Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain ARID1A 8289 genome.wustl.edu 37 1 27106168 27106169 + Frame_Shift_Ins INS - - CT novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_006015.4 +1 reviewed p.K1928fs 0.008:0.672 - - - - - - - - - NULL ARID1A 8289 genome.wustl.edu 37 1 27107105 27107105 + Missense_Mutation SNP T T C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_006015.4 +1 reviewed p.L2239P 0.998 57 0% 47 29.8% 42 42.8% probably_damaging(0.997) tolerated(0.11) deleterious(0.738) NULL BCL9 607 genome.wustl.edu 37 1 147096117 147096117 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_004326.2 +1 reviewed p.S1213L 1.000 44 2.3% 43 25.6% 12 58.3% possibly_damaging(0.918) tolerated(0.06) deleterious(0.691) NULL ARHGEF11 9826 genome.wustl.edu 37 1 156949025 156949025 + Missense_Mutation SNP G G C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_198236.1 -1 reviewed p.I109M 1.000 326 0% 318 19.8% 4 25% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_PDZ,HMMSmart_PDZ,superfamily_PDZ PKP1 5317 genome.wustl.edu 37 1 201288983 201288983 + Silent SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000299.2 +1 reviewed p.P424 0.000 78 0% 90 30% 0 - - - - superfamily_ARM repeat GALNT14 79623 genome.wustl.edu 37 2 31133839 31133839 + Silent SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_024572.2 -1 validated p.N529 0.002 248 0.4% 207 26.1% 45 17.7% - - - HMMPfam_Ricin_B_lectin,HMMSmart_SM00458,superfamily_Ricin B-like lectins XIRP2 129446 genome.wustl.edu 37 2 168103963 168103963 + Missense_Mutation SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_152381.4 +1 validated p.A2021S 0.987 102 0% 60 25% 0 - possibly_damaging(0.737) deleterious(0) deleterious(0.714) NULL TTN 7273 genome.wustl.edu 37 2 179393347 179393347 + Nonsense_Mutation SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 ENST00000356127 -1 known p.Q33141* 1.000 291 0% 214 17.3% 0 - - - - HMMSmart_SM00409,HMMPfam_I-set TTN 7273 genome.wustl.edu 37 2 179478885 179478885 + Silent SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 ENST00000356127 -1 known p.T13845 1.000 490 0% 528 21.2% 11 45.4% - - - HMMPfam_fn3,HMMSmart_SM00060 CCDC150 284992 genome.wustl.edu 37 2 197530399 197530399 + Nonsense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001080539.1 +1 provisional p.R252* 1.000 218 0% 185 18.9% 0 - - - - NULL ALS2 57679 genome.wustl.edu 37 2 202572613 202572613 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_020919.3 -1 reviewed p.R1461Q 1.000 240 0.8% 239 22.2% 4 75% possibly_damaging(0.792) tolerated(0.56) neutral(0.303) superfamily_VPS9 domain (Pfam 02204) MFF 56947 genome.wustl.edu 37 2 228221828 228221828 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_020194.4 +1 provisional p.R342C 1.000 421 0% 409 13% 142 51.4% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_DUF800 NUP210 23225 genome.wustl.edu 37 3 13377058 13377058 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_024923.2 -1 reviewed p.V1247I 0.269 119 0% 118 23.7% 7 42.8% benign(0.111) tolerated(0.19) neutral(0.058) NULL PLXNA1 5361 genome.wustl.edu 37 3 126736462 126736462 + Silent SNP C C G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_032242.3 +1 validated p.P1134 0.998 105 0% 88 25% 2 50% - - - HMMPfam_TIG,HMMSmart_SM00429,superfamily_E set domains ANTXR2 118429 genome.wustl.edu 37 4 80898779 80898779 + Missense_Mutation SNP T T A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001145794.1 -1 reviewed p.D475V 1.000 326 0% 286 21.3% 3 100% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Ant_C