.0001997 55 0 0 55 25 31.25 209 0 0.00 178 62 25.83 EGFEM1P 0 genome.wustl.edu 37 3 168539010 168539010 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 168539010 168539010 T C SNP EGFEM1P ENST00000382864 human ensembl 74_37 1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 47 0 0 29 16 35.56 160 0 0.00 182 68 27.20 LRRC34 0 genome.wustl.edu 37 3 169514051 169514051 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 169514051 169514051 C T SNP LRRC34 ENST00000446859 human ensembl 74_37 -1 known missense c.1015 p.A339T 0.792 smart_Leu-rich_rpt_RNase_inh_sub-typ pfam_Leu-rich_rpt,smart_Leu-rich_rpt_RNase_inh_sub-typ 0 no_errors 0 0 0 34 0 0 41 13 24.07 247 0 0.00 255 90 26.09 USP13 0 genome.wustl.edu 37 3 179470125 179470125 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 179470125 179470125 T A SNP USP13 ENST00000263966 human ensembl 74_37 1 known missense c.1762 p.F588I 1 pfam_Peptidase_C19/C67,pirsf_Ubiquitinyl_hydrolase,pfscan_Peptidase_C19/C67 pfam_Peptidase_C19/C67,pfam_UBA/Ts_N,pfam_Znf_UBP,superfamily_UBA-like,smart_Znf_UBP,smart_UBA/transl_elong_EF1B_N_euk,pirsf_Ubiquitinyl_hydrolase,pfscan_UBA/transl_elong_EF1B_N_euk,pfscan_Znf_UBP,pfscan_Peptidase_C19/C67 0 no_errors 0 0 0 117 0 0 107 20 15.75 244 0 0.00 365 90 19.78 KLHL6 0 genome.wustl.edu 37 3 183209837 183209837 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 183209837 183209837 C T SNP KLHL6 ENST00000341319 human ensembl 74_37 -1 known missense c.1744 p.E582K 0.994 pfam_Kelch_1,smart_Kelch_1,pirsf_Kelch-like_gigaxonin pfam_Kelch_1,pfam_BACK,pfam_BTB_POZ,pfam_Kelch_2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like 0 no_errors 0 0 0 60 0 0 51 19 27.14 95 0 0.00 118 34 22.22 KLHL24 0 genome.wustl.edu 37 3 183388867 183388867 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 183388867 183388867 G A SNP KLHL24 ENST00000242810 human ensembl 74_37 1 known missense c.1270 p.V424I 1 pfam_Kelch_1,pfam_Kelch_2,smart_Kelch_1,pirsf_Kelch-like_gigaxonin pfam_Kelch_1,pfam_BACK,pfam_BTB_POZ,pfam_Kelch_2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like 0 no_errors rs141080869 G->A 0 73 0 0 75 21 21.88 195 0 0.00 277 64 18.71 CAMK2N2 0 genome.wustl.edu 37 3 183979057 183979057 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 183979057 183979057 G A SNP CAMK2N2 ENST00000296238 human ensembl 74_37 -1 known missense c.17 p.P6L 1 NULL NULL 0 no_errors 0 0 0 15 0 0 14 14 48.28 55 0 0.00 61 15 19.74 EPHB3 0 genome.wustl.edu 37 3 184295133 184295133 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 184295133 184295133 C A SNP EPHB3 ENST00000330394 human ensembl 74_37 1 known missense c.1357 p.P453T 1 pirsf_Tyr_kinase_ephrin_rcpt,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 30 0 0 31 8 20.51 91 1 1.09 73 20 21.51 MAP3K13 0 genome.wustl.edu 37 3 185190885 185190885 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 185190885 185190885 G A SNP MAP3K13 ENST00000265026 human ensembl 74_37 1 known missense c.1766 p.R589H 1 pirsf_MAP3K12_MAP3K13,superfamily_Kinase-like_dom pirsf_MAP3K12_MAP3K13,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 82 0 0 75 12 13.79 199 0 0.00 239 73 23.32 LEPREL1 0 genome.wustl.edu 37 3 189681863 189681863 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 189681863 189681863 G A SNP LEPREL1 ENST00000319332 human ensembl 74_37 -1 known missense c.1918 p.R640C 0.989 pfam_Oxoglu/Fe-dep_dioxygenase,smart_Pro_4_hyd_alph pfam_Oxoglu/Fe-dep_dioxygenase,smart_Pro_4_hyd_alph 0 no_errors 0 0 0 38 0 0 41 11 21.15 137 0 0.00 239 54 18.43 ATP5I 0 genome.wustl.edu 37 4 668094 668094 + RNA SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 668094 668094 A G SNP ATP5I ENST00000505852 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 42 0 0 16 3 15.79 28 0 0.00 26 6 18.75 MYL5 0 genome.wustl.edu 37 4 673725 673725 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 673725 673725 C T SNP MYL5 ENST00000400159 human ensembl 74_37 1 known silent c.210 p.D70 0.011 NULL pfam_EF_hand_dom,smart_EF_hand_dom,pfscan_EF_hand_dom 0 no_errors 0 0 0 49 0 0 22 3 12 82 0 0.00 90 28 23.73 TMEM175 0 genome.wustl.edu 37 4 947094 947094 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 947094 947094 G T SNP TMEM175 ENST00000264771 human ensembl 74_37 1 known silent c.579 p.P193 0 NULL pfam_DUF1211_TMEM175 0 no_errors 0 0 0 14 0 0 6 5 45.45 76 0 0.00 80 19 19.19 FGFR3 0 genome.wustl.edu 37 4 1807583 1807583 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 1807583 1807583 G A SNP FGFR3 ENST00000340107 human ensembl 74_37 1 known silent c.1758 p.P586 0.999 pirsf_FGF_rcpt_fam,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom pirsf_FGF_rcpt_fam,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom 0 no_errors rs139020690 G->A 0 67 0 0 39 11 22 79 0 0.00 101 38 27.34 ENSG00000206113 0 genome.wustl.edu 37 4 2438654 2438654 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 2438654 2438654 C T SNP ENSG00000206113 ENST00000511731 human ensembl 74_37 1 known rna NULL NULL 0.004 0 0 0 no_errors 0 0 0 82 0 0 50 18 26.47 149 0 0.00 105 41 28.08 RGS12 0 genome.wustl.edu 37 4 3319272 3319272 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 3319272 3319272 G A SNP RGS12 ENST00000344733 human ensembl 74_37 1 known missense c.1375 p.G459S 0.017 NULL pfam_Raf-like_ras-bd,pfam_RGS_dom,pfam_PDZ,pfam_GoLoco_motif,superfamily_Regulat_G_prot_signal_superfam,superfamily_PDZ,smart_PDZ,smart_PTB/PI_dom,smart_Regulat_G_prot_signal_superfam,smart_Raf-like_ras-bd,smart_GoLoco_motif,pfscan_GoLoco_motif,pfscan_PDZ,pfscan_PTB/PI_dom,pfscan_Raf-like_ras-bd,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom 0 no_errors 0 0 0 44 0 0 18 13 41.94 99 0 0.00 103 52 33.33 SH3TC1 0 genome.wustl.edu 37 4 8229977 8229977 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 8229977 8229977 G A SNP SH3TC1 ENST00000245105 human ensembl 74_37 1 known silent c.2556 p.R852 0 NULL superfamily_SH3_domain,smart_SH3_domain,smart_TPR_repeat,pfscan_SH3_domain 0 no_errors 0 0 0 16 0 0 7 2 22.22 100 0 0.00 70 21 23.08 WDR1 0 genome.wustl.edu 37 4 10089931 10089931 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 10089931 10089931 C T SNP WDR1 ENST00000382452 human ensembl 74_37 -1 known missense c.703 p.G235S 1 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep 0 no_errors 0 0 0 52 1 1.89 29 13 30.95 208 1 0.48 194 59 23.32 ZNF518B 0 genome.wustl.edu 37 4 10446515 10446515 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 10446515 10446515 C T SNP ZNF518B ENST00000326756 human ensembl 74_37 -1 known missense c.1438 p.A480T 0 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 58 0 0 41 13 24.07 335 1 0.30 244 78 24.07 SLC34A2 0 genome.wustl.edu 37 4 25674846 25674846 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 25674846 25674846 G A SNP SLC34A2 ENST00000382051 human ensembl 74_37 1 known missense c.1186 p.A396T 0.997 pfam_Na/Pi_transpt,superfamily_ABC1_TM_dom,tigrfam_Na/Pi_transpt pfam_Na/Pi_transpt,superfamily_ABC1_TM_dom,tigrfam_Na/Pi_transpt 0 no_errors rs560657112 G->A 0.9998,0.0001997 19 0 0 15 5 25 49 0 0.00 45 19 29.69 PDS5A 0 genome.wustl.edu 37 4 39875961 39875961 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 39875961 39875961 C T SNP PDS5A ENST00000303538 human ensembl 74_37 -1 known missense c.2225 p.C742Y 1 superfamily_ARM-type_fold superfamily_ARM-type_fold 0 no_errors 0 0 0 168 0 0 90 28 23.73 282 0 0.00 234 95 28.79 SLC10A4 0 genome.wustl.edu 37 4 48485994 48485994 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 48485994 48485994 C T SNP SLC10A4 ENST00000273861 human ensembl 74_37 1 known missense c.416 p.A139V 1 pfam_BilAc/Na_symport pfam_BilAc/Na_symport 0 no_errors 0 0 0 25 0 0 16 6 27.27 12 0 0.00 11 6 35.29 TACR3 0 genome.wustl.edu 37 4 104510988 104510988 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 104510988 104510988 C T SNP TACR3 ENST00000304883 human ensembl 74_37 -1 known missense c.1249 p.D417N 0.322 NULL pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_NK3_rcpt,prints_Neurokn_rcpt,prints_GPCR_Rhodpsn,prints_NPY_rcpt,prints_NK1_rcpt 0 no_errors 0 0 0 50 0 0 30 21 41.18 166 0 0.00 177 75 29.76 UGT8 0 genome.wustl.edu 37 4 115544174 115544174 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 115544174 115544174 C T SNP UGT8 ENST00000310836 human ensembl 74_37 1 known silent c.138 p.H46 0.547 pfam_UDP_glucos_trans pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C 0 no_errors 0 0 0 58 0 0 40 4 9.09 108 0 0.00 140 10 6.67 SPATA5 0 genome.wustl.edu 37 4 123949431 123949431 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 123949431 123949431 A G SNP SPATA5 ENST00000274008 human ensembl 74_37 1 known missense c.1960 p.I654V 0.068 superfamily_P-loop_NTPase pfam_ATPase_AAA_core,pfam_DNA_helicase_Holl-junc_RuvB_N,superfamily_P-loop_NTPase,superfamily_Asp_de-COase-like_dom,smart_AAA+_ATPase 0 no_errors 0 0 0 97 0 0 50 8 13.79 215 0 0.00 218 75 25.34 UCP1 0 genome.wustl.edu 37 4 141484596 141484596 + Silent SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 141484596 141484596 T C SNP UCP1 ENST00000262999 human ensembl 74_37 -1 known silent c.402 p.T134 0.949 pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_uncoupling 0 no_errors 0 0 0 80 0 0 40 21 34.43 186 0 0.00 153 69 30.94 USP38 0 genome.wustl.edu 37 4 144106796 144106796 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 144106796 144106796 C T SNP USP38 ENST00000307017 human ensembl 74_37 1 known silent c.193 p.L65 1 NULL pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67 0 no_errors 0 0 0 9 0 0 16 7 30.43 101 0 0.00 130 46 26.14 ENSG00000221362 0 genome.wustl.edu 37 4 161925046 161925046 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 161925046 161925046 C T SNP ENSG00000221362 ENST00000408435 human ensembl 74_37 -1 novel rna NULL NULL 0.055 0 0 0 no_errors 0 0 0 56 0 0 49 23 31.94 85 0 0.00 61 32 34.04 TKTL2 0 genome.wustl.edu 37 4 164393092 164393092 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 164393092 164393092 G A SNP TKTL2 ENST00000280605 human ensembl 74_37 -1 known missense c.1795 p.R599C 0.806 pfam_Transketolase_C,superfamily_Transketo_C/Pyr-ferredox_oxred pfam_Transketolase_N,pfam_Transketolase-like_Pyr-bd,pfam_Transketolase_C,pfam_DH_E1,superfamily_Transketo_C/Pyr-ferredox_oxred,smart_Transketolase-like_Pyr-bd 0 no_errors 0 0 0 50 0 0 25 7 21.21 227 0 0.00 158 83 34.30 TKTL2 0 genome.wustl.edu 37 4 164393772 164393772 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 164393772 164393772 T C SNP TKTL2 ENST00000280605 human ensembl 74_37 -1 known missense c.1115 p.N372S 1 pfam_Transketolase-like_Pyr-bd,smart_Transketolase-like_Pyr-bd pfam_Transketolase_N,pfam_Transketolase-like_Pyr-bd,pfam_Transketolase_C,pfam_DH_E1,superfamily_Transketo_C/Pyr-ferredox_oxred,smart_Transketolase-like_Pyr-bd 0 no_errors 0 0 0 59 0 0 33 10 23.26 181 0 0.00 164 70 29.91 TLR3 0 genome.wustl.edu 37 4 187000162 187000162 + Silent SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 187000162 187000162 T C SNP TLR3 ENST00000296795 human ensembl 74_37 1 known silent c.610 p.L204 0.887 smart_Leu-rich_rpt_typical-subtyp pfam_TIR_dom,pfam_Leu-rich_rpt,superfamily_TIR_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_TIR_dom,pfscan_TIR_dom 0 no_errors 0 0 0 131 0 0 74 32 30.19 279 0 0.00 274 92 25.14 TLR3 0 genome.wustl.edu 37 4 187005965 187005965 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 187005965 187005965 C T SNP TLR3 ENST00000296795 human ensembl 74_37 1 known missense c.2653 p.R885W 0.999 pfam_TIR_dom,superfamily_TIR_dom,smart_TIR_dom pfam_TIR_dom,pfam_Leu-rich_rpt,superfamily_TIR_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_TIR_dom,pfscan_TIR_dom 0 no_errors 0 0 0 158 0 0 97 43 30.71 205 0 0.00 195 100 33.90 TPPP 0 genome.wustl.edu 37 5 665302 665302 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 665302 665302 C T SNP TPPP ENST00000360578 human ensembl 74_37 -1 known missense c.575 p.R192H 0.998 pfam_P25-alpha pfam_P25-alpha 0 no_errors 0 0 0 44 0 0 16 5 23.81 68 0 0.00 73 26 26.26 LPCAT1 0 genome.wustl.edu 37 5 1477535 1477535 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 1477535 1477535 G A SNP LPCAT1 ENST00000283415 human ensembl 74_37 -1 known missense c.883 p.R295W 0.998 NULL pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase,smart_EF_hand_dom,pfscan_EF_hand_dom 0 no_errors 0 0 0 47 0 0 20 4 16.67 135 0 0.00 87 33 27.50 SDHAP3 0 genome.wustl.edu 37 5 1593265 1593265 + RNA SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 1593265 1593265 C A SNP SDHAP3 ENST00000436493 human ensembl 74_37 -1 known rna NULL NULL 0.996 0 0 0 no_errors 0 0 0 92 0 0 59 24 28.92 81 0 0.00 78 47 37.60 CCT5 0 genome.wustl.edu 37 5 10260992 10260992 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 10260992 10260992 C T SNP CCT5 ENST00000280326 human ensembl 74_37 1 known missense c.962 p.A321V 1 pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,tigrfam_Chap_CCT_epsi pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,prints_Chaperone_TCP-1,prints_Chaprnin_Cpn60,tigrfam_Chap_CCT_epsi 0 no_errors 0 0 0 76 0 0 42 15 26.32 180 0 0.00 126 62 32.98 MYO10 0 genome.wustl.edu 37 5 16668465 16668465 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 16668465 16668465 A T SNP MYO10 ENST00000513610 human ensembl 74_37 -1 known missense c.5996 p.I1999N 1 pfscan_FERM_domain pfam_Myosin_head_motor_dom,pfam_MyTH4_dom,pfam_Pleckstrin_homology,pfam_FERM_central,pfam_IQ_motif_EF-hand-BS,pfam_Ras-assoc,superfamily_P-loop_NTPase,superfamily_FERM_central,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,smart_Pleckstrin_homology,smart_MyTH4_dom,smart_Band_41_domain,pfscan_FERM_domain,pfscan_IQ_motif_EF-hand-BS,pfscan_MyTH4_dom,pfscan_Pleckstrin_homology,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 48 0 0 21 7 25 154 0 0.00 106 49 31.61 NIPBL 0 genome.wustl.edu 37 5 36985729 36985729 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 36985729 36985729 G A SNP NIPBL ENST00000282516 human ensembl 74_37 1 known missense c.2447 p.R816H 1 NULL superfamily_ARM-type_fold 0 no_errors rs80358359 G->A 0.9996,0.0003994 29 0 0 22 14 37.84 193 0 0.00 149 57 27.67 EGFLAM 0 genome.wustl.edu 37 5 38352386 38352386 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 38352386 38352386 G A SNP EGFLAM ENST00000354891 human ensembl 74_37 1 known silent c.498 p.A166 0.994 pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pfam_Laminin_G,pfam_Fibronectin_type3,pfam_EG-like_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_EG-like_dom,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom,pfscan_Fibronectin_type3,pfscan_Laminin_G 0 no_errors 0 0 0 45 0 0 28 5 15.15 141 0 0.00 177 10 5.35 HTR1A 0 genome.wustl.edu 37 5 63257266 63257266 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 63257266 63257266 G A SNP HTR1A ENST00000323865 human ensembl 74_37 -1 known missense c.281 p.A94V 1 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_NPY_rcpt pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_5HT1A_rcpt,prints_GPCR_Rhodpsn,prints_5HT_rcpt,prints_NPY_rcpt 0 no_errors 0 0 0 36 0 0 10 8 44.44 65 0 0.00 63 28 30.77 WDR41 0 genome.wustl.edu 37 5 76745632 76745632 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 76745632 76745632 C T SNP WDR41 ENST00000296679 human ensembl 74_37 -1 known missense c.650 p.R217H 1 superfamily_WD40_repeat_dom,smart_WD40_repeat pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep 0 no_errors 0 0 0 100 0 0 53 18 25.35 234 0 0.00 215 67 23.76 MSH3 0 genome.wustl.edu 37 5 80150076 80150076 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 80150076 80150076 A G SNP MSH3 ENST00000265081 human ensembl 74_37 1 known missense c.2941 p.T981A 1 pfam_DNA_mismatch_repair_MutS_C,superfamily_P-loop_NTPase,smart_DNA_mismatch_repair_MutS_C pfam_DNA_mismatch_repair_MutS_C,pfam_DNA_mismatch_repair_MutS_core,pfam_DNA_mmatch_repair_MutS_con_dom,pfam_DNA_mismatch_repair_MutS-lik_N,pfam_DNA_mismatch_repair_MutS_clamp,superfamily_DNA_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_DNA_mismatch_repair_MutS_N,superfamily_DNA_mmatch_repair_MutS_con_dom,smart_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_C 0 no_errors 0 0 0 41 0 0 28 17 37.78 203 0 0.00 161 45 21.84 GPR98 0 genome.wustl.edu 37 5 89949478 89949478 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 89949478 89949478 C T SNP GPR98 ENST00000405460 human ensembl 74_37 1 known missense c.4087 p.P1363S 1 superfamily_ConA-like_lec_gl_sf pfam_Calx_beta,pfam_EPTP,pfam_GPCR_2_secretin-like,pfam_GPS_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Gal_Oxase/kelch_b-propeller,smart_Calx_beta,pfscan_EAR,pfscan_GPS_dom,pfscan_GPCR_2-like 0 no_errors 0 0 0 29 0 0 25 11 29.73 287 1 0.35 336 133 28.36 GPR98 0 genome.wustl.edu 37 5 90050860 90050860 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 90050860 90050860 C T SNP GPR98 ENST00000405460 human ensembl 74_37 1 known missense c.11438 p.A3813V 0.974 NULL pfam_Calx_beta,pfam_EPTP,pfam_GPCR_2_secretin-like,pfam_GPS_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Gal_Oxase/kelch_b-propeller,smart_Calx_beta,pfscan_EAR,pfscan_GPS_dom,pfscan_GPCR_2-like 0 no_errors 0 0 0 55 0 0 26 18 40.91 263 1 0.38 226 110 32.64 KIAA0825 0 genome.wustl.edu 37 5 93820572 93820572 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 93820572 93820572 A G SNP KIAA0825 ENST00000427991 human ensembl 74_37 -1 known missense c.1034 p.L345S 0.983 NULL NULL 0 no_errors 0 0 0 112 1 0.88 78 30 27.78 273 0 0.00 236 76 24.36 ANKRD32 0 genome.wustl.edu 37 5 93990395 93990395 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 93990395 93990395 A G SNP ANKRD32 ENST00000265140 human ensembl 74_37 1 known missense c.1093 p.K365E 0 NULL pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_BRCT_dom,smart_BRCT_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom 0 no_errors 0 0 0 137 0 0 85 29 25.44 224 0 0.00 176 65 26.97 REEP5 0 genome.wustl.edu 37 5 112257874 112257874 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 112257874 112257874 A G SNP REEP5 ENST00000379638 human ensembl 74_37 -1 known missense c.14 p.M5T 1 NULL pfam_TB2_DP1_HVA22 0 no_errors 0 0 0 49 0 0 46 13 22.03 111 0 0.00 65 36 35.64 DMXL1 0 genome.wustl.edu 37 5 118506653 118506653 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 118506653 118506653 G A SNP DMXL1 ENST00000539542 human ensembl 74_37 1 known missense c.6167 p.R2056H 1 NULL pfam_Rav1p_C,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors rs373434175 G->A 0 101 0 0 48 22 31.43 250 0 0.00 222 83 27.21 TRPC7 0 genome.wustl.edu 37 5 135692352 135692352 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 135692352 135692352 C T SNP TRPC7 ENST00000513104 human ensembl 74_37 -1 known missense c.724 p.A242T 1 pfam_TRP_dom,tigrfam_TRP_channel pfam_Ion_trans_dom,pfam_TRP_dom,pfam_PKD1_2_channel,superfamily_Ankyrin_rpt-contain_dom,superfamily_ARM-type_fold,smart_Ankyrin_rpt,prints_TRPC7_channel,prints_TRPC_channel,tigrfam_TRP_channel 0 no_errors 0 0 0 20 0 0 10 6 37.5 159 0 0.00 108 37 25.52 HARS2 0 genome.wustl.edu 37 5 140075194 140075194 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 140075194 140075194 C T SNP HARS2 ENST00000230771 human ensembl 74_37 1 known silent c.501 p.G167 0.959 pfam_aa-tRNA-synt_IIb_cons-dom,pirsf_HisRS/HisZ,pfscan_aa-tRNA-synth_II,tigrfam_His-tRNA-ligase pfam_aa-tRNA-synt_IIb_cons-dom,pfam_Anticodon-bd,superfamily_Anticodon-bd,pirsf_HisRS/HisZ,pfscan_aa-tRNA-synth_II,tigrfam_His-tRNA-ligase 0 no_errors 0 0 0 105 0 0 59 21 26.25 237 0 0.00 191 73 27.44 PCDHA12 0 genome.wustl.edu 37 5 140256944 140256944 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 140256944 140256944 C T SNP PCDHA12 ENST00000398631 human ensembl 74_37 1 known silent c.1887 p.G629 0.986 pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin 0 no_errors 0 0 0 110 0 0 88 30 25.42 48 0 0.00 53 13 19.70 PCDHB6 0 genome.wustl.edu 37 5 140531055 140531055 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 140531055 140531055 C T SNP PCDHB6 ENST00000231136 human ensembl 74_37 1 known missense c.1217 p.A406V 0.024 pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin 0 no_errors 0 0 0 88 0 0 55 30 35.29 91 0 0.00 86 48 35.82 PCDHGA1 0 genome.wustl.edu 37 5 140712134 140712134 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 140712134 140712134 C T SNP PCDHGA1 ENST00000517417 human ensembl 74_37 1 known missense c.1883 p.T628M 0.999 pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin 0 no_errors 0 0 0 29 0 0 31 11 26.19 4 0 0.00 1 2 66.67 PCDHGA8 0 genome.wustl.edu 37 5 140774369 140774369 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 140774369 140774369 C T SNP PCDHGA8 ENST00000398604 human ensembl 74_37 1 known silent c.1989 p.A663 0.007 pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin 0 no_errors 0 0 0 49 0 0 35 13 26.53 52 0 0.00 43 11 20.37 ABLIM3 0 genome.wustl.edu 37 5 148627364 148627364 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 148627364 148627364 G A SNP ABLIM3 ENST00000309868 human ensembl 74_37 1 known missense c.1571 p.R524Q 1 NULL pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM 0 no_errors 0 0 0 44 1 2.22 21 7 25 248 0 0.00 166 48 22.43 ABLIM3 0 genome.wustl.edu 37 5 148627430 148627430 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 148627430 148627430 G A SNP ABLIM3 ENST00000309868 human ensembl 74_37 1 known missense c.1637 p.R546Q 1 NULL pfam_Znf_LIM,pfam_Villin_headpiece,superfamily_Villin_headpiece,smart_Znf_LIM,smart_Villin_headpiece,pfscan_Villin_headpiece,pfscan_Znf_LIM 0 no_errors rs138587496 G->A,C 0.9998,.,0.0001997 36 0 0 24 4 13.79 175 1 0.57 134 46 25.56 TCOF1 0 genome.wustl.edu 37 5 149756011 149756011 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 149756011 149756011 A G SNP TCOF1 ENST00000451292 human ensembl 74_37 1 known missense c.2168 p.Q723R 0.005 pfam_TCS_treacle pfam_TCS_treacle,smart_LisH_dimerisation,pfscan_LisH_dimerisation,prints_Treacle-like_TCS 0 no_errors 0 0 0 42 1 2.33 30 5 14.29 117 0 0.00 119 40 25.16 TENM2 0 genome.wustl.edu 37 5 167551991 167551991 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 167551991 167551991 G A SNP TENM2 ENST00000518659 human ensembl 74_37 1 known silent c.2145 p.T715 0.001 pfam_EGF_extracell,smart_EG-like_dom,pfscan_EG-like_dom pfam_Ten_N,pfam_EGF_extracell,superfamily_CarboxyPept-like_regulatory,superfamily_Quino_amine_DH_bsu,superfamily_ConA-like_lec_gl_sf,superfamily_Cytokine_IL1-like,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core 0 no_errors 0 0 0 30 0 0 25 6 19.35 87 0 0.00 47 24 33.80 DOCK2 0 genome.wustl.edu 37 5 169188602 169188602 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 169188602 169188602 G A SNP DOCK2 ENST00000256935 human ensembl 74_37 1 known missense c.2527 p.V843I 1 superfamily_ARM-type_fold pfam_DOCK_C,pfam_SH3_2,superfamily_SH3_domain,superfamily_Cyt_c-like_dom,superfamily_ARM-type_fold,superfamily_Ferritin-like_SF,smart_SH3_domain,pfscan_SH3_domain 0 no_errors 0 0 0 28 0 0 22 10 31.25 163 0 0.00 110 37 25.00 EIF4E1B 0 genome.wustl.edu 37 5 176073052 176073052 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 176073052 176073052 C T SNP EIF4E1B ENST00000512734 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 24 0 0 14 7 33.33 152 0 0.00 108 38 26.03 FLT4 0 genome.wustl.edu 37 5 180055995 180055995 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 180055995 180055995 A T SNP FLT4 ENST00000261937 human ensembl 74_37 -1 known missense c.990 p.N330K 1 NULL pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_VEGFR3_rcpt 0 no_errors 0 0 0 95 0 0 47 16 25.4 129 0 0.00 87 26 23.01 EXOC2 0 genome.wustl.edu 37 6 564069 564069 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 564069 564069 G A SNP EXOC2 ENST00000230449 human ensembl 74_37 -1 known missense c.1753 p.R585C 1 NULL pfam_IPT,superfamily_Ig_E-set,superfamily_Cullin_repeat-like_dom 0 no_errors 0 0 0 68 0 0 31 9 21.43 179 0 0.00 152 74 32.60 HIVEP1 0 genome.wustl.edu 37 6 12122183 12122183 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 12122183 12122183 C T SNP HIVEP1 ENST00000379388 human ensembl 74_37 1 known missense c.2155 p.P719S 0.109 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 42 0 0 22 8 26.67 161 0 0.00 146 62 29.81 ALDH5A1 0 genome.wustl.edu 37 6 24503567 24503567 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 24503567 24503567 G A SNP ALDH5A1 ENST00000348925 human ensembl 74_37 1 known missense c.515 p.R172H 1 pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,tigrfam_Succ_semiAld_DH pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,tigrfam_Succ_semiAld_DH 0 no_errors 0 0 0 19 0 0 12 3 20 201 0 0.00 151 60 28.44 OR11A1 0 genome.wustl.edu 37 6 29394998 29394998 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 29394998 29394998 G A SNP OR11A1 ENST00000377147 human ensembl 74_37 -1 known missense c.421 p.R141W 0 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,prints_Olfact_rcpt,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,prints_GPCR_Rhodpsn,prints_Olfact_rcpt,pfscan_GPCR_Rhodpsn_7TM 0 no_errors rs138146725 G->A 0 18 0 0 11 12 52.17 178 0 0.00 118 51 30.18 PPP1R10 0 genome.wustl.edu 37 6 30570148 30570148 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 30570148 30570148 C A SNP PPP1R10 ENST00000376511 human ensembl 74_37 -1 known missense c.2278 p.G760C 0.974 NULL pfam_TFIIS_N,pfam_Znf_CCCH,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,smart_Znf_CCCH 0 no_errors 0 0 0 79 0 0 38 21 35.59 75 0 0.00 62 40 39.22 PPP1R10 0 genome.wustl.edu 37 6 30572490 30572490 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 30572490 30572490 G A SNP PPP1R10 ENST00000376511 human ensembl 74_37 -1 known missense c.977 p.T326M 0.947 NULL pfam_TFIIS_N,pfam_Znf_CCCH,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,smart_Znf_CCCH 0 no_errors rs569378424 G->A 0.9998,0.0001997 49 0 0 25 8 24.24 271 0 0.00 227 101 30.79 SNORD84 0 genome.wustl.edu 37 6 31508922 31508922 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 31508922 31508922 G A SNP SNORD84 ENST00000584275 human ensembl 74_37 -1 known rna NULL NULL 0.902 0 0 0 no_errors 0 0 0 64 0 0 33 12 26.67 129 0 0.00 91 42 31.58 BAG6 0 genome.wustl.edu 37 6 31609347 31609347 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 31609347 31609347 G A SNP BAG6 ENST00000404765 human ensembl 74_37 -1 known missense c.2528 p.T843M 0.839 NULL pfam_DUF3538,pfam_Ubiquitin_dom,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup 0 no_errors 0 0 0 56 0 0 18 3 14.29 245 0 0.00 272 22 7.48 PPP1R2P1 0 genome.wustl.edu 37 6 32847176 32847176 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 32847176 32847176 C T SNP PPP1R2P1 ENST00000420261 human ensembl 74_37 -1 known rna NULL NULL 0.992 0 0 0 no_errors 0 0 0 163 0 0 68 36 34.62 134 0 0.00 105 52 33.12 ZBTB9 0 genome.wustl.edu 37 6 33424133 33424133 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 33424133 33424133 G A SNP ZBTB9 ENST00000395064 human ensembl 74_37 1 known missense c.1256 p.R419H 1 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 30 0 0 7 15 68.18 65 0 0.00 52 23 30.67 CPNE5 0 genome.wustl.edu 37 6 36711478 36711478 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 36711478 36711478 G A SNP CPNE5 ENST00000244751 human ensembl 74_37 -1 known silent c.1551 p.R517 0.791 smart_VWF_A,pfscan_VWF_A pfam_Copine,pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,smart_VWF_A,pfscan_C2_dom,pfscan_VWF_A 0 no_errors rs140027543 G->A 0.9998,0.0001997 47 0 0 36 15 29.41 80 0 0.00 59 18 23.38 DNAH8 0 genome.wustl.edu 37 6 38690926 38690926 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 38690926 38690926 G A SNP DNAH8 ENST00000449981 human ensembl 74_37 1 known missense c.341 p.R114Q 0.823 NULL pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase 0 no_errors 0 0 0 39 0 0 15 16 51.61 152 0 0.00 132 47 26.26 GLP1R 0 genome.wustl.edu 37 6 39033981 39033981 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 39033981 39033981 G A SNP GLP1R ENST00000373256 human ensembl 74_37 1 known silent c.411 p.P137 0.283 prints_GPCR_2_GLP1_rcpt pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_GLP1_rcpt,prints_GPCR_2_secretin-like,prints_GPCR_2_GLP1/glucagon_rcpt,prints_GPCR_2_GIP_rcpt 0 no_errors 0 0 0 30 0 0 19 7 26.92 120 0 0.00 92 54 36.99 PGC 0 genome.wustl.edu 37 6 41712478 41712478 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 41712478 41712478 A G SNP PGC ENST00000373025 human ensembl 74_37 -1 known missense c.128 p.L43P 0.017 pfam_Aspartic_peptidase_N,superfamily_Peptidase_aspartic_dom pfam_Aspartic_peptidase,pfam_Aspartic_peptidase_N,superfamily_Peptidase_aspartic_dom,prints_Aspartic_peptidase 0 no_errors 0 0 0 81 0 0 31 8 20.51 228 0 0.00 188 69 26.74 FRS3 0 genome.wustl.edu 37 6 41739096 41739096 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 41739096 41739096 G A SNP FRS3 ENST00000259748 human ensembl 74_37 -1 known missense c.740 p.T247I 0.195 NULL pfam_Insln_rcpt_S1,smart_Insln_rcpt_S1,pfscan_Insln_rcpt_S1 0 no_errors 0 0 0 54 0 0 35 15 30 194 1 0.51 113 54 32.14 PRICKLE4 0 genome.wustl.edu 37 6 41752671 41752671 + Splice_Site SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 41752671 41752671 A T SNP PRICKLE4 ENST00000335515 human ensembl 74_37 1 known splice_site c.241-2 e3-2 1 0 0 0 no_errors 0 0 0 42 0 0 21 6 22.22 95 0 0.00 66 36 35.29 POLH 0 genome.wustl.edu 37 6 43572406 43572406 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 43572406 43572406 G A SNP POLH ENST00000372236 human ensembl 74_37 1 known silent c.939 p.R313 1 pfam_DNA_pol_Y-fam_little_finger,pirsf_DNA_pol_eta pfam_DNA_repair_prot_UmuC-like,pfam_DNA_pol_Y-fam_little_finger,superfamily_DNA_pol_Y-fam_little_finger,pirsf_DNA_pol_eta,pfscan_DNA_repair_prot_UmuC-like_N 0 no_errors 0 0 0 92 0 0 64 24 27.27 310 0 0.00 235 99 29.55 SLC29A1 0 genome.wustl.edu 37 6 44197488 44197488 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 44197488 44197488 C A SNP SLC29A1 ENST00000313248 human ensembl 74_37 1 known missense c.511 p.L171M 0.935 superfamily_MFS_dom_general_subst_transpt,tigrfam_Eqnu_transpt pfam_Eqnu_transpt,superfamily_MFS_dom_general_subst_transpt,prints_Eqnu_transpt,tigrfam_Eqnu_transpt 0 no_errors 0 0 0 12 0 0 8 5 38.46 99 0 0.00 64 34 34.69 TDRD6 0 genome.wustl.edu 37 6 46656324 46656324 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 46656324 46656324 C T SNP TDRD6 ENST00000316081 human ensembl 74_37 1 known silent c.459 p.D153 0 NULL pfam_Tudor,smart_Tudor,pfscan_Tudor 0 no_errors 0 0 0 21 0 0 14 4 22.22 61 0 0.00 43 22 33.85 GPR115 0 genome.wustl.edu 37 6 47681763 47681763 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 47681763 47681763 G A SNP GPR115 ENST00000371220 human ensembl 74_37 1 known missense c.953 p.S318N 0 NULL pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like,prints_GPCR_2_Ig-hepta_rcpt 0 no_errors 0 0 0 61 0 0 21 6 22.22 164 0 0.00 137 47 25.41 PAQR8 0 genome.wustl.edu 37 6 52268691 52268691 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 52268691 52268691 C A SNP PAQR8 ENST00000360726 human ensembl 74_37 1 known missense c.680 p.P227H 1 pfam_HlyIII-related pfam_HlyIII-related,superfamily_C-type_lectin_fold 0 no_errors 0 0 0 18 0 0 8 7 46.67 160 1 0.62 147 47 24.23 ICK 0 genome.wustl.edu 37 6 52870048 52870048 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 52870048 52870048 T C SNP ICK ENST00000350082 human ensembl 74_37 -1 known missense c.1798 p.T600A 1 NULL pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 20 0 0 17 7 29.17 115 0 0.00 104 37 26.06 DST 0 genome.wustl.edu 37 6 56472620 56472620 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 56472620 56472620 T C SNP DST ENST00000370754 human ensembl 74_37 -1 known missense c.6707 p.K2236R 0 superfamily_ABC1_TM_dom pfam_Spectrin_repeat,pfam_Plectin_repeat,pfam_CH-domain,pfam_GAS2_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_GAS2_dom,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Plectin_repeat,smart_EF_hand_dom,smart_GAS2_dom,pfscan_CH-domain,pfscan_EF_hand_dom 0 no_errors 0 0 0 73 0 0 41 11 20.75 240 0 0.00 232 111 32.27 PHF3 0 genome.wustl.edu 37 6 64395254 64395254 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 64395254 64395254 C T SNP PHF3 ENST00000262043 human ensembl 74_37 1 known missense c.1631 p.P544L 1 NULL pfam_TFIIS_cen_dom,pfam_SPOC_C,pfam_Znf_PHD-finger,superfamily_TFIIS_cen_dom,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_TFS2M,pfscan_Znf_PHD-finger 0 no_errors 0 0 0 85 0 0 40 26 39.39 268 0 0.00 225 84 27.18 COL9A1 0 genome.wustl.edu 37 6 70961829 70961829 + Silent SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 70961829 70961829 C A SNP COL9A1 ENST00000357250 human ensembl 74_37 -1 known silent c.1866 p.G622 0.007 pfam_Collagen pfam_Collagen,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G 0 no_errors 0 0 0 55 0 0 38 12 24 164 0 0.00 144 55 27.64 EEF1A1 0 genome.wustl.edu 37 6 74227621 74227621 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 74227621 74227621 G A SNP EEF1A1 ENST00000309268 human ensembl 74_37 -1 known missense c.1301 p.A434V 1 pfam_Transl_elong_EFTu/EF1A_C,superfamily_Transl_elong_EF1A/Init_IF2_C,tigrfam_Transl_elong_EF1A_euk/arc pfam_EF_GTP-bd_dom,pfam_Transl_elong_EFTu/EF1A_C,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Transl_elong_EF1A/Init_IF2_C,superfamily_Transl_B-barrel,prints_EF_GTP-bd_dom,tigrfam_Transl_elong_EF1A_euk/arc 0 no_errors 0 0 0 77 0 0 49 16 24.24 91 0 0.00 71 46 38.98 PHIP 0 genome.wustl.edu 37 6 79770441 79770441 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 79770441 79770441 G T SNP PHIP ENST00000275034 human ensembl 74_37 -1 known missense c.284 p.P95H 1 NULL pfam_WD40_repeat,pfam_Bromodomain,superfamily_Quinonprotein_ADH-like_supfam,superfamily_Bromodomain,smart_WD40_repeat,smart_Bromodomain,pfscan_Bromodomain,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_Bromodomain 0 no_errors 0 0 0 86 0 0 37 15 28.85 315 0 0.00 250 112 30.94 GABRR1 0 genome.wustl.edu 37 6 89890146 89890146 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 89890146 89890146 G A SNP GABRR1 ENST00000454853 human ensembl 74_37 -1 known silent c.1011 p.R337 0.019 pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,tigrfam_Neur_channel pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_GABAAa_rho1_rcpt,prints_Neur_channel,prints_GABAAa_rho_rcpt,tigrfam_Neur_channel 0 no_errors rs185458142 G->A 0.9998,0.0001997 27 0 0 19 8 29.63 45 0 0.00 41 17 29.31 MDN1 0 genome.wustl.edu 37 6 90359895 90359895 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 90359895 90359895 G A SNP MDN1 ENST00000369393 human ensembl 74_37 -1 known nonsense c.16054 p.R5352* 0.999 pirsf_Midasin pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-3,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_AAA+_ATPase,smart_VWF_A,pirsf_Midasin,pfscan_VWF_A 0 no_errors 0 0 0 74 0 0 42 14 25 294 1 0.34 223 92 29.21 SIM1 0 genome.wustl.edu 37 6 100896539 100896539 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 100896539 100896539 C T SNP SIM1 ENST00000262901 human ensembl 74_37 -1 known missense c.559 p.G187S 1 superfamily_PAS pfam_SIM_C,pfam_PAS_fold_3,pfam_PAS_fold,pfam_bHLH_dom,superfamily_PAS,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,smart_PAC,pfscan_PAS,pfscan_bHLH_dom 0 no_errors 0 0 0 54 0 0 25 8 24.24 76 0 0.00 88 26 22.81 RNF146 0 genome.wustl.edu 37 6 127608197 127608197 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 127608197 127608197 G A SNP RNF146 ENST00000368314 human