Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain USP48 84196 genome.wustl.edu 37 1 22078013 22078013 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_032236.5 -1 reviewed p.S254L 1.000 175 0% 311 38.3% 21 33.3% benign(0.001) tolerated(0.2) neutral(0.049) HMMPfam_UCH,superfamily_Cysteine proteinases ARID1A 8289 genome.wustl.edu 37 1 27106799 27106799 + Frame_Shift_Del DEL C C - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_006015.4 +1 reviewed p.T2138fs 1.000 - - - - - - - - - NULL ZMYM6 9204 genome.wustl.edu 37 1 35476529 35476529 + Missense_Mutation SNP C C G novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_007167.3 -1 validated p.G391R 0.002 74 0% 112 38.4% 3 0% probably_damaging(0.986) tolerated(0.37) neutral(0.454) NULL AGL 178 genome.wustl.edu 37 1 100356892 100356892 + Nonsense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_000028.2 +1 reviewed p.R977* 0.998 193 0% 327 36.1% 3 0% - - - NULL ZBTB7B 51043 genome.wustl.edu 37 1 154988209 154988235 + In_Frame_Del DEL CAGGCAAACTGCCTCGCCACATGAGGA CAGGCAAACTGCCTCGCCACATGAGGA - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 CAGGCAAACTGCCTCGCCACATGAGGA CAGGCAAACTGCCTCGCCACATGAGGA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_015872.2 +1 validated p.GKLPRHMRT359in_frame_del 0.992:0.006:0.981:1.000:1.000:1.000:1.000:0.991:1.000:1.000:1.000:1.000:1.000:0.902:1.000:1.000:0.979:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000 - - - - - - - - - PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 ZBTB7B 51043 genome.wustl.edu 37 1 154988235 154988235 + Missense_Mutation SNP A A G novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_015872.2 +1 validated p.T367A 1.000 25 0% 22 31.8% 20 10% possibly_damaging(0.862) deleterious(0.02) deleterious(0.716) PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 ADAM15 8751 genome.wustl.edu 37 1 155032820 155032820 + Splice_Site SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_207197.1 +1 reviewed e18+1 0.999 56 0% 136 60.3% 5 100% - - - - SCAMP3 10067 genome.wustl.edu 37 1 155226122 155226122 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_005698.2 -1 reviewed p.R329Q 1.000 19 0% 47 21.3% 172 30.2% unknown(0) tolerated(0.92) - NULL CLK2 1196 genome.wustl.edu 37 1 155234212 155234212 + Nonsense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000424156 -1 known p.W170* 0.000 104 0% 268 22.8% 3 66.6% - - - HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like) RGS16 6004 genome.wustl.edu 37 1 182571199 182571199 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_002928.3 -1 reviewed p.A97T 1.000 88 0% 220 17.7% 62 27.4% probably_damaging(1) deleterious(0.03) deleterious(0.865) HMMPfam_RGS,HMMSmart_SM00315,superfamily_Regulator of G-protein signaling RGS C4BPA 722 genome.wustl.edu 37 1 207317180 207317180 + Missense_Mutation SNP G G C novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_000715.3 +1 reviewed p.E488Q 0.017 437 0% 522 20.1% 16 31.2% benign(0.364) tolerated(0.31) neutral(0.143) HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain HHIPL2 79802 genome.wustl.edu 37 1 222696035 222696035 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_024746.3 -1 validated p.R695C 0.090 172 0% 411 64.2% 0 - benign(0.025) deleterious(0.01) neutral(0.407) NULL OR2W5 441932 genome.wustl.edu 37 1 247654943 247654943 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001004698.2 +1 validated p.R172C 0.000 56 0% 159 25.2% 0 - - - - HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like OR14K1 343170 genome.wustl.edu 37 1 247902807 247902807 + Silent SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000283225 +1 known p.S297 