SKIV2L2 23517 genome.wustl.edu 37 5 54635988 54635988 + Silent SNP A A G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_015360.4 +1 validated p.A222 1.000 430 0% 423 22.9% 2 50% - - - HMMPfam_DEAD,HMMSmart_DEXDc,superfamily_SSF52540 MAP3K1 4214 genome.wustl.edu 37 5 56161690 56161690 + Missense_Mutation SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_005921.1 +1 validated p.R396H 1.000 363 0% 288 14.9% 1 0% probably_damaging(0.998) deleterious(0) deleterious(0.919) NULL CYFIP2 26999 genome.wustl.edu 37 5 156817650 156817650 + Missense_Mutation SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001037332.2 +1 validated p.G1190W 1.000 218 0% 215 19.5% 10 0% probably_damaging(0.989) deleterious(0.01) deleterious(0.845) HMMPfam_FragX_IP SYNGAP1 8831 genome.wustl.edu 37 6 33399956 33399956 + Frame_Shift_Del DEL C C - novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_006772.2 +1 reviewed p.S105fs 1.000 - - - - - - - - - HMMSmart_SM00233 DSE 29940 genome.wustl.edu 37 6 116757323 116757323 + Silent SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001080976.1 +1 reviewed p.Q564 1.000 194 0% 145 19.3% 2 0% - - - NULL ESR1 2099 genome.wustl.edu 37 6 152382152 152382154 + In_Frame_Del DEL TGG TGG - novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 TGG TGG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000125.3 +1 reviewed p.V422in_frame_del 1.000:1.000:1.000 - - - - - - - - - HMMPfam_Hormone_recep,HMMSmart_SM00430,superfamily_Nuclear receptor ligand-binding domain NPSR1 387129 genome.wustl.edu 37 7 34724220 34724220 + Silent SNP C C G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_207173.1 +1 reviewed p.S68 0.000 580 0% 639 19.9% 0 - - - - HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like HIP1 3092 genome.wustl.edu 37 7 75189186 75189186 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_005338.4 -1 reviewed p.V409I 0.001 15 0% 21 23.8% 3 0% benign(0.001) tolerated(0.55) neutral(0.007) NULL TRRAP 8295 genome.wustl.edu 37 7 98609014 98609014 + Silent SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 ENST00000456197 +1 known p.R3446Q 0.001 137 0% 120 14.2% 27 40.7% - - - HMMSmart_SM00146,superfamily_Protein kinase-like (PK-like),superfamily_ARM repeat CNTNAP2 26047 genome.wustl.edu 37 7 147844678 147844678 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_014141.5 +1 reviewed p.R884W 1.000 159 0% 136 24.3% 0 - probably_damaging(1) tolerated(0.17) deleterious(0.559) HMMSmart_SM00282,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2 EZH2 2146 genome.wustl.edu 37 7 148514368 148514368 + Nonsense_Mutation SNP G G C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_004456.3 -1 reviewed p.Y452* 1.000 317 0% 304 25% 4 75% - - - HMMSmart_SANT SSPO 23145 genome.wustl.edu 37 7 149477454 149477454 + Nonsense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 ENST00000378016 +1 known p.R509* 0.000 60 0% 58 25.9% 0 - - - - superfamily_Serine proterase inhibitors,HMMPfam_TIL CSMD1 64478 genome.wustl.edu 37 8 3265577 3265577 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_033225.5 -1 validated p.A640T 0.073 232 0% 185 26.5% 0 - benign(0) tolerated(0.87) neutral(0.001) HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain HR 55806 genome.wustl.edu 37 8 21979148 21979148 + Missense_Mutation SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_005144.4 -1 reviewed p.H727Q 0.934 443 0.5% 483 23.6% 1 0% benign(0.017) tolerated(0.19) neutral(0.050) NULL FAM135B 51059 genome.wustl.edu 37 8 139190825 139190825 + Missense_Mutation SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_015912.3 -1 validated p.H328N 0.998 206 0% 209 18.2% 0 - benign(0.247) tolerated(0.34) neutral(0.048) NULL PCBD1 5092 genome.wustl.edu 37 10 72643772 72643772 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000281.2 -1 reviewed p.G84S 1.000 178 0% 157 42.7% 266 92.1% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_Pterin_4a,superfamily_Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) PTEN 5728 genome.wustl.edu 37 10 89717626 89717626 + Frame_Shift_Del DEL C C - novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 ENST00000371953 +1 known p.C218fs 1.000 - - - - - - - - - superfamily_C2 domain (Calcium/lipid-binding domain CaLB),HMMPfam_PTEN_C2 FGFR2 2263 genome.wustl.edu 37 10 123279677 123279677 + Missense_Mutation SNP G G C rs79184941 byCluster TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_022970.3 -1 reviewed p.S252W 1.000 117 0% 107 23.4% 5 60% probably_damaging(0.963) tolerated(0.07) deleterious(0.725) NULL STK32C 282974 genome.wustl.edu 37 10 134036465 134036465 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_173575.2 -1 reviewed p.R340Q 0.998 41 0% 47 12.8% 2 50% probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase MUC5B 727897 genome.wustl.edu 37 11 1268804 1268804 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_002458.1 +1 validated p.T3568M 0.001 295 0.3% 287 13.6% 20 40% unknown(0) - - NULL OR4A16 81327 genome.wustl.edu 37 11 55111246 55111246 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001005274.1 +1 provisional p.T190 0.718 589 0% 462 17.7% 0 - - - - HMMPfam_7tm_1,superfamily_SSF81321 PGR 5241 genome.wustl.edu 37 11 100933192 100933192 + Missense_Mutation SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000926.4 -1 reviewed p.S733Y 1.000 262 0% 254 16.9% 15 6.6% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Hormone_recep,HMMSmart_SM00430,superfamily_Nuclear receptor ligand-binding domain DYNC2H1 79659 genome.wustl.edu 37 11 102980397 102980397 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001080463.1 +1 reviewed p.L32 0.000 129 0% 152 19.7% 0 - - - - NULL OR8D2 283160 genome.wustl.edu 37 11 124189683 124189683 + Silent SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001002918.1 -1 provisional p.S137 0.001 177 0% 128 18.8% 0 - - - - HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like TAS2R13 50838 genome.wustl.edu 37 12 11061487 11061487 + Silent SNP G G C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_023920.2 -1 reviewed p.T137 0.000 198 0% 143 25.2% 0 - - - - HMMPfam_TAS2R,superfamily_SSF81321 CSAD 51380 genome.wustl.edu 37 12 53553926 53553926 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_015989.4 -1 validated p.D409N 0.897 65 1.5% 98 28.6% 33 42.4% benign(0.015) tolerated(0.64) neutral(0.004) HMMPfam_Pyridoxal_deC,superfamily_PLP-dependent transferases ARHGAP9 64333 genome.wustl.edu 37 12 57872934 57872934 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_032496.2 -1 reviewed p.E86K 0.976 260 0% 227 25.6% 0 - possibly_damaging(0.649) tolerated(0.1) deleterious(0.514) HMMSmart_SH3,superfamily_SH3 KCTD10 83892 genome.wustl.edu 37 12 109889536 109889536 + Missense_Mutation SNP T T C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_031954.3 -1 provisional p.N269S 1.000 50 0% 42 21.4% 9 0% benign(0.085) tolerated(0.88) neutral(0.006) NULL SDSL 113675 genome.wustl.edu 37 12 113871964 113871964 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_138432.2 +1 provisional p.A127V 1.000 147 0% 173 