ensembl 74_37 1 known missense c.439 p.A147T 1 pfam_WWE-dom,smart_WWE-dom_subgr,pfscan_WWE-dom pfam_WWE-dom,smart_Znf_RING,smart_WWE-dom_subgr,pfscan_WWE-dom,pfscan_Znf_RING 0 no_errors 0 0 0 42 0 0 29 13 30.95 202 0 0.00 157 60 27.40 ENSG00000211996 0 genome.wustl.edu 37 6 130068906 130068906 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 130068906 130068906 C T SNP ENSG00000211996 ENST00000390707 human ensembl 74_37 1 novel rna NULL NULL 0 0 0 0 no_errors 0 0 0 27 0 0 10 7 41.18 45 0 0.00 54 15 21.74 L3MBTL3 0 genome.wustl.edu 37 6 130425719 130425719 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 130425719 130425719 A G SNP L3MBTL3 ENST00000361794 human ensembl 74_37 1 known missense c.1885 p.R629G 1 NULL pfam_Mbt,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_Mbt,smart_SAM,pfscan_Mbt,pfscan_SAM 0 no_errors 0 0 0 125 0 0 79 18 18.56 284 0 0.00 205 86 29.45 PDE7B 0 genome.wustl.edu 37 6 136475266 136475266 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 136475266 136475266 G A SNP PDE7B ENST00000308191 human ensembl 74_37 1 known missense c.532 p.A178T 1 pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom,prints_PDEase pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom,prints_PDEase 0 no_errors 0 0 0 48 0 0 28 11 28.21 165 1 0.60 127 55 30.22 MAP3K5 0 genome.wustl.edu 37 6 136934282 136934282 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 136934282 136934282 A G SNP MAP3K5 ENST00000359015 human ensembl 74_37 -1 known silent c.2391 p.N797 1 pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_SAM/pointed,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom 0 no_errors 0 0 0 118 0 0 77 25 24.51 243 1 0.41 255 95 27.07 HIVEP2 0 genome.wustl.edu 37 6 143092794 143092794 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 143092794 143092794 G A SNP HIVEP2 ENST00000012134 human ensembl 74_37 -1 known nonsense c.3082 p.R1028* 1 NULL pfam_Znf_C2H2,pfam_Znf_C2H2_jaz,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 16 0 0 19 12 38.71 114 0 0.00 71 27 27.55 NUP43 0 genome.wustl.edu 37 6 150063622 150063622 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 150063622 150063622 C A SNP NUP43 ENST00000340413 human ensembl 74_37 -1 known missense c.406 p.G136C 0.766 superfamily_WD40_repeat_dom,smart_WD40_repeat pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 66 0 0 27 13 32.5 226 0 0.00 195 64 24.71 PHF10 0 genome.wustl.edu 37 6 170117990 170117990 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 170117990 170117990 C T SNP PHF10 ENST00000339209 human ensembl 74_37 -1 known missense c.338 p.R113Q 1 NULL pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,pfscan_Znf_PHD-finger 0 no_errors 0 0 0 66 0 0 49 24 32.88 280 0 0.00 206 85 29.21 C7orf50 0 genome.wustl.edu 37 7 1166957 1166957 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 1166957 1166957 G A SNP C7orf50 ENST00000357429 human ensembl 74_37 -1 known missense c.65 p.A22V 0.005 NULL pfam_DUF2373 0 no_errors rs190705576 G->A 0 43 0 0 24 9 27.27 129 0 0.00 151 51 25.25 FOXK1 0 genome.wustl.edu 37 7 4799132 4799132 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 4799132 4799132 G A SNP FOXK1 ENST00000328914 human ensembl 74_37 1 known silent c.1602 p.S534 0.004 NULL pfam_TF_fork_head,pfam_FHA_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,smart_TF_fork_head,pfscan_FHA_dom,pfscan_TF_fork_head,prints_TF_fork_head 0 no_errors 0 0 0 39 1 2.5 22 8 26.67 54 0 0.00 68 21 23.60 RADIL 0 genome.wustl.edu 37 7 4856928 4856928 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 4856928 4856928 G A SNP RADIL ENST00000399583 human ensembl 74_37 -1 known missense c.1670 p.A557V 0.998 pfscan_Dilute pfam_Dil_domain,pfam_Ras-assoc,pfam_PDZ,superfamily_PDZ,superfamily_SMAD_FHA_domain,smart_Ras-assoc,smart_PDZ,pfscan_Dilute,pfscan_PDZ,pfscan_Ras-assoc 0 no_errors rs369367147 G->A 0 38 0 0 20 13 38.24 51 0 0.00 36 21 36.84 AIMP2 0 genome.wustl.edu 37 7 6062967 6062967 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 6062967 6062967 C T SNP AIMP2 ENST00000223029 human ensembl 74_37 1 known missense c.608 p.T203M 0.972 NULL superfamily_Glutathione-S-Trfase_C-like 0 no_errors 0 0 0 77 0 0 49 21 29.58 129 0 0.00 81 35 30.17 NOD1 0 genome.wustl.edu 37 7 30492633 30492633 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 30492633 30492633 G A SNP NOD1 ENST00000222823 human ensembl 74_37 -1 known nonsense c.400 p.R134* 0.99 NULL pfam_CARD,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_NACHT_NTPase,pfscan_CARD 0 no_errors rs371807148 G->A 0 20 0 0 4 8 66.67 37 0 0.00 29 12 29.27 ELMO1 0 genome.wustl.edu 37 7 36934507 36934507 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 36934507 36934507 C T SNP ELMO1 ENST00000310758 human ensembl 74_37 -1 known missense c.1553 p.R518H 1 NULL pfam_DUF3361,pfam_Engulfment_cell_motility_ELMO,superfamily_ARM-type_fold 0 no_errors 0 0 0 87 0 0 56 20 25.97 273 0 0.00 191 81 29.78 GLI3 0 genome.wustl.edu 37 7 42004804 42004804 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 42004804 42004804 G A SNP GLI3 ENST00000395925 human ensembl 74_37 -1 known silent c.3867 p.S1289 0.002 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 26 0 0 18 6 25 70 0 0.00 36 16 30.77 HECW1 0 genome.wustl.edu 37 7 43484345 43484345 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 43484345 43484345 G A SNP HECW1 ENST00000395891 human ensembl 74_37 1 known missense c.1574 p.R525Q 0.063 NULL pfam_HECT,pfam_WW_dom,pfam_C2_dom,superfamily_HECT,superfamily_WW_dom,superfamily_C2_dom,smart_C2_dom,smart_WW_dom,smart_HECT,pfscan_HECT,pfscan_C2_dom,pfscan_WW_dom 0 no_errors 0 0 0 34 0 0 17 3 15 54 0 0.00 53 17 24.29 FKBP6 0 genome.wustl.edu 37 7 72742644 72742644 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 72742644 72742644 G A SNP FKBP6 ENST00000252037 human ensembl 74_37 1 known missense c.124 p.V42I 0.958 NULL pfam_PPIase_FKBP_dom,smart_TPR_repeat,pfscan_TPR-contain_dom,pfscan_PPIase_FKBP_dom 0 no_errors 0 0 0 30 0 0 9 10 52.63 42 0 0.00 47 22 31.88 CLIP2 0 genome.wustl.edu 37 7 73787283 73787283 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 73787283 73787283 G A SNP CLIP2 ENST00000223398 human ensembl 74_37 1 known missense c.1402 p.A468T 1 NULL pfam_CAP-Gly_domain,superfamily_CAP-Gly_domain,superfamily_t-SNARE,pfscan_CAP-Gly_domain 0 no_errors 0 0 0 26 0 0 9 4 30.77 18 0 0.00 24 9 27.27 RHBDD2 0 genome.wustl.edu 37 7 75511247 75511247 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 75511247 75511247 C T SNP RHBDD2 ENST00000006777 human ensembl 74_37 1 known silent c.279 p.T93 0.999 pfam_Peptidase_S54_rhomboid_dom pfam_Peptidase_S54_rhomboid_dom 0 no_errors rs372131603 C->T 0 30 0 0 11 7 38.89 119 0 0.00 141 42 22.95 PCLO 0 genome.wustl.edu 37 7 82581891 82581891 + Missense_Mutation SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 82581891 82581891 T G SNP PCLO ENST00000333891 human ensembl 74_37 -1 known missense c.8378 p.E2793A 0.371 NULL pfam_Znf_piccolo,pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_PDZ,superfamily_Znf_FYVE_PHD,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ 0 no_errors 0 0 0 48 1 2.04 24 11 31.43 110 0 0.00 73 40 35.40 ABCB4 0 genome.wustl.edu 37 7 87053299 87053299 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 87053299 87053299 C T SNP ABCB4 ENST00000265723 human ensembl 74_37 -1 known missense c.2134 p.V712I 0.8 superfamily_ABC1_TM_dom,pfscan_ABC1_TM_dom pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,pfam_ABC_ATPase_put,pfam_Zeta_toxin_domain,superfamily_P-loop_NTPase,superfamily_ABC1_TM_dom,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom 0 no_errors 0 0 0 39 0 0 16 7 30.43 192 0 0.00 177 63 26.25 TRRAP 0 genome.wustl.edu 37 7 98509802 98509802 + Missense_Mutation SNP C C G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C G C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 98509802 98509802 C G SNP TRRAP ENST00000359863 human ensembl 74_37 1 known missense c.2165 p.S722C 1 superfamily_ARM-type_fold pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom 0 no_errors 0 0 0 50 0 0 35 16 31.37 243 0 0.00 167 64 27.71 KPNA7 0 genome.wustl.edu 37 7 98786033 98786033 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 98786033 98786033 C T SNP KPNA7 ENST00000327442 human ensembl 74_37 -1 known missense c.790 p.A264T 1 pfam_Armadillo,pfam_HEAT,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo pfam_Armadillo,pfam_HEAT,pfam_Importin-a_IBB,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo,pfscan_Importin-a_IBB 0 no_errors 0 0 0 21 0 0 9 3 25 94 0 0.00 93 29 23.58 ARPC1A 0 genome.wustl.edu 37 7 98951683 98951683 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 98951683 98951683 C T SNP ARPC1A ENST00000262942 human ensembl 74_37 1 known missense c.652 p.R218C 1 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pirsf_ARPC2/3_su1 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pirsf_ARPC2/3_su1,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 47 0 0 20 9 31.03 83 0 0.00 70 34 32.69 ZNF394 0 genome.wustl.edu 37 7 99091546 99091546 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 99091546 99091546 C T SNP ZNF394 ENST00000337673 human ensembl 74_37 -1 known missense c.1292 p.R431H 0.489 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN 0 no_errors 0 0 0 53 0 0 26 14 34.15 219 1 0.45 165 64 27.95 ZKSCAN1 0 genome.wustl.edu 37 7 99621354 99621354 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 99621354 99621354 T A SNP ZKSCAN1 ENST00000324306 human ensembl 74_37 1 known missense c.225 p.S75R 1 pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,pfscan_Tscrpt_reg_SCAN pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN 0 no_errors 0 0 0 39 0 0 18 8 30.77 170 0 0.00 139 42 23.20 SPDYE3 0 genome.wustl.edu 37 7 99905529 99905529 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 99905529 99905529 G T SNP SPDYE3 ENST00000332397 human ensembl 74_37 1 known missense c.21 p.Q7H 0.005 NULL pfam_Cell_cycle_regulatory_Spy1 0 no_errors 0 0 0 222 0 0 144 57 28.36 20 0 0.00 31 9 22.50 LRCH4 0 genome.wustl.edu 37 7 100176037 100176037 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 100176037 100176037 G A SNP LRCH4 ENST00000310300 human ensembl 74_37 -1 known missense c.833 p.P278L 0.901 NULL pfam_Leu-rich_rpt,pfam_CH-domain,superfamily_CH-domain,smart_Leu-rich_rpt_typical-subtyp,smart_CH-domain,pfscan_CH-domain 0 no_errors 0 0 0 70 0 0 39 15 27.78 134 0 0.00 84 41 32.80 PCOLCE 0 genome.wustl.edu 37 7 100205404 100205404 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 100205404 100205404 G A SNP PCOLCE ENST00000223061 human ensembl 74_37 1 known missense c.1157 p.C386Y 1 pfam_Netrin_module_non-TIMP,superfamily_TIMP-like_OB-fold,smart_Netrin_module_non-TIMP,pfscan_Netrin_domain pfam_CUB_dom,pfam_Netrin_module_non-TIMP,superfamily_CUB_dom,superfamily_TIMP-like_OB-fold,smart_CUB_dom,smart_Netrin_module_non-TIMP,pfscan_CUB_dom,pfscan_Netrin_domain 0 no_errors 0 0 0 63 0 0 19 10 34.48 200 0 0.00 169 66 28.09 GIGYF1 0 genome.wustl.edu 37 7 100282727 100282727 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 100282727 100282727 G A SNP GIGYF1 ENST00000275732 human ensembl 74_37 -1 known missense c.1235 p.S412F 1 NULL pfam_GYF,superfamily_GYF,smart_GYF,pfscan_GYF 0 no_errors 0 0 0 62 0 0 23 12 33.33 55 0 0.00 37 10 21.28 POLR2J 0 genome.wustl.edu 37 7 102116666 102116666 + Missense_Mutation SNP G G C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G C G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 102116666 102116666 G C SNP POLR2J ENST00000393794 human ensembl 74_37 -1 known missense c.105 p.I35M 1 pfam_RBP11-like_dimer,superfamily_RBP11-like_dimer pfam_RBP11-like_dimer,superfamily_RBP11-like_dimer 0 no_errors rs138574638 G->C 0 13 0 0 6 3 33.33 10 0 0.00 4 3 42.86 RELN 0 genome.wustl.edu 37 7 103155797 103155797 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 103155797 103155797 C T SNP RELN ENST00000424685 human ensembl 74_37 -1 known missense c.7954 p.D2652N 1 superfamily_Sialidases pfam_EGF_extracell,pfam_Reeler_dom,pfam_BNR_rpt,superfamily_Sialidases,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Reeler_dom 0 no_errors 0 0 0 37 0 0 10 8 44.44 124 0 0.00 82 40 32.52 KCND2 0 genome.wustl.edu 37 7 120373118 120373118 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 120373118 120373118 A G SNP KCND2 ENST00000331113 human ensembl 74_37 1 known missense c.1277 p.K426R 1 prints_K_chnl_volt-dep_Kv4 pfam_K_chnl_volt-dep_Kv4_C,pfam_T1-type_BTB,pfam_Ion_trans_dom,pfam_Shal-type,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv4,prints_K_chnl_volt-dep_Kv4.2,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv3 0 no_errors 0 0 0 38 0 0 34 10 22.73 208 0 0.00 176 57 24.46 CPED1 0 genome.wustl.edu 37 7 120740103 120740103 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 120740103 120740103 G A SNP CPED1 ENST00000310396 human ensembl 74_37 1 known silent c.873 p.T291 0.987 NULL NULL 0 no_errors 0 0 0 97 0 0 47 20 29.85 229 0 0.00 187 94 33.45 RNF133 0 genome.wustl.edu 37 7 122338557 122338557 + Missense_Mutation SNP A A C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A C A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 122338557 122338557 A C SNP RNF133 ENST00000340112 human ensembl 74_37 -1 known missense c.416 p.V139G 0.988 pfam_Protease-assoc_domain pfam_Protease-assoc_domain,pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING 0 no_errors 0 0 0 56 0 0 25 14 35.9 232 0 0.00 185 94 33.69 SND1 0 genome.wustl.edu 37 7 127727080 127727080 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 127727080 127727080 G A SNP SND1 ENST00000354725 human ensembl 74_37 1 known missense c.2395 p.A799T 1 superfamily_Staphylococal_nuclease_OB-fold,pirsf_Silence_cplx_Nase-comp_TudorSN pfam_Staphylococal_nuclease_OB-fold,pfam_Tudor,superfamily_Staphylococal_nuclease_OB-fold,smart_Staphylococal_nuclease_OB-fold,smart_Tudor,pirsf_Silence_cplx_Nase-comp_TudorSN,pfscan_Tudor,pfscan_Staphylococal_nuclease_OB-fold 0 no_errors 0 0 0 17 0 0 10 5 29.41 119 0 0.00 79 30 27.52 PODXL 0 genome.wustl.edu 37 7 131195725 131195725 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 131195725 131195725 G A SNP PODXL ENST00000541194 human ensembl 74_37 -1 known nonsense c.574 p.R192* 0 pirsf_Podocalyxin-like_p1 pfam_CD34/Podocalyxin,pirsf_Podocalyxin-like_p1 0 no_errors 0 0 0 66 0 0 30 18 37.5 152 0 0.00 135 57 29.69 PRSS1 0 genome.wustl.edu 37 7 142459791 142459791 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 142459791 142459791 G A SNP PRSS1 ENST00000311737 human ensembl 74_37 1 known missense c.367 p.V123M 0.698 pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1 pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A 0 no_errors rs144403091 G->A 0 45 0 0 20 19 48.72 149 0 0.00 99 45 31.25 ZNF783 0 genome.wustl.edu 37 7 148963535 148963535 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 148963535 148963535 C T SNP ZNF783 ENST00000434415 human ensembl 74_37 1 known missense c.134 p.T45M 0.974 pfam_DUF3669_Znf pfam_Znf_C2H2,pfam_Krueppel-associated_box,pfam_DUF3669_Znf,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel 0 no_errors rs570103600 C->T 0.9996,0.0003994 23 0 0 11 8 42.11 106 1 0.93 61 26 29.89 SSPO 0 genome.wustl.edu 37 7 149488498 149488498 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 149488498 149488498 G A SNP SSPO ENST00000262089 human ensembl 74_37 1 known rna NULL NULL 0.004 0 0 0 no_errors 0 0 0 36 0 0 20 10 32.26 58 0 0.00 52 25 32.47 NOS3 0 genome.wustl.edu 37 7 150698994 150698994 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 150698994 150698994 C T SNP NOS3 ENST00000297494 human ensembl 74_37 1 known missense c.1588 p.R530W 1 pfam_Flavodoxin/NO_synth,pirsf_NOS_euk,pfscan_Flavodoxin/NO_synth,prints_Flavdoxin pfam_NO_synthase_oxygenase_dom,pfam_FAD-binding_1,pfam_Flavodoxin/NO_synth,pfam_OxRdtase_FAD/NAD-bd,superfamily_NO_synthase_oxygenase_dom,superfamily_Riboflavin_synthase-like_b-brl,pirsf_NOS_euk,pfscan_Flavodoxin/NO_synth,prints_Flavoprot_Pyr_Nucl_cyt_Rdtase,prints_Flavdoxin 0 no_errors 0 0 0 34 0 0 17 10 37.04 92 0 0.00 55 20 26.67 HTR5A 0 genome.wustl.edu 37 7 154863229 154863229 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 154863229 154863229 G A SNP HTR5A ENST00000287907 human ensembl 74_37 1 known missense c.620 p.G207D 1 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_5HT_rcpt pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_5HT5A_rcpt,prints_5HT_rcpt 0 no_errors 0 0 0 34 0 0 16 8 32 102 0 0.00 94 36 27.48 VIPR2 0 genome.wustl.edu 37 7 158824739 158824739 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 158824739 158824739 G A SNP VIPR2 ENST00000262178 human ensembl 74_37 -1 known missense c.991 p.L331F 0.992 pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_VIP_rcpt_2,prints_GPCR_2_secretin-like,prints_GPCR_2_VIP_rcpt 0 no_errors 0 0 0 17 0 0 19 6 24 97 0 0.00 75 25 25.00 XKR6 0 genome.wustl.edu 37 8 10756220 10756220 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 10756220 10756220 C T SNP XKR6 ENST00000416569 human ensembl 74_37 -1 known missense c.1168 p.V390M 1 pfam_Transport_prot_XK pfam_Transport_prot_XK 0 no_errors rs377188885 C->T 0 29 0 0 17 12 41.38 125 0 0.00 101 52 33.99 CSGALNACT1 0 genome.wustl.edu 37 8 19277874 19277874 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 19277874 19277874 G A SNP CSGALNACT1 ENST00000311540 human ensembl 74_37 -1 known missense c.1109 p.T370M 0.97 pfam_Chond_GalNAc pfam_Chond_GalNAc 0 no_errors rs34492215 G->A 0.9996,0.0003994 55 0 0 37 14 27.45 122 0 0.00 123 32 20.65 PPP2R2A 0 genome.wustl.edu 37 8 26227708 26227708 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 26227708 26227708 C T SNP PPP2R2A ENST00000380737 human ensembl 74_37 1 known nonsense c.1123 p.R375* 1 superfamily_WD40_repeat_dom,pirsf_PP2A_PR55 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pirsf_PP2A_PR55,prints_PP2A_PR55 0 no_errors 0 0 0 58 0 0 54 13 19.4 263 0 0.00 219 89 28.90 PPP2R2A 0 genome.wustl.edu 37 8 26227751 26227751 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 26227751 26227751 G A SNP PPP2R2A ENST00000380737 human ensembl 74_37 1 known missense c.1166 p.R389H 0.999 superfamily_WD40_repeat_dom,pirsf_PP2A_PR55 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pirsf_PP2A_PR55,prints_PP2A_PR55 0 no_errors rs369862992 G->A 0 86 0 0 60 21 25.93 223 1 0.45 171 90 34.48 NRG1 0 genome.wustl.edu 37 8 32621338 32621338 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 32621338 32621338 G A SNP NRG1 ENST00000338921 human ensembl 74_37 1 known silent c.1365 p.S455 0.355 pfam_Neuregulin_1_C pfam_Neuregulin_1_C,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Ig-like_dom,prints_Neuregulin 0 no_errors 0 0 0 36 0 0 23 15 39.47 189 0 0.00 152 79 34.20 IDO2 0 genome.wustl.edu 37 8 39847306 39847306 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 39847306 39847306 C T SNP IDO2 ENST00000502986 human ensembl 74_37 1 known nonsense c.655 p.R219* 0.947 pfam_Indolamine_dOase pfam_Indolamine_dOase 0 no_errors rs199869245 C->T 0.9996,0.0003994 27 0 0 18 8 30.77 110 0 0.00 106 32 23.02 PRKDC 0 genome.wustl.edu 37 8 48805844 48805844 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 48805844 48805844 G A SNP PRKDC ENST00000314191 human ensembl 74_37 -1 known silent c.3702 p.G1234 0.997 NULL pfam_NUC194,pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom 0 no_errors 0 0 0 94 0 0 40 16 28.57 25 0 0.00 40 13 24.53 PRKDC 0 genome.wustl.edu 37 8 48811087 48811087 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 48811087 48811087 C T SNP PRKDC ENST00000314191 human ensembl 74_37 -1 known missense c.3407 p.R1136H 1 superfamily_ARM-type_fold pfam_NUC194,pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom 0 no_errors 0 0 0 50 0 0 28 11 28.21 201 0 0.00 169 66 28.09 C8orf46 0 genome.wustl.edu 37 8 67422332 67422332 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 67422332 67422332 G T SNP C8orf46 ENST00000305454 human ensembl 74_37 1 known silent c.282 p.V94 0.992 NULL NULL 0 no_errors 0 0 0 56 0 0 54 19 26.03 237 2 0.84 196 99 33.56 ZFHX4 0 genome.wustl.edu 37 8 77775727 77775727 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 77775727 77775727 C T SNP ZFHX4 ENST00000521891 human ensembl 74_37 1 known silent c.9777 p.G3259 0.998 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,superfamily_Adenylate_cyclase-assoc_CAP_N,smart_Znf_C2H2-like,smart_Znf_U1,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Znf_C2H2 0 no_errors 0 0 0 36 0 0 23 5 17.86 245 0 0.00 217 74 25.43 KCNS2 0 genome.wustl.edu 37 8 99440317 99440317 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 99440317 99440317 G A SNP KCNS2 ENST00000287042 human ensembl 74_37 1 known missense c.110 p.R37H 1 pfam_T1-type_BTB,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl_volt-dep_Kv9 pfam_T1-type_BTB,pfam_Ion_trans_dom,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv9,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv3,prints_K_chnl_volt-dep_Kv6,prints_K_chnl_volt-dep_Kv2 0 no_errors 0 0 0 36 0 0 17 9 34.62 25 0 0.00 22 6 21.43 FBXO43 0 genome.wustl.edu 37 8 101154178 101154178 + Missense_Mutation SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 101154178 101154178 T G SNP FBXO43 ENST00000428847 human ensembl 74_37 -1 known missense c.304 p.T102P 0 NULL pfam_Znf_C6HC,superfamily_F-box_dom,smart_Znf_C6HC 0 no_errors 0 0 0 53 0 0 38 15 28.3 151 0 0.00 143 65 31.10 SPAG1 0 genome.wustl.edu 37 8 101232550 101232550 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 101232550 101232550 C T SNP SPAG1 ENST00000251809 human ensembl 74_37 1 known missense c.1579 p.R527W 1 smart_TPR_repeat,pfscan_TPR-contain_dom pfam_TPR_1,pfam_TPR_2,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom 0 no_errors 0 0 0 99 0 0 52 28 35 271 1 0.36 228 103 31.12 UTP23 0 genome.wustl.edu 37 8 117782507 117782507 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 117782507 117782507 C T SNP UTP23 ENST00000309822 human ensembl 74_37 1 known nonsense c.265 p.R89* 1 pfam_Fcf1/Utp23 pfam_Fcf1/Utp23 0 no_errors 0 0 0 95 0 0 54 16 22.86 275 0 0.00 208 79 27.34 FAM83A 0 genome.wustl.edu 37 8 124219588 124219588 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 124219588 124219588 G A SNP FAM83A ENST00000318462 human ensembl 74_37 1 known missense c.965 p.S322N 0.952 NULL pfam_DUF1669 0 no_errors 0 0 0 18 0 0 7 4 36.36 44 0 0.00 30 6 16.67 ZFAT 0 genome.wustl.edu 37 8 135649862 135649862 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 135649862 135649862 G A SNP ZFAT ENST00000377838 human ensembl 74_37 -1 known missense c.290 p.P97L 0.023 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors rs375401473 G->A 0.9998,0.0001997 41 0 0 17 8 32 123 0 0.00 98 41 29.50 COL22A1 0 genome.wustl.edu 37 8 139601675 139601675 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 139601675 139601675 C T SNP COL22A1 ENST00000303045 human ensembl 74_37 -1 known missense c.4702 p.G1568R 1 pfam_Collagen pfam_Collagen,pfam_VWF_A,superfamily_ConA-like_lec_gl_sf,smart_VWF_A,smart_Laminin_G,pfscan_VWF_A 0 no_errors rs368533920 C->T 0 14 0 0 13 5 27.78 185 0 0.00 162 59 26.70 TSNARE1 0 genome.wustl.edu 37 8 143399961 143399961 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 143399961 143399961 C T SNP TSNARE1 ENST00000307180 human ensembl 74_37 -1 known missense c.928 p.A310T 0 superfamily_t-SNARE,smart_Syntaxin_N pfam_T_SNARE_dom,superfamily_t-SNARE,smart_Syntaxin_N,smart_T_SNARE_dom,pfscan_T_SNARE_dom 0 no_errors 0 0 0 22 0 0 13 6 31.58 44 0 0.00 35 13 27.08 JRK 0 genome.wustl.edu 37 8 143746582 143746582 + RNA SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 143746582 143746582 T A SNP JRK ENST00000422119 human ensembl 74_37 -1 known rna NULL NULL 0.84 0 0 0 no_errors 0 0 0 44 0 0 28 13 31.71 75 0 0.00 45 24 34.78 EEF1D 0 genome.wustl.edu 37 8 144671269 144671269 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 144671269 144671269 C T SNP EEF1D ENST00000423316 human ensembl 74_37 -1 known missense c.983 p.R328H 1 NULL pfam_Transl_elong_fac_EF1B_bsu/dsu,pfam_EF-1_beta_acid_region_euk,superfamily_Transl_elong_fac_EF1B_bsu/dsu,smart_Transl_elong_fac_EF1B_bsu/dsu 0 no_errors 0 0 0 29 0 0 21 12 36.36 39 0 0.00 37 18 32.73 BNC2 0 genome.wustl.edu 37 9 16436639 16436639 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 16436639 16436639 G A SNP BNC2 ENST00000380672 human ensembl 74_37 -1 known missense c.1553 p.A518V 1 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 82 0 0 41 19 31.67 199 2 1.00 191 76 28.46 DCAF12 0 genome.wustl.edu 37 9 34089566 34089566 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 34089566 34089566 G A SNP DCAF12 ENST00000361264 human ensembl 74_37 -1 known silent c.1047 p.Y349 0.536 superfamily_WD40_repeat_dom,smart_WD40_repeat pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 41 0 0 41 6 12.77 179 0 0.00 117 41 25.95 TLN1 0 genome.wustl.edu 37 9 35724310 35724310 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 35724310 35724310 C T SNP TLN1 ENST00000314888 human ensembl 74_37 -1 known missense c.533 p.R178Q 1 pfam_FERM_N,smart_Band_41_domain,pfscan_FERM_domain pfam_Talin_cent,pfam_Vinculin-bd_dom,pfam_ILWEQ_dom,pfam_FERM_N,pfam_FERM_central,pfam_Insln_rcpt_S1,superfamily_Talin_cent,superfamily_Vinculin/catenin,superfamily_FERM_central,smart_Band_41_domain,smart_ILWEQ_dom,pfscan_FERM_domain,pfscan_ILWEQ_dom 0 no_errors 0 0 0 38 0 0 17 4 19.05 130 0 0.00 96 51 34.69 ENSG00000250850 0 genome.wustl.edu 37 9 37002793 37002793 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 37002793 37002793 C T SNP ENSG00000250850 ENST00000509911 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 40 0 0 21 11 34.38 27 0 0.00 17 7 29.17 SPATA31D5P 0 genome.wustl.edu 37 9 84534435 84534435 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 84534435 84534435 C T SNP SPATA31D5P ENST00000527857 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 71 0 0 39 7 15.22 94 0 0.00 76 15 16.48 CTSL 0 genome.wustl.edu 37 9 90343563 90343563 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 90343563 90343563 A G SNP CTSL ENST00000340342 human ensembl 74_37 1 known missense c.460 p.K154E 1 pfam_Peptidase_C1A_C,smart_Peptidase_C1A_C pfam_Peptidase_C1A_C,pfam_Prot_inhib_I29,smart_Prot_inhib_I29,smart_Peptidase_C1A_C,prints_Peptidase_C1A_C 0 no_errors 0 0 0 75 0 0 32 14 30.43 149 0 0.00 85 46 34.33 SEMA4D 0 genome.wustl.edu 37 9 91994251 91994251 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 91994251 91994251 C T SNP SEMA4D ENST00000356444 human ensembl 74_37 -1 known missense c.1957 p.V653I 0 NULL pfam_Semap_dom,pfam_Plexin_repeat,pfam_Immunoglobulin,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_Ig_sub,smart_Ig_sub2,pfscan_Semap_dom,pfscan_Ig-like_dom 0 no_errors 0 0 0 33 1 2.94 25 10 28.57 224 0 0.00 172 76 30.65 ANKRD19P 0 genome.wustl.edu 37 9 95576206 95576206 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 95576206 95576206 C T SNP ANKRD19P ENST00000460854 human ensembl 74_37 1 known rna NULL NULL 0.27 0 0 0 no_errors 0 0 0 211 0 0 113 49 30.06 61 0 0.00 61 18 22.78 ENSG00000226668 0 genome.wustl.edu 37 9 95646205 95646205 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 95646205 95646205 G A SNP ENSG00000226668 ENST00000411450 human ensembl 74_37 1 known rna NULL NULL 0.005 0 0 0 no_errors 0 0 0 157 0 0 94 48 33.8 63 0 0.00 58 18 23.38 C9orf89 0 genome.wustl.edu 37 9 95870091 95870091 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 95870091 95870091 C T SNP C9orf89 ENST00000466409 human ensembl 74_37 1 known missense c.143 p.A48V 0.997 superfamily_DEATH-like_dom superfamily_DEATH-like_dom 0 no_errors 0 0 0 73 0 0 35 14 28 239 0 0.00 154 73 32.02 SLC35D2 0 genome.wustl.edu 37 9 99122450 99122450 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 99122450 99122450 G A SNP SLC35D2 ENST00000253270 human ensembl 74_37 -1 known silent c.333 p.S111 1 pfam_UAA pfam_Tpt_PEP_trans_dom,pfam_UAA 0 no_errors 0 0 0 53 0 0 26 10 27.78 261 0 0.00 220 67 23.26 GRIN3A 0 genome.wustl.edu 37 9 104385644 104385644 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 104385644 104385644 G A SNP GRIN3A ENST00000361820 human ensembl 74_37 -1 known missense c.2570 p.A857V 1 pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,smart_Iontro_glu_rcpt pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,superfamily_Peripla_BP_I,smart_Glu_rcpt_Glu/Gly-bd,smart_Iontro_glu_rcpt,prints_NMDA_rcpt 0 no_errors 0 0 0 104 0 0 60 23 27.71 164 0 0.00 141 59 29.35 ABCA1 0 genome.wustl.edu 37 9 107646762 107646762 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 107646762 107646762 C T SNP ABCA1 ENST00000374736 human ensembl 74_37 -1 known missense c.248 p.R83H 1 NULL pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like 0 no_errors 0 0 0 123 0 0 72 24 25 228 0 0.00 248 90 26.63 SLC46A2 0 genome.wustl.edu 37 9 115652022 115652022 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 115652022 115652022 C T SNP SLC46A2 ENST00000374228 human ensembl 74_37 -1 known missense c.940 p.G314S 0.977 pfam_MFS,superfamily_MFS_dom_general_subst_transpt pfam_MFS,superfamily_MFS_dom_general_subst_transpt,prints_Tet-R_TetA/multi-R_MdtG 0 no_errors 0 0 0 53 0 0 15 13 46.43 173 0 0.00 113 63 35.59 RGS3 0 genome.wustl.edu 37 9 116268675 116268675 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 116268675 116268675 G A SNP RGS3 ENST00000350696 human ensembl 74_37 1 known silent c.987 p.P329 0.01 pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ pfam_RGS_dom,pfam_C2_dom,pfam_PDZ,superfamily_Regulat_G_prot_signal_superfam,superfamily_C2_dom,superfamily_PDZ,smart_C2_dom,smart_PDZ,smart_Regulat_G_prot_signal_superfam,pfscan_C2_dom,pfscan_PDZ,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom 0 no_errors rs565492325 G->A 0.9998,0.0001997 29 0 0 16 6 27.27 140 0 0.00 96 49 33.79 ENG 0 genome.wustl.edu 37 9 130587557 130587557 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 130587557 130587557 G T SNP ENG ENST00000373203 human ensembl 74_37 -1 known missense c.769 p.P257T 0.005 NULL pfam_ZP_dom 0 no_errors 0 0 0 12 0 0 8 4 33.33 53 0 0.00 43 12 21.82 FAM73B 0 genome.wustl.edu 37 9 131804565 131804565 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 131804565 131804565 G A SNP FAM73B ENST00000477088 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 16 0 0 24 13 35.14 151 0 0.00 105 49 31.61 HMCN2 0 genome.wustl.edu 37 9 133267461 133267461 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 133267461 133267461 G A SNP HMCN2 ENST00000487727 human ensembl 74_37 1 known rna NULL NULL 0.883 0 0 0 no_errors 0 0 0 60 0 0 44 7 13.73 52 0 0.00 29 10 25.64 PRRC2B 0 genome.wustl.edu 37 9 134354747 134354747 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 134354747 134354747 C A SNP PRRC2B ENST00000357304 human ensembl 74_37 1 known missense c.4867 p.L1623M 1 NULL pfam_BAT2_N 0 no_errors 0 0 0 41 0 0 16 3 15.79 73 0 0.00 79 15 15.96 NTNG2 0 genome.wustl.edu 37 9 135102273 135102273 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 135102273 135102273 C T SNP NTNG2 ENST00000360670 human ensembl 74_37 1 known missense c.895 p.R299C 0.877 pfam_EGF_laminin,smart_EGF_laminin pfam_Laminin_N,pfam_EGF_laminin,pfam_EGF_extracell,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_EGF_laminin,pfscan_Laminin_N 0 no_errors 0 0 0 41 0 0 28 9 23.68 13 0 0.00 8 4 33.33 SURF6 0 genome.wustl.edu 37 9 136199551 136199551 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 136199551 136199551 G A SNP SURF6 ENST00000372022 human ensembl 74_37 -1 known missense c.439 p.R147W 0.172 pfam_Surf6 pfam_Surf6 0 no_errors 0 0 0 30 0 0 19 10 34.48 101 0 0.00 78 47 37.01 ADAMTS13 0 genome.wustl.edu 37 9 136291138 136291138 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 136291138 136291138 C T SNP ADAMTS13 ENST00000371929 human ensembl 74_37 1 known silent c.495 p.D165 0.239 pfam_Peptidase_M12B,pfscan_Peptidase_M12B pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,superfamily_Thrombospondin_1_rpt,superfamily_CUB_dom,smart_ADAM_Cys-rich,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS 0 no_errors 0 0 0 25 0 0 23 7 23.33 112 0 0.00 105 29 21.64 OLFM1 0 genome.wustl.edu 37 9 138011647 138011647 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 138011647 138011647 G A SNP OLFM1 ENST00000371793 human ensembl 74_37 1 known missense c.1081 p.E361K 1 pfam_Olfac-like,superfamily_Quinonprotein_ADH-like_supfam,smart_Olfac-like,pfscan_Olfac-like pfam_Olfac-like,pfam_Noelin-1,superfamily_Quinonprotein_ADH-like_supfam,smart_Olfac-like,pfscan_Olfac-like 0 no_errors 0 0 0 15 0 0 13 6 31.58 121 0 0.00 100 44 30.34 SNAPC4 0 genome.wustl.edu 37 9 139272182 139272182 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139272182 139272182 G A SNP SNAPC4 ENST00000298532 human ensembl 74_37 -1 known missense c.4097 p.A1366V 0.325 NULL pfam_SANT/Myb,superfamily_Homeodomain-like,smart_SANT/Myb,pfscan_Myb-like_dom 0 no_errors 0 0 0 13 0 0 8 3 27.27 55 0 0.00 34 10 22.73 SNAPC4 0 genome.wustl.edu 37 9 139289753 139289753 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139289753 139289753 G A SNP SNAPC4 ENST00000298532 human ensembl 74_37 -1 known silent c.468 p.G156 0.997 NULL pfam_SANT/Myb,superfamily_Homeodomain-like,smart_SANT/Myb,pfscan_Myb-like_dom 0 no_errors 0 0 0 28 0 0 19 8 29.63 180 0 0.00 119 43 26.54 MAMDC4 0 genome.wustl.edu 37 9 139751042 139751042 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139751042 139751042 T C SNP MAMDC4 ENST00000485732 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 25 0 0 14 9 39.13 41 0 0.00 44 16 26.67 LCN12 0 genome.wustl.edu 37 9 139848225 139848225 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139848225 139848225 G A SNP LCN12 ENST00000371633 human ensembl 74_37 1 known missense c.325 p.G109S 0 pfam_Lipocln_cytosolic_FA-bd_dom,superfamily_Calycin-like,prints_N_gelatinase pfam_Lipocln_cytosolic_FA-bd_dom,superfamily_Calycin-like,prints_PstgldnD_synth,prints_N_gelatinase 0 no_errors 0 0 0 43 0 0 31 8 20.51 62 0 0.00 47 11 18.97 ABCA2 0 genome.wustl.edu 37 9 139911670 139911670 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139911670 139911670 G A SNP ABCA2 ENST00000265662 human ensembl 74_37 -1 known missense c.2531 p.T844M 1 NULL pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like 0 no_errors 0 0 0 23 0 0 18 7 28 63 0 0.00 59 19 24.36 PFKP 0 genome.wustl.edu 37 10 3147406 3147406 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 3147406 3147406 T C SNP PFKP ENST00000460445 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 21 0 0 16 5 23.81 108 0 0.00 87 26 23.01 MYO3A 0 genome.wustl.edu 37 10 26500901 26500901 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 26500901 26500901 C T SNP MYO3A ENST00000543632 human ensembl 74_37 1 known nonsense c.1906 p.R636* 0 smart_Myosin_head_motor_dom pfam_Myosin_head_motor_dom,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_P-loop_NTPase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Myosin_head_motor_dom,pfscan_Prot_kinase_dom,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 24 0 0 15 4 21.05 60 0 0.00 40 22 35.48 ACBD5 0 genome.wustl.edu 37 10 27524095 27524095 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 27524095 27524095 G T SNP ACBD5 ENST00000375888 human ensembl 74_37 -1 known missense c.222 p.F74L 1 pfam_Acyl-CoA-binding_protein,superfamily_Acyl-CoA-binding_protein,pirsf_M-assoc_diazepam-bd-inh,prints_Acyl-CoA-binding_protein