0.000 151 0% 304 21.1% 1 0% - - - superfamily_SSF81321 PUM2 23369 genome.wustl.edu 37 2 20508090 20508090 + Silent SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_015317.1 -1 provisional p.Y258 1.000 37 0% 54 37% 5 100% - - - NULL MOB1A 55233 genome.wustl.edu 37 2 74392328 74392328 + Silent SNP C C A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000409969 -1 known p.S142 0.003 122 0% 144 39.6% 0 - - - - HMMPfam_Mob1_phocein CDK15 65061 genome.wustl.edu 37 2 202698630 202698630 + Silent SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_139158.1 +1 provisional p.H171 1.000 594 0% 332 35.2% 0 - - - - HMMSmart_SM00219,HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase ABCA12 26154 genome.wustl.edu 37 2 215823162 215823162 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_173076.2 -1 reviewed p.D1986N 0.997 163 0% 187 41.7% 0 - benign(0.188) deleterious(0.01) neutral(0.423) NULL VHL 7428 genome.wustl.edu 37 3 10188287 10188287 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_000551.2 +1 reviewed p.G144R 1.000 226 0% 315 38.1% 20 25% probably_damaging(0.987) deleterious(0.01) deleterious(0.842) HMMPfam_VHL,superfamily_VHL SEMA3F 6405 genome.wustl.edu 37 3 50211311 50211316 + In_Frame_Del DEL CGACCG CGACCG - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 CGACCG CGACCG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_004186.3 +1 validated p.DR67in_frame_del 0.885:1.000:1.000:1.000:1.000:1.000 - - - - - - - - - HMMPfam_Sema,HMMSmart_Sema,superfamily_Sema CPOX 1371 genome.wustl.edu 37 3 98304389 98304389 + Missense_Mutation SNP G G C novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_000097.5 -1 reviewed p.S356R 1.000 54 0% 84 50% 13 30.7% possibly_damaging(0.52) deleterious(0.02) deleterious(0.558) HMMPfam_Coprogen_oxidas,superfamily_Coprogen_oxidas PIK3CA 5290 genome.wustl.edu 37 3 178928110 178928115 + In_Frame_Del DEL GATCAA GATCAA - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 GATCAA GATCAA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_006218.2 +1 reviewed p.GSN463in_frame_delD 1.000:0.997:1.000:1.000:1.000:1.000 - - - - - - - - - HMMPfam_PI3K_C2,superfamily_C2_CaLB METAP1 23173 genome.wustl.edu 37 4 99978957 99978957 + Missense_Mutation SNP A A G novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_015143.2 +1 validated p.M329V 1.000 812 0% 560 39.1% 54 53.7% benign(0.356) deleterious(0) deleterious(0.557) HMMPfam_Peptidase_M24,superfamily_Creatinase/aminopeptidase KIF2A 3796 genome.wustl.edu 37 5 61654113 61654113 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001098511.1 +1 validated p.E287K 1.000 142 0% 263 38% 6 33.3% probably_damaging(1) deleterious(0.04) deleterious(0.849) HMMPfam_Kinesin,HMMSmart_KISc,superfamily_SSF52540 PCDHA10 56139 genome.wustl.edu 37 5 140237073 140237073 + Silent SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_018901.2 +1 reviewed p.D480 1.000 11 0% 43 74.4% 0 - - - - HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like ZFAND3 60685 genome.wustl.edu 37 6 38120118 38120118 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_021943.2 +1 validated p.R213W 1.000 40 0% 93 47.3% 81 60.4% probably_damaging(1) deleterious(0) deleterious(0.945) NULL MANEA 79694 genome.wustl.edu 37 6 96034881 96034882 + Frame_Shift_Ins INS - - TATG rs78175628 TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000369293 +1 known p.V190fs 0.000:0.000 - - - - - - - - - NULL PARK2 5071 genome.wustl.edu 37 6 161990445 161990445 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_004562.2 -1 reviewed p.G292D 1.000 151 0% 262 46.2% 0 - benign(0.054) deleterious(0.01) neutral(0.409) NULL SPDYE5 442590 genome.wustl.edu 