22% 21 42.8% probably_damaging(0.979) deleterious(0.03) deleterious(0.786) HMMPfam_PALP,superfamily_PyrdxlP-dep_enz_bsu OR4M1 441670 genome.wustl.edu 37 14 20249106 20249106 + Missense_Mutation SNP G G T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001005500.1 +1 provisional p.V209L 0.908 741 0.1% 769 19.9% 0 - benign(0.002) tolerated(0.83) neutral(0.001) HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like BDKRB2 624 genome.wustl.edu 37 14 96707048 96707048 + Missense_Mutation SNP C C T rs183386880 by1000genomes TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000623.3 +1 reviewed p.T128M 0.000 78 1.3% 74 27% 1 0% benign(0.253) tolerated(0.14) neutral(0.276) HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like SLC30A4 7782 genome.wustl.edu 37 15 45777386 45777386 + Missense_Mutation SNP G G C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_013309.4 -1 validated p.A422G 0.616 349 0% 352 19% 1 0% benign(0) tolerated(0.4) neutral(0.016) NULL ABAT 18 genome.wustl.edu 37 16 8858686 8858686 + Missense_Mutation SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000663.4 +1 reviewed p.R180Q 1.000 85 0% 86 22.1% 1 0% possibly_damaging(0.621) tolerated(0.41) neutral(0.231) HMMPfam_Aminotran_3,superfamily_PyrdxlP-dep_Trfase_major E2F4 1874 genome.wustl.edu 37 16 67231931 67231931 + Missense_Mutation SNP C C G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001950.3 +1 reviewed p.L383V 1.000 240 0% 257 18.7% 63 38% probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL MARVELD3 91862 genome.wustl.edu 37 16 71668441 71668441 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_052858.3 +1 validated p.A314V 0.128 153 0% 144 22.9% 4 25% possibly_damaging(0.902) deleterious(0.01) deleterious(0.762) HMMPfam_MARVEL ANKFN1 162282 genome.wustl.edu 37 17 54403675 54403675 + Silent SNP A A G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_153228.2 +1 validated p.L52 1.000 301 0% 278 23% 0 - - - - NULL CCDC47 57003 genome.wustl.edu 37 17 61843400 61843400 + Missense_Mutation SNP T T C novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_020198.2 -1 validated p.M46V 0.004 272 0.4% 261 19.5% 11 36.3% benign(0) tolerated(0.34) neutral(0.023) NULL ABCA8 10351 genome.wustl.edu 37 17 66881445 66881445 + Silent SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_007168.2 -1 reviewed p.F1107 0.001 203 0% 156 17.3% 0 - - - - NULL CTIF 9811 genome.wustl.edu 37 18 46146000 46146000 + Missense_Mutation SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001142397.1 +1 validated p.E22K 1.000 41 0% 36 11.1% 1 0% probably_damaging(0.998) deleterious(0) deleterious(0.919) NULL GNA11 2767 genome.wustl.edu 37 19 3113330 3113330 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_002067.2 +1 validated p.A108 1.000 41 0% 42 16.7% 7 42.8% - - - HMMPfam_G-alpha,superfamily_Transducn_insert,superfamily_SSF52540 CAMSAP3 57662 genome.wustl.edu 37 19 7682714 7682714 + Frame_Shift_Del DEL C C - novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001080429.2 +1 validated p.T1201fs 0.990 - - - - - - - - - superfamily_PRC-barrel domain,HMMPfam_DUF1781 FBN3 84467 genome.wustl.edu 37 19 8161815 8161815 + Missense_Mutation SNP C C A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_032447.3 -1 reviewed p.R1788L 1.000 77 1.3% 92 18.5% 0 - probably_damaging(0.996) deleterious(0.01) deleterious(0.867) PatternScan_ASX_HYDROXYL,HMMSmart_SM00179,HMMSmart_SM00181,HMMPfam_EGF_CA,PatternScan_EGF_CA,superfamily_EGF/Laminin MUC16 94025 genome.wustl.edu 37 19 9073176 9073176 + Missense_Mutation