Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain KAZ 23254 genome.wustl.edu 37 1 15430678 15430678 + Missense_Mutation SNP C C A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_201628.2 +1 validated p.P681T 1.000 10 0% 26 53.8% 0 - benign(0.328) deleterious(0.01) deleterious(0.509) superfamily_SAM/Pointed domain ARID1A 8289 genome.wustl.edu 37 1 27100207 27100207 + Nonsense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_006015.4 +1 reviewed p.R1335* 0.945 78 0% 121 55.4% 8 50% - - - NULL GBP1 2633 genome.wustl.edu 37 1 89521740 89521740 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_002053.2 -1 validated p.L443 0.033 199 0% 344 42.7% 2 0% - - - HMMPfam_GBP_C,superfamily_Interferon-induced guanylate-binding protein 1 (GBP1) C-terminal domain CCDC18 343099 genome.wustl.edu 37 1 93724433 93724433 + Silent SNP T T C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 ENST00000421014 +1 known p.I971T 0.998 90 0% 365 44.4% 11 63.6% - - - NULL FLG 2312 genome.wustl.edu 37 1 152280891 152280891 + Silent SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_002016.1 -1 reviewed p.S2157 0.000 185 0% 558 33% 0 - - - - NULL INSRR 3645 genome.wustl.edu 37 1 156814623 156814623 + Missense_Mutation SNP C C A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_014215.1 -1 validated p.G817V 0.996 17 0% 47 19.1% 0 - benign(0) deleterious(0.04) neutral(0.349) HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like APOBEC4 403314 genome.wustl.edu 37 1 183617486 183617486 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_203454.2 -1 reviewed p.T144M 0.000 125 0% 359 57.9% 0 - benign(0.028) tolerated(0.11) neutral(0.273) HMMPfam_APOBEC_N ADSS 159 genome.wustl.edu 37 1 244583581 244583581 + Frame_Shift_Del DEL A A - novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001126.2 -1 reviewed p.K228fs 0.999 - - - - - - - - - HMMPfam_Adenylsucc_synt,HMMSmart_SM00788,superfamily_P-loop containing nucleoside triphosphate hydrolases BIRC6 57448 genome.wustl.edu 37 2 32692987 32692987 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_016252.3 +1 reviewed p.R1863H 1.000 70 0% 105 49.5% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) NULL EML6 400954 genome.wustl.edu 37 2 55040504 55040504 + Silent SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001039753.2 +1 validated p.C111 1.000 142 0% 563 40% 0 - - - - HMMSmart_SM00320,superfamily_YVTN repeat-like/Quinoprotein amine dehydrogenase,HMMPfam_WD40 ZNF2 7549 genome.wustl.edu 37 2 95845938 95845938 + Silent SNP A A G novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 ENST00000453539 +1 known p.Q65 0.934 109 0% 390 47.4% 2 0% - - - HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352) SLC25A12 8604 genome.wustl.edu 37 2 172650225 172650225 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_003705.3 -1 reviewed p.R453H 1.000 85 1.2% 240 48.3% 8 50% probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_Mitoch_carrier,HMMPfam_Mito_carr CD28 940 genome.wustl.edu 37 2 204591400 204591400 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_006139.2 +1 validated p.D33N 0.000 49 0% 179 50.8% 0 - benign(0) tolerated(1) - superfamily_Immunoglobulin SPEG 10290 genome.wustl.edu 37 2 220353302 220353302 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_005876.4 +1 validated p.A2647 0.745 12 0% 12 41.7% 0 - - - - HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin SEC13 6396 genome.wustl.edu 37 3 10354272 10354272 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_183352.1 -1 reviewed p.D103N 1.000 50 0% 61 45.9% 88 44.3% benign(0.007) tolerated(0.12) neutral(0.261) HMMSmart_WD40,superfamily_WD40_like,HMMPfam_WD40 LOC100132526 100132526 genome.wustl.edu 37 3 13976616 13976616 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 XM_001721212.1 +1 model p.V23I 0.611 13 0.000 5 0.800 0 - - - - NULL EPM2AIP1 9852 genome.wustl.edu 37 3 