pfam_Acyl-CoA-binding_protein,superfamily_Acyl-CoA-binding_protein,pirsf_M-assoc_diazepam-bd-inh,prints_Acyl-CoA-binding_protein 0 no_errors 0 0 0 109 0 0 45 25 35.71 294 0 0.00 265 99 27.20 ZNF32-AS2 0 genome.wustl.edu 37 10 44141597 44141597 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 44141597 44141597 C T SNP ZNF32-AS2 ENST00000418966 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors rs199726414 C->T 0 33 0 0 15 5 25 242 0 0.00 162 83 33.88 RBP3 0 genome.wustl.edu 37 10 48389493 48389493 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 48389493 48389493 C T SNP RBP3 ENST00000224600 human ensembl 74_37 -1 known missense c.1385 p.R462H 0 pfam_Interphotoreceptor_retinol-bd,smart_Interphotoreceptor_retinol-bd pfam_Interphotoreceptor_retinol-bd,pfam_Interphotorcpt_retinol-bd_N,smart_Interphotoreceptor_retinol-bd 0 no_errors 0 0 0 43 1 2.27 27 11 28.95 147 0 0.00 124 33 21.02 FRMPD2 0 genome.wustl.edu 37 10 49440315 49440315 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 49440315 49440315 G T SNP FRMPD2 ENST00000374201 human ensembl 74_37 -1 known silent c.1011 p.S337 0.007 NULL pfam_PDZ,pfam_FERM_central,pfam_FERM_PH-like_C,pfam_FERM_N,superfamily_PDZ,superfamily_FERM_central,superfamily_Kinase-like_dom,smart_KIND,smart_Band_41_domain,smart_PDZ,pfscan_FERM_domain,pfscan_PDZ,prints_Band_41_fam 0 no_errors 0 0 0 36 0 0 23 5 17.86 254 2 0.78 207 74 26.33 WDFY4 0 genome.wustl.edu 37 10 50028336 50028336 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 50028336 50028336 G A SNP WDFY4 ENST00000325239 human ensembl 74_37 1 known missense c.5563 p.D1855N 0 NULL pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 43 0 0 28 8 22.22 61 0 0.00 37 13 26.00 C10orf71 0 genome.wustl.edu 37 10 50532273 50532273 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 50532273 50532273 C T SNP C10orf71 ENST00000374144 human ensembl 74_37 1 known silent c.1683 p.P561 0 NULL NULL 0 no_errors 0 0 0 20 0 0 22 4 15.38 176 0 0.00 118 56 32.18 OGDHL 0 genome.wustl.edu 37 10 50946024 50946024 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 50946024 50946024 C T SNP OGDHL ENST00000374103 human ensembl 74_37 -1 known missense c.2486 p.R829H 1 pfam_Transketolase-like_Pyr-bd,smart_Transketolase-like_Pyr-bd,pirsf_2oxoglutarate_DH_E1,tigrfam_2oxoglutarate_DH_E1 pfam_DH_E1,pfam_Transketolase-like_Pyr-bd,smart_Transketolase-like_Pyr-bd,pirsf_2oxoglutarate_DH_E1,tigrfam_2oxoglutarate_DH_E1 0 no_errors 0 0 0 56 0 0 48 13 21.31 74 0 0.00 48 18 27.27 ANK3 0 genome.wustl.edu 37 10 61840358 61840358 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 61840358 61840358 G A SNP ANK3 ENST00000280772 human ensembl 74_37 -1 known nonsense c.4369 p.R1457* 1 NULL pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt 0 no_errors 0 0 0 58 0 0 40 9 18.37 88 0 0.00 94 32 25.20 ANK3 0 genome.wustl.edu 37 10 61843307 61843307 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 61843307 61843307 C T SNP ANK3 ENST00000280772 human ensembl 74_37 -1 known silent c.4143 p.Q1381 1 NULL pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt 0 no_errors 0 0 0 153 0 0 90 40 30.77 397 0 0.00 273 152 35.68 DNA2 0 genome.wustl.edu 37 10 70182065 70182065 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 70182065 70182065 A T SNP DNA2 ENST00000399180 human ensembl 74_37 -1 known missense c.2872 p.F958I 0.118 superfamily_P-loop_NTPase pfam_DNA_replication_fac_Dna2_N,superfamily_P-loop_NTPase 0 no_errors 0 0 0 65 0 0 48 13 21.31 333 1 0.30 236 99 29.55 TET1 0 genome.wustl.edu 37 10 70404878 70404878 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 70404878 70404878 G A SNP TET1 ENST00000373644 human ensembl 74_37 1 known missense c.2392 p.A798T 0.001 NULL pfam_Znf_CXXC,pfscan_Znf_CXXC 0 no_errors 0 0 0 51 1 1.92 33 11 25 279 1 0.36 250 84 25.15 TET1 0 genome.wustl.edu 37 10 70406647 70406647 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 70406647 70406647 A G SNP TET1 ENST00000373644 human ensembl 74_37 1 known silent c.4161 p.T1387 0.026 NULL pfam_Znf_CXXC,pfscan_Znf_CXXC 0 no_errors 0 0 0 97 0 0 71 17 19.32 299 0 0.00 216 79 26.51 ZSWIM8-AS1 0 genome.wustl.edu 37 10 75556851 75556851 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 75556851 75556851 G A SNP ZSWIM8-AS1 ENST00000456638 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors rs138567501 G->A 0 37 0 0 23 11 32.35 177 0 0.00 134 65 32.66 NUTM2B 0 genome.wustl.edu 37 10 81463611 81463611 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 81463611 81463611 T A SNP NUTM2B ENST00000429828 human ensembl 74_37 1 known missense c.246 p.F82L 0 NULL NULL 0 no_errors 0 0 0 46 0 0 18 8 30.77 12 0 0.00 14 3 17.65 RGR 0 genome.wustl.edu 37 10 86017732 86017732 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 86017732 86017732 C T SNP RGR ENST00000359452 human ensembl 74_37 1 known silent c.726 p.D242 0.043 pfscan_GPCR_Rhodpsn_7TM,prints_RPE_GPCR pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_RPE_GPCR,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 33 0 0 21 16 43.24 128 0 0.00 107 53 33.12 TNKS2 0 genome.wustl.edu 37 10 93590871 93590871 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 93590871 93590871 C A SNP TNKS2 ENST00000371627 human ensembl 74_37 1 known missense c.1208 p.P403H 1 superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom pfam_Ankyrin_rpt,pfam_Poly(ADP-ribose)pol_cat_dom,pfam_SAM_2,pfam_SAM_type1,superfamily_Ankyrin_rpt-contain_dom,superfamily_SAM/pointed,smart_Ankyrin_rpt,smart_SAM,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_SAM,pfscan_Poly(ADP-ribose)pol_cat_dom,prints_Ankyrin_rpt 0 no_errors 0 0 0 57 0 0 43 11 20.37 223 0 0.00 213 74 25.61 EXOC6 0 genome.wustl.edu 37 10 94608366 94608366 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 94608366 94608366 A T SNP EXOC6 ENST00000260762 human ensembl 74_37 1 known missense c.76 p.T26S 1 pirsf_Sec15 pfam_Sec15,pirsf_Sec15 0 no_errors 0 0 0 41 0 0 17 15 46.88 96 0 0.00 45 39 45.88 CYP26A1 0 genome.wustl.edu 37 10 94833787 94833787 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 94833787 94833787 C T SNP CYP26A1 ENST00000224356 human ensembl 74_37 1 known silent c.96 p.C32 0.987 NULL pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450_E_grp-I,prints_Cyt_P450,prints_Cyt_P450_B 0 no_errors 0 0 0 93 0 0 61 25 29.07 71 0 0.00 51 16 23.88 SORBS1 0 genome.wustl.edu 37 10 97116729 97116729 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 97116729 97116729 C T SNP SORBS1 ENST00000607232 human ensembl 74_37 -1 known silent c.1563 p.S521 0.551 NULL pfam_SH3_domain,pfam_SH3_2,pfam_Sorb,superfamily_SH3_domain,smart_Sorb,smart_SH3_domain,pfscan_Sorb,pfscan_SH3_domain,prints_p67phox,prints_SH3_domain 0 no_errors 0 0 0 33 1 2.94 21 10 32.26 154 0 0.00 145 65 30.95 ABCC2 0 genome.wustl.edu 37 10 101604103 101604103 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 101604103 101604103 C T SNP ABCC2 ENST00000370449 human ensembl 74_37 1 known missense c.3868 p.P1290S 1 superfamily_P-loop_NTPase,tigrfam_Multidrug-R_assoc pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC1_TM_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom,tigrfam_Multidrug-R_assoc 0 no_errors 0 0 0 41 0 0 28 10 25.64 161 0 0.00 124 50 28.74 DNMBP 0 genome.wustl.edu 37 10 101636972 101636972 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 101636972 101636972 G A SNP DNMBP ENST00000342239 human ensembl 74_37 -1 known missense c.4742 p.A1581V 0.996 pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain,prints_Spectrin_alpha_SH3 pfam_BAR_dom,pfam_SH3_domain,pfam_SH3_2,pfam_DH-domain,superfamily_DH-domain,superfamily_SH3_domain,smart_SH3_domain,smart_DH-domain,smart_BAR_dom,pfscan_BAR_dom,pfscan_SH3_domain,pfscan_DH-domain,prints_p67phox,prints_Spectrin_alpha_SH3 0 no_errors 0 0 0 103 0 0 76 26 25.49 222 1 0.45 193 81 29.45 COL17A1 0 genome.wustl.edu 37 10 105803591 105803591 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 105803591 105803591 A G SNP COL17A1 ENST00000353479 human ensembl 74_37 -1 known missense c.2426 p.V809A 0.153 NULL pfam_Collagen 0 no_errors 0 0 0 38 0 0 33 11 25 178 0 0.00 151 60 28.44 CCDC172 0 genome.wustl.edu 37 10 118084848 118084848 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 118084848 118084848 T A SNP CCDC172 ENST00000333254 human ensembl 74_37 1 known missense c.113 p.I38N 0.959 NULL NULL 0 no_errors 0 0 0 106 0 0 67 31 31.63 195 0 0.00 168 83 32.94 TACC2 0 genome.wustl.edu 37 10 123842741 123842741 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 123842741 123842741 G A SNP TACC2 ENST00000334433 human ensembl 74_37 1 known silent c.726 p.G242 0 NULL pfam_TACC 0 no_errors 0 0 0 41 0 0 22 11 33.33 78 0 0.00 54 19 26.03 JAKMIP3 0 genome.wustl.edu 37 10 133981517 133981517 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 133981517 133981517 C T SNP JAKMIP3 ENST00000477275 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors rs142883148 C->T 0 13 0 0 10 8 44.44 161 0 0.00 110 44 28.39 TTC40 0 genome.wustl.edu 37 10 134659597 134659597 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 134659597 134659597 G A SNP TTC40 ENST00000263170 human ensembl 74_37 -1 known silent c.885 p.G295 0 NULL NULL 0 no_errors 0 0 0 65 0 0 26 23 46.94 45 0 0.00 34 15 30.61 TTC40 0 genome.wustl.edu 37 10 134680891 134680891 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 134680891 134680891 G A SNP TTC40 ENST00000368586 human ensembl 74_37 -1 putative silent c.4731 p.D1577 0 NULL NULL 0 no_errors 0 0 0 31 0 0 14 8 36.36 208 0 0.00 127 59 31.72 CARS 0 genome.wustl.edu 37 11 3039682 3039682 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 3039682 3039682 T C SNP CARS ENST00000380525 human ensembl 74_37 -1 known missense c.1585 p.S529G 0.442 pfam_Cys-tRNA/MSH_ligase,pfam_Methionyl/Leucyl_tRNA_Synth,tigrfam_Cys-tRNA-ligase pfam_Cys-tRNA/MSH_ligase,pfam_Methionyl/Leucyl_tRNA_Synth,superfamily_tRNAsynth_1a_anticodon-bd,superfamily_Glutathione-S-Trfase_C-like,prints_Cys-tRNA/MSH_ligase,tigrfam_Cys-tRNA-ligase 0 no_errors 0 0 0 32 0 0 25 7 21.88 102 0 0.00 77 24 23.53 OR52J3 0 genome.wustl.edu 37 11 5068663 5068663 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 5068663 5068663 G A SNP OR52J3 ENST00000380370 human ensembl 74_37 1 known missense c.908 p.R303Q 0 NULL pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 60 0 0 27 12 30.77 200 0 0.00 200 50 19.92 OR52A5 0 genome.wustl.edu 37 11 5153619 5153619 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 5153619 5153619 C T SNP OR52A5 ENST00000307388 human ensembl 74_37 -1 known missense c.254 p.G85D 0 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 59 0 0 42 11 20.75 182 0 0.00 161 73 31.20 OR51V1 0 genome.wustl.edu 37 11 5221246 5221246 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 5221246 5221246 G T SNP OR51V1 ENST00000321255 human ensembl 74_37 -1 known missense c.685 p.L229M 0 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 47 0 0 32 6 15.79 146 0 0.00 128 36 21.95 DNHD1 0 genome.wustl.edu 37 11 6578413 6578413 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 6578413 6578413 C T SNP DNHD1 ENST00000254579 human ensembl 74_37 1 known nonsense c.7888 p.R2630* 0.009 NULL pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom,superfamily_P-loop_NTPase,superfamily_t-SNARE 0 no_errors 0 0 0 27 1 3.57 16 5 23.81 132 1 0.75 104 39 27.27 ILK 0 genome.wustl.edu 37 11 6632072 6632072 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 6632072 6632072 C T SNP ILK ENST00000526318 human ensembl 74_37 1 known rna NULL NULL 0.999 0 0 0 no_errors rs541609708 C->T 0.9998,0.0001997 62 0 0 38 14 26.92 163 1 0.61 146 40 21.39 DCHS1 0 genome.wustl.edu 37 11 6654735 6654735 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 6654735 6654735 G T SNP DCHS1 ENST00000299441 human ensembl 74_37 -1 known missense c.2363 p.P788H 0.999 superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin 0 no_errors 0 0 0 32 0 0 18 8 30.77 138 0 0.00 115 32 21.77 CTR9 0 genome.wustl.edu 37 11 10789707 10789707 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 10789707 10789707 A G SNP CTR9 ENST00000361367 human ensembl 74_37 1 known missense c.1959 p.I653M 0.997 pfscan_TPR-contain_dom pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom 0 no_errors 0 0 0 53 0 0 27 10 27.03 250 0 0.00 223 109 32.83 OTOG 0 genome.wustl.edu 37 11 17594759 17594759 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 17594759 17594759 G A SNP OTOG ENST00000399391 human ensembl 74_37 1 known missense c.2251 p.A751T 1 pfam_Unchr_dom_Cys-rich,smart_Unchr_dom_Cys-rich pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_AbfB,pfam_TIL_dom,superfamily_AbfB,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_EG-like_dom 0 no_errors rs527271032 G->A 0.9998,0.0001997 25 1 3.85 12 11 47.83 27 0 0.00 14 7 33.33 KCNC1 0 genome.wustl.edu 37 11 17757798 17757798 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 17757798 17757798 C T SNP KCNC1 ENST00000265969 human ensembl 74_37 1 known silent c.249 p.C83 1 pfam_T1-type_BTB,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl_volt-dep_Kv3 pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv3,prints_K_chnl_volt-dep_Kv3.1,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv9 0 no_errors 0 0 0 81 0 0 42 17 28.81 10 0 0.00 17 9 34.62 MRGPRX3 0 genome.wustl.edu 37 11 18158926 18158926 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 18158926 18158926 C T SNP MRGPRX3 ENST00000396275 human ensembl 74_37 1 known silent c.177 p.N59 0.304 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 29 0 0 17 6 26.09 46 0 0.00 44 27 38.03 SLC1A2 0 genome.wustl.edu 37 11 35333816 35333816 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 35333816 35333816 T C SNP SLC1A2 ENST00000278379 human ensembl 74_37 -1 known missense c.490 p.S164G 1 pfam_Na-dicarboxylate_symporter pfam_Na-dicarboxylate_symporter,prints_Na-dicarboxylate_symporter 0 no_errors 0 0 0 52 0 0 32 7 17.95 162 0 0.00 141 68 32.38 OR8J3 0 genome.wustl.edu 37 11 55904926 55904926 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 55904926 55904926 T C SNP OR8J3 ENST00000301529 human ensembl 74_37 -1 known missense c.269 p.K90R 0.054 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 52 0 0 26 13 33.33 62 0 0.00 50 22 30.56 ENSG00000269089 0 genome.wustl.edu 37 11 61735984 61735984 + Nonsense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 61735984 61735984 G T SNP ENSG00000269089 ENST00000601917 human ensembl 74_37 1 known nonsense c.409 p.G137* 0.002 NULL NULL 0 no_errors 0 0 0 90 0 0 51 14 21.54 165 2 1.20 121 48 28.40 INTS5 0 genome.wustl.edu 37 11 62417152 62417152 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 62417152 62417152 G A SNP INTS5 ENST00000330574 human ensembl 74_37 -1 known missense c.400 p.R134W 1 NULL NULL 0 no_errors 0 0 0 24 0 0 15 4 21.05 150 0 0.00 112 40 26.32 NXF1 0 genome.wustl.edu 37 11 62563546 62563546 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 62563546 62563546 C T SNP NXF1 ENST00000294172 human ensembl 74_37 -1 known missense c.1453 p.A485T 1 pfam_NTF2,pfscan_Nuclear_transport_factor_2_euk pfam_Tap_RNA-bd,pfam_NTF2,pfam_TAP_C_dom,pfam_Leu-rich_rpt,superfamily_UBA-like,smart_TAP_C_dom,pfscan_Nuclear_transport_factor_2_euk 0 no_errors 0 0 0 51 0 0 29 9 23.68 144 0 0.00 122 46 27.22 RCOR2 0 genome.wustl.edu 37 11 63682649 63682649 + Splice_Site SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 63682649 63682649 C T SNP RCOR2 ENST00000301459 human ensembl 74_37 -1 known splice_site c.265+1 e3+1 1 0 0 0 no_errors 0 0 0 9 0 0 5 5 50 85 0 0.00 70 32 31.37 CDC42BPG 0 genome.wustl.edu 37 11 64601226 64601226 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 64601226 64601226 C T SNP CDC42BPG ENST00000342711 human ensembl 74_37 -1 known missense c.2549 p.R850H 1 NULL pfam_Prot_kinase_dom,pfam_Citron,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Myotonic_dystrophy_kinase_coil,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_Pkinase_C,pfam_Pleckstrin_homology,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Pleckstrin_homology,smart_Citron,pfscan_CRIB_dom,pfscan_Pleckstrin_homology,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 45 0 0 20 9 31.03 86 0 0.00 74 23 23.71 MALAT1 0 genome.wustl.edu 37 11 65269313 65269313 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 65269313 65269313 G A SNP MALAT1 ENST00000534336 human ensembl 74_37 1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 112 0 0 44 18 29.03 299 2 0.66 217 102 31.97 MUS81 0 genome.wustl.edu 37 11 65633355 65633355 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 65633355 65633355 C T SNP MUS81 ENST00000308110 human ensembl 74_37 1 known missense c.1579 p.R527C 0.867 NULL pfam_ERCC4_domain,superfamily_Restrct_endonuc-II-like,superfamily_DNA_pol_b-like_N,smart_ERCC4_domain 0 no_errors 0 0 0 59 0 0 23 9 28.12 126 0 0.00 85 28 24.78 RIN1 0 genome.wustl.edu 37 11 66103856 66103856 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 66103856 66103856 C T SNP RIN1 ENST00000311320 human ensembl 74_37 -1 known silent c.18 p.E6 0.664 NULL pfam_VPS9,pfam_Ras-assoc,smart_SH2,smart_VPS9_subgr,smart_Ras-assoc,pfscan_Ras-assoc,pfscan_SH2,pfscan_VPS9 0 no_errors 0 0 0 59 0 0 32 13 28.89 60 0 0.00 44 10 18.52 SUV420H1 0 genome.wustl.edu 37 11 67925890 67925890 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 67925890 67925890 C T SNP SUV420H1 ENST00000304363 human ensembl 74_37 -1 known silent c.1923 p.A641 0 NULL pfam_SET_dom,smart_SET_dom,pfscan_SET_dom 0 no_errors 0 0 0 15 0 0 11 5 31.25 263 0 0.00 172 70 28.93 MRGPRF 0 genome.wustl.edu 37 11 68773305 68773305 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 68773305 68773305 C T SNP MRGPRF ENST00000309099 human ensembl 74_37 -1 known missense c.473 p.R158H 0.99 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 34 0 0 31 10 24.39 47 0 0.00 24 15 38.46 FGF3 0 genome.wustl.edu 37 11 69625447 69625447 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 69625447 69625447 C T SNP FGF3 ENST00000334134 human ensembl 74_37 -1 known missense c.346 p.E116K 1 pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam,prints_Fibroblast_GF_fam,prints_IL-1_fam/FGF_fam pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam,prints_Fibroblast_GF_fam,prints_IL-1_fam/FGF_fam 0 no_errors rs79472069 C->T 0.9998,0.0001997 51 0 0 32 11 25.58 106 0 0.00 77 33 30.00 ANO1 0 genome.wustl.edu 37 11 70007369 70007369 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 70007369 70007369 C T SNP ANO1 ENST00000355303 human ensembl 74_37 1 known missense c.1681 p.R561W 1 pfam_Anoctamin pfam_Anoctamin 0 no_errors 0 0 0 27 0 0 18 8 30.77 131 0 0.00 113 42 27.10 P2RY2 0 genome.wustl.edu 37 11 72945997 72945997 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 72945997 72945997 C T SNP P2RY2 ENST00000311131 human ensembl 74_37 1 known missense c.793 p.R265C 1 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_P2Y2_rcpt,prints_GPCR_Rhodpsn,prints_P2Y4_rcpt 0 no_errors rs148618782 C->T 0 20 0 0 15 4 20 97 0 0.00 96 19 16.38 ARHGEF17 0 genome.wustl.edu 37 11 73021101 73021101 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 73021101 73021101 C T SNP ARHGEF17 ENST00000263674 human ensembl 74_37 1 known missense c.1418 p.T473M 0.987 NULL pfam_DH-domain,superfamily_DH-domain,superfamily_WD40_repeat_dom,superfamily_Vinculin/catenin,smart_DH-domain,pfscan_DH-domain 0 no_errors 0 0 0 102 0 0 64 31 32.63 163 0 0.00 133 54 28.88 NDUFC2 0 genome.wustl.edu 37 11 77790746 77790746 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 77790746 77790746 A G SNP NDUFC2 ENST00000281031 human ensembl 74_37 -1 known silent c.45 p.D15 0.778 pfam_NADH-UbQ_OxRdtase_b14.5b_su,pirsf_NADH-UbQ_OxRdtase_b14.5b_su pfam_NADH-UbQ_OxRdtase_b14.5b_su,pirsf_NADH-UbQ_OxRdtase_b14.5b_su 0 no_errors 0 0 0 9 0 0 4 4 50 36 0 0.00 45 15 25.00 TENM4 0 genome.wustl.edu 37 11 78380640 78380640 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 78380640 78380640 G A SNP TENM4 ENST00000278550 human ensembl 74_37 -1 known silent c.6750 p.D2250 0.965 NULL pfam_Ten_N,pfam_EGF_extracell,pfam_YD,superfamily_CarboxyPept-like_regulatory,smart_EG-like_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core 0 no_errors 0 0 0 27 0 0 21 6 22.22 77 0 0.00 71 19 21.11 TENM4 0 genome.wustl.edu 37 11 78383337 78383337 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 78383337 78383337 C T SNP TENM4 ENST00000278550 human ensembl 74_37 -1 known missense c.5534 p.R1845H 1 NULL pfam_Ten_N,pfam_EGF_extracell,pfam_YD,superfamily_CarboxyPept-like_regulatory,smart_EG-like_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core 0 no_errors 0 0 0 38 0 0 32 12 27.27 178 0 0.00 133 51 27.72 DLG2 0 genome.wustl.edu 37 11 83984195 83984195 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 83984195 83984195 G A SNP DLG2 ENST00000418306 human ensembl 74_37 -1 known missense c.104 p.P35L 1 superfamily_PDZ,pirsf_M-assoc_guanylate_kinase pfam_PDZ,pfam_GK/Ca_channel_bsu,pfam_PDZ_assoc,pfam_SH3_2,pfam_SH3_domain,superfamily_P-loop_NTPase,superfamily_SH3_domain,superfamily_PDZ,smart_PDZ,smart_SH3_domain,smart_GK/Ca_channel_bsu,pirsf_M-assoc_guanylate_kinase,pfscan_PDZ,pfscan_SH3_domain,pfscan_Guanylate_kin-like 0 no_errors 0 0 0 141 0 0 74 29 28.16 189 0 0.00 154 63 29.03 SYTL2 0 genome.wustl.edu 37 11 85437818 85437818 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 85437818 85437818 C A SNP SYTL2 ENST00000359152 human ensembl 74_37 -1 known missense c.1254 p.E418D 0.3 NULL pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom 0 no_errors 0 0 0 61 0 0 36 21 36.84 252 0 0.00 242 62 20.39 KIAA1731 0 genome.wustl.edu 37 11 93425161 93425161 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 93425161 93425161 G T SNP KIAA1731 ENST00000411936 human ensembl 74_37 1 known missense c.1498 p.A500S 1 NULL NULL 0 no_errors 0 0 0 88 0 0 52 19 26.76 108 0 0.00 118 29 19.73 GPR83 0 genome.wustl.edu 37 11 94134311 94134311 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 94134311 94134311 C T SNP GPR83 ENST00000243673 human ensembl 74_37 -1 known missense c.103 p.V35M 0 NULL pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_NPY_rcpt 0 no_errors 0 0 0 16 0 0 7 4 36.36 108 0 0.00 79 21 21.00 LOC643733 0 genome.wustl.edu 37 11 104788843 104788843 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 104788843 104788843 C T SNP LOC643733 ENST00000527425 human ensembl 74_37 -1 known rna NULL NULL 0.969 0 0 0 no_errors 0 0 0 85 0 0 36 9 20 257 0 0.00 284 86 23.24 CWF19L2 0 genome.wustl.edu 37 11 107328471 107328471 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 107328471 107328471 C A SNP CWF19L2 ENST00000282251 human ensembl 74_37 -1 known missense c.72 p.Q24H 0.016 NULL pfam_Cwf19-like_C_dom-1,pfam_Cwf19-like_C_dom-2,superfamily_HIT-like 0 no_errors 0 0 0 72 0 0 37 15 28.85 192 0 0.00 143 77 35.00 C11orf88 0 genome.wustl.edu 37 11 111386791 111386791 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 111386791 111386791 C A SNP C11orf88 ENST00000529167 human ensembl 74_37 1 known missense c.295 p.L99I 0.001 NULL NULL 0 no_errors 0 0 0 337 0 0 201 68 25.28 230 0 0.00 166 80 32.52 IL18 0 genome.wustl.edu 37 11 112019397 112019397 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 112019397 112019397 C T SNP IL18 ENST00000280357 human ensembl 74_37 -1 known missense c.289 p.A97T 0.241 pfam_IL-1,superfamily_Cytokine_IL1-like,pirsf_IL-18 pfam_IL-1,superfamily_Cytokine_IL1-like,pirsf_IL-18,prints_IL-18 0 no_errors 0 0 0 252 0 0 142 51 26.42 265 1 0.38 211 69 24.64 AMICA1 0 genome.wustl.edu 37 11 118076603 118076603 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 118076603 118076603 G A SNP AMICA1 ENST00000356289 human ensembl 74_37 -1 known silent c.528 p.R176 0 pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom 0 no_errors 0 0 0 55 0 0 37 14 27.45 225 0 0.00 152 66 30.14 HYOU1 0 genome.wustl.edu 37 11 118917366 118917366 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 118917366 118917366 C A SNP HYOU1 ENST00000404233 human ensembl 74_37 -1 known missense c.2744 p.R915L 1 NULL pfam_Hsp_70_fam,pfam_MreB_Mrl,prints_Hsp_70_fam 0 no_errors 0 0 0 40 0 0 29 12 29.27 208 0 0.00 179 69 27.82 POU2F3 0 genome.wustl.edu 37 11 120176431 120176431 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 120176431 120176431 A G SNP POU2F3 ENST00000260264 human ensembl 74_37 1 known missense c.712 p.N238D 1 pfam_POU_specific,superfamily_Lambda_DNA-bd_dom,smart_POU_specific,pfscan_POU_specific,prints_POU pfam_POU_specific,pfam_Homeobox_dom,superfamily_Lambda_DNA-bd_dom,superfamily_Homeodomain-like,smart_POU_specific,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_POU_specific,prints_POU,prints_TF_octamer 0 no_errors 0 0 0 39 0 0 21 7 25 101 0 0.00 88 26 22.81 C11orf63 0 genome.wustl.edu 37 11 122775018 122775018 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 122775018 122775018 C T SNP C11orf63 ENST00000227349 human ensembl 74_37 1 known missense c.730 p.R244C 0.044 NULL NULL 0 no_errors 0 0 0 32 0 0 20 9 31.03 231 0 0.00 222 86 27.92 OR10G8 0 genome.wustl.edu 37 11 123900750 123900750 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 123900750 123900750 A G SNP OR10G8 ENST00000431524 human ensembl 74_37 1 known missense c.421 p.T141A 0 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors rs200971859 A->G 0.9998,0.0001997 53 0 0 27 8 22.86 23 0 0.00 24 5 17.24 SIAE 0 genome.wustl.edu 37 11 124509731 124509731 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 124509731 124509731 G A SNP SIAE ENST00000263593 human ensembl 74_37 -1 known silent c.999 p.D333 0.004 NULL pfam_DUF303_acetylest 0 no_errors rs371229601 G->A 0 60 0 0 26 25 49.02 184 1 0.54 153 60 28.17 CHEK1 0 genome.wustl.edu 37 11 125497651 125497651 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 125497651 125497651 G T SNP CHEK1 ENST00000438015 human ensembl 74_37 1 known missense c.215 p.G72V 1 pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 90 0 0 40 24 37.5 249 0 0.00 198 68 25.56 FLI1 0 genome.wustl.edu 37 11 128628012 128628012 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 128628012 128628012 G T SNP FLI1 ENST00000527786 human ensembl 74_37 1 known missense c.21 p.E7D 1 NULL pfam_Ets_dom,pfam_Pointed_dom,superfamily_SAM/pointed,smart_Pointed_dom,smart_Ets_dom,pfscan_Ets_dom,prints_Ets_dom 0 no_errors 0 0 0 14 0 0 13 4 23.53 115 0 0.00 94 18 16.07 GLB1L2 0 genome.wustl.edu 37 11 134237185 134237185 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 134237185 134237185 C T SNP GLB1L2 ENST00000339772 human ensembl 74_37 1 known missense c.839 p.T280M 0.999 pfam_Glycoside_Hdrlase_35,superfamily_Glycoside_hydrolase_SF,prints_Glycoside_Hdrlase_35 pfam_Glycoside_Hdrlase_35,pfam_Glyco_hydro_42_N,superfamily_Glycoside_hydrolase_SF,superfamily_Galactose-bd-like,prints_Glycoside_Hdrlase_35 0 no_errors rs147686340 C->T 0 74 1 1.33 56 22 28.21 210 0 0.00 164 74 30.96 IQSEC3 0 genome.wustl.edu 37 12 266277 266277 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 266277 266277 A G SNP IQSEC3 ENST00000326261 human ensembl 74_37 1 known missense c.2240 p.E747G 1 pfam_Sec7_dom,superfamily_Sec7_dom,smart_Sec7_dom,pfscan_Sec7_dom pfam_Sec7_dom,superfamily_Sec7_dom,smart_Sec7_dom,pfscan_IQ_motif_EF-hand-BS,pfscan_Sec7_dom 0 no_errors 0 0 0 23 1 4 10 10 50 94 0 0.00 60 18 23.08 VWF 0 genome.wustl.edu 37 12 6132810 6132810 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 6132810 6132810 C T SNP VWF ENST00000261405 human ensembl 74_37 -1 known silent c.3366 p.T1122 0 pirsf_VWF,pfam_Unchr_dom_Cys-rich,smart_Unchr_dom_Cys-rich pirsf_VWF,pfam_VWF_type-D,pfam_VWF_A,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_VWF_A,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_A,pfscan_VWF_C 0 no_errors rs373172467 C->T 0 114 0 0 69 27 28.12 90 0 0.00 56 23 28.40 SCNN1A 0 genome.wustl.edu 37 12 6471270 6471270 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 6471270 6471270 C T SNP SCNN1A ENST00000358945 human ensembl 74_37 -1 known silent c.822 p.T274 0 pfam_Na+channel_ASC,tigrfam_EnaC pfam_Na+channel_ASC,prints_Na+channel_ASC,tigrfam_EnaC 0 no_errors rs372634287 C->T 0 43 0 0 16 14 46.67 89 0 0.00 66 32 32.65 CLSTN3 0 genome.wustl.edu 37 12 7309220 7309220 + RNA SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 7309220 7309220 T A SNP CLSTN3 ENST00000331148 human ensembl 74_37 1 known rna NULL NULL 0.006 0 0 0 no_errors 0 0 0 29 0 0 15 7 31.82 80 0 0.00 83 17 17.00 A2ML1 0 genome.wustl.edu 37 12 9009835 9009835 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 9009835 9009835 T C SNP A2ML1 ENST00000299698 human ensembl 74_37 1 known missense c.2924 p.M975T 1 pfam_MacrogloblnA2_thiol-ester-bond,superfamily_Terpenoid_cyclase/PrenylTrfase pfam_A2M_comp,pfam_Macroglobln_a2,pfam_A2M_N_2,pfam_A-macroglobulin_rcpt-bd,pfam_A2M_N,pfam_MacrogloblnA2_thiol-ester-bond,pfam_SV_autoAg,superfamily_Terpenoid_cyclase/PrenylTrfase,superfamily_A-macroglobulin_rcpt-bd 0 no_errors rs202179061 T->C 0.9998,0.0001997 50 0 0 33 8 19.51 103 0 0.00 78 34 30.36 GPRC5A 0 genome.wustl.edu 37 12 13062048 13062048 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 13062048 13062048 G A SNP GPRC5A ENST00000014914 human ensembl 74_37 1 known missense c.865 p.V289M 0.989 NULL pfam_GPCR_3_C 0 no_errors 0 0 0 59 0 0 55 5 8.33 265 0 0.00 283 18 5.98 ARID2 0 genome.wustl.edu 37 12 46243410 46243410 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 46243410 46243410 G A SNP ARID2 ENST00000334344 human ensembl 74_37 1 known missense c.1763 p.S588N 0.996 NULL pfam_ARID/BRIGHT_DNA-bd,pfam_DNA-bd_RFX,superfamily_ARID/BRIGHT_DNA-bd,superfamily_ARM-type_fold,smart_ARID/BRIGHT_DNA-bd,pfscan_ARID/BRIGHT_DNA-bd 0 no_errors 0 0 0 121 0 0 63 21 25 210 0 0.00 169 54 24.00 PFKM 0 genome.wustl.edu 37 12 48528050 48528050 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 48528050 48528050 G A SNP PFKM ENST00000312352 human ensembl 74_37 1 known missense c.629 p.R210H 1 pfam_Phosphofructokinase_dom,superfamily_Phosphofructokinase_dom,pirsf_6-phosphofructokinase_euk,prints_Phosphofructokinase,tigrfam_6-phosphofructokinase_euk pfam_Phosphofructokinase_dom,superfamily_Phosphofructokinase_dom,pirsf_6-phosphofructokinase_euk,prints_Phosphofructokinase,tigrfam_6-phosphofructokinase_euk 0 no_errors 0 0 0 63 1 1.56 27 7 20.59 225 0 0.00 183 86 31.97 RARG 0 genome.wustl.edu 37 12 53608001 53608001 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 53608001 53608001 G T SNP RARG ENST00000394426 human ensembl 74_37 -1 known missense c.655 p.R219S 1 superfamily_Nucl_hormone_rcpt_ligand-bd,prints_Retinoic_acid_rcpt pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Retinoic_acid_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_Nuc_orph_rcpt,prints_Retinoid-X_rcpt/HNF4 0 no_errors 0 0 0 16 0 0 10 3 23.08 97 0 0.00 56 19 25.33 AMHR2 0 genome.wustl.edu 37 12 53819610 53819610 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 53819610 53819610 G A SNP AMHR2 ENST00000257863 human ensembl 74_37 1 known silent c.759 p.Q253 0.475 pirsf_Anti-muellerian_hrmn_rcpt_II,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom pirsf_Anti-muellerian_hrmn_rcpt_II,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Activin_rcpt,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 37 0 0 17 11 39.29 112 0 0.00 113 47 29.38 PCBP2 0 genome.wustl.edu 37 12 53865444 53865444 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 53865444 53865444 G A SNP PCBP2 ENST00000603815 human ensembl 74_37 1 known missense c.914 p.R305H 1 pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1 pfam_KH_dom_type_1,pfam_KH_dom_type_2,smart_KH_dom,pfscan_KH_dom_type_1 0 no_errors 0 0 0 45 0 0 36 3 7.69 168 0 0.00 110 37 25.17 OR6C1 0 genome.wustl.edu 37 12 55715136 55715136 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 55715136 55715136 C T SNP OR6C1 ENST00000379668 human ensembl 74_37 1 known silent c.753 p.G251 0.027 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 75 0 0 41 16 28.07 216 2 0.92 200 86 30.07 OR6C76 0 genome.wustl.edu 37 12 55820800 55820800 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 55820800 55820800 A G SNP OR6C76 ENST00000328314 human ensembl 74_37 1 known missense c.763 p.M255V 0.997 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 61 0 0 35 8 18.6 151 0 0.00 164 63 27.75 INHBC 0 genome.wustl.edu 37 12 57828744 57828744 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 57828744 57828744 G A SNP INHBC ENST00000309668 human ensembl 74_37 1 known silent c.75 p.Q25 0.902 prints_Inhibin_betaC pfam_TGF-b_C,pfam_TGF-b_N,smart_TGF-b_C,prints_Inhibin_betaC 0 no_errors 0 0 0 25 0 0 16 7 30.43 75 0 0.00 87 21 19.44 GRIP1 0 genome.wustl.edu 37 12 66786159 66786159 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 66786159 66786159 G A SNP GRIP1 ENST00000359742 human ensembl 74_37 -1 known missense c.2393 p.T798M 0.986 NULL pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ 0 no_errors rs200363939 G->A 0.9998,0.0001997 29 0 0 36 7 16.28 139 0 0.00 123 28 18.54 DCN 0 genome.wustl.edu 37 12 91550887 91550887 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 91550887 91550887 C T SNP DCN ENST00000052754 human ensembl 74_37 -1 known missense c.617 p.R206H 1 pirsf_SLRP_I_decor/aspor/byglycan pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,pirsf_SLRP_I_decor/aspor/byglycan 0 no_errors 0 0 0 49 1 2 24 14 36.84 196 0 0.00 158 63 28.38 C12orf74 0 genome.wustl.edu 37 12 93100478 93100478 + Missense_Mutation SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 93100478 93100478 T G SNP C12orf74 ENST00000397833 human ensembl 74_37 1 known missense c.71 p.L24R 0 NULL NULL 0 no_errors 0 0 0 48 0 0 46 7 13.21 99 0 0.00 105 35 25.00 LTA4H 0 genome.wustl.edu 37 12 96394809 96394809 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 96394809 96394809 G A SNP LTA4H ENST00000228740 human ensembl 74_37 -1 known silent c.1794 p.P598 0.005 pfam_Peptidase_M1_C,superfamily_ARM-type_fold,tigrfam_Leukotriene_A4_hydrolase pfam_Peptidase_M1_N,pfam_Peptidase_M1_C,superfamily_ARM-type_fold,prints_Peptidase_M1_N,tigrfam_Leukotriene_A4_hydrolase 0 no_errors 0 0 0 108 0 0 65 17 20.73 200 0 0.00 173 93 34.96 PRDM4 0 genome.wustl.edu 37 12 108145770 108145770 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 108145770 108145770 C T SNP PRDM4 ENST00000228437 human ensembl 74_37 -1 known missense c.548 p.G183D 1 pirsf_Znf_PRDM4 pfam_Znf_C2H2,smart_Znf_C2H2-like,pirsf_Znf_PRDM4,pfscan_SET_dom,pfscan_Znf_C2H2 0 no_errors 0 0 0 67 0 0 46 18 28.12 236 0 0.00 186 77 29.28 TCHP 0 genome.wustl.edu 37 12 110353318 110353318 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 110353318 110353318 G A SNP TCHP ENST00000312777 human ensembl 74_37 1 known silent c.1431 p.A477 0 NULL NULL 0 no_errors rs368260508 G->A 0 61 0 0 27 9 25 40 0 0.00 32 20 38.46 CCDC63 0 genome.wustl.edu 37 12 111291293 111291293 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 111291293 111291293 C T SNP CCDC63 ENST00000308208 human ensembl 74_37 1 known missense c.94 p.R32W 0.008 NULL NULL 0 no_errors 0 0 0 69 0 0 38 28 42.42 137 0 0.00 116 46 28.40 NAA25 0 genome.wustl.edu 37 12 112479884 112479884 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 112479884 112479884 C T SNP NAA25 ENST00000261745 human ensembl 74_37 -1 known missense c.2399 p.R800Q 0.999 NULL pfam_N-acetylTrfase_B_cplx_non-cat,pfscan_TPR-contain_dom 0 no_errors 0 0 0 67 0 0 30 14 31.82 289 0 0.00 249 91 26.76 HECTD4 0 genome.wustl.edu 37 12 112750858 112750858 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 112750858 112750858 C T SNP HECTD4 