SNP G G A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_024690.2 -1 validated p.P4757L 0.003 184 0% 148 20.3% 3 66.6% unknown(0) - - NULL CYP4F2 8529 genome.wustl.edu 37 19 15989736 15989736 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001082.3 -1 reviewed p.G470R 1.000 87 0% 87 16.1% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_p450,superfamily_Cytochrome_P450,PatternScan_CYTOCHROME_P450 SLC5A5 6528 genome.wustl.edu 37 19 18001755 18001755 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_000453.2 +1 reviewed p.T571I 0.219 113 0% 157 23.6% 1 100% possibly_damaging(0.923) deleterious(0.02) deleterious(0.756) NULL IL12RB1 3594 genome.wustl.edu 37 19 18174729 18174729 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_005535.1 -1 reviewed p.A525 0.000 32 0% 47 17% 2 0% - - - HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III ZNF606 80095 genome.wustl.edu 37 19 58490830 58490830 + Silent SNP C C A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_025027.3 -1 validated p.G406 0.002 242 0% 188 20.2% 4 0% - - - HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers PROKR2 128674 genome.wustl.edu 37 20 5294673 5294673 + Missense_Mutation SNP C C T rs138672528 by1000genomes TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_144773.2 -1 reviewed p.V115M 1.000 201 0% 176 23.9% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_7tm_1,superfamily_SSF81321 ITSN1 6453 genome.wustl.edu 37 21 35144400 35144400 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_003024.2 +1 reviewed p.R360C 0.996 287 0.3% 250 18.4% 1 0% unknown(0) deleterious(0) - NULL DGCR8 54487 genome.wustl.edu 37 22 20079118 20079118 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_022720.5 +1 validated p.L489 1.000 174 0% 125 21.6% 7 28.5% - - - NULL SEZ6L 23544 genome.wustl.edu 37 22 26706651 26706651 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_021115.4 +1 validated p.S510 0.407 101 0% 91 19.8% 0 - - - - HMMSmart_SM00042,superfamily_Spermadhesin CUB domain ZC3H7B 23264 genome.wustl.edu 37 22 41752792 41752792 + Silent SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_017590.4 +1 reviewed p.G887 1.000 23 0% 29 20.7% 7 0% - - - HMMPfam_zf-CCCH,superfamily_SSF90229 SERHL2 253190 genome.wustl.edu 37 22 42950994 42950994 + Missense_Mutation SNP A A G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_014509.3 +1 provisional p.K25E 1.000 81 0% 108 13.9% 0 - probably_damaging(0.998) deleterious(0) deleterious(0.919) superfamily_alpha/beta-Hydrolases TRO 7216 genome.wustl.edu 37 X 54950037 54950037 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001039705.1 +1 reviewed p.P358S 0.001 79 0% 79 20.3% 3 0% benign(0.071) tolerated(0.42) neutral(0.019) NULL CYLC1 1538 genome.wustl.edu 37 X 83128725 83128725 + Missense_Mutation SNP T T A novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_021118.1 +1 provisional p.S337T 0.910 207 0% 132 19.7% 0 - unknown(0) tolerated(0.25) - NULL GPR112 139378 genome.wustl.edu 37 X 135430967 135430967 + Nonsense_Mutation SNP C C G novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_153834.3 +1 reviewed p.S1701* 0.020 250 0% 228 23.7% 0 - - - - NULL FGF13 2258 genome.wustl.edu 37 X 137715055 137715055 + Missense_Mutation SNP C C T novel TCGA-A5-A0GQ-01A-11D-A122-09 TCGA-A5-A0GQ-10A-01D-A122-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b47abded-6162-4d87-8219-f4401f158ed7 6271fc73-3441-4a4b-bedc-2142e613fa08 NM_001139500.1 -1 reviewed p.V242M 0.921 265 0% 309 19.4% 0 - benign(0) deleterious(0.04) neutral(0.349) NULL