37034364 37034364 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_014805.3 -1 reviewed p.V69M 0.583 8 0.000 17 0.588 2 0% probably_damaging(0.982) tolerated(0.14) deleterious(0.676) NULL CTNNB1 1499 genome.wustl.edu 37 3 41266113 41266113 + Missense_Mutation SNP C C G rs121913403 byCluster TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001098209.1 +1 reviewed p.S37C 1.000 47 0% 85 38.8% 39 17.9% probably_damaging(1) deleterious(0) deleterious(0.945) NULL CTNNB1 1499 genome.wustl.edu 37 3 41277973 41277973 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001098209.1 +1 reviewed p.S646F 0.999 299 0% 513 46% 88 46.5% probably_damaging(0.997) tolerated(0.08) deleterious(0.766) HMMPfam_Arm,HMMSmart_SM00185,superfamily_ARM repeat PROS1 5627 genome.wustl.edu 37 3 93615535 93615535 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_000313.3 -1 reviewed p.V284I 0.977 76 0% 106 37.7% 1 0% benign(0.001) tolerated(0.19) neutral(0.050) superfamily_ConA_like_lec_gl C3orf27 23434 genome.wustl.edu 37 3 128292319 128292320 + Frame_Shift_Del DEL TC TC - rs147519916 byCluster;by1000genomes TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 TC TC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_007354.1 -1 provisional p.D85fs 0.075:0.076 - - - - - - - - - NULL IGJ 3512 genome.wustl.edu 37 4 71527921 71527921 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_144646.3 -1 validated p.E26K 0.195 91 0% 144 47.2% 5 0% benign(0) tolerated(0.16) neutral(0.059) NULL RXFP1 59350 genome.wustl.edu 37 4 159568032 159568032 + Missense_Mutation SNP T T G novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_021634.2 +1 provisional p.W479G 1.000 136 0% 288 46.5% 4 75% possibly_damaging(0.728) deleterious(0.03) deleterious(0.629) HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like MARCH11 441061 genome.wustl.edu 37 5 16067889 16067889 + Missense_Mutation SNP A A C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001102562.1 -1 provisional p.H300Q 0.707 49 0% 254 30.3% 0 - probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL PIK3R1 5295 genome.wustl.edu 37 5 67591037 67591037 + Nonsense_Mutation SNP A A T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_181523.1 +1 reviewed p.R544* 0.377 169 0% 299 43.8% 22 40.9% - - - NULL PIK3R1 5295 genome.wustl.edu 37 5 67591115 67591116 + Frame_Shift_Ins INS - - T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_181523.1 +1 reviewed p.I571fs 1.000:1.000 - - - - - - - - - NULL VCAN 1462 genome.wustl.edu 37 5 82833400 82833401 + Frame_Shift_Ins INS - - A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_004385.4 +1 reviewed p.T1526fs 0.000:0.000 - - - - - - - - - NULL PCDHB6 56130 genome.wustl.edu 37 5 140532010 140532010 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_018939.2 +1 reviewed p.S724 0.000 32 0% 83 47% 2 50% - - - NULL SLIT3 6586 genome.wustl.edu 37 5 168137914 168137914 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_003062.2 -1 validated p.R902H 1.000 5 0.000 23 0.478 8 25% benign(0.036) tolerated(0.14) neutral(0.252) HMMPfam_LRRCT,HMMSmart_SM00082,superfamily_L domain-like TREM2 54209 genome.wustl.edu 37 6 41126749 41126749 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_018965.2 -1 reviewed p.A180T 1.000 55 0% 207 41.1% 18 0% possibly_damaging(0.842) deleterious(0.03) deleterious(0.686) NULL RSPH9 221421 genome.wustl.edu 37 6 43623347 43623347 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_152732.3 +1 provisional p.D148N 1.000 38 0% 138 44.9% 0 - probably_damaging(1) tolerated(0.13) deleterious(0.752) NULL CAPN11 11131 genome.wustl.edu 37 6 44140158 44140158 + Splice_Site SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_007058.3 +1 reviewed e5+1 1.000 51 0% 103 45.6% 0 - - - - - EIF2AK1 27102 genome.wustl.edu 37 7 6080612 6080612 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_014413.3 -1 reviewed p.P344S 0.001 