ENST00000377560 human ensembl 74_37 -1 known silent c.447 p.A149 0.032 NULL pfam_HECT,superfamily_HECT,superfamily_ConA-like_lec_gl_sf,smart_HECT,pfscan_HECT 0 no_errors 0 0 0 40 0 0 21 8 27.59 146 0 0.00 129 43 25.00 WSB2 0 genome.wustl.edu 37 12 118480647 118480647 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 118480647 118480647 G A SNP WSB2 ENST00000315436 human ensembl 74_37 -1 known silent c.558 p.H186 0.952 superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat_dom pfam_WD40_repeat,pfam_SOCS_C,superfamily_WD40_repeat_dom,smart_WD40_repeat,smart_SOCS_C,pfscan_SOCS_C,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep 0 no_errors 0 0 0 59 0 0 39 27 40.91 260 1 0.38 205 84 28.97 RAB35 0 genome.wustl.edu 37 12 120536641 120536641 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 120536641 120536641 C T SNP RAB35 ENST00000229340 human ensembl 74_37 -1 known missense c.451 p.A151T 1 pfam_Small_GTPase,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,pfam_Gtr1_RagA,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom 0 no_errors 0 0 0 23 0 0 14 6 30 111 0 0.00 87 34 28.10 ORAI1 0 genome.wustl.edu 37 12 122079267 122079267 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 122079267 122079267 G A SNP ORAI1 ENST00000330079 human ensembl 74_37 1 known silent c.630 p.Q210 0.677 pfam_CRAC_channel pfam_CRAC_channel 0 no_errors 0 0 0 57 0 0 20 4 16.67 68 0 0.00 45 15 25.00 TCTN2 0 genome.wustl.edu 37 12 124189166 124189166 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 124189166 124189166 G A SNP TCTN2 ENST00000303372 human ensembl 74_37 1 known missense c.1700 p.R567H 0.994 NULL pfam_DUF1619 0 no_errors 0 0 0 49 0 0 34 11 24.44 54 0 0.00 65 19 22.62 DHX37 0 genome.wustl.edu 37 12 125465190 125465190 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 125465190 125465190 G A SNP DHX37 ENST00000308736 human ensembl 74_37 -1 known missense c.584 p.T195I 0 NULL pfam_DUF1605,pfam_Helicase-assoc_dom,pfam_Helicase_C,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_T2SS_protein-E,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Helicase-assoc_dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C 0 no_errors 0 0 0 66 0 0 36 16 30.77 35 0 0.00 27 15 35.71 TMEM132C 0 genome.wustl.edu 37 12 129178485 129178485 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 129178485 129178485 G A SNP TMEM132C ENST00000435159 human ensembl 74_37 1 known missense c.1561 p.V521M 1 NULL NULL 0 no_errors 0 0 0 54 0 0 26 14 35 140 2 1.41 123 51 29.31 EP400 0 genome.wustl.edu 37 12 132445390 132445390 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 132445390 132445390 C A SNP EP400 ENST00000333577 human ensembl 74_37 1 known missense c.226 p.L76M 0.994 NULL pfam_SNF2_N,pfam_Helicase/SANT-assoc_DNA-bd,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Homeodomain-like,smart_HAS_subgr,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Myb-like_dom,pfscan_Helicase/SANT-assoc_DNA-bd,pfscan_Helicase_ATP-bd,pfscan_Helicase_C 0 no_errors 0 0 0 99 0 0 51 22 30.14 77 0 0.00 47 24 33.80 DDX51 0 genome.wustl.edu 37 12 132624232 132624232 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 132624232 132624232 G A SNP DDX51 ENST00000397333 human ensembl 74_37 -1 known missense c.1922 p.P641L 0.213 NULL pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,pfam_Helicase/UvrB_dom,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C 0 no_errors rs201039066 G->A 0.9996,0.0003994 23 0 0 8 10 55.56 57 0 0.00 49 25 33.78 MPHOSPH8 0 genome.wustl.edu 37 13 20222608 20222608 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 20222608 20222608 G A SNP MPHOSPH8 ENST00000414242 human ensembl 74_37 1 known missense c.1265 p.R422K 0.529 NULL pfam_Ankyrin_rpt,pfam_Chromo_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Chromo_domain/shadow 0 no_errors 0 0 0 43 0 0 14 7 33.33 225 1 0.44 166 69 29.36 PARP4 0 genome.wustl.edu 37 13 25008754 25008754 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 25008754 25008754 C T SNP PARP4 ENST00000381989 human ensembl 74_37 -1 known missense c.4525 p.E1509K 0 NULL pfam_Poly(ADP-ribose)pol_cat_dom,pfam_VIT,pfam_VWF_A,pfam_BRCT_dom,superfamily_Poly(ADP-ribose)pol_reg_dom,superfamily_BRCT_dom,smart_BRCT_dom,smart_VIT,smart_VWF_A,pfscan_BRCT_dom,pfscan_VWF_A,pfscan_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_reg_dom 0 no_errors 0 0 0 26 0 0 26 9 25.71 135 0 0.00 81 46 36.22 BRCA2 0 genome.wustl.edu 37 13 32968921 32968921 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 32968921 32968921 A G SNP BRCA2 ENST00000380152 human ensembl 74_37 1 known missense c.9352 p.M3118V 0 pfam_BRCA2_OB_3,superfamily_NA-bd_OB-fold,pirsf_BRCA2 pfam_DNA_recomb/repair_BRCA2_hlx,pfam_BRCA2_repeat,pfam_BRCA2_OB_3,pfam_BRCA2_OB_1,pfam_Tower,superfamily_DNA_recomb/repair_BRCA2_hlx,superfamily_NA-bd_OB-fold,pirsf_BRCA2,pfscan_BRCA2_repeat 0 no_errors 0 0 0 148 0 0 69 28 28.87 271 0 0.00 232 96 29.18 NBEA 0 genome.wustl.edu 37 13 35729943 35729943 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 35729943 35729943 A G SNP NBEA ENST00000310336 human ensembl 74_37 1 known silent c.2478 p.V826 0.901 superfamily_ARM-type_fold pfam_BEACH_dom,pfam_DUF1088,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_ConA-like_lec_gl_sf,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 53 0 0 26 11 28.95 181 0 0.00 159 70 30.57 FREM2 0 genome.wustl.edu 37 13 39452457 39452457 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 39452457 39452457 T C SNP FREM2 ENST00000280481 human ensembl 74_37 1 known missense c.8858 p.V2953A 1 NULL pfam_Calx_beta,superfamily_Cadherin-like,smart_Calx_beta 0 no_errors 0 0 0 59 0 0 25 11 30.56 189 0 0.00 213 53 19.92 VWA8 0 genome.wustl.edu 37 13 42481721 42481721 + Splice_Site SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 42481721 42481721 C T SNP VWA8 ENST00000379310 human ensembl 74_37 -1 known splice_site c.483+1 e4+1 1 0 0 0 no_errors 0 0 0 41 0 0 14 10 41.67 152 0 0.00 163 50 23.36 SERP2 0 genome.wustl.edu 37 13 44953801 44953801 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 44953801 44953801 G A SNP SERP2 ENST00000493476 human ensembl 74_37 1 known missense c.109 p.V37M 1 pfam_ER_stress-assoc pfam_ER_stress-assoc 0 no_errors 0 0 0 98 0 0 50 16 24.24 320 0 0.00 221 105 31.91 ZC3H13 0 genome.wustl.edu 37 13 46553965 46553965 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 46553965 46553965 C T SNP ZC3H13 ENST00000242848 human ensembl 74_37 -1 known missense c.1895 p.R632H 1 NULL pfam_Znf_CCCH,smart_Znf_CCCH 0 no_errors 0 0 0 74 0 0 60 16 21.05 229 0 0.00 230 94 29.01 CAB39L 0 genome.wustl.edu 37 13 49906183 49906183 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 49906183 49906183 A G SNP CAB39L ENST00000347776 human ensembl 74_37 -1 known missense c.734 p.M245T 1 pfam_Mo25,superfamily_ARM-type_fold pfam_Mo25,superfamily_ARM-type_fold 0 no_errors 0 0 0 59 0 0 28 13 30.95 240 0 0.00 189 73 27.86 SETDB2 0 genome.wustl.edu 37 13 50056925 50056925 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 50056925 50056925 C T SNP SETDB2 ENST00000317257 human ensembl 74_37 1 known silent c.1245 p.N415 0 pfam_SET_dom,smart_SET_dom,pfscan_SET_dom pfam_SET_dom,pfam_Pre-SET_dom,pfam_Methyl_CpG_DNA-bd,superfamily_DNA-bd_dom,smart_Methyl_CpG_DNA-bd,smart_Pre-SET_Zn-bd_sub,smart_SET_dom,pfscan_Methyl_CpG_DNA-bd,pfscan_SET_dom,pfscan_Pre-SET_dom 0 no_errors 0 0 0 112 0 0 50 9 15.25 233 0 0.00 190 68 26.36 ATP7B 0 genome.wustl.edu 37 13 52520508 52520508 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 52520508 52520508 G A SNP ATP7B ENST00000242839 human ensembl 74_37 -1 known missense c.2972 p.T991M 1 pfam_ATPase_P-typ_transduc_dom_A,tigrfam_Cation_transp_P-typ_ATPase_IB pfam_HeavyMe-assoc_HMA,pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_HeavyMe-assoc_HMA,pfscan_HeavyMe-assoc_HMA,prints_Cation_transp_P_typ_ATPase,tigrfam_Cation_transp_P-typ_ATPase_IB,tigrfam_Cation_transp_P_typ_ATPase,tigrfam_HMA_Cu_ion-bd 0 no_errors rs41292782 G->A 0.9998,0.0001997 37 1 2.63 40 8 16.67 43 0 0.00 36 9 20.00 GPC6 0 genome.wustl.edu 37 13 94197638 94197638 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 94197638 94197638 C T SNP GPC6 ENST00000377047 human ensembl 74_37 1 known missense c.283 p.R95C 0.995 pfam_Glypican pfam_Glypican 0 no_errors 0 0 0 117 0 0 81 35 29.66 239 1 0.42 235 83 26.10 CLDN10 0 genome.wustl.edu 37 13 96205185 96205185 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 96205185 96205185 G A SNP CLDN10 ENST00000299339 human ensembl 74_37 1 known missense c.178 p.V60I 1 pfam_PMP22/EMP/MP20/Claudin pfam_PMP22/EMP/MP20/Claudin,prints_Claudin10,prints_Claudin 0 no_errors 0 0 0 69 0 0 33 25 43.1 124 0 0.00 97 37 27.61 CCDC168 0 genome.wustl.edu 37 13 103387768 103387768 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 103387768 103387768 G A SNP CCDC168 ENST00000322527 human ensembl 74_37 -1 known silent c.1392 p.N464 0 NULL NULL 0 no_errors 0 0 0 74 0 0 36 15 29.41 235 0 0.00 202 75 27.08 ARGLU1 0 genome.wustl.edu 37 13 107211856 107211856 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 107211856 107211856 C T SNP ARGLU1 ENST00000400198 human ensembl 74_37 -1 known missense c.497 p.R166H 1 NULL NULL 0 no_errors 0 0 0 52 0 0 39 20 33.9 163 0 0.00 135 56 29.32 IRS2 0 genome.wustl.edu 37 13 110434873 110434873 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 110434873 110434873 G A SNP IRS2 ENST00000375856 human ensembl 74_37 -1 known silent c.3528 p.S1176 0.016 NULL pfam_Insln_rcpt_S1,pfam_Pleckstrin_homology,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,pfscan_Pleckstrin_homology,pfscan_Insln_rcpt_S1,prints_Insln_rcpt_S1 0 no_errors 0 0 0 24 0 0 16 10 38.46 80 0 0.00 62 29 31.87 ARHGEF7 0 genome.wustl.edu 37 13 111893611 111893611 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 111893611 111893611 G A SNP ARHGEF7 ENST00000483189 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 20 0 0 12 10 45.45 157 0 0.00 133 43 24.29 TUBGCP3 0 genome.wustl.edu 37 13 113140327 113140327 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 113140327 113140327 G A SNP TUBGCP3 ENST00000261965 human ensembl 74_37 -1 known missense c.2704 p.R902W 1 NULL pfam_TUBGCP 0 no_errors rs138098573 G->A 0 54 0 0 33 10 23.26 46 0 0.00 33 9 21.43 PCID2 0 genome.wustl.edu 37 13 113851352 113851352 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 113851352 113851352 C T SNP PCID2 ENST00000246505 human ensembl 74_37 -1 known missense c.406 p.V136I 0 NULL pfam_PCI_dom,smart_PAM 0 no_errors rs368517651 C->T 0 79 0 0 45 19 29.69 266 0 0.00 204 82 28.67 CUL4A 0 genome.wustl.edu 37 13 113887634 113887634 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 113887634 113887634 G A SNP CUL4A ENST00000375440 human ensembl 74_37 1 known missense c.656 p.G219D 1 pfam_Cullin_N,superfamily_Cullin_repeat-like_dom pfam_Cullin_N,pfam_Cullin_neddylation_domain,superfamily_Cullin_repeat-like_dom,superfamily_Cullin_homology,smart_Cullin_homology,smart_Cullin_neddylation_domain,pfscan_Cullin_homology 0 no_errors 0 0 0 61 0 0 29 11 27.5 64 0 0.00 46 11 18.97 GRK1 0 genome.wustl.edu 37 13 114426118 114426118 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 114426118 114426118 G A SNP GRK1 ENST00000335678 human ensembl 74_37 1 known missense c.1057 p.A353T 0.998 pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_RGS_dom,superfamily_Kinase-like_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pfscan_Regulat_G_prot_signal_superfam,pfscan_Prot_kinase_dom,prints_GPCR_kinase 0 no_errors 0 0 0 23 0 0 9 7 43.75 70 0 0.00 68 18 20.93 OR4N2 0 genome.wustl.edu 37 14 20295852 20295852 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 20295852 20295852 T C SNP OR4N2 ENST00000315947 human ensembl 74_37 1 known missense c.245 p.L82S 0.977 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 136 1 0.73 104 21 16.8 59 0 0.00 36 7 16.28 METTL17 0 genome.wustl.edu 37 14 21461287 21461287 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 21461287 21461287 G A SNP METTL17 ENST00000382985 human ensembl 74_37 1 known missense c.539 p.R180Q 0.449 pfam_Ribosomal_Rsm22_bac-type pfam_Ribosomal_Rsm22_bac-type,pfam_Methyltransf_11 0 no_errors rs188874835 G->A 0 50 0 0 31 10 24.39 264 0 0.00 195 111 36.27 ZNF219 0 genome.wustl.edu 37 14 21560534 21560534 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 21560534 21560534 C T SNP ZNF219 ENST00000360947 human ensembl 74_37 -1 known missense c.922 p.G308S 1 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2,prints_Histamine_H3_rcpt 0 no_errors 0 0 0 13 0 0 10 3 23.08 57 0 0.00 55 20 26.67 PRMT5 0 genome.wustl.edu 37 14 23395919 23395919 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 23395919 23395919 C T SNP PRMT5 ENST00000324366 human ensembl 74_37 -1 known silent c.555 p.T185 0.716 pfam_Arg_MeTrfase,pirsf_Arg_MeTrfase_PRMT5 pfam_Arg_MeTrfase,pirsf_Arg_MeTrfase_PRMT5 0 no_errors 0 0 0 49 0 0 28 11 28.21 246 0 0.00 211 77 26.64 CMTM5 0 genome.wustl.edu 37 14 23847585 23847585 + Missense_Mutation SNP T T G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T G T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 23847585 23847585 T G SNP CMTM5 ENST00000339180 human ensembl 74_37 1 known missense c.154 p.F52V 1 NULL NULL 0 no_errors 0 0 0 35 0 0 16 3 15.79 119 0 0.00 82 40 32.79 PCK2 0 genome.wustl.edu 37 14 24572069 24572069 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 24572069 24572069 G A SNP PCK2 ENST00000216780 human ensembl 74_37 1 known missense c.1342 p.A448T 1 pfam_PEP_carboxykinase_GTP,pirsf_PEP_carboxykinase_GTP pfam_PEP_carboxykinase_GTP,superfamily_PEP_carboxykinase_N,pirsf_PEP_carboxykinase_GTP 0 no_errors rs551184706 G->A 0.9998,0.0001997 35 0 0 25 7 21.88 100 0 0.00 106 32 23.02 TGM1 0 genome.wustl.edu 37 14 24729876 24729876 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 24729876 24729876 C T SNP TGM1 ENST00000206765 human ensembl 74_37 -1 known silent c.537 p.T179 0.998 pfam_Transglutaminase_N,superfamily_Ig_E-set pfam_Transglutaminase_C,pfam_Transglutaminase_N,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like 0 no_errors 0 0 0 29 0 0 20 9 31.03 157 0 0.00 124 59 32.24 AKAP6 0 genome.wustl.edu 37 14 33291302 33291302 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 33291302 33291302 C T SNP AKAP6 ENST00000280979 human ensembl 74_37 1 known missense c.4283 p.S1428L 0.991 NULL smart_Spectrin/alpha-actinin 0 no_errors rs537245618 C->T 0.9998,0.0001997 63 0 0 45 16 26.23 289 0 0.00 272 90 24.86 TTC6 0 genome.wustl.edu 37 14 38286843 38286843 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 38286843 38286843 A G SNP TTC6 ENST00000478811 human ensembl 74_37 1 known missense c.943 p.M315V 0.035 smart_TPR_repeat,pfscan_TPR-contain_dom pfam_TPR_1,pfam_TPR_2,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom 0 no_errors rs370029146 A->G 0 40 0 0 26 14 35 144 0 0.00 140 59 29.65 MGAT2 0 genome.wustl.edu 37 14 50088616 50088616 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 50088616 50088616 C T SNP MGAT2 ENST00000305386 human ensembl 74_37 1 known silent c.630 p.C210 1 pfam_GlcNAc_II pfam_GlcNAc_II 0 no_errors 0 0 0 51 0 0 32 17 34.69 201 0 0.00 168 83 33.07 C14orf182 0 genome.wustl.edu 37 14 50472274 50472274 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 50472274 50472274 G A SNP C14orf182 ENST00000529902 human ensembl 74_37 -1 known rna NULL NULL 0.001 0 0 0 no_errors 0 0 0 27 0 0 18 8 29.63 160 0 0.00 139 41 22.78 SYNE2 0 genome.wustl.edu 37 14 64468724 64468724 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 64468724 64468724 G A SNP SYNE2 ENST00000358025 human ensembl 74_37 1 known silent c.3711 p.S1237 0.001 NULL pfam_CH-domain,pfam_KASH,pfam_Spectrin_repeat,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,pfscan_CH-domain,pfscan_KASH 0 no_errors 0 0 0 51 0 0 26 9 25.71 154 0 0.00 149 51 25.50 GALNT16 0 genome.wustl.edu 37 14 69806306 69806306 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 69806306 69806306 G A SNP GALNT16 ENST00000337827 human ensembl 74_37 1 known missense c.1157 p.R386Q 1 NULL pfam_Glyco_trans_2,pfam_Ricin_B_lectin,superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin 0 no_errors 0 0 0 39 0 0 21 4 16 119 0 0.00 103 43 29.25 ADAM21P1 0 genome.wustl.edu 37 14 70713487 70713487 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 70713487 70713487 C T SNP ADAM21P1 ENST00000530196 human ensembl 74_37 -1 known rna NULL NULL 0.003 0 0 0 no_errors 0 0 0 79 1 1.25 38 15 28.3 182 0 0.00 143 74 34.10 MLH3 0 genome.wustl.edu 37 14 75483880 75483880 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 75483880 75483880 G A SNP MLH3 ENST00000355774 human ensembl 74_37 -1 known missense c.4267 p.R1423C 0.989 NULL pfam_MutL_C,pfam_DNA_mismatch_repair_C,pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_WW_dom,smart_MutL_C 0 no_errors 0 0 0 60 0 0 38 26 40.62 245 1 0.41 209 82 28.18 GALC 0 genome.wustl.edu 37 14 88411976 88411976 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 88411976 88411976 G A SNP GALC ENST00000261304 human ensembl 74_37 -1 known missense c.1591 p.R531C 0.997 pfam_Glyco_hydro_59 pfam_Glyco_hydro_59,superfamily_Glycoside_hydrolase_SF,prints_Glyco_hydro_59 0 no_errors 0 0 0 110 0 0 53 32 37.65 200 0 0.00 146 79 35.11 WDR25 0 genome.wustl.edu 37 14 100848025 100848025 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 100848025 100848025 G A SNP WDR25 ENST00000335290 human ensembl 74_37 1 known missense c.764 p.C255Y 1 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 63 0 0 37 12 24.49 195 0 0.00 167 55 24.77 AHNAK2 0 genome.wustl.edu 37 14 105419322 105419322 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 105419322 105419322 G A SNP AHNAK2 ENST00000333244 human ensembl 74_37 -1 known silent c.2466 p.A822 0 NULL superfamily_PDZ,smart_PDZ,pfscan_PDZ 0 no_errors 0 0 0 94 0 0 48 11 18.64 2 0 0.00 4 2 33.33 HERC2 0 genome.wustl.edu 37 15 28441399 28441399 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 28441399 28441399 T A SNP HERC2 ENST00000261609 human ensembl 74_37 -1 known missense c.8222 p.H2741L 1 pfam_Znf_ZZ,superfamily_Galactose-bd-like,smart_Znf_ZZ,pfscan_Znf_ZZ pfam_Reg_chr_condens,pfam_HECT,pfam_CPH_domain,pfam_Mib_Herc2,pfam_Cyt_B5-like_heme/steroid-bd,pfam_Znf_ZZ,pfam_APC_su10/DOC_dom,superfamily_RCC1/BLIP-II,superfamily_HECT,superfamily_Galactose-bd-like,superfamily_Cyt_B5-like_heme/steroid-bd,superfamily_UBA-like,superfamily_CUB_dom,smart_Beta-propeller_rpt_TECPR,smart_Znf_ZZ,smart_HECT,pfscan_HECT,pfscan_Znf_ZZ,pfscan_Reg_chr_condens,pfscan_Cyt_B5-like_heme/steroid-bd,prints_Reg_chr_condens 0 no_errors 0 0 0 233 0 0 131 59 31.05 126 0 0.00 95 50 34.48 WHAMMP2 0 genome.wustl.edu 37 15 28986394 28986394 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 28986394 28986394 C T SNP WHAMMP2 ENST00000508764 human ensembl 74_37 1 putative rna NULL NULL 1 0 0 0 no_errors 0 0 0 313 0 0 162 52 24.19 116 2 1.68 89 40 31.01 FAM189A1 0 genome.wustl.edu 37 15 29429340 29429340 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 29429340 29429340 C T SNP FAM189A1 ENST00000261275 human ensembl 74_37 -1 known missense c.688 p.V230I 0.626 NULL pfam_CD20-like 0 no_errors rs556713434 C->T 0.9998,0.0001997 36 0 0 26 5 16.13 74 0 0.00 55 32 36.78 FMN1 0 genome.wustl.edu 37 15 33357216 33357216 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 33357216 33357216 C T SNP FMN1 ENST00000334528 human ensembl 74_37 -1 known nonsense c.1434 p.W478* 1 prints_Formin_Cappuccino_subfam pfam_FH2_Formin,smart_FH2_Formin,prints_Formin_Cappuccino_subfam 0 no_errors 0 0 0 90 0 0 43 28 39.44 192 0 0.00 169 81 32.40 BAHD1 0 genome.wustl.edu 37 15 40754411 40754411 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 40754411 40754411 C A SNP BAHD1 ENST00000416165 human ensembl 74_37 1 known missense c.1733 p.P578Q 1 NULL pfam_BAH_dom,smart_BAH_dom,pfscan_BAH_dom 0 no_errors 0 0 0 27 1 3.57 12 9 42.86 46 0 0.00 37 13 25.49 RTF1 0 genome.wustl.edu 37 15 41768665 41768665 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 41768665 41768665 T C SNP RTF1 ENST00000389629 human ensembl 74_37 1 known missense c.1504 p.F502L 1 NULL pfam_Plus-3,smart_Plus3-dom_subgr 0 no_errors 0 0 0 112 0 0 65 23 26.14 268 0 0.00 205 76 27.05 ZNF106 0 genome.wustl.edu 37 15 42716969 42716969 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 42716969 42716969 C T SNP ZNF106 ENST00000565660 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 19 0 0 16 7 30.43 108 0 0.00 85 47 35.61 TP53BP1 0 genome.wustl.edu 37 15 43714075 43714075 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 43714075 43714075 G T SNP TP53BP1 ENST00000382044 human ensembl 74_37 -1 known silent c.4078 p.R1360 1 NULL pfam_53-BP1_Tudor,superfamily_BRCT_dom,smart_BRCT_dom,pfscan_BRCT_dom 0 no_errors 0 0 0 27 0 0 19 5 20.83 214 2 0.93 177 58 24.58 SERF2 0 genome.wustl.edu 37 15 44093946 44093946 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 44093946 44093946 G A SNP SERF2 ENST00000594896 human ensembl 74_37 1 known missense c.470 p.R157H 1 NULL NULL 0 no_errors 0 0 0 65 0 0 33 16 32.65 145 0 0.00 126 58 31.52 DUOX1 0 genome.wustl.edu 37 15 45442869 45442869 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 45442869 45442869 G A SNP DUOX1 ENST00000321429 human ensembl 74_37 1 known missense c.2858 p.R953Q 0.987 NULL pfam_Haem_peroxidase_animal,pfam_Fe_red_NAD-bd_6,pfam_FAD-bd_8,pfam_Fe3_Rdtase_TM_dom,pfam_EF_hand_dom,superfamily_Haem_peroxidase,superfamily_Riboflavin_synthase-like_b-brl,smart_EF_hand_dom,prints_Haem_peroxidase_animal_subgr,prints_Recoverin,pfscan_EF_hand_dom,pfscan_Haem_peroxidase_animal 0 no_errors 0 0 0 26 0 0 14 2 12.5 90 0 0.00 44 23 34.33 CGNL1 0 genome.wustl.edu 37 15 57809086 57809086 + Missense_Mutation SNP A A C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A C A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 57809086 57809086 A C SNP CGNL1 ENST00000281282 human ensembl 74_37 1 known missense c.2512 p.S838R 0 prints_Tropomyosin pfam_Myosin_tail,prints_Tropomyosin 0 no_errors 0 0 0 46 0 0 18 10 35.71 81 0 0.00 58 19 24.68 NARG2 0 genome.wustl.edu 37 15 60745781 60745781 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 60745781 60745781 G A SNP NARG2 ENST00000561114 human ensembl 74_37 -1 putative silent c.1146 p.F382 0 NULL NULL 0 no_errors 0 0 0 63 0 0 27 9 23.68 293 0 0.00 246 86 25.83 VPS13C 0 genome.wustl.edu 37 15 62300907 62300907 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 62300907 62300907 C T SNP VPS13C ENST00000261517 human ensembl 74_37 -1 known silent c.1065 p.A355 0.519 NULL pfam_VPSAP_dom,pfam_Autophagy-rel_C 0 no_errors 0 0 0 123 0 0 47 23 32.86 301 0 0.00 254 103 28.77 HERC1 0 genome.wustl.edu 37 15 63967237 63967237 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 63967237 63967237 G A SNP HERC1 ENST00000443617 human ensembl 74_37 -1 known nonsense c.7150 p.R2384* 0.976 NULL pfam_Reg_chr_condens,pfam_HECT,pfam_WD40_repeat,pfam_SPRY_rcpt,superfamily_RCC1/BLIP-II,superfamily_HECT,superfamily_WD40_repeat_dom,superfamily_ConA-like_lec_gl_sf,superfamily_UBA-like,superfamily_ARM-type_fold,smart_SPla/RYanodine_receptor_subgr,smart_WD40_repeat,smart_HECT,pfscan_B30.2/SPRY,pfscan_HECT,pfscan_Reg_chr_condens,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_Reg_chr_condens 0 no_errors 0 0 0 42 0 0 40 11 21.57 160 0 0.00 108 53 32.92 SNX1 0 genome.wustl.edu 37 15 64424072 64424072 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 64424072 64424072 G A SNP SNX1 ENST00000559844 human ensembl 74_37 1 known missense c.1202 p.R401H 1 pfam_Vps5_C pfam_Vps5_C,pfam_Sorting_nexin_N,pfam_Phox,superfamily_Phox,smart_Phox,pfscan_Phox 0 no_errors 0 0 0 39 0 0 19 11 36.67 190 0 0.00 146 69 32.09 TIPIN 0 genome.wustl.edu 37 15 66645207 66645207 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 66645207 66645207 G T SNP TIPIN ENST00000261881 human ensembl 74_37 -1 known missense c.79 p.P27T 1 NULL pfam_Swi3 0 no_errors 0 0 0 84 0 0 44 18 29.03 47 0 0.00 50 25 33.33 ITGA11 0 genome.wustl.edu 37 15 68612623 68612623 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 68612623 68612623 G A SNP ITGA11 ENST00000315757 human ensembl 74_37 -1 known missense c.2516 p.A839V 0.988 pfam_Integrin_alpha-2 pfam_Integrin_alpha-2,pfam_VWF_A,pfam_FG-GAP,smart_Int_alpha_beta-p,smart_VWF_A,pfscan_VWF_A,prints_Integrin_alpha 0 no_errors rs200675726 G->A 0 19 0 0 8 4 33.33 68 0 0.00 58 23 28.40 SCAMP2 0 genome.wustl.edu 37 15 75137863 75137863 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 75137863 75137863 G A SNP SCAMP2 ENST00000268099 human ensembl 74_37 -1 known missense c.806 p.A269V 1 pfam_SCAMP pfam_SCAMP 0 no_errors 0 0 0 28 0 0 12 6 33.33 115 0 0.00 86 31 26.50 C15orf39 0 genome.wustl.edu 37 15 75499654 75499654 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 75499654 75499654 C T SNP C15orf39 ENST00000360639 human ensembl 74_37 1 known missense c.1265 p.A422V 0.008 NULL NULL 0 no_errors rs149666825 C->T 0.9996,0.0003994 40 0 0 20 10 33.33 52 0 0.00 28 7 20.00 GOLGA6D 0 genome.wustl.edu 37 15 75586105 75586105 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 75586105 75586105 C T SNP GOLGA6D ENST00000434739 human ensembl 74_37 1 known silent c.1629 p.D543 0.954 NULL NULL 0 no_errors 0 0 0 83 0 0 36 12 25 29 0 0.00 31 5 13.89 SIN3A 0 genome.wustl.edu 37 15 75706642 75706642 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 75706642 75706642 G A SNP SIN3A ENST00000360439 human ensembl 74_37 -1 known missense c.377 p.A126V 1 superfamily_PAH pfam_PAH,pfam_HDAC_interact,superfamily_PAH,smart_HDAC_interact 0 no_errors 0 0 0 47 1 2.08 22 14 38.89 171 0 0.00 135 47 25.68 ACAN 0 genome.wustl.edu 37 15 89398410 89398410 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 89398410 89398410 A G SNP ACAN ENST00000439576 human ensembl 74_37 1 known missense c.2594 p.D865G 0 NULL pfam_Link,pfam_C-type_lectin,pfam_Ig_V-set,pfam_Sushi_SCR_CCP,pfam_EG-like_dom,superfamily_C-type_lectin_fold,superfamily_Sushi_SCR_CCP,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Link,smart_EG-like_dom,smart_C-type_lectin,smart_Sushi_SCR_CCP,pfscan_EG-like_dom,pfscan_C-type_lectin,pfscan_Link,pfscan_Sushi_SCR_CCP,pfscan_Ig-like_dom,prints_Link 0 no_errors 0 0 0 29 0 0 23 4 14.81 76 1 1.30 60 22 26.83 FANCI 0 genome.wustl.edu 37 15 89858550 89858550 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 15 89858550 89858550 G A SNP FANCI ENST00000310775 human ensembl 74_37 1 known missense c.3854 p.R1285Q 0.639 NULL NULL 0 no_errors rs121918163 G->A 0 52 0 0 29 18 38.3 143 0 0.00 106 29 21.17 MRPL28 0 genome.wustl.edu 37 16 418359 418359 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 418359 418359 G A SNP MRPL28 ENST00000199706 human ensembl 74_37 -1 known missense c.632 p.A211V 1 NULL NULL 0 no_errors 0 0 0 58 0 0 54 16 22.86 110 0 0.00 101 41 28.67 ZNF205 0 genome.wustl.edu 37 16 3169491 3169491 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 3169491 3169491 G A SNP ZNF205 ENST00000219091 human ensembl 74_37 1 known missense c.830 p.R277H 0 NULL pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 30 0 0 14 7 33.33 31 0 0.00 35 10 22.22 ZNF213 0 genome.wustl.edu 37 16 3191340 3191340 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 3191340 3191340 G A SNP ZNF213 ENST00000396878 human ensembl 74_37 1 known missense c.1372 p.V458M 0.98 NULL pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN 0 no_errors 0 0 0 9 0 0 8 8 50 41 0 0.00 29 12 29.27 NLRC3 0 genome.wustl.edu 37 16 3614772 3614772 + RNA SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 3614772 3614772 G T SNP NLRC3 ENST00000603055 human ensembl 74_37 -1 known rna NULL NULL 0.021 0 0 0 no_errors 0 0 0 44 0 0 18 8 30.77 109 0 0.00 73 28 27.72 METTL22 0 genome.wustl.edu 37 16 8738419 8738419 + Missense_Mutation SNP A A C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A C A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 8738419 8738419 A C SNP METTL22 ENST00000381920 human ensembl 74_37 1 known missense c.1016 p.N339T 1 pfam_Nicotinamide_N-MeTfrase-like pfam_Nicotinamide_N-MeTfrase-like 0 no_errors 0 0 0 53 0 0 28 8 22.22 138 0 0.00 108 46 29.87 CLEC16A 0 genome.wustl.edu 37 16 11097045 11097045 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 11097045 11097045 G A SNP CLEC16A ENST00000409790 human ensembl 74_37 1 known missense c.1186 p.V396I 1 NULL pfam_Uncharacterised_FPL 0 no_errors 0 0 0 54 0 0 19 9 32.14 107 0 0.00 103 39 27.46 ABCC6 0 genome.wustl.edu 37 16 16315498 16315498 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 16315498 16315498 G A SNP ABCC6 ENST00000575728 human ensembl 74_37 -1 putative missense c.227 p.A76V 0 NULL NULL 0 no_errors 0 0 0 85 0 0 52 18 25.71 134 0 0.00 108 56 34.15 NOMO3 0 genome.wustl.edu 37 16 16338949 16338949 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 16338949 16338949 G T SNP NOMO3 ENST00000399336 human ensembl 74_37 1 known missense c.427 p.G143C 1 superfamily_CarboxyPept-like_regulatory pfam_DUF2012,superfamily_CarboxyPept-like_regulatory,superfamily_Carb-bd-like_fold,superfamily_Collagen-bd_Cna_B-typ_dom 0 no_errors 0 0 0 31 0 0 14 6 30 13 0 0.00 7 3 30.00 CD19 0 genome.wustl.edu 37 16 28944391 28944391 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 28944391 28944391 C T SNP CD19 ENST00000538922 human ensembl 74_37 1 known missense c.515 p.P172L 0 NULL smart_Ig_sub,pfscan_Ig-like_dom 0 no_errors 0 0 0 12 0 0 9 3 25 97 0 0.00 82 37 31.09 ZNF629 0 genome.wustl.edu 37 16 30793648 30793648 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 30793648 30793648 G A SNP ZNF629 ENST00000262525 human ensembl 74_37 -1 known silent c.2001 p.C667 0.949 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 37 0 0 28 10 26.32 79 0 0.00 74 27 26.73 ITGAD 0 genome.wustl.edu 37 16 31408919 31408919 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 31408919 31408919 C T SNP ITGAD ENST00000389202 human ensembl 74_37 1 known missense c.244 p.R82C 0.071 NULL pfam_Integrin_alpha-2,pfam_VWF_A,pfam_Integrin_alpha_C_CS,smart_Int_alpha_beta-p,smart_VWF_A,pfscan_VWF_A,prints_Integrin_alpha 0 no_errors 0 0 0 46 0 0 26 12 31.58 83 0 0.00 56 20 26.32 TP53TG3D 0 genome.wustl.edu 37 16 32265819 32265819 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 32265819 32265819 T C SNP TP53TG3D ENST00000564810 human ensembl 74_37 1 known rna NULL NULL 0.244 0 0 0 no_errors 0 0 0 55 0 0 16 31 65.96 42 0 0.00 15 25 62.50 NKD1 0 genome.wustl.edu 37 16 50583397 50583397 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 50583397 50583397 G A SNP NKD1 ENST00000268459 human ensembl 74_37 1 known silent c.123 p.Q41 1 NULL pfscan_EF_hand_dom 0 no_errors 0 0 0 66 0 0 37 21 36.21 34 0 0.00 18 7 28.00 CNGB1 0 genome.wustl.edu 37 16 57953050 57953050 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 57953050 57953050 C T SNP CNGB1 ENST00000251102 human ensembl 74_37 -1 known missense c.1910 p.R637H 1 NULL pfam_cNMP-bd_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom 0 no_errors 0 0 0 66 0 0 25 22 46.81 162 0 0.00 77 54 41.22 CNOT1 0 genome.wustl.edu 37 16 58580623 58580623 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 58580623 58580623 C T SNP CNOT1 ENST00000317147 human ensembl 74_37 -1 known missense c.3781 p.A1261T 1 NULL pfam_CCR4-Not_Not1_C,superfamily_ARM-type_fold 0 no_errors 0 0 0 51 0 0 14 11 44 282 0 0.00 154 90 36.89 CES2 0 genome.wustl.edu 37 16 66974547 66974547 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 66974547 66974547 C T SNP CES2 ENST00000317091 human ensembl 74_37 1 known silent c.957 p.G319 0.457 pfam_CarbesteraseB pfam_CarbesteraseB,pfam_AB_hydrolase_3 0 no_errors rs556416386 C->T 0.9996,0.0003994 28 0 0 6 5 45.45 107 0 0.00 43 23 34.85 ZFHX3 0 genome.wustl.edu 37 16 72828653 72828653 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 72828653 72828653 C T SNP ZFHX3 ENST00000268489 human ensembl 74_37 -1 known missense c.7928 p.R2643H 1 pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom pfam_Homeobox_dom,superfamily_Homeodomain-like,superfamily_Adenylate_cyclase-assoc_CAP_N,smart_Znf_C2H2-like,smart_Znf_U1,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Znf_C2H2 0 no_errors 0 0 0 65 0 0 24 9 27.27 243 2 0.81 134 45 25.14 JPH3 0 genome.wustl.edu 37 16 87730277 87730277 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 87730277 87730277 C T SNP JPH3 ENST00000537256 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 53 0 0 15 5 25 157 0 0.00 84 39 31.45 PABPN1L 0 genome.wustl.edu 37 16 88930697 88930697 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 88930697 88930697 G T SNP PABPN1L ENST00000427766 human ensembl 74_37 -1 known missense c.638 p.P213H 0.014 NULL NULL 0 no_errors 0 0 0 20 0 0 13 6 31.58 80 0 0.00 38 23 37.70 CPNE7 0 genome.wustl.edu 37 16 89653462 89653462 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 89653462 89653462 G A SNP CPNE7 ENST00000268720 human ensembl 74_37 1 known silent c.1104 p.V368 0.996 NULL pfam_Copine,pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,smart_VWF_A,pfscan_C2_dom,pfscan_VWF_A 0 no_errors 0 0 0 49 0 0 20 11 35.48 37 0 0.00 15 10 40.00 WDR81 0 genome.wustl.edu 37 17 1629622 1629622 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 1629622 1629622 C T SNP WDR81 ENST00000409644 human ensembl 74_37 1 known missense c.1369 p.R457C 1 pfam_BEACH_dom,superfamily_BEACH_dom,pfscan_BEACH_dom pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_Kinase-like_dom,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 10 0 0 11 4 26.67 41 0 0.00 52 13 20.00 WDR81 0 genome.wustl.edu 37 17 1637359 1637359 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 1637359 1637359 G A SNP WDR81 ENST00000409644 human ensembl 74_37 1 known silent c.5028 p.P1676 0.047 superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat_dom pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_Kinase-like_dom,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 33 0 0 12 3 20 26 0 0.00 21 13 37.14 OR3A1 0 genome.wustl.edu 37 17 3195464 3195464 + Missense_Mutation SNP C C G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C G C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 3195464 3195464 C G SNP OR3A1 ENST00000323404 human ensembl 74_37 -1 known missense c.413 p.R138P 0.004 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 47 0 0 32 16 33.33 61 0 0.00 45 11 19.64 OR1E1 0 genome.wustl.edu 37 17 3301569 3301569 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 3301569 3301569 T C SNP OR1E1 ENST00000322608 human ensembl 74_37 -1 known missense c.136 p.I46V 0.175 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 67 0 0 30 15 33.33 90 0 0.00 66 20 23.26 ENSG00000262823 0 genome.wustl.edu 37 17 4389637 4389637 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 4389637 4389637 G A SNP ENSG00000262823 ENST00000576086 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors rs552540587 G->A 0.9998,0.0001997 40 0 0 24 6 20 83 0 0.00 63 28 30.77 WSCD1 0 genome.wustl.edu 37 17 5984033 5984033 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 5984033 5984033 C T SNP WSCD1 ENST00000317744 human ensembl 74_37 1 known silent c.55 p.L19 1 NULL pfam_WSC_carb-bd,pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase,smart_WSC_carb-bd_subgr,pfscan_WSC_carb-bd 0 no_errors 0 0 0 42 0 0 28 4 12.5 106 0 0.00 88 46 34.07 SLC13A5 0 genome.wustl.edu 37 17 6609990 6609990 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 6609990 6609990 C T SNP SLC13A5 ENST00000433363 human ensembl 74_37 -1 known silent c.339 p.T113 0.897 pfam_Na/sul_symport,pfam_Cit_transptr-like_dom