Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	transcript_name	strand	transcript_status	amino_acid_change	ucsc_cons	normal_depth	normal_vaf	tumor_depth	tumor_vaf	rna_depth	rna_vaf	polyphen	sift	condel	domain
UROD	7389	genome.wustl.edu	37	1	45479419	45479419	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_000374.3	+1	reviewed	p.R144*	0.997	105	0%	150	46%	28	3.5%	-	-	-	HMMPfam_URO-D,superfamily_UROD/MetE-like
ACOT11	26027	genome.wustl.edu	37	1	55059614	55059614	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_015547.2	+1	reviewed	p.V125L	1.000	102	0%	153	42.5%	3	33.3%	probably_damaging(0.995)	deleterious(0.01)	deleterious(0.863)	HMMPfam_4HBT,superfamily_Thioesterase/thiol ester dehydrase-isomerase
SLC44A3	126969	genome.wustl.edu	37	1	95330435	95330435	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_001114106.1	+1	validated	p.Q459*	0.003	265	0%	80	35%	35	5.7%	-	-	-	HMMPfam_DUF580
KCNA10	3744	genome.wustl.edu	37	1	111060345	111060345	+	Silent	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_005549.2	-1	reviewed	p.S355	1.000	90	0%	80	48.7%	0	-	-	-	-	HMMPfam_Ion_trans,superfamily_SSF81324
LAMC2	3918	genome.wustl.edu	37	1	183197592	183197592	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_005562.2	+1	reviewed	p.Q518*	1.000	131	0%	95	49.5%	16	18.7%	-	-	-	HMMPfam_Laminin_EGF,HMMSmart_SM00180,superfamily_EGF/Laminin
AGT	183	genome.wustl.edu	37	1	230846279	230846279	+	Silent	SNP	G	G	A	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_000029.3	-1	reviewed	p.V106	0.058	143	0%	336	39%	3	0%	-	-	-	HMMPfam_Serpin,superfamily_Serpins
LOC100288163	100288163	genome.wustl.edu	37	2	101890949	101890949	+	Frame_Shift_Del	DEL	A	A	-	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	XM_002342243.1	-1	model	p.F36fs	1.000	-	-	-	-	-	-	-	-	-	HMMPfam_Pro_isomerase,superfamily_Cyclophilin-like
CAMKV	79012	genome.wustl.edu	37	3	49898436	49898436	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_024046.3	-1	validated	p.G193D	0.998	61	0%	98	42.9%	0	-	possibly_damaging(0.895)	deleterious(0.04)	deleterious(0.702)	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase
HCLS1	3059	genome.wustl.edu	37	3	121350798	121350798	+	Silent	SNP	G	G	A	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_005335.4	-1	validated	p.D452	0.996	167	0%	99	34.3%	10	0%	-	-	-	HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain
GRIA1	2890	genome.wustl.edu	37	5	153026596	153026596	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_000827.3	+1	reviewed	p.T110M	1.000	208	0%	83	43.4%	0	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_ANF_receptor,superfamily_Periplasmic binding protein-like I
C6orf132	647024	genome.wustl.edu	37	6	42075105	42075131	+	In_Frame_Del	DEL	GGTGGGGGTTCCAGCAGCAGGGGAGGT	GGTGGGGGTTCCAGCAGCAGGGGAGGT	-	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	GGTGGGGGTTCCAGCAGCAGGGGAGGT	GGTGGGGGTTCCAGCAGCAGGGGAGGT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	ENST00000341865	-1	known	p.LLLEPPPPP176in_frame_del	0.977:0.955:0.954:0.987:0.998:0.966:1.000:1.000:1.000:0.998:0.999:0.999:1.000:0.999:1.000:1.000:0.996:0.996:0.994:0.988:0.979:0.999:1.000:0.997:0.996:0.963:0.342	-	-	-	-	-	-	-	-	-	NULL