120 0% 213 34.3% 39 28.2% benign(0) tolerated(0.87) neutral(0.001) HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase IKZF1 10320 genome.wustl.edu 37 7 50467971 50467971 + Missense_Mutation SNP C C A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 ENST00000331340 +1 known p.S402R 1.000 7 0.000 20 0.250 0 - probably_damaging(0.988) deleterious(0.04) deleterious(0.786) NULL RFC2 5982 genome.wustl.edu 37 7 73668699 73668699 + Silent SNP G G A rs150851734 by1000genomes TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_181471.1 -1 reviewed p.A5 0.000 8 0.000 8 0.500 8 75% - - - NULL ATP6V0A4 50617 genome.wustl.edu 37 7 138444495 138444495 + Splice_Site SNP A A G novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_020632.2 -1 reviewed e6+2 1.000 47 0% 217 25.8% 5 100% - - - - KIAA0146 23514 genome.wustl.edu 37 8 48612995 48612995 + Silent SNP C C G novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001080394.1 +1 predicted p.T572 0.543 114 0% 317 40.1% 11 36.3% - - - NULL CHD7 55636 genome.wustl.edu 37 8 61769105 61769105 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_017780.2 +1 reviewed p.E2422 1.000 74 0% 155 44.5% 4 50% - - - NULL PREX2 80243 genome.wustl.edu 37 8 69104650 69104650 + Silent SNP T T C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_024870.2 +1 validated p.C1498 1.000 52 1.9% 129 45% 10 80% - - - NULL ZFHX4 79776 genome.wustl.edu 37 8 77768193 77768193 + Silent SNP C C T rs139869161 by1000genomes TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_024721.4 +1 validated p.C2967 1.000 27 0% 92 35.9% 0 - - - - HMMSmart_SM00451,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355 ADCY8 114 genome.wustl.edu 37 8 132051645 132051645 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001115.2 -1 reviewed p.R312Q 0.983 12 0% 26 46.2% 0 - possibly_damaging(0.774) tolerated(0.38) neutral(0.306) NULL PHF20L1 51105 genome.wustl.edu 37 8 133844570 133844570 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_016018.4 +1 validated p.R612Q 1.000 163 0% 369 46.6% 5 40% probably_damaging(0.994) tolerated(0.09) deleterious(0.748) NULL ANKRD18B 441459 genome.wustl.edu 37 9 33524338 33524339 + Frame_Shift_Ins INS - - ATCGCGGGTTTGGGGGTGG novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 XM_001718334.2 +1 model p.V125fs 0.562:0.557 - - - - - - - - - superfamily_Ankyrin repeat ENHO 375704 genome.wustl.edu 37 9 34521654 34521654 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_198573.2 -1 validated p.V14I 0.991 27 0% 46 37% 0 - benign(0) - - NULL CACNA1B 774 genome.wustl.edu 37 9 140846827 140846827 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_000718.2 +1 validated p.S356 0.858 58 0% 169 42% 0 - - - - superfamily_Voltage-gated potassium channels NRG3 10718 genome.wustl.edu 37 10 84118578 84118578 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001010848.3 +1 reviewed p.E303K 1.000 40 0% 222 27% 0 - probably_damaging(0.995) tolerated(0.06) deleterious(0.780) HMMPfam_EGF,HMMSmart_EGF,superfamily_SSF57196 PTEN 5728 genome.wustl.edu 37 10 89653842 89653842 + Frame_Shift_Del DEL G G - novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 ENST00000371953 +1 known p.N48fs 1.000 - - - - - - - - - HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II PTEN 5728 genome.wustl.edu 37 10 89720801 89720802 + Frame_Shift_Ins INS - - T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 ENST00000371953 +1 known p.T319fs 1.000:1.000 - - - - - - - - - superfamily_C2 domain (Calcium/lipid-binding domain CaLB),HMMPfam_PTEN_C2 FAM160A2 84067 genome.wustl.edu 37 11 6243762 6243762 + Silent SNP G G C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_032127.3 -1 validated p.L367 0.998 66 0% 269 41.6% 11 45.4% - - - HMMPfam_RAI16-like AMPD3 272 genome.wustl.edu 37 11 10517281 10517282 + Splice_Site INS - - T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_000480.2 +1 