pfam_Na/sul_symport,pfam_Cit_transptr-like_dom 0 no_errors 0 0 0 27 0 0 2 4 66.67 70 0 0.00 54 24 30.77 TP53 0 genome.wustl.edu 37 17 7577121 7577121 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 7577121 7577121 G A SNP TP53 ENST00000269305 human ensembl 74_37 -1 known missense c.817 p.R273C 0.83 pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor 0 no_errors rs121913343 G->A 0 15 1 6.25 11 5 31.25 161 1 0.60 141 47 25.00 DNAH2 0 genome.wustl.edu 37 17 7720010 7720010 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 7720010 7720010 C T SNP DNAH2 ENST00000389173 human ensembl 74_37 1 known missense c.9851 p.S3284L 0.94 NULL pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA_core,superfamily_P-loop_NTPase,smart_AAA+_ATPase 0 no_errors rs140494502 C->T 0 58 0 0 26 6 18.75 117 0 0.00 81 35 30.17 GUCY2D 0 genome.wustl.edu 37 17 7915475 7915475 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 7915475 7915475 G A SNP GUCY2D ENST00000254854 human ensembl 74_37 1 known missense c.1763 p.R588Q 1 pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Tyr_kinase_cat_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom pfam_A/G_cyclase,pfam_ANF_lig-bd_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Haem_no_assoc-bd,superfamily_Peripla_BP_I,superfamily_A/G_cyclase,superfamily_Kinase-like_dom,smart_Tyr_kinase_cat_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_A/G_cyclase,pfscan_Prot_kinase_dom,pfscan_A/G_cyclase,prints_Ser-Thr/Tyr_kinase_cat_dom 0 no_errors 0 0 0 20 0 0 9 3 25 113 0 0.00 75 54 41.86 MYH13 0 genome.wustl.edu 37 17 10227551 10227551 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 10227551 10227551 G A SNP MYH13 ENST00000252172 human ensembl 74_37 -1 known missense c.2722 p.R908W 1 NULL pfam_Myosin_tail,pfam_Myosin_head_motor_dom,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 69 0 0 36 8 18.18 267 0 0.00 210 94 30.92 SCO1 0 genome.wustl.edu 37 17 10595204 10595204 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 10595204 10595204 C T SNP SCO1 ENST00000255390 human ensembl 74_37 -1 known missense c.640 p.A214T 1 pfam_SCO1/SenC,pfam_AhpC/TSA,superfamily_Thioredoxin-like_fold,pirsf_Synth_of_cyt-c-oxidase_Sco1/2 pfam_SCO1/SenC,pfam_AhpC/TSA,superfamily_Thioredoxin-like_fold,pirsf_Synth_of_cyt-c-oxidase_Sco1/2 0 no_errors rs145764824 C->T 0 82 0 0 49 18 26.87 267 1 0.37 194 76 28.15 ZNF286A 0 genome.wustl.edu 37 17 15619437 15619437 + Silent SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 15619437 15619437 A G SNP ZNF286A ENST00000413242 human ensembl 74_37 1 known silent c.399 p.S133 0.005 NULL pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 83 0 0 53 19 26.39 121 0 0.00 124 49 28.32 SREBF1 0 genome.wustl.edu 37 17 17726853 17726853 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 17726853 17726853 C A SNP SREBF1 ENST00000355815 human ensembl 74_37 -1 known missense c.160 p.A54S 0.973 NULL pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom 0 no_errors 0 0 0 128 0 0 67 24 26.37 134 0 0.00 106 35 24.82 LGALS9C 0 genome.wustl.edu 37 17 18396087 18396087 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 18396087 18396087 C T SNP LGALS9C ENST00000328114 human ensembl 74_37 1 known missense c.838 p.R280C 0.999 pfam_Galectin_CRD,superfamily_ConA-like_lec_gl_sf,smart_Galectin_CRD pfam_Galectin_CRD,superfamily_ConA-like_lec_gl_sf,smart_Galectin_CRD 0 no_errors rs199959851 C->T 0.9998,0.0001997 33 0 0 10 13 56.52 15 0 0.00 8 10 55.56 TRIM16L 0 genome.wustl.edu 37 17 18638283 18638283 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 18638283 18638283 A T SNP TRIM16L ENST00000395902 human ensembl 74_37 1 known missense c.719 p.E240V 1 superfamily_ConA-like_lec_gl_sf,smart_PRY,pfscan_B30.2/SPRY pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_PRY,smart_SPla/RYanodine_receptor_subgr,prints_Butyrophylin,pfscan_B30.2/SPRY 0 no_errors 0 0 0 53 0 0 31 5 13.89 125 0 0.00 157 15 8.72 SLC47A2 0 genome.wustl.edu 37 17 19582127 19582127 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 19582127 19582127 C T SNP SLC47A2 ENST00000325411 human ensembl 74_37 -1 known missense c.1681 p.A561T 0 NULL pfam_MATE,tigrfam_MATE 0 no_errors rs113234335 C->T 0 42 0 0 28 14 33.33 140 0 0.00 109 25 18.66 FAM27L 0 genome.wustl.edu 37 17 21825494 21825494 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 21825494 21825494 G A SNP FAM27L ENST00000426869 human ensembl 74_37 1 known rna NULL NULL 0.004 0 0 0 no_errors 0 0 0 52 1 1.89 27 11 28.95 42 0 0.00 46 19 29.23 NLK 0 genome.wustl.edu 37 17 26370220 26370220 + Silent SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 26370220 26370220 A T SNP NLK ENST00000407008 human ensembl 74_37 1 known silent c.321 p.A107 0.979 NULL pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 141 0 0 78 40 33.9 53 0 0.00 43 22 33.85 KIAA0100 0 genome.wustl.edu 37 17 26961698 26961698 + Silent SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 26961698 26961698 T C SNP KIAA0100 ENST00000528896 human ensembl 74_37 -1 known silent c.2907 p.A969 0.969 NULL pfam_FMP27_C,pfam_FMP27_N,pfam_FMP27_GFWDK_dom 0 no_errors 0 0 0 38 0 0 24 12 33.33 98 0 0.00 73 41 35.96 CRYBA1 0 genome.wustl.edu 37 17 27580800 27580800 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 27580800 27580800 C T SNP CRYBA1 ENST00000225387 human ensembl 74_37 1 known missense c.500 p.A167V 1 pfam_Beta/gamma_crystallin,superfamily_G_crystallin-rel,smart_Beta/gamma_crystallin,pfscan_Beta/gamma_crystallin pfam_Beta/gamma_crystallin,superfamily_G_crystallin-rel,smart_Beta/gamma_crystallin,pfscan_Beta/gamma_crystallin,prints_Beta/gamma_crystallin 0 no_errors 0 0 0 106 0 0 73 23 23.71 307 2 0.65 241 91 27.33 ERBB2 0 genome.wustl.edu 37 17 37881075 37881075 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 37881075 37881075 C T SNP ERBB2 ENST00000269571 human ensembl 74_37 1 known missense c.2404 p.P802S 1 pirsf_Tyr_kinase_EGF/ERB/XmrK_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom pirsf_Tyr_kinase_EGF/ERB/XmrK_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_EGF_rcpt_L,pfam_Prot_kinase_dom,pfam_Furin-like_Cys-rich_dom,superfamily_Kinase-like_dom,superfamily_Growth_fac_rcpt_N_dom,smart_Furin_repeat,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 52 0 0 43 7 14 90 0 0.00 87 13 13.00 JUP 0 genome.wustl.edu 37 17 39775850 39775850 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 39775850 39775850 C T SNP JUP ENST00000540235 human ensembl 74_37 -1 known missense c.1772 p.R591H 0.762 NULL pfam_IF,pfam_Armadillo,superfamily_ARM-type_fold,superfamily_Prefoldin,smart_Armadillo,pfscan_Armadillo,prints_Keratin_I,prints_Beta-catenin 0 no_errors 0 0 0 96 0 0 55 16 22.54 17 0 0.00 5 5 50.00 DNAJC7 0 genome.wustl.edu 37 17 40146920 40146920 + Nonsense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 40146920 40146920 C A SNP DNAJC7 ENST00000457167 human ensembl 74_37 -1 known nonsense c.448 p.E150* 1 pfscan_TPR-contain_dom pfam_TPR_1,pfam_TPR_2,pfam_DnaJ_domain,superfamily_DnaJ_domain,smart_TPR_repeat,smart_DnaJ_domain,pfscan_TPR_repeat,pfscan_TPR-contain_dom,pfscan_DnaJ_domain,prints_DnaJ_domain 0 no_errors 0 0 0 70 0 0 38 17 30.91 245 0 0.00 205 109 34.71 NKIRAS2 0 genome.wustl.edu 37 17 40174435 40174435 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 40174435 40174435 C T SNP NKIRAS2 ENST00000307641 human ensembl 74_37 1 known missense c.113 p.T38M 1 pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,tigrfam_Small_GTP-bd_dom pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom 0 no_errors 0 0 0 30 0 0 13 10 43.48 137 0 0.00 106 39 26.90 DHX58 0 genome.wustl.edu 37 17 40262881 40262881 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 40262881 40262881 C T SNP DHX58 ENST00000251642 human ensembl 74_37 -1 known missense c.421 p.V141I 0.995 pfam_Helicase/UvrB_dom,pfam_DNA/RNA_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd pfam_RIG-I_C-RD,pfam_Helicase/UvrB_dom,pfam_Helicase_C,pfam_DNA/RNA_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C 0 no_errors rs150385537 C->T 0.9998,0.0001997 28 0 0 14 9 39.13 143 0 0.00 92 48 34.29 STAT5B 0 genome.wustl.edu 37 17 40369192 40369192 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 40369192 40369192 C A SNP STAT5B ENST00000293328 human ensembl 74_37 -1 known missense c.1366 p.V456F 1 pfam_STAT_TF_DNA-bd,superfamily_p53-like_TF_DNA-bd pfam_STAT_TF_DNA-bd,pfam_STAT_TF_alpha,pfam_STAT_TF_prot_interaction,pfam_SH2,superfamily_p53-like_TF_DNA-bd,superfamily_STAT_TF_coiled-coil,superfamily_STAT_TF_prot_interaction,smart_STAT_TF_prot_interaction,smart_SH2,pfscan_SH2 0 no_errors 0 0 0 76 0 0 40 17 29.82 293 0 0.00 218 94 30.13 TUBG2 0 genome.wustl.edu 37 17 40815025 40815025 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 40815025 40815025 C T SNP TUBG2 ENST00000251412 human ensembl 74_37 1 known missense c.434 p.T145M 0.994 pfam_Tubulin_FtsZ_GTPase,superfamily_Tubulin_FtsZ_GTPase,smart_Tubulin_FtsZ_GTPase,prints_Tubulin pfam_Tubulin_FtsZ_GTPase,pfam_Tubulin/FtsZ_2-layer-sand-dom,pfam_Misato_II_tubulin-like,superfamily_Tubulin_FtsZ_GTPase,superfamily_Tub_FtsZ_C,smart_Tubulin_FtsZ_GTPase,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Gamma_tubulin,prints_Tubulin,prints_Epsilon_tubulin,prints_Delta_tubulin,prints_Beta_tubulin,prints_Alpha_tubulin 0 no_errors 0 0 0 33 0 0 12 7 36.84 155 0 0.00 134 54 28.72 CDC27 0 genome.wustl.edu 37 17 45234694 45234694 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 45234694 45234694 T C SNP CDC27 ENST00000531206 human ensembl 74_37 -1 known missense c.532 p.N178D 1 NULL pfam_TPR_1,pfam_TPR_2,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom 0 no_errors 0 0 0 49 0 0 37 15 28.85 61 0 0.00 62 25 28.74 ITGB3 0 genome.wustl.edu 37 17 45360742 45360742 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 45360742 45360742 G A SNP ITGB3 ENST00000559488 human ensembl 74_37 1 known missense c.188 p.R63H 1 pirsf_Integrin_bsu,pfam_Integrin_bsu_N,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N pirsf_Integrin_bsu,pfam_Integrin_bsu_N,pfam_Integrin_bsu_cyt_dom,pfam_Integrin_bsu_tail,pfam_EGF_extracell,superfamily_Integrin_bsu_tail,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N,prints_Integrin_bsu 0 no_errors rs370054364 G->A 0 41 0 0 17 5 21.74 112 1 0.88 83 38 31.15 HOXB5 0 genome.wustl.edu 37 17 46670666 46670666 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 46670666 46670666 T C SNP HOXB5 ENST00000239151 human ensembl 74_37 -1 known missense c.379 p.S127G 0.998 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa,prints_Homeobox_antennapedia 0 no_errors 0 0 0 49 0 0 43 15 25.42 86 0 0.00 59 14 19.18 EPN3 0 genome.wustl.edu 37 17 48613920 48613920 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 48613920 48613920 G A SNP EPN3 ENST00000537145 human ensembl 74_37 1 known missense c.250 p.D84N 1 smart_Epsin-like_N,pfscan_Epsin-like_N pfam_Epsin_dom_N,superfamily_ENTH_VHS,smart_Epsin-like_N,pfscan_Epsin-like_N,pfscan_Ubiquitin-int_motif 0 no_errors 0 0 0 24 0 0 8 8 50 38 0 0.00 41 20 32.79 OR4D2 0 genome.wustl.edu 37 17 56247089 56247089 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 56247089 56247089 C T SNP OR4D2 ENST00000545221 human ensembl 74_37 1 known missense c.73 p.R25C 0.564 NULL pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 42 0 0 33 16 32.65 210 0 0.00 183 58 23.77 LPO 0 genome.wustl.edu 37 17 56321401 56321401 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 56321401 56321401 C T SNP LPO ENST00000262290 human ensembl 74_37 1 known silent c.123 p.A41 0.986 NULL pfam_Haem_peroxidase_animal,superfamily_Haem_peroxidase,pfscan_Haem_peroxidase_animal,prints_Haem_peroxidase_animal_subgr 0 no_errors 0 0 0 30 0 0 17 8 32 95 0 0.00 81 32 28.32 RAD51C 0 genome.wustl.edu 37 17 56770051 56770051 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 56770051 56770051 G A SNP RAD51C ENST00000337432 human ensembl 74_37 1 known missense c.47 p.S16N 0.995 superfamily_DNA_repair_Rad51/TF_NusA_a-hlx,pirsf_DNA_recomb/repair_RecA-like pfam_DNA_recomb/repair_Rad51_C,pfam_Circ_KaiC/RadA,superfamily_P-loop_NTPase,superfamily_DNA_repair_Rad51/TF_NusA_a-hlx,pirsf_DNA_recomb/repair_RecA-like,pfscan_DNA_recomb_RecA/RadB_ATP-bd 0 no_errors 0 0 0 29 0 0 32 9 21.95 130 0 0.00 128 64 33.33 MRC2 0 genome.wustl.edu 37 17 60743591 60743591 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 60743591 60743591 C T SNP MRC2 ENST00000303375 human ensembl 74_37 1 known silent c.657 p.Y219 0.398 pfam_FN_type2_col-bd,superfamily_Kringle-like,smart_FN_type2_col-bd,pfscan_FN_type2_col-bd pfam_C-type_lectin,pfam_FN_type2_col-bd,pfam_Herpes_UL45-like,superfamily_C-type_lectin_fold,superfamily_Ricin_B_lectin,superfamily_Kringle-like,smart_Ricin_B_lectin,smart_FN_type2_col-bd,smart_C-type_lectin,pfscan_FN_type2_col-bd,pfscan_C-type_lectin,pfscan_Ricin_B_lectin,prints_AntifreezeII 0 no_errors rs564657391 C->T 0 25 0 0 19 11 36.67 51 0 0.00 29 14 32.56 TSEN54 0 genome.wustl.edu 37 17 73518111 73518111 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 73518111 73518111 G A SNP TSEN54 ENST00000333213 human ensembl 74_37 1 known missense c.949 p.A317T 0.716 NULL NULL 0 no_errors rs201125812 G->A,T 0.9996,.,0.0003994 13 0 0 10 3 23.08 60 0 0.00 53 14 20.90 TRIM65 0 genome.wustl.edu 37 17 73888095 73888095 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 73888095 73888095 C T SNP TRIM65 ENST00000269383 human ensembl 74_37 -1 known missense c.916 p.V306M 0 superfamily_ConA-like_lec_gl_sf pfam_SPRY_rcpt,pfam_Znf_C3HC4_RING-type,pfam_Znf_B-box,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin 0 no_errors 0 0 0 15 0 0 18 4 18.18 36 0 0.00 33 11 25.00 AFMID 0 genome.wustl.edu 37 17 76202113 76202113 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 76202113 76202113 G T SNP AFMID ENST00000327898 human ensembl 74_37 1 known missense c.882 p.K294N 0.04 NULL pfam_AB_hydrolase_3 0 no_errors 0 0 0 30 0 0 16 8 33.33 156 0 0.00 104 37 26.24 DNAH17 0 genome.wustl.edu 37 17 76522783 76522783 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 76522783 76522783 C T SNP DNAH17 ENST00000389840 human ensembl 74_37 -1 known missense c.3661 p.E1221K 0.169 NULL pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_HR1_rho-bd 0 no_errors 0 0 0 67 0 0 33 9 21.43 137 0 0.00 106 44 29.33 CCDC40 0 genome.wustl.edu 37 17 78069070 78069070 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 78069070 78069070 C T SNP CCDC40 ENST00000397545 human ensembl 74_37 1 known silent c.2841 p.L947 0 NULL pfam_E3_ubiquit_lig_BRE1 0 no_errors rs573028412 C->T 0.9998,0.0001997 67 0 0 43 15 25.86 35 0 0.00 40 12 23.08 RNF213 0 genome.wustl.edu 37 17 78247137 78247137 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 78247137 78247137 G A SNP RNF213 ENST00000582970 human ensembl 74_37 1 known silent c.195 p.P65 0 NULL superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_Znf_RING,pfscan_Znf_RING 0 no_errors rs370520790 G->A 0 38 0 0 7 3 30 149 0 0.00 138 43 23.63 C17orf62 0 genome.wustl.edu 37 17 80401910 80401910 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 80401910 80401910 A G SNP C17orf62 ENST00000336995 human ensembl 74_37 -1 known missense c.89 p.V30A 0.904 NULL NULL 0 no_errors 0 0 0 41 0 0 30 8 21.05 48 0 0.00 58 4 6.45 CXADRP3 0 genome.wustl.edu 37 18 14478350 14478350 + RNA SNP C C G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C G C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 18 14478350 14478350 C G SNP CXADRP3 ENST00000581457 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 63 0 0 25 13 34.21 44 0 0.00 36 18 33.33 RBBP8 0 genome.wustl.edu 37 18 20606151 20606151 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 18 20606151 20606151 G A SNP RBBP8 ENST00000327155 human ensembl 74_37 1 known missense c.2642 p.R881H 1 NULL pfam_CtIP_N,pfam_DNA-repair_Sae2/CtIP 0 no_errors 0 0 0 69 0 0 36 12 25 307 1 0.32 236 80 25.24 ELAC1 0 genome.wustl.edu 37 18 48500887 48500887 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 18 48500887 48500887 G T SNP ELAC1 ENST00000269466 human ensembl 74_37 1 known missense c.113 p.G38V 1 pfam_Beta-lactamas-like,tigrfam_RNase_Z pfam_Beta-lactamas-like,tigrfam_RNase_Z 0 no_errors 0 0 0 87 0 0 55 14 20 202 2 0.98 204 35 14.64 SALL3 0 genome.wustl.edu 37 18 76755157 76755157 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 18 76755157 76755157 G A SNP SALL3 ENST00000537592 human ensembl 74_37 1 known missense c.3166 p.A1056T 0.943 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors rs139036373 G->A 0 55 0 0 33 11 25 122 0 0.00 118 33 21.71 NFATC1 0 genome.wustl.edu 37 18 77171098 77171098 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 18 77171098 77171098 C T SNP NFATC1 ENST00000427363 human ensembl 74_37 1 known missense c.823 p.P275S 0.982 NULL pfam_RHD,pfam_IPT,superfamily_p53-like_TF_DNA-bd,superfamily_Ig_E-set,smart_IPT,pfscan_RHD,prints_NFAT 0 no_errors 0 0 0 11 0 0 11 2 15.38 65 0 0.00 50 22 30.56 REXO1 0 genome.wustl.edu 37 19 1828492 1828492 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 1828492 1828492 C T SNP REXO1 ENST00000170168 human ensembl 74_37 -1 known missense c.296 p.R99H 0.958 NULL pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease 0 no_errors 0 0 0 53 0 0 20 10 33.33 47 0 0.00 20 19 48.72 MOB3A 0 genome.wustl.edu 37 19 2078278 2078278 + Silent SNP G G C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G C G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 2078278 2078278 G C SNP MOB3A ENST00000357066 human ensembl 74_37 -1 known silent c.282 p.G94 0.999 pfam_Mob1_phocein,superfamily_Mob1_phocein pfam_Mob1_phocein,superfamily_Mob1_phocein 0 no_errors 0 0 0 68 0 0 44 23 34.33 90 0 0.00 99 38 27.74 TMPRSS9 0 genome.wustl.edu 37 19 2421915 2421915 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 2421915 2421915 G A SNP TMPRSS9 ENST00000332578 human ensembl 74_37 1 known missense c.2116 p.V706M 0.999 pirsf_Pept_S1A_polyserase-1,pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1 pirsf_Pept_S1A_polyserase-1,pfam_Peptidase_S1,pfam_Peptidase_S1A_nudel,pfam_LDrepeatLR_classA_rpt,superfamily_Trypsin-like_Pept_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_Peptidase_S1,prints_Peptidase_S1A,pfscan_LDrepeatLR_classA_rpt,pfscan_Peptidase_S1 0 no_errors 0 0 0 61 0 0 47 14 22.95 156 0 0.00 146 59 28.64 TBXA2R 0 genome.wustl.edu 37 19 3595731 3595731 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 3595731 3595731 C T SNP TBXA2R ENST00000589966 human ensembl 74_37 -1 putative missense c.598 p.A200T 0 NULL pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Thbox_rcpt,prints_Prostanoid_rcpt 0 no_errors 0 0 0 31 0 0 20 8 28.57 31 0 0.00 17 15 46.88 MIR7-3HG 0 genome.wustl.edu 37 19 4769629 4769629 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 4769629 4769629 C T SNP MIR7-3HG ENST00000589639 human ensembl 74_37 1 known rna NULL NULL 0.004 0 0 0 no_errors 0 0 0 40 0 0 19 13 40.62 98 0 0.00 108 45 29.41 SAFB 0 genome.wustl.edu 37 19 5667070 5667070 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 5667070 5667070 G A SNP SAFB ENST00000588852 human ensembl 74_37 1 known missense c.2348 p.R783H 1 NULL pfam_RRM_dom,pfam_SAP_dom,smart_SAP_dom,smart_RRM_dom,pfscan_SAP_dom,pfscan_RRM_dom 0 no_errors rs368894379 G->A 0 38 0 0 38 10 20 88 0 0.00 78 35 30.70 MLLT1 0 genome.wustl.edu 37 19 6262264 6262264 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 6262264 6262264 G T SNP MLLT1 ENST00000252674 human ensembl 74_37 -1 known missense c.251 p.P84H 1 pfam_YEATS,pfscan_YEATS pfam_YEATS,pfscan_YEATS 0 no_errors 0 0 0 28 0 0 15 5 25 148 0 0.00 151 32 17.39 GTF2F1 0 genome.wustl.edu 37 19 6387532 6387532 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 6387532 6387532 G A SNP GTF2F1 ENST00000394456 human ensembl 74_37 -1 known missense c.365 p.T122M 1 pfam_TFIIF-alpha,superfamily_TFIIF_interaction pfam_TFIIF-alpha,superfamily_TFIIF_interaction 0 no_errors 0 0 0 41 0 0 13 4 23.53 165 0 0.00 99 48 32.65 ZNF358 0 genome.wustl.edu 37 19 7585762 7585762 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 7585762 7585762 G A SNP ZNF358 ENST00000394341 human ensembl 74_37 1 known missense c.1634 p.S545N 0.755 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 32 0 0 14 12 46.15 82 0 0.00 81 40 33.06 PCP2 0 genome.wustl.edu 37 19 7697344 7697344 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 7697344 7697344 G A SNP PCP2 ENST00000311069 human ensembl 74_37 -1 known missense c.226 p.R76C 1 pfam_GoLoco_motif,smart_GoLoco_motif,pfscan_GoLoco_motif pfam_GoLoco_motif,smart_GoLoco_motif,pfscan_GoLoco_motif 0 no_errors 0 0 0 30 0 0 5 15 75 75 0 0.00 58 11 15.94 ENSG00000268149 0 genome.wustl.edu 37 19 7977638 7977638 + RNA SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 7977638 7977638 C A SNP ENSG00000268149 ENST00000595655 human ensembl 74_37 -1 known rna NULL NULL 0.154 0 0 0 no_errors 0 0 0 23 0 0 11 6 35.29 29 0 0.00 20 10 33.33 RGL3 0 genome.wustl.edu 37 19 11508234 11508234 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 11508234 11508234 C T SNP RGL3 ENST00000393423 human ensembl 74_37 -1 known missense c.1804 p.A602T 0 NULL pfam_RasGRF_CDC25,pfam_Ras-assoc,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,smart_Ras-assoc,pfscan_Ras-assoc,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N 0 no_errors 0 0 0 33 0 0 42 7 14.29 13 0 0.00 18 2 10.00 ZNF441 0 genome.wustl.edu 37 19 11878013 11878013 + Splice_Site SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 11878013 11878013 T C SNP ZNF441 ENST00000357901 human ensembl 74_37 1 known splice_site c.3+2 e1+2 0.152 0 0 0 no_errors 0 0 0 143 0 0 122 14 10.29 109 1 0.91 112 11 8.87 CCDC130 0 genome.wustl.edu 37 19 13869851 13869851 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 13869851 13869851 G T SNP CCDC130 ENST00000589096 human ensembl 74_37 1 putative missense c.130 p.G44W 0 NULL pfam_CWC16 0 no_errors 0 0 0 31 0 0 24 9 27.27 19 0 0.00 29 14 32.56 BRD4 0 genome.wustl.edu 37 19 15350575 15350575 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 15350575 15350575 T C SNP BRD4 ENST00000263377 human ensembl 74_37 -1 known missense c.3340 p.K1114E 1 NULL pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,pfscan_Bromodomain,prints_Bromodomain 0 no_errors 0 0 0 25 0 0 14 7 33.33 55 0 0.00 22 13 37.14 OR10H5 0 genome.wustl.edu 37 19 15905529 15905529 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 15905529 15905529 C T SNP OR10H5 ENST00000308940 human ensembl 74_37 1 known missense c.671 p.A224V 0.008 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 43 0 0 31 12 27.91 152 0 0.00 124 42 25.30 UNC13A 0 genome.wustl.edu 37 19 17759402 17759402 + Missense_Mutation SNP T T A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T A T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 17759402 17759402 T A SNP UNC13A ENST00000428389 human ensembl 74_37 -1 known missense c.1918 p.T640S 0.999 NULL pfam_Munc13_subgr_dom-2,pfam_C2_dom,pfam_Ca-dep_secretion_activator,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_C2_dom,smart_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,prints_C2_dom 0 no_errors 0 0 0 22 0 0 10 6 37.5 150 0 0.00 114 52 31.33 IL12RB1 0 genome.wustl.edu 37 19 18180422 18180422 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 18180422 18180422 C T SNP IL12RB1 ENST00000593993 human ensembl 74_37 -1 known missense c.1123 p.G375S 0.014 NULL pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 0 no_errors 0 0 0 30 0 0 28 12 30 78 0 0.00 42 39 48.15 IL12RB1 0 genome.wustl.edu 37 19 18186568 18186568 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 18186568 18186568 C T SNP IL12RB1 ENST00000593993 human ensembl 74_37 -1 known missense c.691 p.V231I 0.072 superfamily_Fibronectin_type3 pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 0 no_errors rs140762977 C->T 0 27 0 0 9 6 40 108 0 0.00 103 38 26.95 CILP2 0 genome.wustl.edu 37 19 19654911 19654911 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 19654911 19654911 G A SNP CILP2 ENST00000291495 human ensembl 74_37 1 known silent c.1557 p.R519 0.998 superfamily_Carb-bd-like_fold pfam_Thrombospondin_1_rpt,pfam_Ig_I-set,superfamily_Thrombospondin_1_rpt,superfamily_CarboxyPept-like_regulatory,superfamily_Carb-bd-like_fold,smart_Thrombospondin_1_rpt,smart_Ig_sub,smart_Ig_sub2,pfscan_Thrombospondin_1_rpt,pfscan_Ig-like_dom 0 no_errors 0 0 0 60 0 0 29 13 30.95 128 0 0.00 94 55 36.67 ZNF257 0 genome.wustl.edu 37 19 22235335 22235335 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 22235335 22235335 T C SNP ZNF257 ENST00000596471 human ensembl 74_37 1 known rna NULL NULL 0.002 0 0 0 no_errors 0 0 0 51 0 0 26 9 25.71 95 0 0.00 78 37 31.90 ZNF536 0 genome.wustl.edu 37 19 31039047 31039047 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 31039047 31039047 G A SNP ZNF536 ENST00000355537 human ensembl 74_37 1 known missense c.2521 p.A841T 0.999 NULL pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors rs200595340 G->A 0 33 0 0 20 9 31.03 104 0 0.00 58 28 32.56 GPI 0 genome.wustl.edu 37 19 34857309 34857309 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 34857309 34857309 C T SNP GPI ENST00000415930 human ensembl 74_37 1 known missense c.299 p.T100M 0.957 pfam_G6P_Isomerase pfam_G6P_Isomerase,prints_G6P_Isomerase 0 no_errors 0 0 0 50 0 0 31 13 29.55 169 0 0.00 130 57 30.00 LGI4 0 genome.wustl.edu 37 19 35622422 35622422 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 35622422 35622422 C T SNP LGI4 ENST00000310123 human ensembl 74_37 -1 known missense c.496 p.V166I 0.136 smart_Cys-rich_flank_reg_C pfam_EPTP,pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,pfscan_EAR 0 no_errors 0 0 0 32 0 0 19 6 23.08 53 0 0.00 28 17 37.78 ZNF585B 0 genome.wustl.edu 37 19 37676361 37676361 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 37676361 37676361 C T SNP ZNF585B ENST00000532828 human ensembl 74_37 -1 known missense c.2078 p.S693N 0.003 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 64 0 0 33 12 26.67 22 0 0.00 20 13 39.39 CATSPERG 0 genome.wustl.edu 37 19 38855535 38855535 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 38855535 38855535 C T SNP CATSPERG ENST00000409235 human ensembl 74_37 1 known missense c.2480 p.T827M 0.004 NULL NULL 0 no_errors rs200588516 C->T 0 67 0 0 37 9 19.57 254 0 0.00 206 108 34.29 PLEKHG2 0 genome.wustl.edu 37 19 39913718 39913718 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 39913718 39913718 C A SNP PLEKHG2 ENST00000409794 human ensembl 74_37 1 known missense c.2024 p.P675H 0.05 NULL pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain 0 no_errors 0 0 0 52 0 0 25 14 35.9 218 0 0.00 136 89 39.56 ZNF546 0 genome.wustl.edu 37 19 40520367 40520367 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 40520367 40520367 G A SNP ZNF546 ENST00000347077 human ensembl 74_37 1 known missense c.1190 p.G397D 0 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 59 0 0 30 6 16.22 124 0 0.00 110 29 20.86 AXL 0 genome.wustl.edu 37 19 41759589 41759589 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 41759589 41759589 G T SNP AXL ENST00000301178 human ensembl 74_37 1 known missense c.2012 p.R671L 1 pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Ig_V-set,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_Ser-Thr/Tyr_kinase_cat_dom 0 no_errors 0 0 0 55 0 0 37 14 27.45 125 0 0.00 111 42 26.58 CADM4 0 genome.wustl.edu 37 19 44130991 44130991 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 44130991 44130991 C T SNP CADM4 ENST00000222374 human ensembl 74_37 -1 known silent c.444 p.P148 0.609 pfam_CD80_C2-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom pfam_Ig_I-set,pfam_Ig_V-set,pfam_CD80_C2-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,smart_Neurexin-like,pfscan_Ig-like_dom 0 no_errors 0 0 0 59 0 0 57 24 29.63 56 0 0.00 40 14 25.45 PLAUR 0 genome.wustl.edu 37 19 44160700 44160700 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 44160700 44160700 G T SNP PLAUR ENST00000340093 human ensembl 74_37 -1 known missense c.403 p.L135M 0.999 pfam_LY6_UPAR,smart_LY6_UPA_recep-like pfam_LY6_UPAR,smart_LY6_UPA_recep-like 0 no_errors 0 0 0 28 0 0 21 6 22.22 43 0 0.00 28 15 34.88 PVR 0 genome.wustl.edu 37 19 45150743 45150743 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 45150743 45150743 A G SNP PVR ENST00000425690 human ensembl 74_37 1 known missense c.328 p.M110V 0 pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom pfam_CD80_C2-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom 0 no_errors 0 0 0 27 0 0 21 4 16 98 0 0.00 79 45 36.29 CBLC 0 genome.wustl.edu 37 19 45285627 45285627 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 45285627 45285627 C T SNP CBLC ENST00000270279 human ensembl 74_37 1 known missense c.658 p.P220S 1 pfam_Adaptor_Cbl_EF_hand-like pfam_Adaptor_Cbl_SH2-like,pfam_Adaptor_Cbl_EF_hand-like,pfam_Adaptor_Cbl_N_hlx,pfam_Znf_C3HC4_RING-type,superfamily_Adaptor_Cbl_N_hlx,smart_Znf_RING,pfscan_Znf_RING 0 no_errors 0 0 0 28 0 0 11 6 35.29 113 0 0.00 116 37 24.18 CALM3 0 genome.wustl.edu 37 19 47112136 47112136 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 47112136 47112136 C T SNP CALM3 ENST00000291295 human ensembl 74_37 1 known missense c.319 p.R107C 1 pfam_EF_hand_dom,pfam_EF-hand_Ca_insen,smart_EF_hand_dom,pfscan_EF_hand_dom,prints_Recoverin pfam_EF_hand_dom,pfam_EF-hand_Ca_insen,smart_EF_hand_dom,pfscan_EF_hand_dom,prints_Recoverin 0 no_errors 0 0 0 15 0 0 15 6 28.57 77 0 0.00 80 35 30.17 SLC8A2 0 genome.wustl.edu 37 19 47969309 47969309 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 47969309 47969309 C T SNP SLC8A2 ENST00000236877 human ensembl 74_37 -1 known missense c.352 p.V118M 1 pfam_NaCa_Exmemb,tigrfam_Na_Ca_Ex pfam_Calx_beta,pfam_NaCa_Exmemb,smart_Calx_beta,prints_Na_Ca_Ex,tigrfam_Na_Ca_Ex 0 no_errors 0 0 0 16 0 0 8 4 33.33 103 0 0.00 98 46 31.94 KPTN 0 genome.wustl.edu 37 19 47984057 47984057 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 47984057 47984057 C T SNP KPTN ENST00000338134 human ensembl 74_37 -1 known missense c.559 p.V187M 1 NULL NULL 0 no_errors 0 0 0 36 0 0 20 8 28.57 166 0 0.00 117 31 20.95 PLA2G4C 0 genome.wustl.edu 37 19 48565269 48565269 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 48565269 48565269 C T SNP PLA2G4C ENST00000599111 human ensembl 74_37 -1 known missense c.1273 p.G425R 0.993 superfamily_Acyl_Trfase/lysoPLipase,smart_LysoPLipase_cat_dom,pfscan_LysoPLipase_cat_dom pfam_LysoPLipase_cat_dom,superfamily_Acyl_Trfase/lysoPLipase,smart_LysoPLipase_cat_dom,pfscan_LysoPLipase_cat_dom 0 no_errors 0 0 0 79 0 0 45 11 19.64 135 0 0.00 88 41 31.54 CCDC114 0 genome.wustl.edu 37 19 48801293 48801293 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 48801293 48801293 G A SNP CCDC114 ENST00000315396 human ensembl 74_37 -1 known missense c.1355 p.P452L 0.001 NULL NULL 0 no_errors 0 0 0 29 0 0 28 7 20 62 0 0.00 40 12 23.08 GRWD1 0 genome.wustl.edu 37 19 48956016 48956016 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 48956016 48956016 G A SNP GRWD1 ENST00000253237 human ensembl 74_37 1 known missense c.1075 p.V359I 1 pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom pfam_WD40_repeat,pfam_Histone-bd_RBBP4_N,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep 0 no_errors 0 0 0 37 0 0 21 12 36.36 67 0 0.00 53 18 25.35 PLEKHA4 0 genome.wustl.edu 37 19 49368837 49368837 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 49368837 49368837 C T SNP PLEKHA4 ENST00000263265 human ensembl 74_37 -1 known missense c.115 p.A39T 0.926 NULL pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology 0 no_errors 0 0 0 42 0 0 21 11 34.38 186 0 0.00 215 43 16.60 PPFIA3 0 genome.wustl.edu 37 19 49633814 49633814 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 49633814 49633814 G T SNP PPFIA3 ENST00000334186 human ensembl 74_37 1 known missense c.837 p.K279N 1 NULL pfam_SAM_2,pfam_SAM_type1,superfamily_SAM/pointed,smart_SAM,pfscan_SAM 0 no_errors 0 0 0 14 0 0 10 3 23.08 33 0 0.00 37 7 15.91 TRPM4 0 genome.wustl.edu 37 19 49714514 49714514 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 49714514 49714514 C T SNP TRPM4 ENST00000252826 human ensembl 74_37 1 known missense c.3628 p.P1210S 0 NULL pfam_Ion_trans_dom 0 no_errors 0 0 0 41 0 0 36 13 26.53 107 1 0.93 78 28 26.42 ALDH16A1 0 genome.wustl.edu 37 19 49971697 49971697 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 49971697 49971697 G T SNP ALDH16A1 ENST00000293350 human ensembl 74_37 1 known silent c.1998 p.V666 0.227 pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,pirsf_Aldehyde_DH pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,pirsf_Aldehyde_DH 0 no_errors 0 0 0 57 0 0 30 27 47.37 98 0 0.00 65 24 26.97 MYH14 0 genome.wustl.edu 37 19 50713829 50713829 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 50713829 50713829 G A SNP MYH14 ENST00000262269 human ensembl 74_37 1 known silent c.207 p.A69 0.993 pfam_Myosin_N,superfamily_P-loop_NTPase pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 10 0 0 8 4 33.33 43 0 0.00 38 12 23.08 MYH14 0 genome.wustl.edu 37 19 50720873 50720873 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 50720873 50720873 C T SNP MYH14 ENST00000262269 human ensembl 74_37 1 known missense c.407 p.T136M 0.997 pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 39 0 0 28 8 22.22 151 0 0.00 88 44 33.33 SIGLEC7 0 genome.wustl.edu 37 19 51650064 51650064 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 51650064 51650064 G T SNP SIGLEC7 ENST00000317643 human ensembl 74_37 1 known missense c.1081 p.A361S 0.001 NULL pfam_Ig_V-set,pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom 0 no_errors 0 0 0 43 0 0 16 14 46.67 71 1 1.39 67 30 30.93 ZNF808 0 genome.wustl.edu 37 19 53058425 53058425 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 53058425 53058425 C T SNP ZNF808 ENST00000359798 human ensembl 74_37 1 known silent c.2256 p.C752 0.007 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 140 0 0 65 20 23.53 113 0 0.00 65 25 27.78 ZNF347 0 genome.wustl.edu 37 19 53644236 53644236 + Missense_Mutation SNP A A T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A T A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 53644236 53644236 A T SNP ZNF347 ENST00000452676 human ensembl 74_37 -1 known missense c.1848 p.H616Q 0.007 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 94 0 0 41 21 33.87 57 0 0.00 41 13 24.07 NLRP12 0 genome.wustl.edu 37 19 54308674 54308674 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 54308674 54308674 G T SNP NLRP12 ENST00000324134 human ensembl 74_37 -1 known silent c.2274 p.A758 0.979 smart_Leu-rich_rpt_RNase_inh_sub-typ pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_NACHT_NTPase,pfscan_DAPIN 0 no_errors 0 0 0 27 0 0 13 7 35 150 0 0.00 126 39 23.64 MYADM 0 genome.wustl.edu 37 19 54376795 54376795 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 54376795 54376795 G A SNP MYADM ENST00000336967 human ensembl 74_37 1 known silent c.12 p.T4 0.012 NULL pfam_Marvel 0 no_errors 0 0 0 51 0 0 10 5 33.33 208 1 0.47 154 69 30.94 LENG8 0 genome.wustl.edu 37 19 54969669 54969669 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 54969669 54969669 C T SNP LENG8 ENST00000326764 human ensembl 74_37 1 known missense c.2209 p.R737C 1 pfam_SAC3/GANP/Nin1/mts3/eIF-3-p25 pfam_SAC3/GANP/Nin1/mts3/eIF-3-p25 0 no_errors 0 0 0 14 0 0 10 3 23.08 119 0 0.00 94 46 32.62 NCR1 0 genome.wustl.edu 37 19 55417910 55417910 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 55417910 55417910 G A SNP NCR1 ENST00000291890 human ensembl 