FIGNL1	63979	genome.wustl.edu	37	7	50514264	50514265	+	Frame_Shift_Ins	INS	-	-	AC	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_001042762.1	-1	validated	p.F241fs	0.800:0.869	-	-	-	-	-	-	-	-	-	NULL
UNC5D	137970	genome.wustl.edu	37	8	35608225	35608225	+	Silent	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_080872.2	+1	validated	p.A687	0.337	248	0%	108	12%	0	-	-	-	-	NULL
TMEM67	91147	genome.wustl.edu	37	8	94767235	94767235	+	Silent	SNP	T	T	G	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_153704.5	+1	reviewed	p.P31	0.000	88	0%	195	33.3%	17	47%	-	-	-	NULL
C9orf86	55684	genome.wustl.edu	37	9	139735053	139735053	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	ENST00000371673	+1	known	p.R400H	0.000	4	0.000	13	0.615	79	51.8%	unknown(0)	-	-	NULL
CHRNA10	57053	genome.wustl.edu	37	11	3688617	3688617	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_020402.2	-1	provisional	p.C247Y	1.000	4	0.000	14	0.500	0	-	unknown(0)	-	-	HMMPfam_Neur_chan_memb,superfamily_Neu_channel_TM
RRAS2	22800	genome.wustl.edu	37	11	14316389	14316389	+	Missense_Mutation	SNP	T	T	G	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_012250.5	-1	reviewed	p.Q72H	1.000	146	0%	44	52.3%	20	50%	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases
PTPRO	5800	genome.wustl.edu	37	12	15636976	15636976	+	Silent	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_030667.1	+1	reviewed	p.D48	0.963	167	0%	44	43.2%	0	-	-	-	-	superfamily_Fibronectin type III
ERBB3	2065	genome.wustl.edu	37	12	56481806	56481806	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_001982.2	+1	reviewed	p.A245V	1.000	172	0%	204	41.2%	6	66.6%	possibly_damaging(0.73)	tolerated(0.06)	deleterious(0.589)	HMMPfam_Furin-like,HMMSmart_SM00261,superfamily_Growth factor receptor domain
DIO3	1735	genome.wustl.edu	37	14	102027971	102027971	+	Silent	SNP	C	C	A	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_001362.3	+1	reviewed	p.L20	1.000	29	0%	50	38%	3	0%	-	-	-	HMMPfam_T4_deiodinase
AKT1	207	genome.wustl.edu	37	14	105243045	105243045	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_001014431.1	-1	reviewed	p.W80R	1.000	44	0%	73	39.7%	78	38.4%	possibly_damaging(0.952)	deleterious(0.01)	deleterious(0.801)	HMMPfam_PH,HMMSmart_SM00233,superfamily_PH domain-like
LRRC37A3	374819	genome.wustl.edu	37	17	62855667	62855667	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_199340.2	-1	provisional	p.E1533K	0.102	120	0%	74	35.1%	5	40%	benign(0.224)	deleterious(0.02)	neutral(0.405)	NULL
NLRP8	126205	genome.wustl.edu	37	19	56459555	56459555	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_176811.2	+1	provisional	p.R96H	0.000	185	0%	180	37.2%	0	-	probably_damaging(0.972)	tolerated(0.1)	deleterious(0.700)	HMMPfam_PAAD_DAPIN,superfamily_DEATH domain
SLC12A5	57468	genome.wustl.edu	37	20	44674992	44674992	+	Nonsense_Mutation	SNP	C	C	A	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_001134771.1	+1	reviewed	p.C591*	1.000	180	0%	200	45%	0	-	-	-	-	HMMPfam_AA_permease
MAGEA11	4110	genome.wustl.edu	37	X	148797815	148797815	+	Silent	SNP	T	T	C	novel		TCGA-BG-A0YU-01A-21D-A10M-09	TCGA-BG-A0YU-10A-01D-A10M-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	06d51140-9d6f-40be-a1b1-adbca81b936b	132a2cdd-e2df-4a42-b379-e92ce6e1c13d	NM_005366.4	+1	reviewed	p.H223	0.000	151	0%	168	36.3%	0	-	-	-	-	NULL