37 7 75126032 75126032 + Missense_Mutation SNP T T C novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001099435.2 +1 validated p.F99L 0.002 380 0% 331 16.3% 2 0% - - - NULL TECPR1 25851 genome.wustl.edu 37 7 97863162 97863162 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_015395.1 -1 provisional p.D415N 0.976 5 0.000 38 0.395 7 28.5% possibly_damaging(0.951) tolerated(0.42) neutral(0.408) NULL OR6B1 135946 genome.wustl.edu 37 7 143701315 143701315 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001005281.1 +1 provisional p.V76M 0.022 164 0% 215 36.7% 0 - probably_damaging(0.999) deleterious(0.01) deleterious(0.896) HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like KIF5B 3799 genome.wustl.edu 37 10 32306235 32306235 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_004521.2 -1 validated p.R866Q 1.000 273 0% 370 41.9% 41 53.6% probably_damaging(1) deleterious(0.01) deleterious(0.905) NULL PTEN 5728 genome.wustl.edu 37 10 89624254 89624256 + In_Frame_Del DEL AGC AGC - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 AGC AGC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000371953 +1 known p.S10in_frame_del 1.000:1.000:1.000 - - - - - - - - - NULL PTEN 5728 genome.wustl.edu 37 10 89717609 89717609 + Splice_Site SNP G G C novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000371953 +1 known e7-1 1.000 204 0.5% 136 44.1% 1 100% - - - - PSD 5662 genome.wustl.edu 37 10 104176485 104176485 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_002779.3 -1 provisional p.R104H 1.000 6 0.000 23 0.217 0 - probably_damaging(0.969) deleterious(0) deleterious(0.856) NULL SYT8 90019 genome.wustl.edu 37 11 1858596 1858596 + Nonsense_Mutation SNP G G T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_138567.3 +1 validated p.E381* 0.857 3 0.000 25 0.520 0 - - - - NULL VWCE 220001 genome.wustl.edu 37 11 61026327 61026327 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000301770 -1 known p.G610R 0.000 22 0% 75 50.7% 5 20% - - - NULL PC 5091 genome.wustl.edu 37 11 66631260 66631260 + Silent SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_000920.3 -1 reviewed p.R451 0.004 14 0% 97 48.5% 7 57.1% - - - HMMPfam_Biotin_carb_C,superfamily_Rudmnt_hyb_motif ATM 472 genome.wustl.edu 37 11 108180958 108180959 + Frame_Shift_Del DEL CT CT - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 CT CT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_000051.3 +1 reviewed p.Q1946fs 1.000:0.999 - - - - - - - - - superfamily_ARM repeat NUAK1 9891 genome.wustl.edu 37 12 106480618 106480618 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_014840.2 -1 validated p.S136N 1.000 160 0% 108 46.3% 0 - possibly_damaging(0.801) deleterious(0.04) deleterious(0.650) HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase DHRS4L2 317749 genome.wustl.edu 37 14 24470115 24470115 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_198083.2 +1 validated p.A151V 0.815 488 0% 486 33.3% 25 0% benign(0.008) tolerated(0.24) neutral(0.037) HMMPfam_adh_short,superfamily_NAD(P)-binding Rossmann-fold domains HECTD1 25831 genome.wustl.edu 37 14 31590627 31590627 + Missense_Mutation SNP C C G novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_015382.2 -1 validated p.V1734L 0.999 20 0% 73 43.8% 35 57.1% benign(0) tolerated(0.55) neutral(0.007) NULL KIF7 374654 genome.wustl.edu 37 15 90174806 90174806 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_198525.2 -1 validated p.R1011C 1.000 16 0% 25 40% 7 42.8% probably_damaging(1) tolerated(0.12) deleterious(0.760) NULL USP7 7874 genome.wustl.edu 37 16 8999107 8999107 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_003470.2 -1 validated p.D504N 1.000 218 0.5% 194 36.1% 44 43.1% benign(0.002) tolerated(0.58) neutral(0.005) HMMPfam_UCH,superfamily_SSF54001 SLC9A5 6553 genome.wustl.edu 37 16 67293485 67293485 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_004594.2 +1 validated p.V546I 0.999 70 0% 212 34% 0 - benign(0.016) tolerated(0.55) neutral(0.007) NULL SGSM2 9905 genome.wustl.edu 37 17 2274578 2274578 + Missense_Mutation SNP G G T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_014853.2 +1 validated p.M482I 1.000 5 0.000 30 0.433 15 40% benign(0.205) tolerated(0.49) neutral(0.030) NULL RASD1 51655 genome.wustl.edu 37 17 17399468 17399470 + In_Frame_Del DEL TCT TCT - novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 TCT TCT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_016084.3 -1 reviewed p.K9in_frame_del 1.000:1.000:1.000 - - - - - - - - - NULL ZFP161 7541 genome.wustl.edu 37 18 5290626 5290626 + RNA DEL G G - rs147986085 byCluster;by1000genomes TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NR_026569.1 -1 validated NULL 0.990 - - - - - - - - - - ENSG00000231452 0 genome.wustl.edu 37 18 12068091 12068091 + Missense_Mutation SNP C C T rs145442565 by1000genomes TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 ENST00000455542 -1 known p.R57Q 1.000 11 0% 31 45.2% 1 0% - - - NULL KCNG2 26251 genome.wustl.edu 37 18 77659559 77659559 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_012283.1 +1 reviewed p.G382R 1.000 18 0% 38 31.6% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Ion_trans,superfamily_SSF81324 ZNF536 9745 genome.wustl.edu 37 19 31040282 31040282 + Silent SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_014717.1 +1 provisional p.E1252 1.000 6 0.000 19 0.474 0 - - - - NULL LENG9 94059 genome.wustl.edu 37 19 54973989 54973991 + In_Frame_Del DEL CCT CCT - rs140013148 byCluster;by1000genomes TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 CCT CCT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_198988.1 -1 validated p.E262in_frame_del 0.000:0.000:0.000 - - - - - - - - - NULL TTLL9 164395 genome.wustl.edu 37 20 30522508 30522508 + Missense_Mutation SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001008409.2 +1 provisional p.T274M 0.999 15 0% 39 28.2% 0 - benign(0.001) tolerated(0.17) neutral(0.059) HMMPfam_TTL,superfamily_Glutathione synthetase ATP-binding domain-like EIF2S3 1968 genome.wustl.edu 37 X 24091292 24091292 + Missense_Mutation SNP G G T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001415.3 +1 reviewed p.D423Y 1.000 450 0% 402 39.8% 387 45.4% possibly_damaging(0.949) deleterious(0) deleterious(0.838) superfamily_EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain,HMMPfam_eIF2_C FOXO4 4303 genome.wustl.edu 37 X 70316510 70316510 + Silent SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_005938.3 +1 reviewed p.P44 0.000 57 0% 64 40.6% 4 0% - - - NULL RGAG4 340526 genome.wustl.edu 37 X 71350299 71350299 + Silent SNP C C T novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_001024455.3 -1 validated p.K364 0.000 325 0% 384 38.5% 0 - - - - NULL GLUD2 2747 genome.wustl.edu 37 X 120181719 120181719 + Missense_Mutation SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_012084.3 +1 reviewed p.E61K 0.133 6 0.000 27 0.519 1 0% benign(0.001) tolerated(0.3) neutral(0.029) superfamily_SSF53223 HCFC1 3054 genome.wustl.edu 37 X 153220133 153220133 + Silent SNP G G A novel TCGA-BG-A0MT-01A-11D-A10B-09 TCGA-BG-A0MT-10A-01W-A10C-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 5b1aa196-8837-4be0-8401-0cd7a396bedf 3a3ded86-403d-4780-b7d6-a947fcee5d40 NM_005334.2 -1 reviewed p.T1239 0.326 9 0.000 54 0.259 19 0% - - - NULL