74_37 1 known missense c.100 p.E34K 0.003 smart_Ig_sub smart_Ig_sub 0 no_errors rs587627160 G->A 0.9998,0.0001997 48 0 0 23 12 34.29 147 0 0.00 144 66 31.43 PTPRH 0 genome.wustl.edu 37 19 55697888 55697888 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 55697888 55697888 G T SNP PTPRH ENST00000376350 human ensembl 74_37 -1 known missense c.2587 p.L863M 1 pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_rcpt/non-rcpt,pfscan_Tyr_Pase_rcpt/non-rcpt pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt 0 no_errors 0 0 0 18 0 0 9 5 35.71 79 0 0.00 57 23 28.75 UBE2S 0 genome.wustl.edu 37 19 55912864 55912864 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 55912864 55912864 G A SNP UBE2S ENST00000264552 human ensembl 74_37 -1 known silent c.609 p.R203 0.039 NULL pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2 0 no_errors 0 0 0 109 0 0 67 29 30.21 86 0 0.00 56 30 34.88 ZNF835 0 genome.wustl.edu 37 19 57175295 57175295 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 57175295 57175295 G A SNP ZNF835 ENST00000537055 human ensembl 74_37 -1 known silent c.1272 p.G424 0.925 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 38 0 0 14 7 33.33 48 0 0.00 42 19 31.15 USP29 0 genome.wustl.edu 37 19 57641022 57641022 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 57641022 57641022 G A SNP USP29 ENST00000254181 human ensembl 74_37 1 known missense c.979 p.A327T 0.204 pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67 pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67 0 no_errors 0 0 0 14 0 0 16 4 20 249 0 0.00 176 90 33.83 ZNF419 0 genome.wustl.edu 37 19 58003604 58003604 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 58003604 58003604 A G SNP ZNF419 ENST00000518999 human ensembl 74_37 1 putative missense c.326 p.E109G 0 NULL pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 121 0 0 47 25 34.72 195 1 0.51 164 77 31.82 ZNF419 0 genome.wustl.edu 37 19 58004926 58004926 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 58004926 58004926 A G SNP ZNF419 ENST00000424930 human ensembl 74_37 1 known missense c.1004 p.Q335R 0.95 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 143 1 0.69 57 25 30.49 158 0 0.00 147 64 30.33 ZNF587 0 genome.wustl.edu 37 19 58371214 58371214 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 58371214 58371214 C T SNP ZNF587 ENST00000339656 human ensembl 74_37 1 known silent c.1434 p.S478 0.001 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 61 0 0 44 19 30.16 60 0 0.00 35 20 36.36 ZBTB45 0 genome.wustl.edu 37 19 59028858 59028858 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 59028858 59028858 C T SNP ZBTB45 ENST00000354590 human ensembl 74_37 -1 known silent c.183 p.K61 1 pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,pfscan_BTB/POZ-like pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 50 0 0 21 3 12 34 0 0.00 32 12 27.27 ZNF343 0 genome.wustl.edu 37 20 2464361 2464361 + Nonsense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 2464361 2464361 G A SNP ZNF343 ENST00000278772 human ensembl 74_37 -1 known nonsense c.1246 p.R416* 0.119 pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box 0 no_errors 0 0 0 66 0 0 50 9 15.25 67 0 0.00 63 21 25.00 CPXM1 0 genome.wustl.edu 37 20 2776648 2776648 + Missense_Mutation SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A G A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 2776648 2776648 A G SNP CPXM1 ENST00000380605 human ensembl 74_37 -1 known missense c.1402 p.Y468H 1 pfam_Peptidase_M14,smart_Peptidase_M14 pfam_Peptidase_M14,pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,superfamily_CarboxyPept-like_regulatory,smart_Coagulation_fac_5/8-C_type_dom,smart_Peptidase_M14,pfscan_Coagulation_fac_5/8-C_type_dom,prints_Peptidase_M14 0 no_errors 0 0 0 65 0 0 35 12 25.53 170 1 0.58 137 48 25.95 LZTS3 0 genome.wustl.edu 37 20 3145236 3145236 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 3145236 3145236 C T SNP LZTS3 ENST00000329152 human ensembl 74_37 -1 known missense c.1886 p.R629H 1 NULL NULL 0 no_errors 0 0 0 11 0 0 13 8 38.1 37 0 0.00 43 16 27.12 LRRN4 0 genome.wustl.edu 37 20 6032917 6032917 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 6032917 6032917 G T SNP LRRN4 ENST00000378858 human ensembl 74_37 -1 known missense c.529 p.L177I 0.997 NULL pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Fibronectin_type3,pfscan_Fibronectin_type3 0 no_errors 0 0 0 10 0 0 0 2 100 5 0 0.00 6 3 33.33 SSTR4 0 genome.wustl.edu 37 20 23016417 23016417 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 23016417 23016417 C T SNP SSTR4 ENST00000255008 human ensembl 74_37 1 known silent c.297 p.S99 0.906 pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_Neuropept_B/W_rcpt pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfam_7TM_GPCR_serpentine_rcpt_Srw,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Somatstn_rcpt_4,prints_GPCR_Rhodpsn,prints_Somatstn_rcpt,prints_Opioid_rcpt,prints_Neuropept_B/W_rcpt,prints_NPY_rcpt,prints_Somatstn_rcpt_1 0 no_errors 0 0 0 29 0 0 7 5 41.67 25 0 0.00 20 5 20.00 KIF3B 0 genome.wustl.edu 37 20 30915423 30915423 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 30915423 30915423 G A SNP KIF3B ENST00000375712 human ensembl 74_37 1 known missense c.1927 p.A643T 1 NULL pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom 0 no_errors 0 0 0 19 0 0 16 3 15.79 254 0 0.00 141 74 34.42 GGT7 0 genome.wustl.edu 37 20 33438722 33438722 + Splice_Site SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 33438722 33438722 T C SNP GGT7 ENST00000469018 human ensembl 74_37 -1 known splice_site c.NULL NULL 0 0 0 0 no_errors 0 0 0 50 0 0 28 8 22.22 266 0 0.00 235 78 24.92 GDF5 0 genome.wustl.edu 37 20 34022399 34022399 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 34022399 34022399 G A SNP GDF5 ENST00000374369 human ensembl 74_37 -1 known missense c.814 p.R272W 1 pfam_TGF-b_N pfam_TGF-b_C,pfam_TGF-b_N,smart_TGF-b_C 0 no_errors 0 0 0 26 0 0 15 12 44.44 10 0 0.00 6 8 57.14 TTI1 0 genome.wustl.edu 37 20 36625224 36625224 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 36625224 36625224 C T SNP TTI1 ENST00000373447 human ensembl 74_37 -1 known silent c.2925 p.S975 0.993 superfamily_ARM-type_fold,pirsf_UCP005250 superfamily_ARM-type_fold,pirsf_UCP005250 0 no_errors 0 0 0 44 0 0 23 6 20.69 105 0 0.00 84 27 24.32 TOP1 0 genome.wustl.edu 37 20 39690075 39690075 + Silent SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 39690075 39690075 C A SNP TOP1 ENST00000361337 human ensembl 74_37 1 known silent c.100 p.R34 1 NULL pfam_TopoI_DNA-bd_euk,pfam_TopoI_cat_euk,superfamily_TopoI_DNA-bd_euk,superfamily_DNA_brk_join_enz,smart_TopoI_euk,prints_TopoI 0 no_errors 0 0 0 78 0 0 48 5 9.43 181 0 0.00 181 12 6.22 CHD6 0 genome.wustl.edu 37 20 40033425 40033425 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 40033425 40033425 G A SNP CHD6 ENST00000373233 human ensembl 74_37 -1 known silent c.7956 p.S2652 1 NULL pfam_SNF2_N,pfam_Chromo_domain,pfam_Helicase_C,pfam_Helicase/UvrB_dom,pfam_BRK_domain,pfam_DNA/RNA_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,smart_BRK_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow 0 no_errors 0 0 0 33 0 0 19 5 20.83 92 0 0.00 69 32 31.07 TSHZ2 0 genome.wustl.edu 37 20 51871248 51871248 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 51871248 51871248 G T SNP TSHZ2 ENST00000371497 human ensembl 74_37 1 known missense c.1251 p.K417N 1 NULL superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Znf_C2H2 0 no_errors 0 0 0 40 0 0 14 12 46.15 149 0 0.00 113 47 29.38 MIR1257 0 genome.wustl.edu 37 20 60528652 60528652 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 60528652 60528652 C T SNP MIR1257 ENST00000408490 human ensembl 74_37 -1 known rna NULL NULL 0.022 0 0 0 no_errors 0 0 0 33 0 0 24 6 20 51 0 0.00 37 8 17.39 LAMA5 0 genome.wustl.edu 37 20 60921237 60921237 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 60921237 60921237 G A SNP LAMA5 ENST00000252999 human ensembl 74_37 -1 known silent c.1317 p.T439 0.996 pfam_EGF_laminin,smart_EG-like_dom,smart_EGF_laminin,pfscan_EGF_laminin pfam_EGF_laminin,pfam_Laminin_I,pfam_Laminin_G,pfam_Laminin_N,pfam_Laminin_II,pfam_Laminin_B_type_IV,superfamily_ConA-like_lec_gl_sf,superfamily_Galactose-bd-like,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,smart_Laminin_B_subgr,smart_Laminin_G,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_G,pfscan_Laminin_N,pfscan_TNFR/NGFR_Cys_rich_reg 0 no_errors 0 0 0 26 0 0 29 13 30.95 73 0 0.00 55 20 26.67 JAM2 0 genome.wustl.edu 37 21 27066109 27066109 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 27066109 27066109 C T SNP JAM2 ENST00000312957 human ensembl 74_37 1 known missense c.283 p.R95W 0.962 pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom 0 no_errors rs372458284 C->T 0 102 0 0 60 27 31.03 200 0 0.00 201 68 25.28 SON 0 genome.wustl.edu 37 21 34926132 34926132 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 34926132 34926132 T C SNP SON ENST00000356577 human ensembl 74_37 1 known missense c.4595 p.I1532T 0 NULL pfam_G_patch_dom,superfamily_WD40_repeat_dom,smart_G_patch_dom,pfscan_G_patch_dom,pfscan_dsRNA-bd_dom 0 no_errors 0 0 0 68 0 0 33 17 34 212 0 0.00 159 77 32.49 MORC3 0 genome.wustl.edu 37 21 37732258 37732258 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 37732258 37732258 G A SNP MORC3 ENST00000400485 human ensembl 74_37 1 known missense c.1214 p.R405H 0.992 pfscan_Znf_CW pfam_Znf_CW,pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,pfscan_Znf_CW 0 no_errors 0 0 0 85 0 0 33 20 37.74 239 1 0.41 182 79 30.27 DSCR3 0 genome.wustl.edu 37 21 38600536 38600536 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 38600536 38600536 C T SNP DSCR3 ENST00000309117 human ensembl 74_37 -1 known missense c.646 p.V216M 1 pfam_VPS26 pfam_VPS26,pfam_Arrestin-like_N,superfamily_Ig_E-set 0 no_errors 0 0 0 23 0 0 11 4 26.67 31 0 0.00 32 11 25.58 DSCAM 0 genome.wustl.edu 37 21 41446994 41446994 + Silent SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 41446994 41446994 G T SNP DSCAM ENST00000400454 human ensembl 74_37 -1 known silent c.4858 p.R1620 0.998 NULL pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub2,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom 0 no_errors rs201077680 G->T 0.9996,0.0003994 57 0 0 22 17 43.59 56 0 0.00 47 14 22.95 ABCG1 0 genome.wustl.edu 37 21 43710176 43710176 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 43710176 43710176 G A SNP ABCG1 ENST00000398437 human ensembl 74_37 1 known missense c.1715 p.R572H 1 pfam_ABC_2_trans,tigrfam_Pigment_permease pfam_ABC_2_trans,pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,tigrfam_Pigment_permease 0 no_errors 0 0 0 70 1 1.41 22 10 31.25 142 1 0.70 111 26 18.98 PDE9A 0 genome.wustl.edu 37 21 44163955 44163955 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 44163955 44163955 C T SNP PDE9A ENST00000291539 human ensembl 74_37 1 known missense c.638 p.A213V 0.998 NULL pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom,prints_PDEase 0 no_errors 0 0 0 19 0 0 15 5 25 69 0 0.00 58 23 28.05 MCM3AP 0 genome.wustl.edu 37 21 47697536 47697536 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 21 47697536 47697536 C T SNP MCM3AP ENST00000291688 human ensembl 74_37 -1 known missense c.1763 p.C588Y 0.018 NULL pfam_SAC3/GANP/Nin1/mts3/eIF-3-p25 0 no_errors 0 0 0 41 0 0 26 13 33.33 60 0 0.00 56 18 24.32 GNAZ 0 genome.wustl.edu 37 22 23437978 23437978 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 23437978 23437978 C T SNP GNAZ ENST00000248996 human ensembl 74_37 1 known silent c.96 p.R32 0.004 pfam_Gprotein_alpha_su,superfamily_P-loop_NTPase,smart_Gprotein_alpha_su pfam_Gprotein_alpha_su,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,superfamily_GproteinA_insert,smart_Gprotein_alpha_su,prints_Gprotein_alpha_su,prints_Gprotein_alpha_I 0 no_errors 0 0 0 33 0 0 28 10 26.32 25 0 0.00 31 15 32.61 MORC2 0 genome.wustl.edu 37 22 31328601 31328601 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 31328601 31328601 C T SNP MORC2 ENST00000397641 human ensembl 74_37 -1 known missense c.2678 p.R893H 0.363 NULL pfam_Znf_CW,pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,superfamily_Carb-bd_dom,pfscan_Znf_CW 0 no_errors rs202243108 C->T 0.9998,0.0001997 58 0 0 24 10 28.57 123 0 0.00 105 49 31.82 TIMP3 0 genome.wustl.edu 37 22 33253242 33253242 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 33253242 33253242 C T SNP TIMP3 ENST00000266085 human ensembl 74_37 1 known nonsense c.211 p.R71* 1 pfam_Prot_inh_TIMP,superfamily_TIMP-like_OB-fold,smart_Prot_inh_TIMP,pfscan_Netrin_domain pfam_Prot_inh_TIMP,superfamily_TIMP-like_OB-fold,smart_Prot_inh_TIMP,pfscan_Netrin_domain 0 no_errors 0 0 0 64 0 0 27 10 27.03 220 0 0.00 181 72 28.35 MPST 0 genome.wustl.edu 37 22 37420809 37420809 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 37420809 37420809 G A SNP MPST ENST00000397129 human ensembl 74_37 1 known missense c.613 p.A205T 0.025 pfam_Rhodanese-like_dom,superfamily_Rhodanese-like_dom,smart_Rhodanese-like_dom,pfscan_Rhodanese-like_dom pfam_Rhodanese-like_dom,superfamily_Rhodanese-like_dom,smart_Rhodanese-like_dom,pfscan_Rhodanese-like_dom 0 no_errors 0 0 0 51 0 0 38 7 15.56 89 0 0.00 45 21 31.34 GGA1 0 genome.wustl.edu 37 22 38025516 38025516 + Nonsense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G T G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 38025516 38025516 G T SNP GGA1 ENST00000343632 human ensembl 74_37 1 known nonsense c.1141 p.G381* 0.921 NULL pfam_VHS,pfam_GAT,pfam_Clathrin_a/b/g-adaptin_app_Ig,superfamily_Coatomer/clathrin_app_Ig-like,superfamily_ENTH_VHS,smart_VHS_subgr,smart_Clathrin_a/b/g-adaptin_app_Ig,pfscan_Clathrin_g-adaptin_app,pfscan_GAT,pfscan_VHS 0 no_errors 0 0 0 35 0 0 25 4 13.79 188 0 0.00 147 58 28.16 TRIOBP 0 genome.wustl.edu 37 22 38121513 38121513 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 38121513 38121513 G A SNP TRIOBP ENST00000406386 human ensembl 74_37 1 known missense c.2950 p.G984S 0.161 NULL pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology 0 no_errors 0 0 0 23 0 0 14 9 39.13 186 0 0.00 131 27 16.98 ENTHD1 0 genome.wustl.edu 37 22 40257914 40257914 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 40257914 40257914 G A SNP ENTHD1 ENST00000325157 human ensembl 74_37 -1 known missense c.448 p.R150C 0.759 NULL pfam_Epsin_dom_N,pfam_VHS,superfamily_ENTH_VHS,smart_Epsin-like_N,pfscan_Epsin-like_N 0 no_errors 0 0 0 89 0 0 70 22 23.91 208 0 0.00 187 78 29.32 SLC25A17 0 genome.wustl.edu 37 22 41188562 41188562 + Missense_Mutation SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T C T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 41188562 41188562 T C SNP SLC25A17 ENST00000435456 human ensembl 74_37 -1 known missense c.301 p.T101A 1 pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_carrier 0 no_errors rs113893475 T->C 0 120 0 0 55 22 28.57 296 0 0.00 235 115 32.76 EP300 0 genome.wustl.edu 37 22 41564729 41564729 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 41564729 41564729 G A SNP EP300 ENST00000263253 human ensembl 74_37 1 known missense c.4030 p.V1344M 1 pfam_Histone_H3-K56_AcTrfase_RTT109 pfam_Histone_H3-K56_AcTrfase_RTT109,pfam_Nuc_rcpt_coact_CREBbp,pfam_KIX_dom,pfam_DUF902_CREBbp,pfam_Znf_TAZ,pfam_Bromodomain,pfam_Znf_ZZ,superfamily_Bromodomain,superfamily_Znf_TAZ,superfamily_KIX_dom,superfamily_Nuc_rcpt_coact,superfamily_Znf_FYVE_PHD,smart_Znf_TAZ,smart_Bromodomain,smart_Znf_ZZ,pfscan_KIX_dom,pfscan_Znf_TAZ,pfscan_Znf_ZZ,pfscan_Bromodomain,prints_Bromodomain 0 no_errors 0 0 0 92 0 0 46 15 24.19 289 2 0.68 213 86 28.67 SEPT3 0 genome.wustl.edu 37 22 42383764 42383764 + Splice_Site SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G A G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 42383764 42383764 G A SNP SEPT3 ENST00000396426 human ensembl 74_37 1 known splice_site c.551+1 e5+1 1 0 0 0 no_errors rs574717482 G->A 0.9998,0.0001997 44 0 0 37 6 13.95 202 0 0.00 182 81 30.57 PARVB 0 genome.wustl.edu 37 22 44532343 44532343 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 44532343 44532343 C T SNP PARVB ENST00000406477 human ensembl 74_37 1 known missense c.736 p.R246W 1 superfamily_CH-domain pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain 0 no_errors 0 0 0 40 0 0 16 3 15.79 155 0 0.00 135 57 29.69 CELSR1 0 genome.wustl.edu 37 22 46835085 46835085 + Splice_Site SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 46835085 46835085 C T SNP CELSR1 ENST00000262738 human ensembl 74_37 -1 known splice_site c.4406+1 e3+1 1 0 0 0 no_errors 0 0 0 73 0 0 39 22 36.07 87 0 0.00 68 27 28.42 BRD1 0 genome.wustl.edu 37 22 50191729 50191729 + Missense_Mutation SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C A C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 50191729 50191729 C A SNP BRD1 ENST00000216267 human ensembl 74_37 -1 known missense c.1822 p.D608Y 1 pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain pfam_Enhancer_polycomb-like_N,pfam_Bromodomain,pfam_PWWP_dom,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_Bromodomain,smart_PWWP_dom,prints_Bromodomain,pfscan_PWWP_dom,pfscan_Znf_PHD-finger,pfscan_Bromodomain 0 no_errors 0 0 0 104 0 0 32 12 27.27 313 0 0.00 272 81 22.95 SHANK3 0 genome.wustl.edu 37 22 51159900 51159900 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C T C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 22 51159900 51159900 C T SNP SHANK3 ENST00000262795 human ensembl 74_37 1 known silent c.3687 p.H1229 0.977 NULL pfam_SAM_type1,pfam_Ankyrin_rpt,pfam_SAM_2,pfam_SH3_2,pfam_PDZ,superfamily_Ankyrin_rpt-contain_dom,superfamily_PDZ,superfamily_SAM/pointed,superfamily_SH3_domain,smart_Ankyrin_rpt,smart_SH3_domain,smart_PDZ,smart_SAM,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_PDZ,pfscan_SAM,pfscan_SH3_domain 0 no_errors 0 0 0 35 0 0 17 4 19.05 23 0 0.00 26 9 25.71 ARSH 0 genome.wustl.edu 37 X 2936599 2936600 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 2936599 2936600 0 T INS ARSH ENST00000381130 human ensembl 74_37 1 known frame_shift_ins c.789_790 p.S265fs 0.125:0.107 pfam_Sulfatase,superfamily_Alkaline_phosphatase_core pfam_Sulfatase,pfam_Phosphodiest/P_Trfase,superfamily_Alkaline_phosphatase_core 0 no_errors rs368634386 C->CT 0 155 0 0 61 22 26.51 266 0 0.00 255 96 27.35 OFD1 0 genome.wustl.edu 37 X 13780494 13780494 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 13780494 13780494 A 0 DEL OFD1 ENST00000340096 human ensembl 74_37 1 known frame_shift_del c.2419 p.S808fs 0.001 NULL superfamily_Lipoprotein_6,smart_LisH_dimerisation,pfscan_LisH_dimerisation 0 no_errors 0 0 0 260 0 0 135 53 28.19 269 0 0.00 163 77 32.08 SAT1 0 genome.wustl.edu 37 X 23804224 23804225 + RNA INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 23804224 23804225 0 A INS SAT1 ENST00000462639 human ensembl 74_37 1 known rna NULL NULL 0.043:0.385 0 0 0 no_errors 0 0 0 103 0 0 72 18 20 289 0 0.00 261 91 25.85 ATRX 0 genome.wustl.edu 37 X 76763771 76763772 + RNA INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 76763771 76763772 0 A INS ATRX ENST00000480283 human ensembl 74_37 -1 known rna NULL NULL 1.000:1.000 0 0 0 no_errors 0 0 0 83 0 0 31 17 35.42 285 0 0.00 227 93 29.06 PGK1 0 genome.wustl.edu 37 X 77381539 77381539 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 77381539 77381539 T 0 DEL PGK1 ENST00000476531 human ensembl 74_37 1 known rna NULL NULL 0.997 0 0 0 no_errors 0 0 0 37 0 0 25 8 24.24 90 0 0.00 63 29 31.52 ZNF711 0 genome.wustl.edu 37 X 84526621 84526621 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 84526621 84526621 A 0 DEL ZNF711 ENST00000395402 human ensembl 74_37 1 known frame_shift_del c.2097 p.K701fs 0.506 smart_Znf_C2H2-like,pfscan_Znf_C2H2 pfam_Transcrp_activ_Zfx/Zfy-dom,pfam_Znf_C2H2,pfam_Znf_C2H2_jaz,smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 94 0 0 45 24 34.78 220 0 0.00 161 76 32.07 HNRNPH2 0 genome.wustl.edu 37 X 100668112 100668112 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 100668112 100668112 T 0 DEL HNRNPH2 ENST00000316594 human ensembl 74_37 1 known frame_shift_del c.1136 p.L381fs 1 NULL pfam_RRM_dom,pfam_Znf_CHHC,smart_RRM_dom,pfscan_RRM_dom 0 no_errors 0 0 0 30 0 0 19 8 29.63 139 0 0.00 111 52 31.90 FAM122B 0 genome.wustl.edu 37 X 133905128 133905128 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 133905128 133905128 A 0 DEL FAM122B ENST00000478384 human ensembl 74_37 -1 known rna NULL NULL 0.004 0 0 0 no_errors 0 0 0 81 0 0 55 22 28.57 211 1 0.47 204 97 32.23 RBMX 0 genome.wustl.edu 37 X 135961586 135961589 + Frame_Shift_Del DEL TGTT TGTT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TGTT TGTT TGTT - TGTT TGTT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 135961586 135961589 TGTT 0 DEL RBMX ENST00000320676 human ensembl 74_37 -1 known frame_shift_del c.1 p.M1fs 1 NULL pfam_RRM_dom,pfam_RBM1CTR,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom 0 no_errors 0 0 0 30 0 0 17 4 19.05 95 1 1.04 89 39 30.47 FGF13 0 genome.wustl.edu 37 X 137939823 137939823 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 137939823 137939823 G 0 DEL FGF13 ENST00000370603 human ensembl 74_37 -1 known frame_shift_del c.68 p.P23fs 1 NULL pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam,prints_IL-1_fam/FGF_fam,prints_Fibroblast_GF_fam 0 no_errors 0 0 0 31 0 0 22 9 29.03 200 1 0.50 161 80 33.20 PRRG3 0 genome.wustl.edu 37 X 150869296 150869297 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 150869296 150869297 0 G INS PRRG3 ENST00000370353 human ensembl 74_37 1 known frame_shift_ins c.487_488 p.R166fs 0.000:0.000 NULL pfam_GLA_domain,superfamily_GLA_domain,smart_GLA_domain,pfscan_GLA_domain,prints_GLA_domain 0 no_errors 0 0 0 21 0 0 18 4 18.18 53 0 0.00 35 18 33.96 ZNF185 0 genome.wustl.edu 37 X 152087569 152087570 + In_Frame_Ins INS - - GAG TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - GAG - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 152087569 152087570 0 GAG INS ZNF185 ENST00000370270 human ensembl 74_37 1 known in_frame_ins c.474_475 p.162in_frame_insE 0.000:0.026 NULL smart_Znf_LIM,pfscan_Znf_LIM 0 no_errors 0 0 0 50 0 0 23 17 42.5 76 0 0.00 105 21 16.67 MEGF6 0 genome.wustl.edu 37 1 3410403 3410404 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 3410403 3410404 0 C INS MEGF6 ENST00000356575 human ensembl 74_37 -1 known frame_shift_ins c.4319_4318 p.A1440fs 0.000:0.000 smart_EG-like_dom,smart_EGF_laminin pfam_EGF_laminin,pfam_EGF-like_Ca-bd_dom,superfamily_Growth_fac_rcpt_N_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_EGF_laminin,pfscan_EG-like_dom,pfscan_EMI_domain 0 no_errors 0 0 0 54 0 0 36 10 21.74 95 0 0.00 73 30 29.13 CCDC27 0 genome.wustl.edu 37 1 3672108 3672108 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 3672108 3672108 G 0 DEL CCDC27 ENST00000294600 human ensembl 74_37 1 known frame_shift_del c.530 p.G178fs 0 NULL superfamily_Prefoldin 0 no_errors 0 0 0 23 0 0 14 5 26.32 109 0 0.00 70 31 30.69 RPL22 0 genome.wustl.edu 37 1 6257785 6257785 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 6257785 6257785 T 0 DEL RPL22 ENST00000234875 human ensembl 74_37 -1 known frame_shift_del c.44 p.K15fs 1 pfam_Ribosomal_L22e pfam_Ribosomal_L22e 0 no_errors 0 0 0 54 1 1.82 17 21 55.26 92 1 1.08 37 47 55.95 PLEKHG5 0 genome.wustl.edu 37 1 6536002 6536003 + Frame_Shift_Del DEL CA CA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 CA CA CA - CA CA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 6536002 6536003 CA 0 DEL PLEKHG5 ENST00000537245 human ensembl 74_37 -1 known frame_shift_del c.375_374 p.V125fs 0.069:0.003 NULL pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain 0 no_errors 0 0 0 49 0 0 33 7 17.5 93 0 0.00 75 23 23.47 C1orf127 0 genome.wustl.edu 37 1 11007833 11007833 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 11007833 11007833 C 0 DEL C1orf127 ENST00000377004 human ensembl 74_37 -1 known frame_shift_del c.2359 p.A787fs 0 superfamily_DNA-bd_dom_put superfamily_DNA-bd_dom_put 0 no_errors 0 0 0 20 0 0 6 7 53.85 70 0 0.00 37 18 32.73 SPEN 0 genome.wustl.edu 37 1 16256949 16256950 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 16256949 16256950 0 T INS SPEN ENST00000375759 human ensembl 74_37 1 known frame_shift_ins c.4214_4215 p.L1407fs 1.000:1.000 NULL pfam_RRM_dom,pfam_SPOC_C,superfamily_SPOC_like_C_dom,smart_RRM_dom,pfscan_SPOC_met,pfscan_RRM_dom 0 no_errors 0 0 0 31 0 0 20 6 23.08 210 0 0.00 178 60 25.21 MUL1 0 genome.wustl.edu 37 1 20827665 20827665 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 20827665 20827665 C 0 DEL MUL1 ENST00000264198 human ensembl 74_37 -1 known frame_shift_del c.577 p.A193fs 1 pfam_MULAN pfam_MULAN,pfscan_Znf_RING 0 no_errors 0 0 0 32 0 0 18 9 33.33 215 0 0.00 162 47 22.49 HP1BP3 0 genome.wustl.edu 37 1 21106338 21106338 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 21106338 21106338 T 0 DEL HP1BP3 ENST00000312239 human ensembl 74_37 -1 known frame_shift_del c.163 p.S55fs 1 NULL pfam_Histone_H1/H5_H15,smart_Histone_H1/H5_H15 0 no_errors 0 0 0 117 0 0 96 36 27.27 286 0 0.00 285 118 29.28 EIF4G3 0 genome.wustl.edu 37 1 21306905 21306905 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 21306905 21306905 G 0 DEL EIF4G3 ENST00000374937 human ensembl 74_37 -1 known frame_shift_del c.268 p.Q90fs 1 NULL pfam_MIF4G-like_typ-3,pfam_Initiation_fac_eIF4g_MI,pfam_W2_domain,superfamily_ARM-type_fold,smart_MIF4G-like_typ-3,smart_Initiation_fac_eIF4g_MI,smart_W2_domain 0 no_errors 0 0 0 160 0 0 99 30 23.26 201 0 0.00 164 47 22.27 ALPL 0 genome.wustl.edu 37 1 21904120 21904120 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 21904120 21904120 C 0 DEL ALPL ENST00000374832 human ensembl 74_37 1 known frame_shift_del c.1554 p.L520fs 0 NULL pfam_Alkaline_phosphatase,superfamily_Alkaline_phosphatase_core,smart_Alkaline_phosphatase,prints_Alkaline_phosphatase 0 no_errors 0 0 0 38 0 0 18 8 30.77 36 0 0.00 28 10 26.32 MAP7D1 0 genome.wustl.edu 37 1 36642311 36642313 + In_Frame_Del DEL AGA AGA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AGA AGA AGA - AGA AGA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 36642311 36642313 AGA 0 DEL MAP7D1 ENST00000373151 human ensembl 74_37 1 known in_frame_del c.1247_1249 p.K418in_frame_del 1.000:0.996:1.000 NULL pfam_MAP7 0 no_errors 0 0 0 52 0 0 37 7 15.91 123 0 0.00 84 23 21.50 PPAP2B 0 genome.wustl.edu 37 1 56962089 56962089 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 56962089 56962089 T 0 DEL PPAP2B ENST00000472957 human ensembl 74_37 -1 known rna NULL NULL 0.869 0 0 0 no_errors 0 0 0 23 1 4.17 11 4 26.67 108 2 1.82 118 20 14.49 FUBP1 0 genome.wustl.edu 37 1 78413956 78413956 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 78413956 78413956 A 0 DEL FUBP1 ENST00000489495 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 48 0 0 32 8 20 255 0 0.00 247 102 29.23 PRKACB 0 genome.wustl.edu 37 1 84644763 84644763 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 84644763 84644763 T 0 DEL PRKACB ENST00000467507 human ensembl 74_37 1 known rna NULL NULL 0.001 0 0 0 no_errors 0 0 0 254 0 0 124 55 30.73 166 0 0.00 97 49 33.56 CDC14A 0 genome.wustl.edu 37 1 100908567 100908567 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 100908567 100908567 T 0 DEL CDC14A ENST00000469387 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 89 0 0 54 21 28 243 1 0.41 235 79 25.16 CEPT1 0 genome.wustl.edu 37 1 111703836 111703836 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 111703836 111703836 T 0 DEL CEPT1 ENST00000357172 human ensembl 74_37 1 known frame_shift_del c.547 p.C185fs 1 pfam_CDP-OH_P_trans,pirsf_CHOPT pfam_CDP-OH_P_trans,pirsf_CHOPT 0 no_errors 0 0 0 88 0 0 48 21 30.43 191 0 0.00 172 64 27.12 ZNF687 0 genome.wustl.edu 37 1 151261161 151261162 + Frame_Shift_Del DEL TC TC - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TC TC TC - TC TC Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 151261161 151261162 TC 0 DEL ZNF687 ENST00000324048 human ensembl 74_37 1 known frame_shift_del c.2273_2274 p.R760fs 1.000:1.000 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 62 0 0 47 17 26.56 139 0 0.00 189 30 13.70 KPRP 0 genome.wustl.edu 37 1 152732859 152732859 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 152732859 152732859 C 0 DEL KPRP ENST00000368773 human ensembl 74_37 1 known frame_shift_del c.795 p.R267fs 0 NULL NULL 0 no_errors 0 0 0 49 0 0 64 20 23.81 106 0 0.00 137 19 12.18 TPM3 0 genome.wustl.edu 37 1 154144891 154144892 + RNA INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 154144891 154144892 0 T INS TPM3 ENST00000469717 human ensembl 74_37 -1 known rna NULL NULL 0.013:0.015 0 0 0 no_errors rs200258420 A->AT 0 31 0 0 18 6 25 70 1 1.41 112 21 15.79 UBAP2L 0 genome.wustl.edu 37 1 154227293 154227294 + RNA DEL TT TT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TT TT TT - TT TT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 154227293 154227294 TT 0 DEL UBAP2L ENST00000495676 human ensembl 74_37 1 known rna NULL NULL 0.026:0.101 0 0 0 no_errors 0 0 0 27 0 0 31 11 26.19 54 0 0.00 71 53 42.74 SHC1 0 genome.wustl.edu 37 1 154938890 154938890 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 154938890 154938890 C 0 DEL SHC1 ENST00000368445 human ensembl 74_37 -1 known frame_shift_del c.1087 p.V363fs 0.93 NULL pfam_PTB/PI_dom,pfam_SH2,smart_PTB/PI_dom,smart_SH2,pfscan_PTB/PI_dom,pfscan_SH2,prints_PID_Shc-like,prints_SH2 0 no_errors 0 0 0 85 1 1.16 63 18 22.22 80 0 0.00 115 37 24.34 THBS3 0 genome.wustl.edu 37 1 155177643 155177643 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 155177643 155177643 C 0 DEL THBS3 ENST00000368378 human ensembl 74_37 -1 known frame_shift_del c.25 p.A9fs 1 NULL pfam_Thrombospondin_C,pfam_Thbs/COMP_coiled-coil,pfam_Thrombospondin_3-like_rpt,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom 0 no_errors 0 0 0 56 0 0 30 5 14.29 106 0 0.00 107 26 19.55 CLK2 0 genome.wustl.edu 37 1 155232988 155232988 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 155232988 155232988 G 0 DEL CLK2 ENST00000476983 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 56 0 0 31 6 16.22 114 0 0.00 101 31 23.48 YY1AP1 0 genome.wustl.edu 37 1 155658220 155658221 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 155658220 155658221 0 C INS YY1AP1 ENST00000368339 human ensembl 74_37 -1 known frame_shift_ins c.36_35 p.R13fs 0.990:0.989 NULL NULL 0 no_errors 0 0 0 62 0 0 57 15 20.83 110 0 0.00 111 42 27.45 ISG20L2 0 genome.wustl.edu 37 1 156694023 156694023 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 156694023 156694023 G 0 DEL ISG20L2 ENST00000313146 human ensembl 74_37 -1 known frame_shift_del c.865 p.L289fs 0.997 pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease 0 no_errors 0 0 0 29 0 0 27 6 18.18 85 0 0.00 100 32 24.24 ATP1A2 0 genome.wustl.edu 37 1 160093111 160093111 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 160093111 160093111 G 0 DEL ATP1A2 ENST00000361216 human ensembl 74_37 1 known frame_shift_del c.286 p.F98fs 1 pfam_ATPase_P-typ_cation-transptr_N,smart_ATPase_P-typ_cation-transptr_N,tigrfam_ATPase_P-typ_Na/K_IIC pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_cation-transptr_C,pfam_HAD-like_dom,pfam_ATPase_P-typ_cation-transptr_N,superfamily_ATPase_P-typ_cyto_domN,superfamily_HAD-like_dom,smart_ATPase_P-typ_cation-transptr_N,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Na/K_IIC,tigrfam_Cation_transp_P_typ_ATPase 0 no_errors 0 0 0 64 0 0 56 19 25.33 136 0 0.00 158 58 26.85 ENSG00000228863 0 genome.wustl.edu 37 1 160643186 160643187 + RNA INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 160643186 160643187 0 T INS ENSG00000228863 ENST00000443928 human ensembl 74_37 1 known rna NULL NULL 0.004:0.000 0 0 0 no_errors 0 0 0 12 0 0 11 7 38.89 174 0 0.00 209 54 20.53 NUF2 0 genome.wustl.edu 37 1 163313649 163313649 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 163313649 163313649 A 0 DEL NUF2 ENST00000271452 human ensembl 74_37 1 known frame_shift_del c.796 p.N267fs 0.906 NULL pfam_Kinetochore_Nuf2 0 no_errors 0 0 0 332 0 0 279 73 20.74 169 0 0.00 234 57 19.59 GPR161 0 genome.wustl.edu 37 1 168054869 168054869 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 168054869 168054869 C 0 DEL GPR161 ENST00000537209 human ensembl 74_37 -1 known frame_shift_del c.1550 p.G517fs 0 NULL pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 44 0 0 38 9 19.15 66 0 0.00 112 33 22.76 ENSG00000232113 0 genome.wustl.edu 37 1 173604977 173604977 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 173604977 173604977 A 0 DEL ENSG00000232113 ENST00000417563 human ensembl 74_37 1 known rna NULL NULL 0.989 0 0 0 no_errors 0 0 0 51 0 0 21 13 38.24 276 2 0.72 339 108 24.16 CENPL 0 genome.wustl.edu 37 1 173776460 173776461 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 173776460 173776461 0 A INS CENPL ENST00000356198 human ensembl 74_37 -1 known frame_shift_ins c.365_364 p.S122fs 1.000:1.000 NULL NULL 0 no_errors 0 0 0 178 0 0 154 62 28.7 307 0 0.00 409 76 15.67 RGL1 0 genome.wustl.edu 37 1 183857685 183857685 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 183857685 183857685 A 0 DEL RGL1 ENST00000304685 human ensembl 74_37 1 known frame_shift_del c.1134 p.K380fs 0.998 pfam_RasGRF_CDC25,superfamily_Ras_GEF_dom,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25 pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,pfam_Ras-assoc,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,smart_Ras-assoc,pfscan_Ras-assoc,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N 0 no_errors 0 0 0 113 0 0 69 12 14.81 240 0 0.00 321 72 18.32 DNAH14 0 genome.wustl.edu 37 1 225211543 225211543 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 225211543 225211543 A 0 DEL DNAH14 ENST00000430092 human ensembl 74_37 1 known frame_shift_del c.1334 p.K447fs 0.965 NULL pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,superfamily_P-loop_NTPase,superfamily_Tautomerase/MIF_sf,smart_AAA+_ATPase 0 no_errors 0 0 0 66 0 0 49 13 20.97 184 1 0.54 208 57 21.51 ARID4B 0 genome.wustl.edu 37 1 235345419 235345419 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 235345419 235345419 T 0 DEL ARID4B ENST00000264183 human ensembl 74_37 -1 known frame_shift_del c.2815 p.T939fs 1 NULL pfam_RBB1NT,pfam_ARID/BRIGHT_DNA-bd,pfam_Tudor-knot,superfamily_ARID/BRIGHT_DNA-bd,superfamily_Chromodomain-like,smart_Tudor,smart_ARID/BRIGHT_DNA-bd,pfscan_ARID/BRIGHT_DNA-bd 0 no_errors 0 0 0 65 0 0 51 10 16.39 231 1 0.43 262 72 21.56 HEATR1 0 genome.wustl.edu 37 1 236744567 236744569 + In_Frame_Del DEL GAG GAG - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 GAG GAG GAG - GAG GAG Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 236744567 236744569 GAG 0 DEL HEATR1 ENST00000366582 human ensembl 74_37 -1 known in_frame_del c.2710_2708 p.SQKTQ903in_frame_del* 0.998:0.920:0.863 superfamily_ARM-type_fold pfam_BP28_C_dom,pfam_U3snoRNP10,superfamily_ARM-type_fold 0 no_errors 0 0 0 46 0 0 45 8 15.09 146 0 0.00 213 46 17.76 CHRM3 0 genome.wustl.edu 37 1 240072444 240072444 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 240072444 240072444 A 0 DEL CHRM3 ENST00000255380 human ensembl 74_37 1 known frame_shift_del c.1693 p.K567fs 1 NULL pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Musac_Ach_M3_rcpt,prints_Musac_Ach_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 28 0 0 33 7 17.5 93 1 1.06 115 22 16.06 KIF26B 0 genome.wustl.edu 37 1 245849693 245849694 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 245849693 245849694 0 A INS KIF26B