reviewed e9+1 1.000:1.000 - - - - - - - - - - LOC100287736 100287736 genome.wustl.edu 37 11 63033555 63033555 + Silent SNP G G A rs188846497 by1000genomes TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 XM_002343091.1 -1 model p.T58 0.000 23 0% 30 60% 0 - - - - NULL LRTOMT 220074 genome.wustl.edu 37 11 71817087 71817087 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001145308.1 +1 validated p.T63 0.874 13 0% 23 34.8% 0 - unknown(0) - - NULL APLP2 334 genome.wustl.edu 37 11 130010309 130010309 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001642.2 +1 validated p.E630 0.990 124 0% 538 45.7% 138 44.9% - - - NULL KCNA6 3742 genome.wustl.edu 37 12 4920526 4920526 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_002235.3 +1 reviewed p.S440L 1.000 57 0% 114 46.5% 0 - possibly_damaging(0.948) deleterious(0) deleterious(0.836) HMMPfam_Ion_trans,superfamily_SSF81324 EPS8 2059 genome.wustl.edu 37 12 15777246 15777246 + Nonsense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_004447.5 -1 reviewed p.Q714* 1.000 76 0% 402 46.3% 15 26.6% - - - NULL KRT6B 3854 genome.wustl.edu 37 12 52841192 52841192 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_005555.3 -1 reviewed p.V493I 0.005 46 0% 208 51.4% 1 0% unknown(0) tolerated(0.5) - NULL KIAA1033 23325 genome.wustl.edu 37 12 105558066 105558066 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_015275.1 +1 validated p.R1112Q 1.000 90 0% 246 43.1% 6 66.6% probably_damaging(1) deleterious(0.02) deleterious(0.883) NULL CAB39L 81617 genome.wustl.edu 37 13 49925022 49925022 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001079670.1 -1 validated p.R141H 1.000 95 0% 168 44.6% 5 0% benign(0.001) tolerated(0.33) neutral(0.024) HMMPfam_Mo25,superfamily_ARM-type_fold MAP4K5 11183 genome.wustl.edu 37 14 50912825 50912825 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_006575.3 -1 reviewed p.R386H 0.930 148 0% 277 47.7% 6 0% possibly_damaging(0.771) tolerated(0.21) neutral(0.330) superfamily_Protein kinase-like (PK-like) SECISBP2L 9728 genome.wustl.edu 37 15 49284892 49284892 + Missense_Mutation SNP T T G novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_014701.2 -1 provisional p.E907A 1.000 67 0% 310 37.1% 5 40% probably_damaging(1) deleterious(0) deleterious(0.945) NULL LOC100289289 100289289 genome.wustl.edu 37 15 62554431 62554431 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 XM_002343368.1 -1 model p.V293M 1.000 15 0% 21 76.2% 0 - - - - NULL HCN4 10021 genome.wustl.edu 37 15 73614890 73614890 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_005477.2 -1 reviewed p.A1182T 1.000 6 0.000 19 0.474 0 - possibly_damaging(0.888) deleterious(0) deleterious(0.792) NULL ADAMTS17 170691 genome.wustl.edu 37 15 100692832 100692832 + Missense_Mutation SNP G G T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_139057.2 -1 reviewed p.F486L 1.000 22 0% 25 48% 0 - probably_damaging(0.996) tolerated(1) neutral(0.462) HMMSmart_SM00608 PIGQ 9091 genome.wustl.edu 37 16 628842 628842 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_148920.1 +1 reviewed p.S376L 1.000 39 0% 19 42.1% 40 50% possibly_damaging(0.772) tolerated(0.1) deleterious(0.573) HMMPfam_Gpi1 VWA3A 146177 genome.wustl.edu 37 16 22142569 22142569 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_173615.3 +1 validated p.V566M 0.074 63 0% 281 49.5% 2 50% benign(0.006) tolerated(0.1) neutral(0.286) superfamily_vWA-like CDR2 1039 genome.wustl.edu 37 16 22361121 22361121 + Missense_Mutation SNP G G C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001802.1 -1 validated p.A81G 1.000 173 0% 416 41.6% 7 71.4% probably_damaging(0.998) deleterious(0.02) deleterious(0.857) NULL LHX1 3975 genome.wustl.edu 37 17 35297654 35297654 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_005568.2 +1 reviewed p.R80W 1.000 14 0% 11 45.5% 1 100% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_LIM,HMMSmart_LIM,PatternScan_LIM_DOMAIN_1,superfamily_SSF57716 ENSG00000228782 0 genome.wustl.edu 37 17 45567595 45567596 + Splice_Site DEL TC TC - novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 TC TC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 ENST00000425159 -1 known e3+2 0.724 - - - - - - - - - - SPOP 8405 genome.wustl.edu 37 17 47699360 47699360 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001007226.1 -1 reviewed p.E50K 1.000 107 0% 255 40% 9 33.3% benign(0.22) deleterious(0.05) neutral(0.367) HMMPfam_MATH,HMMSmart_SM00061,superfamily_TRAF domain-like C17orf101 79701 genome.wustl.edu 37 17 80373281 80373281 + Missense_Mutation SNP C C A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_175902.4 -1 validated p.R99S 0.866 32 0% 18 38.9% 22 59% possibly_damaging(0.436) tolerated(0.07) neutral(0.461) NULL LRRC30 339291 genome.wustl.edu 37 18 7231260 7231260 + Missense_Mutation SNP T T C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001105581.1 +1 provisional p.S42P 0.140 22 0% 38 44.7% 0 - benign(0.147) deleterious(0.04) neutral(0.362) superfamily_SSF52058 SERPINB3 6317 genome.wustl.edu 37 18 61326648 61326648 + Silent SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_006919.2 -1 validated p.T112 0.000 235 0% 489 38.9% 0 - - - - HMMPfam_Serpin,HMMSmart_SM00093,superfamily_Serpins C18orf62 284274 genome.wustl.edu 37 18 73139426 73139426 + Silent SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001037331.2 -1 provisional p.F31 0.000 115 0% 380 43.9% 0 - - - - NULL GATAD2A 54815 genome.wustl.edu 37 19 19605151 19605151 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_017660.3 +1 provisional p.R195W 0.997 22 0% 29 51.7% 18 33.3% probably_damaging(1) deleterious(0.01) deleterious(0.905) NULL USF2 7392 genome.wustl.edu 37 19 35769888 35769888 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_003367.2 +1 reviewed p.R288W 1.000 15 0% 18 44.4% 189 44.9% probably_damaging(0.999) deleterious(0.03) deleterious(0.855) HMMPfam_HLH,HMMSmart_SM00353,superfamily_HLH helix-loop-helix DNA-binding domain KRTAP19-2 337969 genome.wustl.edu 37 21 31859640 31859640 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_181608.1 -1 provisional p.G10S 0.000 48 0% 171 52% 0 - unknown(0) - - NULL RBBP7 5931 genome.wustl.edu 37 X 16875775 16875775 + Missense_Mutation SNP T T C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_002893.3 -1 reviewed p.Y180C 1.000 159 0% 378 42.3% 228 99.5% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40 MAP3K15 389840 genome.wustl.edu 37 X 19428044 19428044 + Missense_Mutation SNP T T C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001001671.3 -1 validated p.K25E 1.000 406 0% 383 40.5% 0 - probably_damaging(0.974) deleterious(0) deleterious(0.861) NULL FAM48B2 170067 genome.wustl.edu 37 X 24329039 24329039 + Silent SNP T T C novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001136233.1 -1 provisional p.Q798 0.000 49 0% 115 44.3% 0 - - - - NULL SH3BGRL 6451 genome.wustl.edu 37 X 80533839 80533839 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_003022.2 +1 validated p.A81T 1.000 120 0% 382 43.2% 46 86.9% probably_damaging(0.982) tolerated(0.24) neutral(0.464) HMMPfam_SH3BGR,superfamily_Thioredoxin-like DACH2 117154 genome.wustl.edu 37 X 85769338 85769338 + Missense_Mutation SNP G G A novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_053281.3 +1 reviewed p.R195H 1.000 50 0% 212 45.8% 0 - benign(0.361) tolerated(0.49) neutral(0.125) NULL GPRASP1 9737 genome.wustl.edu 37 X 101910400 101910400 + Missense_Mutation SNP C C T novel TCGA-BG-A0M3-01A-11W-A10C-09 TCGA-BG-A0M3-10A-01D-A127-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 6915ff9b-f798-4960-bef8-716d0d93c31a 016d88a4-1bc5-4103-92a7-9a83231b9375 NM_001099410.1 +1 reviewed p.S520L 0.929 59 0% 185 53% 2 50% possibly_damaging(0.839) deleterious(0.03) deleterious(0.685) NULL