ENST00000407071 human ensembl 74_37 1 known frame_shift_ins c.3408_3409 p.S1138fs 0.910:1.000 NULL pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom 0 no_errors 0 0 0 50 0 0 43 14 24.56 156 0 0.00 164 42 20.39 SUPT7L 0 genome.wustl.edu 37 2 27878452 27878453 + Frame_Shift_Del DEL AG AG - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AG AG AG - AG AG Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 27878452 27878453 AG 0 DEL SUPT7L ENST00000337768 human ensembl 74_37 -1 known frame_shift_del c.762_761 p.S254fs 0.940:1.000 NULL pfam_BTP,smart_BTP 0 no_errors 0 0 0 29 0 0 19 9 32.14 247 0 0.00 167 71 29.83 RASGRP3 0 genome.wustl.edu 37 2 33749514 33749514 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 33749514 33749514 A 0 DEL RASGRP3 ENST00000402538 human ensembl 74_37 1 known frame_shift_del c.706 p.N237fs 1 pfam_RasGRF_CDC25,superfamily_Ras_GEF_dom,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25 pfam_RasGRF_CDC25,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,smart_EF_hand_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,pfscan_EF_hand_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N,prints_DAG/PE-bd 0 no_errors 0 0 0 69 0 0 41 18 30.51 217 0 0.00 183 68 27.09 HEATR5B 0 genome.wustl.edu 37 2 37276898 37276898 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 37276898 37276898 T 0 DEL HEATR5B ENST00000233099 human ensembl 74_37 -1 known frame_shift_del c.2594 p.N865fs 1 superfamily_ARM-type_fold superfamily_ARM-type_fold 0 no_errors 0 0 0 65 0 0 47 20 29.85 173 0 0.00 178 71 28.51 PPM1B 0 genome.wustl.edu 37 2 44428376 44428377 + Frame_Shift_Del DEL AT AT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AT AT AT - AT AT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 44428376 44428377 AT 0 DEL PPM1B ENST00000282412 human ensembl 74_37 1 known frame_shift_del c.38_39 p.H13fs 1.000:1.000 superfamily_PP2C-like_dom,smart_PP2C-like_dom pfam_PP2C-like_dom,pfam_PP2C_C,superfamily_PP2C-like_dom,superfamily_PP2C_C,smart_PP2C-like_dom 0 no_errors 0 0 0 112 0 0 53 20 27.4 277 0 0.00 246 72 22.64 MSH2 0 genome.wustl.edu 37 2 47639588 47639588 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 47639588 47639588 A 0 DEL MSH2 ENST00000233146 human ensembl 74_37 1 known frame_shift_del c.681 p.A230fs 0.994 pfam_DNA_mmatch_repair_MutS_con_dom,superfamily_DNA_mmatch_repair_MutS_con_dom,pirsf_DNA_mismatch_repair_MSH2 pfam_DNA_mismatch_repair_MutS_C,pfam_DNA_mismatch_repair_MutS_core,pfam_DNA_mmatch_repair_MutS_con_dom,pfam_DNA_mismatch_repair_MutS-lik_N,pfam_DNA_mismatch_repair_MutS_clamp,superfamily_DNA_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_DNA_mmatch_repair_MutS_con_dom,smart_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_C,pirsf_DNA_mismatch_repair_MSH2 0 no_errors rs63749897 GA->G 0 153 0 0 80 24 23.08 228 0 0.00 201 54 21.18 C2orf73 0 genome.wustl.edu 37 2 54587451 54587451 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 54587451 54587451 A 0 DEL C2orf73 ENST00000398634 human ensembl 74_37 1 known frame_shift_del c.616 p.T208fs 0.824 NULL NULL 0 no_errors 0 0 0 53 0 0 34 18 34.62 182 0 0.00 202 43 17.55 TET3 0 genome.wustl.edu 37 2 74329152 74329152 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 74329152 74329152 G 0 DEL TET3 ENST00000409262 human ensembl 74_37 1 known frame_shift_del c.4832 p.G1613fs 1 NULL NULL 0 no_errors 0 0 0 16 0 0 6 5 45.45 20 0 0.00 18 7 28.00 TGOLN2 0 genome.wustl.edu 37 2 85553754 85553756 + In_Frame_Del DEL CTT CTT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 CTT CTT CTT - CTT CTT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 85553754 85553756 CTT 0 DEL TGOLN2 ENST00000377386 human ensembl 74_37 -1 known in_frame_del c.1101_1099 p.K367in_frame_del 0.005:0.004:0.001 NULL NULL 0 no_errors 0 0 0 44 0 0 23 10 30.3 233 0 0.00 148 52 26.00 UNC50 0 genome.wustl.edu 37 2 99232795 99232795 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 99232795 99232795 T 0 DEL UNC50 ENST00000409347 human ensembl 74_37 1 known frame_shift_del c.578 p.F195fs 0.997 pfam_UNC-50 pfam_UNC-50 0 no_errors 0 0 0 104 0 0 59 19 24.36 247 0 0.00 226 88 28.03 SEPT10 0 genome.wustl.edu 37 2 110301828 110301828 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 110301828 110301828 T 0 DEL SEPT10 ENST00000356688 human ensembl 74_37 -1 putative frame_shift_del c.1506 p.K502fs 0.004 NULL pfam_Cell_div_GTP-bd,superfamily_P-loop_NTPase 0 no_errors 0 0 0 216 0 0 123 45 26.79 127 1 0.78 131 28 17.61 CXCR4 0 genome.wustl.edu 37 2 136872415 136872415 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 136872415 136872415 A 0 DEL CXCR4 ENST00000466288 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 52 0 0 25 18 41.86 240 0 0.00 216 74 25.52 RIF1 0 genome.wustl.edu 37 2 152354461 152354462 + RNA INS - - TT TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - TT - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 152354461 152354462 0 TT INS RIF1 ENST00000457745 human ensembl 74_37 1 known rna NULL NULL 0.004:0.007 0 0 0 no_errors 0 0 0 72 0 0 46 17 26.98 55 0 0.00 58 18 23.68 CCDC148 0 genome.wustl.edu 37 2 159077217 159077217 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 159077217 159077217 T 0 DEL CCDC148 ENST00000283233 human ensembl 74_37 -1 known frame_shift_del c.1260 p.K420fs 1 NULL NULL 0 no_errors 0 0 0 146 0 0 57 29 33.72 287 0 0.00 217 93 30.00 XIRP2 0 genome.wustl.edu 37 2 168099958 168099958 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 168099958 168099958 G 0 DEL XIRP2 ENST00000295237 human ensembl 74_37 1 known frame_shift_del c.2056 p.D688fs 0.997 NULL pfam_Actin-binding_Xin_repeat 0 no_errors 0 0 0 45 0 0 21 13 38.24 181 1 0.55 185 73 28.29 RAPGEF4 0 genome.wustl.edu 37 2 173679336 173679337 + RNA INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 173679336 173679337 0 T INS RAPGEF4 ENST00000464976 human ensembl 74_37 1 known rna NULL NULL 0.000:0.000 0 0 0 no_errors 0 0 0 76 0 0 46 16 25.81 310 0 0.00 263 109 29.30 FSIP2 0 genome.wustl.edu 37 2 186665038 186665039 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 186665038 186665039 0 A INS FSIP2 ENST00000343098 human ensembl 74_37 1 known frame_shift_ins c.11272_11273 p.N3760fs 0.256:0.278 NULL NULL 0 no_errors 0 0 0 163 0 0 95 27 22.13 245 0 0.00 223 91 28.98 ZDBF2 0 genome.wustl.edu 37 2 207174428 207174428 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 207174428 207174428 A 0 DEL ZDBF2 ENST00000374423 human ensembl 74_37 1 known frame_shift_del c.5176 p.K1728fs 0 NULL pfam_Znf_DBF,smart_Znf_DBF 0 no_errors 0 0 0 50 0 0 26 6 18.75 200 1 0.50 172 81 32.02 SMARCAL1 0 genome.wustl.edu 37 2 217300192 217300192 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 217300192 217300192 A 0 DEL SMARCAL1 ENST00000357276 human ensembl 74_37 1 known frame_shift_del c.1617 p.T541fs 0 pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd pfam_HARP_dom,pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C 0 no_errors 0 0 0 81 0 0 58 15 20.55 288 1 0.35 268 97 26.58 TMBIM1 0 genome.wustl.edu 37 2 219143774 219143777 + Frame_Shift_Del DEL AGAC AGAC - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AGAC AGAC AGAC - AGAC AGAC Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 219143774 219143777 AGAC 0 DEL TMBIM1 ENST00000258412 human ensembl 74_37 -1 known frame_shift_del c.409_406 p.V136fs 0.998:0.324:0.373:0.084 pfam_Bax_inhibitor_1-related pfam_Bax_inhibitor_1-related 0 no_errors 0 0 0 31 0 0 21 4 16 145 0 0.00 129 33 20.37 IRS1 0 genome.wustl.edu 37 2 227661663 227661664 + Frame_Shift_Ins INS - - CC TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - CC - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 227661663 227661664 0 CC INS IRS1 ENST00000305123 human ensembl 74_37 -1 known frame_shift_ins c.1792_1791 p.H597fs 1.000:0.995 NULL pfam_Insln_rcpt_S1,pfam_Pleckstrin_homology,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,prints_Insln_rcpt_S1,pfscan_Pleckstrin_homology,pfscan_Insln_rcpt_S1 0 no_errors 0 0 0 63 0 0 27 9 25 49 0 0.00 85 14 14.14 COL6A3 0 genome.wustl.edu 37 2 238232746 238232747 + RNA DEL CA CA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 CA CA CA - CA CA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 238232746 238232747 CA 0 DEL COL6A3 ENST00000473258 human ensembl 74_37 -1 known rna NULL NULL 0.001:0.000 0 0 0 no_errors 0 0 0 108 1 0.92 55 7 11.29 108 0 0.00 122 21 14.69 KIF9 0 genome.wustl.edu 37 3 47315092 47315092 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 47315092 47315092 C 0 DEL KIF9 ENST00000265529 human ensembl 74_37 -1 known frame_shift_del c.316 p.A106fs 0.868 pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom 0 no_errors 0 0 0 42 0 0 13 16 55.17 189 1 0.53 64 55 46.22 DNAH1 0 genome.wustl.edu 37 3 52420699 52420699 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 52420699 52420699 C 0 DEL DNAH1 ENST00000420323 human ensembl 74_37 1 known frame_shift_del c.8833 p.P2946fs 0.993 NULL pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase 0 no_errors 0 0 0 46 0 0 20 16 44.44 63 0 0.00 44 21 32.31 STAB1 0 genome.wustl.edu 37 3 52543930 52543930 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 52543930 52543930 G 0 DEL STAB1 ENST00000321725 human ensembl 74_37 1 known frame_shift_del c.2392 p.V800fs 0.999 smart_EG-like_dom pfam_FAS1_domain,pfam_Link,superfamily_C-type_lectin_fold,superfamily_FAS1_domain,smart_EG-like_dom,smart_EGF_laminin,smart_FAS1_domain,smart_EGF-like_Ca-bd_dom,smart_Link,pfscan_EG-like_dom,pfscan_FAS1_domain,pfscan_Link 0 no_errors 0 0 0 35 0 0 16 7 30.43 93 0 0.00 38 32 45.71 PBRM1 0 genome.wustl.edu 37 3 52637589 52637589 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 52637589 52637589 T 0 DEL PBRM1 ENST00000296302 human ensembl 74_37 -1 known frame_shift_del c.2727 p.K909fs 1 NULL pfam_Bromodomain,pfam_BAH_dom,pfam_HMG_box_dom,superfamily_Bromodomain,superfamily_HMG_box_dom,smart_Bromodomain,smart_BAH_dom,smart_HMG_box_dom,pfscan_BAH_dom,pfscan_HMG_box_dom,pfscan_Bromodomain,prints_Bromodomain 0 no_errors 0 0 0 73 0 0 34 21 38.18 301 0 0.00 175 126 41.86 ENSG00000243696 0 genome.wustl.edu 37 3 52864443 52864443 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 52864443 52864443 T 0 DEL ENSG00000243696 ENST00000513520 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 17 0 0 3 4 57.14 134 2 1.47 78 51 39.53 PRICKLE2-AS1 0 genome.wustl.edu 37 3 64083340 64083341 + RNA INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 64083340 64083341 0 T INS PRICKLE2-AS1 ENST00000482609 human ensembl 74_37 1 known rna NULL NULL 0.004:0.008 0 0 0 no_errors 0 0 0 82 0 0 44 6 12 295 0 0.00 224 11 4.68 ROBO1 0 genome.wustl.edu 37 3 78710235 78710235 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 78710235 78710235 A 0 DEL ROBO1 ENST00000464233 human ensembl 74_37 -1 known frame_shift_del c.2265 p.F755fs 1 superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom 0 no_errors 0 0 0 91 0 0 42 20 32.26 291 0 0.00 123 71 36.60 PLXNA1 0 genome.wustl.edu 37 3 126751234 126751234 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 126751234 126751234 C 0 DEL PLXNA1 ENST00000393409 human ensembl 74_37 1 known frame_shift_del c.5236 p.L1747fs 1 pfam_Plexin_cytoplasmic_RasGAP_dom,superfamily_Rho_GTPase_activation_prot pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom 0 no_errors 0 0 0 20 0 0 13 10 43.48 74 0 0.00 71 21 22.83 RUVBL1 0 genome.wustl.edu 37 3 127817784 127817784 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 127817784 127817784 C 0 DEL RUVBL1 ENST00000322623 human ensembl 74_37 -1 known frame_shift_del c.758 p.G253fs 0.997 pfam_TIP49_C,superfamily_P-loop_NTPase,smart_AAA+_ATPase pfam_TIP49_C,pfam_DNA_helicase_Holl-junc_RuvB_N,pfam_ATPase_AAA_core,superfamily_P-loop_NTPase,superfamily_NA-bd_OB-fold,smart_AAA+_ATPase 0 no_errors 0 0 0 36 0 0 22 7 24.14 160 0 0.00 210 41 16.33 C3orf27 0 genome.wustl.edu 37 3 128292318 128292319 + Frame_Shift_Ins INS - - TC TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - TC - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 128292318 128292319 0 TC INS C3orf27 ENST00000356020 human ensembl 74_37 -1 known frame_shift_ins c.255_254 p.D85fs 0.000:0.075 NULL NULL 0 no_errors 0 0 0 25 0 0 29 8 21.62 66 0 0.00 106 20 15.87 ASTE1 0 genome.wustl.edu 37 3 130733047 130733048 + Frame_Shift_Del DEL TT TT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TT TT TT - TT TT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 130733047 130733048 TT 0 DEL ASTE1 ENST00000264992 human ensembl 74_37 -1 known frame_shift_del c.1894_1893 p.R632fs 0.014:0.001 NULL pfam_XPG_DNA_repair_N 0 no_errors 0 0 0 17 0 0 16 7 30.43 99 0 0.00 120 34 22.08 SSR3 0 genome.wustl.edu 37 3 156266627 156266627 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 156266627 156266627 A 0 DEL SSR3 ENST00000464138 human ensembl 74_37 -1 putative rna NULL NULL 0.002 0 0 0 no_errors 0 0 0 75 0 0 50 11 18.03 238 0 0.00 318 71 18.25 ABCC5 0 genome.wustl.edu 37 3 183665257 183665257 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 183665257 183665257 A 0 DEL ABCC5 ENST00000334444 human ensembl 74_37 -1 known frame_shift_del c.3269 p.L1090fs 1 pfam_ABC_transptr_TM_dom,superfamily_ABC1_TM_dom,pfscan_ABC1_TM_dom pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC1_TM_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom 0 no_errors 0 0 0 39 0 0 34 8 19.05 151 0 0.00 144 39 21.31 DNAJB11 0 genome.wustl.edu 37 3 186314953 186314955 + In_Frame_Del DEL GGA GGA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 GGA GGA GGA - GGA GGA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 186314953 186314955 GGA 0 DEL DNAJB11 ENST00000538831 human ensembl 74_37 1 known in_frame_del c.189_191 p.E65in_frame_del 0.003:0.002:0.002 pfam_DUF2346 pfam_DUF2346 0 no_errors 0 0 0 95 0 0 71 20 21.98 38 0 0.00 53 7 11.67 MB21D2 0 genome.wustl.edu 37 3 192516279 192516280 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 192516279 192516280 0 T INS MB21D2 ENST00000392452 human ensembl 74_37 -1 known frame_shift_ins c.1372_1371 p.L457fs 1.000:1.000 NULL pfam_Mab-21_dom 0 no_errors rs34835215 G->GT 0 28 0 0 17 12 41.38 205 0 0.00 239 50 17.30 UBXN7-AS1 0 genome.wustl.edu 37 3 196159010 196159011 + RNA INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 196159010 196159011 0 G INS UBXN7-AS1 ENST00000598881 human ensembl 74_37 1 known rna NULL NULL 0.003:0.004 0 0 0 no_errors 0 0 0 23 0 0 50 7 12.28 13 0 0.00 19 4 17.39 CPZ 0 genome.wustl.edu 37 4 8609110 8609110 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 8609110 8609110 C 0 DEL CPZ ENST00000360986 human ensembl 74_37 1 known frame_shift_del c.1185 p.Q397fs 0.997 pfam_Peptidase_M14,smart_Peptidase_M14 pfam_Peptidase_M14,pfam_Frizzled_dom,superfamily_Frizzled_dom,superfamily_CarboxyPept-like_regulatory,smart_Frizzled_dom,smart_Peptidase_M14,prints_Peptidase_M14,pfscan_Frizzled_dom 0 no_errors 0 0 0 55 0 0 22 9 29.03 154 0 0.00 129 52 28.73 TBC1D1 0 genome.wustl.edu 37 4 38134424 38134427 + RNA DEL TTTT TTTT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TTTT TTTT TTTT - TTTT TTTT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 38134424 38134427 TTTT 0 DEL TBC1D1 ENST00000405444 human ensembl 74_37 1 known rna NULL NULL 0.018:0.027:0.074:0.101 0 0 0 no_errors 0 0 0 166 0 0 68 10 12.82 65 1 1.52 66 23 25.84 FIP1L1 0 genome.wustl.edu 37 4 54319247 54319248 + Frame_Shift_Ins INS - - AG TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - AG - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 54319247 54319248 0 AG INS FIP1L1 ENST00000337488 human ensembl 74_37 1 known frame_shift_ins c.1446_1447 p.E486fs 0.997:0.975 NULL pfam_Fip1 0 no_errors 0 0 0 33 0 0 16 6 27.27 94 1 1.05 122 29 19.21 CENPC 0 genome.wustl.edu 37 4 68379808 68379808 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 68379808 68379808 T 0 DEL CENPC ENST00000273853 human ensembl 74_37 -1 known frame_shift_del c.1428 p.K476fs 0.061 NULL pfam_Mif2/CENP-C_cupin,pfam_Cupin_2,superfamily_RmlC_Cupin 0 no_errors 0 0 0 91 0 0 48 16 25 266 0 0.00 185 63 25.40 UGT2A3 0 genome.wustl.edu 37 4 69795582 69795583 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 69795582 69795583 0 A INS UGT2A3 ENST00000251566 human ensembl 74_37 -1 known frame_shift_ins c.1533_1532 p.L511fs 0.027:0.056 pfam_UDP_glucos_trans pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C 0 no_errors 0 0 0 84 0 0 45 25 35.71 86 0 0.00 45 17 27.42 COX18 0 genome.wustl.edu 37 4 73930982 73930982 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 73930982 73930982 C 0 DEL COX18 ENST00000295890 human ensembl 74_37 -1 known frame_shift_del c.583 p.A195fs 0.018 pfam_Membrane_insert_OXA1/ALB3/YidC pfam_Membrane_insert_OXA1/ALB3/YidC 0 no_errors 0 0 0 79 0 0 65 19 22.62 107 0 0.00 74 29 28.16 CDKL2 0 genome.wustl.edu 37 4 76539580 76539580 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 76539580 76539580 T 0 DEL CDKL2 ENST00000429927 human ensembl 74_37 -1 known frame_shift_del c.222 p.K74fs 0.979 pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 74 0 0 35 18 33.96 333 0 0.00 307 115 27.25 SEC31A 0 genome.wustl.edu 37 4 83785565 83785565 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 83785565 83785565 T 0 DEL SEC31A ENST00000432794 human ensembl 74_37 -1 known frame_shift_del c.1384 p.I462fs 0.985 NULL pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors 0 0 0 81 0 0 49 20 28.99 210 1 0.47 137 74 35.07 ATOH1 0 genome.wustl.edu 37 4 94750382 94750382 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 94750382 94750382 G 0 DEL ATOH1 ENST00000306011 human ensembl 74_37 1 known frame_shift_del c.305 p.E104fs 0.113 NULL pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom 0 no_errors 0 0 0 25 0 0 13 7 35 30 0 0.00 19 3 13.64 FAT4 0 genome.wustl.edu 37 4 126371577 126371578 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 126371577 126371578 0 T INS FAT4 ENST00000394329 human ensembl 74_37 1 known frame_shift_ins c.9406_9407 p.A3138fs 0.984:0.992 pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin 0 no_errors 0 0 0 50 0 0 32 15 31.91 184 0 0.00 160 85 34.69 SORBS2 0 genome.wustl.edu 37 4 186515044 186515044 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 186515044 186515044 C 0 DEL SORBS2 ENST00000284776 human ensembl 74_37 -1 known frame_shift_del c.3130 p.E1044fs 1 superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain pfam_SH3_domain,pfam_SH3_2,pfam_Sorb,superfamily_SH3_domain,smart_Sorb,smart_SH3_domain,pfscan_Sorb,pfscan_SH3_domain,prints_SH3_domain,prints_p67phox 0 no_errors 0 0 0 102 0 0 60 33 35.48 258 1 0.39 264 98 27.07 PLEKHG4B 0 genome.wustl.edu 37 5 163580 163580 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 163580 163580 C 0 DEL PLEKHG4B ENST00000283426 human ensembl 74_37 1 known frame_shift_del c.2325 p.P777fs 0.999 NULL pfam_DH-domain,superfamily_DH-domain,superfamily_CRAL-TRIO_dom,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain 0 no_errors 0 0 0 45 0 0 39 11 22 45 0 0.00 41 15 26.79 MYO10 0 genome.wustl.edu 37 5 16694605 16694606 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 16694605 16694606 0 C INS MYO10 ENST00000513610 human ensembl 74_37 -1 known frame_shift_ins c.3675_3674 p.S1226fs 1.000:1.000 pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology pfam_Myosin_head_motor_dom,pfam_MyTH4_dom,pfam_Pleckstrin_homology,pfam_FERM_central,pfam_IQ_motif_EF-hand-BS,pfam_Ras-assoc,superfamily_P-loop_NTPase,superfamily_FERM_central,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,smart_Pleckstrin_homology,smart_MyTH4_dom,smart_Band_41_domain,pfscan_FERM_domain,pfscan_IQ_motif_EF-hand-BS,pfscan_MyTH4_dom,pfscan_Pleckstrin_homology,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 34 0 0 33 5 13.16 172 1 0.58 172 32 15.69 LMBRD2 0 genome.wustl.edu 37 5 36122474 36122474 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 36122474 36122474 T 0 DEL LMBRD2 ENST00000296603 human ensembl 74_37 -1 known frame_shift_del c.1028 p.N343fs 1 pfam_LMBR1-like_membr_prot pfam_LMBR1-like_membr_prot 0 no_errors 0 0 0 152 0 0 73 24 24.74 222 0 0.00 226 84 27.10 NIPBL 0 genome.wustl.edu 37 5 36984789 36984789 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 36984789 36984789 A 0 DEL NIPBL ENST00000282516 human ensembl 74_37 1 known frame_shift_del c.1507 p.R505fs 1 NULL superfamily_ARM-type_fold 0 no_errors rs34314728 GA->G 0 77 0 0 59 20 25.32 126 0 0.00 117 36 23.53 CARD6 0 genome.wustl.edu 37 5 40853094 40853094 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 40853094 40853094 T 0 DEL CARD6 ENST00000254691 human ensembl 74_37 1 known frame_shift_del c.1660 p.F556fs 0.998 NULL pfam_CARD,superfamily_DEATH-like_dom,smart_CARD,pfscan_CARD 0 no_errors 0 0 0 68 1 1.45 53 19 26.39 271 0 0.00 221 95 30.06 PLK2 0 genome.wustl.edu 37 5 57753012 57753012 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 57753012 57753012 A 0 DEL PLK2 ENST00000274289 human ensembl 74_37 -1 known frame_shift_del c.1004 p.L335fs 1 superfamily_Kinase-like_dom pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_POLO_box_duplicated_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_POLO_box_duplicated_dom,pfscan_Prot_kinase_dom 0 no_errors 0 0 0 42 0 0 40 9 18.37 171 1 0.58 171 81 32.14 CENPH 0 genome.wustl.edu 37 5 68492902 68492902 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 68492902 68492902 A 0 DEL CENPH ENST00000283006 human ensembl 74_37 1 known frame_shift_del c.337 p.N115fs 0.089 NULL pfam_CENP-H 0 no_errors 0 0 0 85 0 0 42 18 30 301 0 0.00 184 77 29.50 BDP1 0 genome.wustl.edu 37 5 70805889 70805889 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 70805889 70805889 A 0 DEL BDP1 ENST00000358731 human ensembl 74_37 1 known frame_shift_del c.2970 p.I992fs 0 NULL superfamily_Homeodomain-like,smart_SANT/Myb 0 no_errors 0 0 0 63 0 0 27 16 37.21 97 0 0.00 80 29 26.61 TCERG1 0 genome.wustl.edu 37 5 145886723 145886723 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 145886723 145886723 A 0 DEL TCERG1 ENST00000296702 human ensembl 74_37 1 known frame_shift_del c.2863 p.K957fs 1 pfam_FF_domain,superfamily_FF_domain,smart_FF_domain pfam_FF_domain,pfam_WW_dom,superfamily_FF_domain,superfamily_WW_dom,smart_WW_dom,smart_FF_domain,pfscan_WW_dom 0 no_errors 0 0 0 74 0 0 37 11 22.92 189 0 0.00 141 63 30.88 ZKSCAN4 0 genome.wustl.edu 37 6 28212908 28212908 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 28212908 28212908 T 0 DEL ZKSCAN4 ENST00000377294 human ensembl 74_37 -1 known frame_shift_del c.1624 p.T542fs 0.001 pfscan_Znf_C2H2 pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN 0 no_errors 0 0 0 50 0 0 25 11 30.56 234 0 0.00 196 68 25.76 OR2J1 0 genome.wustl.edu 37 6 29068729 29068729 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 29068729 29068729 A 0 DEL OR2J1 ENST00000377171 human ensembl 74_37 1 known frame_shift_del c.10 p.N6fs 0 NULL pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,prints_Olfact_rcpt,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM 0 no_errors 0 0 0 66 0 0 53 16 23.19 222 1 0.45 218 108 33.13 C6orf89 0 genome.wustl.edu 37 6 36867370 36867371 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 36867370 36867371 0 C INS C6orf89 ENST00000355190 human ensembl 74_37 1 known frame_shift_ins c.171_172 p.Q60fs 0.997:0.991 NULL NULL 0 no_errors 0 0 0 43 0 0 30 19 38.78 254 0 0.00 157 131 45.49 LRFN2 0 genome.wustl.edu 37 6 40360357 40360357 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 40360357 40360357 G 0 DEL LRFN2 ENST00000338305 human ensembl 74_37 -1 known frame_shift_del c.1695 p.S566fs 0 NULL pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like_dom 0 no_errors 0 0 0 9 0 0 5 4 44.44 52 0 0.00 51 15 22.73 TDRD6 0 genome.wustl.edu 37 6 46660150 46660150 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 46660150 46660150 A 0 DEL TDRD6 ENST00000316081 human ensembl 74_37 1 known frame_shift_del c.4285 p.N1430fs 0 NULL pfam_Tudor,smart_Tudor,pfscan_Tudor 0 no_errors 0 0 0 44 0 0 29 8 21.62 255 0 0.00 154 68 30.63 ENSG00000243501 0 genome.wustl.edu 37 6 73951945 73951946 + Frame_Shift_Del DEL TA TA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TA TA TA - TA TA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 73951945 73951946 TA 0 DEL ENSG00000243501 ENST00000423730 human ensembl 74_37 -1 known frame_shift_del c.128_127 p.Y43fs 0.020:0.004 NULL NULL 0 no_errors 0 0 0 31 0 0 21 6 22.22 71 0 0.00 53 22 29.33 EEF1A1 0 genome.wustl.edu 37 6 74228114 74228114 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 74228114 74228114 T 0 DEL EEF1A1 ENST00000309268 human ensembl 74_37 -1 known frame_shift_del c.992 p.N331fs 1 superfamily_Transl_B-barrel,tigrfam_Transl_elong_EF1A_euk/arc pfam_EF_GTP-bd_dom,pfam_Transl_elong_EFTu/EF1A_C,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Transl_elong_EF1A/Init_IF2_C,superfamily_Transl_B-barrel,prints_EF_GTP-bd_dom,tigrfam_Transl_elong_EF1A_euk/arc 0 no_errors 0 0 0 80 0 0 42 18 30 40 0 0.00 33 6 15.38 MYO6 0 genome.wustl.edu 37 6 76599858 76599858 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 76599858 76599858 A 0 DEL MYO6 ENST00000369981 human ensembl 74_37 1 known frame_shift_del c.2743 p.K917fs 1 NULL pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom 0 no_errors 0 0 0 63 0 0 42 15 26.32 172 0 0.00 135 36 21.05 ZNF292 0 genome.wustl.edu 37 6 87967203 87967204 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 87967203 87967204 0 T INS ZNF292 ENST00000369577 human ensembl 74_37 1 known frame_shift_ins c.3856_3857 p.S1288fs 1.000:1.000 NULL smart_Znf_C2H2-like,pfscan_Znf_C2H2 0 no_errors 0 0 0 61 0 0 46 21 31.34 279 0 0.00 202 70 25.74 ORC3 0 genome.wustl.edu 37 6 88318838 88318838 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 88318838 88318838 A 0 DEL ORC3 ENST00000257789 human ensembl 74_37 1 known frame_shift_del c.604 p.R204fs 1 pfam_ORC3 pfam_ORC3 0 no_errors 0 0 0 136 0 0 94 38 28.79 274 1 0.36 242 85 25.99 MANEA 0 genome.wustl.edu 37 6 96034870 96034871 + Frame_Shift_Del DEL TA TA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TA TA TA - TA TA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 96034870 96034871 TA 0 DEL MANEA ENST00000369293 human ensembl 74_37 1 known frame_shift_del c.555_556 p.Y189fs 0.026:0.048 NULL NULL 0 no_errors 0 0 0 146 0 0 77 21 21.43 191 1 0.52 165 50 23.26 SEC63 0 genome.wustl.edu 37 6 108214755 108214756 + Frame_Shift_Del DEL TT TT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TT TT TT - TT TT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 108214755 108214756 TT 0 DEL SEC63 ENST00000369002 human ensembl 74_37 -1 known frame_shift_del c.1605_1604 p.K535fs 0.959:1.000 superfamily_ARM-type_fold,smart_Sec63-dom pfam_Sec63-dom,pfam_DnaJ_domain,superfamily_DnaJ_domain,superfamily_ARM-type_fold,smart_DnaJ_domain,smart_Sec63-dom,prints_DnaJ_domain,pfscan_DnaJ_domain 0 no_errors 0 0 0 86 0 0 58 24 29.27 130 0 0.00 111 43 27.92 AK9 0 genome.wustl.edu 37 6 109850191 109850191 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 109850191 109850191 A 0 DEL AK9 ENST00000355283 human ensembl 74_37 -1 novel frame_shift_del c.893 p.F298fs 0.005 NULL pfam_Adenylate_kin,pfam_YHS_dom,pfam_ATPase_AAA_core,superfamily_P-loop_NTPase 0 no_errors 0 0 0 105 0 0 56 22 28.21 131 0 0.00 127 51 28.65 AKAP7 0 genome.wustl.edu 37 6 131481276 131481276 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 131481276 131481276 A 0 DEL AKAP7 ENST00000368123 human ensembl 74_37 1 known frame_shift_del c.163 p.K57fs 0.449 pfam_Kinase-A_anchor_nucl_local_sig pfam_Kinase-A_anchor_nucl_local_sig,pfam_Kinase-A_anchor_RI-RII-bd_dom,superfamily_RNA_ligase/cNuc_Pdiesterase 0 no_errors 0 0 0 95 1 1.04 67 20 22.99 249 0 0.00 173 71 29.10 MYB 0 genome.wustl.edu 37 6 135539912 135539912 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 135539912 135539912 T 0 DEL MYB ENST00000531845 human ensembl 74_37 1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 67 1 1.47 42 26 38.24 237 0 0.00 210 59 21.93 AGPAT4 0 genome.wustl.edu 37 6 161560589 161560589 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 161560589 161560589 G 0 DEL AGPAT4 ENST00000320285 human ensembl 74_37 -1 known frame_shift_del c.907 p.R303fs 0.011 NULL pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase 0 no_errors 0 0 0 73 0 0 46 11 19.3 89 1 1.11 68 32 32.00 LINC00473 0 genome.wustl.edu 37 6 166401104 166401104 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 6 166401104 166401104 A 0 DEL LINC00473 ENST00000444465 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 39 0 0 20 10 33.33 89 0 0.00 77 15 16.30 TOMM7 0 genome.wustl.edu 37 7 22857031 22857032 + Frame_Shift_Del DEL TT TT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TT TT TT - TT TT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 22857031 22857032 TT 0 DEL TOMM7 ENST00000372879 human ensembl 74_37 -1 putative frame_shift_del c.289_288 p.K96fs 0.100:0.100 NULL pfam_Tom7 0 no_errors 0 0 0 50 0 0 29 10 25.64 94 0 0.00 56 20 26.32 TRA2A 0 genome.wustl.edu 37 7 23561888 23561888 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 23561888 23561888 A 0 DEL TRA2A ENST00000490942 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 108 0 0 42 28 40 87 0 0.00 82 27 24.77 HOXA9 0 genome.wustl.edu 37 7 27202965 27202966 + RNA INS - - CC TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - CC - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 27202965 27202966 0 CC INS HOXA9 ENST00000487384 human ensembl 74_37 -1 known rna NULL NULL 1.000:0.997 0 0 0 no_errors 0 0 0 56 0 0 19 6 24 221 0 0.00 243 67 21.61 HOXA9 0 genome.wustl.edu 37 7 27202966 27202966 + RNA DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 27202966 27202966 C 0 DEL HOXA9 ENST00000487384 human ensembl 74_37 -1 known rna NULL NULL 0.997 0 0 0 no_errors 0 0 0 56 0 0 15 9 37.5 221 0 0.00 226 84 27.10 HOXA10 0 genome.wustl.edu 37 7 27213495 27213495 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 27213495 27213495 G 0 DEL HOXA10 ENST00000283921 human ensembl 74_37 -1 known frame_shift_del c.431 p.P144fs 0.999 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa 0 no_errors 0 0 0 18 0 0 19 7 26.92 24 0 0.00 21 7 25.00 NSUN5 0 genome.wustl.edu 37 7 72718307 72718309 + In_Frame_Del DEL TCC TCC - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TCC TCC TCC - TCC TCC Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 72718307 72718309 TCC 0 DEL NSUN5 ENST00000438747 human ensembl 74_37 -1 known in_frame_del c.854_852 p.E284in_frame_del 1.000:1.000:0.852 pfam_Fmu/NOL1/Nop2p pfam_Fmu/NOL1/Nop2p,prints_RCMT 0 no_errors 0 0 0 51 0 0 39 5 11.36 60 0 0.00 44 18 29.03 SRRT 0 genome.wustl.edu 37 7 100479358 100479358 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 100479358 100479358 C 0 DEL SRRT ENST00000388793 human ensembl 74_37 1 known frame_shift_del c.330 p.P112fs 1 NULL pfam_Arsenite-R_2,pfam_DUF3546 0 no_errors 0 0 0 14 0 0 14 8 36.36 25 0 0.00 22 9 29.03 TRIM56 0 genome.wustl.edu 37 7 100731858 100731858 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 100731858 100731858 A 0 DEL TRIM56 ENST00000306085 human ensembl 74_37 1 known frame_shift_del c.1265 p.A424fs 0.002 NULL pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_CheY-like_superfamily,smart_Znf_RING,smart_Znf_B-box,pfscan_Znf_B-box,pfscan_Znf_RING 0 no_errors 0 0 0 55 0 0 36 4 10 136 0 0.00 114 58 33.72 DOCK4 0 genome.wustl.edu 37 7 111405191 111405192 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 111405191 111405192 0 T INS DOCK4 ENST00000428084 human ensembl 74_37 -1 known frame_shift_ins c.4003_4002 p.F1334fs 1.000:0.955 NULL pfam_DOCK_C,pfam_SH3_2,superfamily_SH3_domain,superfamily_Rho_GTPase_activation_prot,superfamily_C2_dom,smart_SH3_domain,pfscan_SH3_domain 0 no_errors 0 0 0 154 0 0 84 33 28.21 140 0 0.00 133 34 20.36 WNT16 0 genome.wustl.edu 37 7 120971879 120971879 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 120971879 120971879 G 0 DEL WNT16 ENST00000222462 human ensembl 74_37 1 known frame_shift_del c.494 p.G167fs 1 pfam_Wnt,smart_Wnt,prints_Wnt pfam_Wnt,smart_Wnt,prints_Wnt16,prints_Wnt 0 no_errors 0 0 0 48 0 0 19 7 26.92 129 1 0.77 142 52 26.80 IRF5 0 genome.wustl.edu 37 7 128588315 128588317 + In_Frame_Del DEL TCT TCT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TCT TCT TCT - TCT TCT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 128588315 128588317 TCT 0 DEL IRF5 ENST00000357234 human ensembl 74_37 1 known in_frame_del c.1232_1234 p.F413in_frame_del 1.000:0.999:1.000 pfam_Interferon_reg_factor-3,superfamily_SMAD_FHA_domain pfam_Interferon_reg_factor-3,pfam_Interferon_reg_fact_DNA-bd_dom,superfamily_SMAD_FHA_domain,smart_Interferon_reg_fact_DNA-bd_dom,prints_Interferon_reg_fact_DNA-bd_dom 0 no_errors 0 0 0 34 0 0 32 7 17.95 216 0 0.00 182 62 25.41 NDUFB2-AS1 0 genome.wustl.edu 37 7 140395526 140395526 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 140395526 140395526 G 0 DEL NDUFB2-AS1 ENST00000465466 human ensembl 74_37 -1 known rna NULL NULL 0.023 0 0 0 no_errors 0 0 0 57 0 0 42 18 30 49 0 0.00 60 12 16.67 ZNF425 0 genome.wustl.edu 37 7 148809437 148809437 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 148809437 148809437 T 0 DEL ZNF425 ENST00000484196 human ensembl 74_37 -1 known rna NULL NULL 0.013 0 0 0 no_errors 0 0 0 36 0 0 28 11 28.21 80 0 0.00 81 20 19.80 ENSG00000244151 0 genome.wustl.edu 37 7 150773332 150773332 + RNA DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 150773332 150773332 C 0 DEL ENSG00000244151 ENST00000485974 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 65 1 1.52 46 14 23.33 204 0 0.00 109 51 31.87 KMT2C 0 genome.wustl.edu 37 7 151874148 151874148 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 151874148 151874148 T 0 DEL KMT2C ENST00000355193 human ensembl 74_37 -1 known frame_shift_del c.8390 p.K2797fs 0.019 NULL pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_DHHC_palmitoyltrfase,pfscan_Znf_PHD-finger,pfscan_Znf_RING 0 no_errors 0 0 0 89 1 1.11 44 22 33.33 281 2 0.71 237 91 27.74 RP1L1 0 genome.wustl.edu 37 8 10467550 10467552 + In_Frame_Del DEL TCT TCT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TCT TCT TCT - TCT TCT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 10467550 10467552 TCT 0 DEL RP1L1 ENST00000382483 human ensembl 74_37 -1 known in_frame_del c.4058_4056 p.E1353in_frame_del 0.000:0.000:0.000 NULL pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom 0 no_errors 0 0 0 86 0 0 55 11 16.67 191 0 0.00 216 49 18.49 SLC7A2 0 genome.wustl.edu 37 8 17402081 17402081 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 17402081 17402081 T 0 DEL SLC7A2 ENST00000004531 human ensembl 74_37 1 known frame_shift_del c.618 p.F208fs 0.996 pfam_AA-permease/SLC12A_dom,tigrfam_Cat_AA_permease pfam_AA-permease/SLC12A_dom,tigrfam_Cat_AA_permease 0 no_errors 0 0 0 105 0 0 76 17 18.28 211 0 0.00 188 57 23.27 PSD3 0 genome.wustl.edu 37 8 18413785 18413785 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 18413785 18413785 G 0 DEL PSD3 ENST00000440756 human ensembl 74_37 -1 known frame_shift_del c.2868 p.D957fs 0 NULL pfam_Sec7_dom,pfam_Pleckstrin_homology,superfamily_Sec7_dom,smart_Sec7_dom,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_Sec7_dom 0 no_errors 0 0 0 65 0 0 33 13 28.26 186 0 0.00 166 65 28.14 DOCK5 0 genome.wustl.edu 37 8 25257429 25257429 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 25257429 25257429 T 0 DEL DOCK5 ENST00000276440 human ensembl 74_37 1 known frame_shift_del c.4707 p.F1571fs 0.166 pfam_DOCK_C pfam_DOCK_C,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_ARM-type_fold,smart_SH3_domain,pfscan_SH3_domain 0 no_errors 0 0 0 37 0 0 26 11 29.73 224 0 0.00 175 54 23.58 INTS9 0 genome.wustl.edu 37 8 28645389 28645392 + Frame_Shift_Del DEL TGTT TGTT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TGTT TGTT TGTT - TGTT TGTT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 28645389 28645392 TGTT 0 DEL INTS9 ENST00000521022 human ensembl 74_37 -1 known frame_shift_del c.1055_1052 p.K351fs 1.000:1.000:0.993:1.000 pfam_Beta_Casp pfam_Beta_Casp 0 no_errors 0 0 0 45 0 0 35 6 14.63 210 0 0.00 200 58 22.48 ERLIN2 0 genome.wustl.edu 37 8 37611633 37611633 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 37611633 37611633 A 0 DEL ERLIN2 ENST00000276461 human ensembl 74_37 1 known frame_shift_del c.1020 p.*340fs 0.656 NULL pfam_Band_7,smart_Band_7 0 no_errors 0 0 0 51 0 0 28 12 30 196 0 0.00 193 64 24.90 CLVS1 0 genome.wustl.edu 37 8 62412295 62412296 + RNA DEL TT TT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TT TT TT - TT TT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 62412295 62412296 TT 0 DEL CLVS1 ENST00000518858 human ensembl 74_37 1 known rna NULL NULL 0.005:0.005 0 0 0 no_errors 0 0 0 53 0 0 32 13 28.89 140 0 0.00 181 62 25.51 PEX2 0 genome.wustl.edu 37 8 77912372 77912373 + RNA DEL AA AA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AA AA AA - AA AA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 77912372 77912373 AA 0 DEL PEX2 ENST00000520203 human ensembl 74_37 -1 known rna NULL NULL 0.004:0.003 0 0 0 no_errors 0 0 0 37 0 0 14 7 33.33 36 0 0.00 42 12 22.22 SLC26A7 0 genome.wustl.edu 37 8 92352747 92352747 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 92352747 92352747 A 0 DEL SLC26A7 ENST00000309536 human ensembl 74_37 1 known frame_shift_del c.994 p.K333fs 1 pfam_Sulph_transpt pfam_Sulph_transpt,pfam_STAS_dom,superfamily_STAS_dom,pfscan_STAS_dom 0 no_errors 0 0 0 43 0 0 30 9 23.08 162 0 0.00 157 58 26.98 RAD54B 0 genome.wustl.edu 37 8 95390551 95390552 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 95390551 95390552 0 C INS RAD54B ENST00000336148 human ensembl 74_37 -1 known frame_shift_ins c.2372_2371 p.A791fs 1.000:1.000 pfam_HDA_complex_subunit-2/3,superfamily_P-loop_NTPase,pfscan_Helicase_C pfam_SNF2_N,pfam_Helicase_C,pfam_Helicase/UvrB_dom,pfam_HDA_complex_subunit-2/3,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C 0 no_errors 0 0 0 35 0 0 39 9 18.75 249 0 0.00 187 88 32.00 DCAF13 0 genome.wustl.edu 37 8 104439487 104439487 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 104439487 104439487 T 0 DEL DCAF13 ENST00000519682 human ensembl 74_37 1 putative frame_shift_del c.619 p.F209fs 0.001 NULL pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom 0 no_errors rs566617241 GT->G 0 83 0 0 46 27 36.99 219 1 0.45 188 51 21.34 DPYS 0 genome.wustl.edu 37 8 105440214 105440214 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 8 105440214 105440214 T 0 DEL DPYS ENST00000351513 human ensembl 74_37 -1 known frame_shift_del c.1086 p.G363fs 1 pfam_Amidohydro_1,superfamily_Metal-dep_hydrolase_composite,tigrfam_Hydantoinase/dihydroPyrase pfam_Amidohydro_1,superfamily_Metal-dep_hydrolase_composite,tigrfam_Hydantoinase/dihydroPyrase 0 no_errors 0 0 0 96 1 1.03 53 21 28.38 216 2 0.92 202 84 29.37 VCP 0 genome.wustl.edu 37 9 35059647 35059647 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 35059647 35059647 T 0 DEL VCP ENST00000358901 human ensembl 74_37 -1 known frame_shift_del c.1847 p.N616fs 1 pfam_ATPase_AAA_core,superfamily_P-loop_NTPase,smart_AAA+_ATPase,tigrfam_AAA_ATPase_CDC48 pfam_ATPase_AAA_core,pfam_CDC4_N-term_subdom,pfam_DNA_helicase_Holl-junc_RuvB_N,pfam_Cdc48_dom2,pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-2,pfam_Vps4_C,superfamily_P-loop_NTPase,superfamily_Asp_de-COase-like_dom,smart_AAA+_ATPase,tigrfam_AAA_ATPase_CDC48 0 no_errors 0 0 0 29 0 0 26 10 27.78 160 0 0.00 117 41 25.95 LOC101927552 0 genome.wustl.edu 37 9 86482789 86482789 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 86482789 86482789 A 0 DEL LOC101927552 ENST00000421734 human ensembl 74_37 1 known rna NULL NULL 0.04 0 0 0 no_errors 0 0 0 63 0 0 42 16 27.59 143 1 0.69 143 60 29.56 IARS 0 genome.wustl.edu 37 9 95049772 95049773 + RNA INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 95049772 95049773 0 A INS IARS ENST00000490438 human ensembl 74_37 -1 known rna NULL NULL 0.573:0.411 0 0 0 no_errors 0 0 0 118 1 0.84 64 18 21.95 144 0 0.00 139 29 17.26 ENSG00000242111 0 genome.wustl.edu 37 9 107038701 107038701 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 107038701 107038701 A 0 DEL ENSG00000242111 ENST00000493279 human ensembl 74_37 1 known rna NULL NULL 0.001 0 0 0 no_errors 0 0 0 24 0 0 8 4 33.33 141 0 0.00 109 37 25.34 FAM206A 0 genome.wustl.edu 37 9 111696742 111696742 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 111696742 111696742 G 0 DEL FAM206A ENST00000466200 human ensembl 74_37 1 known rna NULL NULL 0.001 0 0 0 no_errors rs374390367 CG->C 0 46 0 0 28 19 40.43 11 0 0.00 12 5 29.41 OR2K2 0 genome.wustl.edu 37 9 114089908 114089909 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 114089908 114089909 0 T INS OR2K2 ENST00000374428 human ensembl 74_37 -1 known frame_shift_ins c.893_892 p.I298fs 0.052:0.001 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 91 0 0 62 30 32.61 213 0 0.00 233 67 22.33 FAM78A 0 genome.wustl.edu 37 9 134133531 134133531 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 134133531 134133531 G 0 DEL FAM78A ENST00000247295 human ensembl 74_37 -1 known rna NULL NULL 0.003 0 0 0 no_errors 0 0 0 32 0 0 14 8 36.36 161 0 0.00 142 34 19.32 NOTCH1 0 genome.wustl.edu 37 9 139407932 139407934 + In_Frame_Del DEL ATT ATT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 ATT ATT ATT - ATT ATT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139407932 139407934 ATT 0 DEL NOTCH1 ENST00000277541 human ensembl 74_37 -1 known in_frame_del c.2265_2263 p.N755in_frame_del 0.954:0.999:1.000 smart_EGF-like_Ca-bd_dom,pirsf_Notch,pfscan_EG-like_dom pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,pfam_Ankyrin_rpt,pfam_EGF_extracell,pfam_Notch_NOD_dom,pfam_DUF3454_notch,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,pirsf_Notch,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom,prints_Notch_1,prints_Notch_dom 0 no_errors rs587778559 CATT->C 0 11 0 0 5 4 44.44 205 0 0.00 139 55 28.35 KIAA1984 0 genome.wustl.edu 37 9 139699024 139699026 + In_Frame_Del DEL AGA AGA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AGA AGA AGA - AGA AGA Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 139699024 139699026 AGA 0 DEL KIAA1984 ENST00000338005 human ensembl 74_37 1 known in_frame_del c.737_739 p.K248in_frame_del 1.000:1.000:1.000 NULL NULL 0 no_errors 0 0 0 30 0 0 15 8 34.78 75 0 0.00 60 21 25.93 C10orf126 0 genome.wustl.edu 37 10 29169288 29169288 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 29169288 29169288 A 0 DEL C10orf126 ENST00000375520 human ensembl 74_37 1 known frame_shift_del c.432 p.A147fs 0 NULL NULL 0 no_errors 0 0 0 80 0 0 40 31 43.66 251 2 0.79 207 77 27.11 ZSWIM8 0 genome.wustl.edu 37 10 75560546 75560547 + RNA DEL CC CC - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 CC CC CC - CC CC Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 75560546 75560547 CC 0 DEL ZSWIM8 ENST00000603195 human ensembl 74_37 1 known rna NULL NULL 0.749:0.797 0 0 0 no_errors 0 0 0 74 0 0 55 27 32.93 151 0 0.00 131 49 27.22 ZDHHC16 0 genome.wustl.edu 37 10 99215505 99215507 + In_Frame_Del DEL AAG AAG - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AAG AAG AAG - AAG AAG Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 99215505 99215507 AAG 0 DEL ZDHHC16 ENST00000370854 human ensembl 74_37 1 known in_frame_del c.913_915 p.K306in_frame_del 1.000:0.988:0.995 NULL pfam_Znf_DHHC_palmitoyltrfase,pfscan_Znf_DHHC_palmitoyltrfase 0 no_errors 0 0 0 45 0 0 20 9 31.03 119 0 0.00 99 23 18.85 FAM178A 0 genome.wustl.edu 37 10 102690753 102690753 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 102690753 102690753 T 0 DEL FAM178A ENST00000370269 human ensembl 74_37 1 known frame_shift_del c.2354 p.L787fs 1 NULL NULL 0 no_errors 0 0 0 93 0 0 57 21 26.92 286 0 0.00 232 108 31.76 PDZD7 0 genome.wustl.edu 37 10 102789810 102789811 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 102789810 102789811 0 G INS PDZD7 ENST00000370215 human ensembl 74_37 -1 known frame_shift_ins c.167_166 p.R56fs 0.996:0.998 superfamily_PDZ pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ 0 no_errors 0 0 0 153 0 0 82 26 24.07 113 0 0.00 125 22 14.97 COL17A1 0 genome.wustl.edu 37 10 105819448 105819448 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 105819448 105819448 T 0 DEL COL17A1 ENST00000353479 human ensembl 74_37 -1 known frame_shift_del c.1170 p.E391fs 0.999 NULL pfam_Collagen 0 no_errors 0 0 0 90 0 0 50 21 29.58 226 0 0.00 222 82 26.97 XPNPEP1 0 genome.wustl.edu 37 10 111630571 111630572 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 111630571 111630572 0 A INS XPNPEP1 ENST00000502935 human ensembl 74_37 -1 known frame_shift_ins c.1614_1613 p.L538fs 1.000:1.000 pfam_Pept_M24_structural-domain,superfamily_Pept_M24_structural-domain pfam_Pept_M24_structural-domain,pfam_Creatinase,superfamily_Pept_M24_structural-domain 0 no_errors 0 0 0 39 0 0 24 6 20 155 0 0.00 178 56 23.93 ADD3 0 genome.wustl.edu 37 10 111893350 111893350 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 111893350 111893350 A 0 DEL ADD3 ENST00000356080 human ensembl 74_37 1 known frame_shift_del c.2095 p.K701fs 1 NULL pfam_Aldolase_II/adducin_N,superfamily_Aldolase_II/adducin_N 0 no_errors 0 0 0 82 0 0 49 15 23.44 214 2 0.93 209 59 22.01 KIAA1598 0 genome.wustl.edu 37 10 118719757 118719757 + RNA DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 118719757 118719757 A 0 DEL KIAA1598 ENST00000490615 human ensembl 74_37 -1 known rna NULL NULL 0 0 0 0 no_errors 0 0 0 26 0 0 21 4 16 234 1 0.43 204 71 25.82 PDZD8 0 genome.wustl.edu 37 10 119100598 119100598 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 10 119100598 119100598 A 0 DEL PDZD8 ENST00000334464 human ensembl 74_37 -1 known frame_shift_del c.888 p.P297fs 0.998 NULL pfam_PDZ,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_PDZ,smart_PDZ,smart_Prot_Kinase_C-like_PE/DAG-bd,pfscan_PDZ,pfscan_Prot_Kinase_C-like_PE/DAG-bd 0 no_errors 0 0 0 170 0 0 83 29 25.89 265 0 0.00 243 70 22.36 OR51E1 0 genome.wustl.edu 37 11 4674217 4674217 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 4674217 4674217 G 0 DEL OR51E1 ENST00000396952 human ensembl 74_37 1 known frame_shift_del c.461 p.A156fs 0.966 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 26 0 0 15 5 25 103 0 0.00 103 38 26.95 TRIM66 0 genome.wustl.edu 37 11 8662084 8662084 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 8662084 8662084 G 0 DEL TRIM66 ENST00000299550 human ensembl 74_37 -1 known frame_shift_del c.1403 p.P468fs 0.043 NULL pfam_Bromodomain,pfam_Znf_B-box,pfam_Znf_PHD-finger,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,smart_Znf_B-box,smart_Znf_PHD,smart_Bbox_C,smart_Bromodomain,pfscan_Znf_B-box,pfscan_Znf_PHD-finger,pfscan_Bromodomain 0 no_errors 0 0 0 26 0 0 21 7 25 19 0 0.00 19 3 13.64 MRGPRX3 0 genome.wustl.edu 37 11 18159303 18159303 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 18159303 18159303 T 0 DEL MRGPRX3 ENST00000396275 human ensembl 74_37 1 known frame_shift_del c.554 p.L187fs 0.006 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn 0 no_errors 0 0 0 86 0 0 45 17 27.42 96 0 0.00 69 30 30.30 SPTY2D1 0 genome.wustl.edu 37 11 18636367 18636367 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 18636367 18636367 G 0 DEL SPTY2D1 ENST00000336349 human ensembl 74_37 -1 known frame_shift_del c.1454 p.P485fs 0 NULL pfam_Chromatin_SPT2,smart_Chromatin_SPT2 0 no_errors 0 0 0 62 0 0 35 13 27.08 101 0 0.00 70 19 21.35 ANO5 0 genome.wustl.edu 37 11 22301099 22301099 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 22301099 22301099 T 0 DEL ANO5 ENST00000324559 human ensembl 74_37 1 known frame_shift_del c.2530 p.L845fs 0.998 pfam_Anoctamin pfam_Anoctamin 0 no_errors 0 0 0 38 0 0 27 18 40 276 0 0.00 215 107 33.23 MUC15 0 genome.wustl.edu 37 11 26587427 26587427 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 26587427 26587427 T 0 DEL MUC15 ENST00000436318 human ensembl 74_37 -1 known frame_shift_del c.60 p.K20fs 0 NULL NULL 0 no_errors 0 0 0 48 1 2.04 27 12 30.77 303 0 0.00 261 94 26.48 WT1-AS 0 genome.wustl.edu 37 11 32461025 32461026 + RNA INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 32461025 32461026 0 G INS WT1-AS ENST00000395900 human ensembl 74_37 1 known rna NULL NULL 0.000:0.000 0 0 0 no_errors 0 0 0 30 0 0 19 9 32.14 176 1 0.56 143 31 17.82 BEST1 0 genome.wustl.edu 37 11 61730428 61730429 + Frame_Shift_Del DEL CT CT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 CT CT CT - CT CT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 61730428 61730429 CT 0 DEL BEST1 ENST00000449131 human ensembl 74_37 1 known frame_shift_del c.1622_1623 p.L542fs 0.001:0.000 NULL pfam_Bestrophin/UPF0187 0 no_errors 0 0 0 46 0 0 18 10 35.71 154 0 0.00 152 46 23.23 ENSG00000256341 0 genome.wustl.edu 37 11 63886067 63886069 + RNA DEL TTT TTT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TTT TTT TTT - TTT TTT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 63886067 63886069 TTT 0 DEL ENSG00000256341 ENST00000543817 human ensembl 74_37 -1 known rna NULL NULL 0.001:0.000:0.000 0 0 0 no_errors 0 0 0 124 0 0 62 35 36.08 122 1 0.81 104 44 29.73 NRXN2 0 genome.wustl.edu 37 11 64457919 64457919 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 64457919 64457919 C 0 DEL NRXN2 ENST00000265459 human ensembl 74_37 -1 known frame_shift_del c.808 p.A270fs 1 NULL pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_EG-like_dom,smart_Neurexin-like,pfscan_EG-like_dom,pfscan_Laminin_G 0 no_errors 0 0 0 150 0 0 98 35 26.32 156 1 0.64 122 42 25.61 TRIM77 0 genome.wustl.edu 37 11 89444611 89444611 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 89444611 89444611 A 0 DEL TRIM77 ENST00000398290 human ensembl 74_37 1 known frame_shift_del c.445 p.K151fs 0.039 NULL pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin 0 no_errors 0 0 0 84 0 0 56 11 16.42 87 0 0.00 67 27 28.72 ENSG00000257057 0 genome.wustl.edu 37 11 94265163 94265164 + RNA INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 94265163 94265164 0 A INS ENSG00000257057 ENST00000542198 human ensembl 74_37 1 known rna NULL NULL 0.000:0.002 0 0 0 no_errors 0 0 0 110 0 0 32 10 23.81 288 2 0.69 247 86 25.83 NCAM1 0 genome.wustl.edu 37 11 113147558 113147558 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 113147558 113147558 G 0 DEL NCAM1 ENST00000397957 human ensembl 74_37 1 known rna NULL NULL 0.998 0 0 0 no_errors 0 0 0 74 0 0 52 16 23.53 118 0 0.00 110 37 25.17 BCL9L 0 genome.wustl.edu 37 11 118769235 118769236 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 118769235 118769236 0 G INS BCL9L ENST00000334801 human ensembl 74_37 -1 known frame_shift_ins c.4389_4388 p.P1464fs 0.036:0.989 NULL pfam_BCL9_beta-catenin-bd_dom 0 no_errors 0 0 0 30 0 0 13 7 35 13 0 0.00 17 2 10.53 SCNN1A 0 genome.wustl.edu 37 12 6457044 6457045 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 6457044 6457045 0 C INS SCNN1A ENST00000358945 human ensembl 74_37 -1 known frame_shift_ins c.2071_2070 p.P690fs 0.991:0.917 NULL pfam_Na+channel_ASC,prints_Na+channel_ASC,tigrfam_EnaC 0 no_errors 0 0 0 22 0 0 17 10 37.04 88 0 0.00 78 23 22.77 NOP2 0 genome.wustl.edu 37 12 6669943 6669943 + Frame_Shift_Del DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C C - C C Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 6669943 6669943 C 0 DEL NOP2 ENST00000322166 human ensembl 74_37 -1 known frame_shift_del c.1358 p.G453fs 1 pfam_Fmu/NOL1/Nop2p,pfam_rRNA_MeTrfase_FtsJ_dom,tigrfam_Nop2p pfam_Fmu/NOL1/Nop2p,pfam_P120R,pfam_rRNA_MeTrfase_FtsJ_dom,prints_RCMT,prints_RCMT_NOP2,tigrfam_Nop2p 0 no_errors 0 0 0 27 0 0 17 7 29.17 200 0 0.00 144 54 27.27 CD4 0 genome.wustl.edu 37 12 6927635 6927636 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 6927635 6927636 0 G INS CD4 ENST00000011653 human ensembl 74_37 1 known frame_shift_ins c.1205_1206 p.V405fs 0.034:0.049 NULL pfam_CD4-extracel,pfam_Ig_C2-set,pfam_Tcell_CD4_Cterm,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Ig_I-set,pfam_NK_rcpt_2B4_Ig_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom,prints_Ag_CD4 0 no_errors 0 0 0 25 0 0 19 7 26.92 64 0 0.00 54 19 26.03 TAS2R14 0 genome.wustl.edu 37 12 11091565 11091566 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 11091565 11091566 0 T INS TAS2R14 ENST00000537503 human ensembl 74_37 -1 known frame_shift_ins c.242_241 p.M81fs 0.000:0.000 pfam_TAS2_rcpt pfam_TAS2_rcpt 0 no_errors 0 0 0 104 0 0 57 26 31.33 261 0 0.00 218 69 24.04 ABCC9 0 genome.wustl.edu 37 12 21997479 21997480 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 21997479 21997480 0 A INS ABCC9 ENST00000261200 human ensembl 74_37 -1 known frame_shift_ins c.3253_3252 p.D1084fs 1.000:1.000 pfam_ABC_transptr_TM_dom,superfamily_ABC1_TM_dom,pfscan_ABC1_TM_dom pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_P-loop_NTPase,superfamily_ABC1_TM_dom,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom,prints_Sulphorea_rcpt,prints_Sulphonylurea_rcpt-2 0 no_errors 0 0 0 81 0 0 72 18 20 152 0 0.00 142 60 29.70 MUC19 0 genome.wustl.edu 37 12 40840397 40840397 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 40840397 40840397 G 0 DEL MUC19 ENST00000454784 human ensembl 74_37 1 novel frame_shift_del c.3091 p.G1032fs 1 NULL pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,smart_VWC_out,smart_VWF_type-D,smart_Unchr_dom_Cys-rich 0 no_errors 0 0 0 83 1 1.19 56 28 33.33 156 0 0.00 134 39 22.54 ZNF385A 0 genome.wustl.edu 37 12 54763757 54763757 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 54763757 54763757 G 0 DEL ZNF385A ENST00000552382 human ensembl 74_37 -1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 71 1 1.39 39 10 20.41 34 0 0.00 28 5 15.15 MMP19 0 genome.wustl.edu 37 12 56230905 56230905 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 56230905 56230905 G 0 DEL MMP19 ENST00000322569 human ensembl 74_37 -1 known frame_shift_del c.1442 p.P481fs 0 NULL pfam_Pept_M10_metallopeptidase,pfam_Hemopexin-like_repeat,pfam_Peptidoglycan-bd-like,superfamily_Hemopexin-like_dom,superfamily_Peptidoglycan-bd-like,smart_Peptidase_Metallo,smart_Hemopexin-like_repeat,pirsf_Pept_M10A_Metazoans,prints_Pept_M10A 0 no_errors 0 0 0 40 0 0 31 10 24.39 239 0 0.00 160 96 37.50 XPOT 0 genome.wustl.edu 37 12 64812755 64812755 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 64812755 64812755 T 0 DEL XPOT ENST00000332707 human ensembl 74_37 1 known frame_shift_del c.370 p.F126fs 1 pfam_Exportin-1/Importin-b-like,superfamily_ARM-type_fold pfam_Exportin-1/Importin-b-like,pfam_Importin-beta_N,superfamily_ARM-type_fold,smart_Importin-beta_N 0 no_errors 0 0 0 120 0 0 61 28 31.46 158 1 0.63 115 50 30.30 LRRIQ1 0 genome.wustl.edu 37 12 85449668 85449668 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 85449668 85449668 A 0 DEL LRRIQ1 ENST00000393217 human ensembl 74_37 1 known frame_shift_del c.1097 p.K368fs 0.92 NULL pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_IQ_motif_EF-hand-BS,smart_Leu-rich_rpt_typical-subtyp,pfscan_IQ_motif_EF-hand-BS 0 no_errors 0 0 0 131 0 0 66 34 34 107 0 0.00 95 33 25.78 UHRF1BP1L 0 genome.wustl.edu 37 12 100441791 100441791 + Frame_Shift_Del DEL A A - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A A - A A Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 12 100441791 100441791 A 0 DEL UHRF1BP1L ENST00000279907 human ensembl 74_37 -1 known frame_shift_del c.3902 p.L1301fs 1 NULL NULL 0 no_errors 0 0 0 96 0 0 70 19 21.35 226 0 0.00 169 65 27.78 WASF3 0 genome.wustl.edu 37 13 27255386 27255387 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 27255386 27255387 0 C INS WASF3 ENST00000335327 human ensembl 74_37 1 known frame_shift_ins c.912_913 p.P307fs 0.439:0.975 NULL pfam_WH2_dom,smart_WH2_dom,pfscan_WH2_dom 0 no_errors 0 0 0 28 0 0 11 16 59.26 27 0 0.00 25 15 37.50 LRRC63 0 genome.wustl.edu 37 13 46840907 46840907 + Frame_Shift_Del DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T T - T T Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 46840907 46840907 T 0 DEL LRRC63 ENST00000446175 human ensembl 74_37 1 known frame_shift_del c.1350 p.F452fs 0 smart_Leu-rich_rpt_typical-subtyp pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp 0 no_errors 0 0 0 121 0 0 67 28 29.47 274 0 0.00 248 75 23.22 INTS6 0 genome.wustl.edu 37 13 51969467 51969468 + Frame_Shift_Del DEL AG AG - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 AG AG AG - AG AG Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 51969467 51969468 AG 0 DEL INTS6 ENST00000311234 human ensembl 74_37 -1 known frame_shift_del c.582_581 p.S194fs 1.000:1.000 pfscan_VWF_A pfam_VWF_A,pfscan_VWF_A 0 no_errors 0 0 0 91 0 0 49 18 26.87 76 0 0.00 74 26 26.00 RNF219-AS1 0 genome.wustl.edu 37 13 79154451 79154454 + RNA DEL TCTT TCTT - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TCTT TCTT TCTT - TCTT TCTT Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 79154451 79154454 TCTT 0 DEL RNF219-AS1 ENST00000607862 human ensembl 74_37 1 known rna NULL NULL 0.004:0.004:0.004:0.005 0 0 0 no_errors 0 0 0 11 0 0 4 2 33.33 217 0 0.00 202 63 23.77 SLITRK6 0 genome.wustl.edu 37 13 86368997 86368997 + Frame_Shift_Del DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G G - G G Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 13 86368997 86368997 G 0 DEL SLITRK6 ENST00000400286 human ensembl 74_37 -1 known frame_shift_del c.1647 p.H551fs 0.771 smart_Cys-rich_flank_reg_C pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C 0 no_errors 0 0 0 32 0 0 13 5 27.78 195 0 0.00 183 35 16.06 ARHGAP5 0 genome.wustl.edu 37 14 32562695 32562696 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 32562695 32562696 0 A INS ARHGAP5 ENST00000345122 human ensembl 74_37 1 known frame_shift_ins c.2820_2821 p.N942fs 1.000:1.000 NULL pfam_RhoGAP_dom,pfam_FF_domain,pfam_Small_GTPase,superfamily_Rho_GTPase_activation_prot,superfamily_P-loop_NTPase,superfamily_FF_domain,smart_FF_domain,smart_RhoGAP_dom,pfscan_RhoGAP_dom,prints_Small_GTPase 0 no_errors 0 0 0 106 0 0 55 25 31.25 81 0 0.00 89 22 19.82 SLC25A47 0 genome.wustl.edu 37 14 100795092 100795093 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 100795092 100795093 0 A INS SLC25A47 ENST00000361529 human ensembl 74_37 1 known frame_shift_ins c.357_358 p.V120fs 1.000:1.000 pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_carrier pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_carrier 0 no_errors 0 0 0 42 0 0 18 7 28 38 0 0.00 27 18 40.00 CEP170B 0 genome.wustl.edu 37 14 105353222 105353223 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 14 105353222 105353223 0 C INS CEP170B ENST00000453495 human ensembl 74_37 1 known frame_shift_ins c.2649_2650 p.H885fs 0.910:0.969 NULL pfam_FHA_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,pfscan_FHA_dom 0 no_errors 0 0 0 52 0 0 37 19 33.93 113 0 0.00 83 30 26.55 IRX3 0 genome.wustl.edu 37 16 54319086 54319087 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 54319086 54319087 0 C INS IRX3 ENST00000329734 human ensembl 74_37 -1 known frame_shift_ins c.707_706 p.E236fs 1.000:1.000 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,smart_Iroquois_homeo,pfscan_Homeobox_dom 0 no_errors 0 0 0 20 0 0 5 5 50 125 0 0.00 48 29 37.66 E2F4 0 genome.wustl.edu 37 16 67229793 67229794 + In_Frame_Ins INS - - CAG TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - CAG - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 67229793 67229794 0 CAG INS E2F4 ENST00000379378 human ensembl 74_37 1 known in_frame_ins c.917_918 p.310in_frame_insS 1.000:0.995 NULL pfam_E2F_TDP 0 no_errors 0 0 0 46 0 0 19 3 13.64 31 0 0.00 15 4 21.05 PELP1 0 genome.wustl.edu 37 17 4576011 4576012 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 4576011 4576012 0 C INS PELP1 ENST00000301396 human ensembl 74_37 -1 known frame_shift_ins c.2707_2706 p.R902fs 0.905:0.913 NULL pfam_Uncharacterised_NUC202,superfamily_ARM-type_fold 0 no_errors 0 0 0 44 0 0 26 17 39.53 95 0 0.00 91 32 26.02 UBB 0 genome.wustl.edu 37 17 16285784 16285785 + Frame_Shift_Ins INS - - C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - C - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 16285784 16285785 0 C INS UBB ENST00000302182 human ensembl 74_37 1 novel frame_shift_ins c.563_564 p.D191fs 1.000:0.986 pfam_Ubiquitin_dom,pfam_Rad60/SUMO_like,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup pfam_Ubiquitin_dom,pfam_Rad60/SUMO_like,smart_Ubiquitin_dom,prints_Ubiquitin,pfscan_Ubiquitin_supergroup 0 no_errors 0 0 0 77 0 0 49 18 26.87 57 0 0.00 39 18 31.58 GPATCH8 0 genome.wustl.edu 37 17 42483347 42483348 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 42483347 42483348 0 T INS GPATCH8 ENST00000591680 human ensembl 74_37 -1 known frame_shift_ins c.565_564 p.Q188fs 1.000:1.000 NULL pfam_G_patch_dom,pfam_Znf_C2H2_jaz,smart_G_patch_dom,pfscan_Znf_C2H2,pfscan_G_patch_dom 0 no_errors 0 0 0 68 0 0 55 19 25.68 217 0 0.00 175 62 26.16 TANC2 0 genome.wustl.edu 37 17 61482503 61482504 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 17 61482503 61482504 0 G INS TANC2 ENST00000424789 human ensembl 74_37 1 known frame_shift_ins c.3130_3131 p.K1046fs 1.000:1.000 pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,smart_Ankyrin_rpt,smart_TPR_repeat,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_TPR_repeat,pfscan_TPR-contain_dom,prints_Ankyrin_rpt 0 no_errors 0 0 0 42 0 0 18 4 18.18 177 0 0.00 146 54 27.00 ANKRD12 0 genome.wustl.edu 37 18 9256772 9256773 + Frame_Shift_Ins INS - - A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - A - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 18 9256772 9256773 0 A INS ANKRD12 ENST00000262126 human ensembl 74_37 1 known frame_shift_ins c.3507_3508 p.N1170fs 0.998:1.000 NULL pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt 0 no_errors 0 0 0 47 0 0 46 13 22.03 211 0 0.00 230 48 17.27 FAM83E 0 genome.wustl.edu 37 19 49107037 49107038 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 19 49107037 49107038 0 G INS FAM83E ENST00000263266 human ensembl 74_37 -1 known frame_shift_ins c.890_889 p.Q297fs 0.000:0.001 NULL pfam_DUF1669,superfamily_Acyl_CoA_acyltransferase 0 no_errors 0 0 0 46 0 0 30 4 11.76 28 0 0.00 39 5 11.36 CSRP2BP 0 genome.wustl.edu 37 20 18125916 18125917 + Frame_Shift_Ins INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - T - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 18125916 18125917 0 T INS CSRP2BP ENST00000435364 human ensembl 74_37 1 known frame_shift_ins c.299_300 p.R103fs 1.000:1.000 NULL pfam_GNAT_dom,superfamily_Acyl_CoA_acyltransferase,pfscan_GNAT_dom 0 no_errors 0 0 0 41 0 0 31 16 34.04 170 0 0.00 147 46 23.83 RBBP8NL 0 genome.wustl.edu 37 20 60990955 60990956 + Frame_Shift_Ins INS - - G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - - G - - Unknown Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 60990955 60990956 0 G INS RBBP8NL ENST00000252998 human ensembl 74_37 -1 known frame_shift_ins c.433_432 p.S144fs 0.246:0.005 NULL pfam_CtIP_N 0 no_errors 0 0 0 13 0 0 16 3 15.79 19 0 0.00 12 4 25.00 ESX1 0 genome.wustl.edu 37 X 103495107 103495107 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 103495107 103495107 G A SNP ESX1 ENST00000372588 human ensembl 74_37 -1 known silent c.1023 p.P341 0 NULL pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_POU 0 no_errors 0 0 0 17 0 0 17 3 15 9 0 0.00 6 0 0.00 GPR153 0 genome.wustl.edu 37 1 6314015 6314015 + Silent SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 6314015 6314015 G A SNP GPR153 ENST00000377893 human ensembl 74_37 -1 known silent c.549 p.S183 0.863 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GCR_153/162 pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPR153,prints_GCR_153/162 0 no_errors 0 0 0 35 0 0 33 5 13.16 9 0 0.00 10 0 0.00 ENSG00000221447 0 genome.wustl.edu 37 1 48086784 48086784 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 48086784 48086784 T C SNP ENSG00000221447 ENST00000408520 human ensembl 74_37 -1 novel rna NULL NULL 0.004 0 0 0 no_errors 0 0 0 34 0 0 21 6 22.22 0 0 0.00 1 0 0.00 NBPF14 0 genome.wustl.edu 37 1 148004583 148004583 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 148004583 148004583 G T SNP NBPF14 ENST00000369219 human ensembl 74_37 -1 known missense c.2731 p.L911M 0.001 NULL pfam_NBPF_dom 0 no_errors 0 0 0 317 0 0 268 23 7.9 0 0 0.00 0 0 0.00 ENSG00000221234 0 genome.wustl.edu 37 2 166670786 166670786 + RNA SNP A A G TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 A A Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 166670786 166670786 A G SNP ENSG00000221234 ENST00000408307 human ensembl 74_37 1 novel rna NULL NULL 0.002 0 0 0 no_errors 0 0 0 74 0 0 46 21 31.34 0 0 0.00 0 0 0.00 UGT2B10 0 genome.wustl.edu 37 4 69688085 69688085 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 4 69688085 69688085 G A SNP UGT2B10 ENST00000265403 human ensembl 74_37 1 known missense c.964 p.V322I 0.013 pfam_UDP_glucos_trans pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C 0 no_errors rs369643682 G->A 0 270 1 0.37 144 54 27.27 0 0 0.00 0 0 0.00 PCDHA7 0 genome.wustl.edu 37 5 140215417 140215417 + Silent SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 5 140215417 140215417 C T SNP PCDHA7 ENST00000525929 human ensembl 74_37 1 known silent c.1449 p.D483 0.123 pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin 0 no_errors 0 0 0 104 0 0 69 19 21.35 9 0 0.00 5 0 0.00 ACTB 0 genome.wustl.edu 37 7 5566946 5566946 + RNA SNP C C A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 7 5566946 5566946 C A SNP ACTB ENST00000464611 human ensembl 74_37 -1 known rna NULL NULL 0.251 0 0 0 no_errors rs3206243 C->A 0 58 0 0 34 5 12.82 5 0 0.00 8 0 0.00 ANKRD20A4 0 genome.wustl.edu 37 9 69391189 69391189 + Nonsense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 69391189 69391189 C T SNP ANKRD20A4 ENST00000357336 human ensembl 74_37 1 known nonsense c.697 p.R233* 0.009 superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt 0 no_errors 0 0 0 85 0 0 56 11 16.42 0 0 0.00 0 0 0.00 TUBBP5 0 genome.wustl.edu 37 9 141069844 141069844 + RNA SNP T T C TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 9 141069844 141069844 T C SNP TUBBP5 ENST00000290377 human ensembl 74_37 1 known rna NULL NULL 0.991 0 0 0 no_errors rs62581042 T->C 0 40 1 2.44 21 6 22.22 4 0 0.00 2 0 0.00 DDX11L10 0 genome.wustl.edu 37 16 62353 62353 + RNA SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 62353 62353 C T SNP DDX11L10 ENST00000513886 human ensembl 74_37 1 known rna NULL NULL 1 0 0 0 no_errors 0 0 0 28 0 0 8 8 50 0 0 0.00 0 0 0.00 PKD1 0 genome.wustl.edu 37 16 2168302 2168302 + Missense_Mutation SNP G G T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 2168302 2168302 G T SNP PKD1 ENST00000262304 human ensembl 74_37 -1 known missense c.691 p.L231M 0.966 pfam_WSC_carb-bd,smart_WSC_carb-bd_subgr,pfscan_WSC_carb-bd,tigrfam_Polycystin_cat pfam_PKD_dom,pfam_PKD1_2_channel,pfam_PKD/REJ-like,pfam_PLAT/LH2_dom,pfam_C-type_lectin,pfam_WSC_carb-bd,pfam_GPS_dom,superfamily_C-type_lectin_fold,superfamily_Lipase_LipOase,superfamily_PKD_dom,superfamily_Fe_hydrogenase,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_WSC_carb-bd_subgr,smart_PKD/Chitinase_dom,smart_C-type_lectin,smart_GPS_dom,smart_PLAT/LH2_dom,prints_PKD_1,pfscan_GPS_dom,pfscan_C-type_lectin,pfscan_PKD_dom,pfscan_PLAT/LH2_dom,pfscan_REJ-like,pfscan_WSC_carb-bd,tigrfam_Polycystin_cat 0 no_errors 0 0 0 27 0 0 14 6 30 0 0 0.00 0 0 0.00 NPIPA5 0 genome.wustl.edu 37 16 15457863 15457863 + Missense_Mutation SNP C C T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 16 15457863 15457863 C T SNP NPIPA5 ENST00000360151 human ensembl 74_37 -1 novel missense c.706 p.A236T 0.007 NULL NULL 0 no_errors 0 0 0 94 0 0 63 5 7.35 0 0 0.00 0 0 0.00 FOXA2 0 genome.wustl.edu 37 20 22562846 22562846 + Missense_Mutation SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 22562846 22562846 G A SNP FOXA2 ENST00000419308 human ensembl 74_37 -1 known missense c.1034 p.P345L 1 NULL pfam_TF_fork_head,pfam_Fork-head_N,pfam_Forkhead_box_C,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head 0 no_errors 0 0 0 19 0 0 12 4 25 14 0 0.00 2 0 0.00 ENSG00000238129 0 genome.wustl.edu 37 20 26174050 26174050 + RNA SNP G G A TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 20 26174050 26174050 G A SNP ENSG00000238129 ENST00000416638 human ensembl 74_37 1 known rna NULL NULL 0.332 0 0 0 no_errors 0 0 0 98 0 0 72 32 30.77 1 0 0.00 0 0 0.00 MIR548AN 0 genome.wustl.edu 37 X 105883110 105883110 + RNA DEL T T - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 T T Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 X 105883110 105883110 T 0 DEL MIR548AN ENST00000408286 human ensembl 74_37 1 known rna NULL NULL 0.046 0 0 0 no_errors 0 0 0 78 0 0 39 14 26.42 0 0 0.00 0 0 0.00 ENSG00000221664 0 genome.wustl.edu 37 1 77857130 77857131 + RNA INS - - TATG TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 77857130 77857131 0 TATG INS ENSG00000221664 ENST00000408737 human ensembl 74_37 -1 novel rna NULL NULL 0.997:0.995 0 0 0 no_errors 0 0 0 42 0 0 30 5 14.29 0 0 0.00 0 0 0.00 ENSG00000231512 0 genome.wustl.edu 37 1 243202371 243202371 + RNA DEL C C - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 C C Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 1 243202371 243202371 C 0 DEL ENSG00000231512 ENST00000450226 human ensembl 74_37 -1 known rna NULL NULL 0.082 0 0 0 no_errors rs371012782 AC->A 0 21 0 0 17 9 34.62 0 0 0.00 0 0 0.00 ANKRD20A8P 0 genome.wustl.edu 37 2 95483038 95483039 + RNA INS - - T TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 - - Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 95483038 95483039 0 T INS ANKRD20A8P ENST00000432432 human ensembl 74_37 -1 known rna NULL NULL 0.185:0.232 0 0 0 no_errors 0 0 0 212 0 0 109 51 31.87 0 0 0.00 0 0 0.00 KLF7 0 genome.wustl.edu 37 2 207945782 207945783 + RNA DEL TA TA - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TA TA Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 2 207945782 207945783 TA 0 DEL KLF7 ENST00000467833 human ensembl 74_37 -1 putative rna NULL NULL 0.958:0.994 0 0 0 no_errors 0 0 0 34 1 2.86 23 9 28.12 0 0 0.00 0 0 0.00 KIAA2018 0 genome.wustl.edu 37 3 113376111 113376119 + In_Frame_Del DEL TGCTGCTGC TGCTGCTGC - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 TGCTGCTGC TGCTGCTGC Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 3 113376111 113376119 TGCTGCTGC 0 DEL KIAA2018 ENST00000316407 human ensembl 74_37 -1 known in_frame_del c.4418_4410 p.QQQ1474in_frame_del 0.994:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000 NULL pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom 0 no_errors rs112313093 TTGCTGCTGC->T 0 17 1 5.56 17 7 29.17 2 0 0.00 3 0 0.00 LOC100287896 0 genome.wustl.edu 37 11 74208224 74208224 + RNA DEL G G - TCGA-ZB-A966-01A-11D-A428-09 TCGA-ZB-A966-10A-01D-A42B-09 G G Unknown Untested Somatic Phase_IV WXS none Illumina HiSeq 644f7f62-e6f1-41e7-a00f-805a9068c9c6 4cfff548-ed75-490e-96f8-6ff3f41ce9d5 11 74208224 74208224 G 0 DEL LOC100287896 ENST00000526036 human ensembl 74_37 1 known rna NULL NULL 0.254 0 0 0 no_errors 0 0 0 50 0 0 16 2 11.11 0 0 0.00 0 0 0.00