Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain ARID1A 8289 genome.wustl.edu 37 1 27100943 27100943 + Nonsense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_006015.4 +1 reviewed p.Q1409* 1.000 40 0% 39 33.3% - - - - - NULL INADL 10207 genome.wustl.edu 37 1 62253616 62253616 + Missense_Mutation SNP C C G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_176877.2 +1 reviewed p.P347R 0.992 74 0% 49 55.1% - - probably_damaging(1) tolerated(0.15) deleterious(0.741) superfamily_PDZ domain-like KCND3 3752 genome.wustl.edu 37 1 112524649 112524649 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_004980.3 -1 reviewed p.V234I 1.000 19 0% 36 16.7% - - probably_damaging(1) deleterious(0.03) deleterious(0.865) HMMPfam_Ion_trans,superfamily_Voltage-gated potassium channels NTRK1 4914 genome.wustl.edu 37 1 156843599 156843599 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_002529.3 +1 reviewed p.R342Q 0.019 63 0% 73 24.7% - - benign(0.421) tolerated(0.31) neutral(0.164) superfamily_Immunoglobulin ZBTB37 84614 genome.wustl.edu 37 1 173839915 173839915 + Missense_Mutation SNP C C G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001122770.1 +1 provisional p.I184M 0.934 88 0% 84 44% - - possibly_damaging(0.631) deleterious(0.02) deleterious(0.604) NULL NUCKS1 64710 genome.wustl.edu 37 1 205698749 205698749 + Missense_Mutation SNP T T G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_022731.3 -1 validated p.R6S 1.000 96 0% 93 43% - - unknown(0) deleterious(0) - NULL CR1 1378 genome.wustl.edu 37 1 207796353 207796353 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000651.4 +1 reviewed p.T2431M 0.000 434 0% 293 20.1% - - benign(0.001) tolerated(0.19) neutral(0.050) NULL VASH2 79805 genome.wustl.edu 37 1 213139111 213139111 + Missense_Mutation SNP C C A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001136474.1 +1 validated p.P73Q 1.000 151 0% 218 42.2% - - probably_damaging(1) deleterious(0) deleterious(0.945) NULL MARK1 4139 genome.wustl.edu 37 1 220808767 220808767 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_018650.3 +1 validated p.R391Q 1.000 179 0% 134 47.8% - - probably_damaging(0.96) tolerated(0.21) neutral(0.447) NULL OBSCN 84033 genome.wustl.edu 37 1 228467065 228467065 + Missense_Mutation SNP G G T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001098623.1 +1 reviewed p.R2439L 0.034 39 0% 35 42.9% - - benign(0.016) - - superfamily_Immunoglobulin OTOF 9381 genome.wustl.edu 37 2 26700144 26700144 + Nonsense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_194248.2 -1 reviewed p.Q807* 0.998 31 0% 44 29.5% - - - - - NULL MAP2 4133 genome.wustl.edu 37 2 210560807 210560807 + Missense_Mutation SNP G G T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_002374.3 +1 reviewed p.G1305W 0.825 102 0% 67 59.7% - - probably_damaging(0.993) deleterious(0) deleterious(0.895) HMMPfam_MAP2_projctn ZNF142 7701 genome.wustl.edu 37 2 219503327 219503327 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001105537.1 -1 validated p.R1600H 0.998 93 0% 104 48.1% - - probably_damaging(0.985) tolerated(0.15) deleterious(0.673) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers ANO7 50636 genome.wustl.edu 37 2 242148821 242148821 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001001891.3 +1 validated p.C454Y 1.000 24 0% 46 43.5% - - possibly_damaging(0.894) deleterious(0) deleterious(0.796) NULL GRM7 2917 genome.wustl.edu 37 3 6903318 6903318 + Silent SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_181874.2 +1 reviewed p.A81 0.999 25 0% 15 53.3% - - - - - HMMPfam_ANF_receptor,superfamily_SSF53822 ITIH1 3697 genome.wustl.edu 37 3 52818359 52818359 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_002215.2 +1 reviewed p.R425W 0.528 90 0% 108 35.2% - - probably_damaging(0.981) deleterious(0.02) deleterious(0.808) HMMPfam_VWA,HMMSmart_SM00327,superfamily_vWA-like ATR 545 genome.wustl.edu 37 3 142278180 142278180 + Missense_Mutation SNP T T C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001184.3 -1 reviewed p.S549G 0.436 163 0% 245 25.7% - - possibly_damaging(0.797) tolerated(0.12) deleterious(0.560) superfamily_ARM repeat MYNN 55892 genome.wustl.edu 37 3 169496818 169496818 + Missense_Mutation SNP T T C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_018657.3 +1 provisional p.S177P 0.672 96 0% 117 35% - - benign(0) tolerated(0.18) neutral(0.056) NULL FGFR3 2261 genome.wustl.edu 37 4 1808929 1808929 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000481110 +1 known p.R765C 0.085 31 0% 15 60% - - unknown(0) - - HMMSmart_SM00220 SH3TC1 54436 genome.wustl.edu 37 4 8230303 8230304 + In_Frame_Ins INS - - GGCCCAGCAGGGCAG novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_018986.3 +1 validated p.965in_frame_insGRAQQ 0.000:0.000 - - - - - - - - - superfamily_TPR-like PROM1 8842 genome.wustl.edu 37 4 15995679 15995679 + Silent SNP A A G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_006017.2 -1 reviewed p.N566 0.395 304 0% 216 54.6% - - - - - HMMPfam_Prominin PTTG2 10744 genome.wustl.edu 37 4 37962600 37962600 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_006607.2 +1 validated p.S182F 0.005 290 0% 197 34.5% - - benign(0.347) deleterious(0) deleterious(0.554) HMMPfam_Securin KIT 3815 genome.wustl.edu 37 4 55561763 55561763 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000222.2 +1 reviewed p.G51 0.016 198 0% 129 33.3% - - - - - superfamily_SSF48726 EPHA5 2044 genome.wustl.edu 37 4 66467434 66467434 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_004439.5 -1 reviewed p.E279K 1.000 114 0% 53 64.2% - - possibly_damaging(0.928) deleterious(0) deleterious(0.820) PatternScan_RECEPTOR_TYR_KIN_V_2 CXCL5 6374 genome.wustl.edu 37 4 74864043 74864043 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_002994.3 -1 reviewed p.A41V 0.000 91 0% 87 21.8% - - benign(0.235) deleterious(0.03) neutral(0.388) HMMPfam_IL8,superfamily_Interleukin 8-like chemokines PTPN13 5783 genome.wustl.edu 37 4 87679463 87679463 + Missense_Mutation SNP A A G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_080685.2 +1 reviewed p.T1092A 1.000 155 0% 53 28.3% - - benign(0.407) deleterious(0.02) deleterious(0.514) superfamily_PDZ ANKRD50 57182 genome.wustl.edu 37 4 125593026 125593026 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_020337.2 -1 validated p.A469V 0.999 99 0% 28 67.9% - - benign(0) tolerated(0.11) neutral(0.272) NULL FAT4 79633 genome.wustl.edu 37 4 126411905 126411905 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_024582.4 +1 validated p.R4643H 1.000 151 0.7% 113 32.7% - - probably_damaging(1) deleterious(0) deleterious(0.945) NULL PRDM9 56979 genome.wustl.edu 37 5 23526586 23526586 + Silent SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_020227.2 +1 provisional p.L463 0.000 150 0% 110 29.1% - - - - - NULL PDZD2 23037 genome.wustl.edu 37 5 32090567 32090567 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_178140.2 +1 reviewed p.R2338Q 1.000 39 0% 64 70.3% - - probably_damaging(1) deleterious(0) deleterious(0.945) NULL DHX29 54505 genome.wustl.edu 37 5 54565263 54565263 + Missense_Mutation SNP A A T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_019030.2 -1 validated p.I1091K 1.000 150 0% 65 30.8% - - probably_damaging(0.997) deleterious(0) deleterious(0.911) HMMPfam_HA2,superfamily_SSF52540 PCDHA2 56146 genome.wustl.edu 37 5 140175680 140175680 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_018905.2 +1 reviewed p.R377 0.052 70 0% 73 27.4% - - - - - HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like PCDHB14 56122 genome.wustl.edu 37 5 140604151 140604151 + Missense_Mutation SNP G G T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_018934.2 +1 reviewed p.E358D 1.000 96 0% 130 30% - - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Cadherin,superfamily_Cadherin RNF145 153830 genome.wustl.edu 37 5 158634775 158634775 + Missense_Mutation SNP T T A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_144726.1 -1 provisional p.L11F 0.800 316 0% 305 29.2% - - benign(0) - - NULL RNF145 153830 genome.wustl.edu 37 5 158634776 158634776 + Nonsense_Mutation SNP A A C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_144726.1 -1 provisional p.L11* 0.802 319 0% 305 29.2% - - - - - NULL GABRA6 2559 genome.wustl.edu 37 5 161116772 161116772 + Missense_Mutation SNP T T G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000811.2 +1 reviewed p.I220M 0.797 115 0% 55 34.5% - - possibly_damaging(0.818) deleterious(0.01) deleterious(0.715) HMMPfam_Neur_chan_LBD,superfamily_Nicotinic receptor ligand binding domain-like POU3F2 5454 genome.wustl.edu 37 6 99283169 99283170 + Frame_Shift_Ins INS - - C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_005604.2 +1 validated p.Q140fs 1.000:1.000 - - - - - - - - - NULL PPIL4 85313 genome.wustl.edu 37 6 149855846 149855846 + Nonsense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_139126.2 -1 reviewed p.R177* 1.000 199 0% 169 30.2% - - - - - NULL ZNF713 349075 genome.wustl.edu 37 7 56007596 56007596 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_182633.1 +1 provisional p.S397N 0.117 36 0% 70 25.7% - - probably_damaging(0.957) tolerated(0.94) neutral(0.401) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 FBXO24 26261 genome.wustl.edu 37 7 100190467 100190467 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_033506.2 +1 reviewed p.R207Q 1.000 121 0% 119 29.4% - - probably_damaging(0.968) tolerated(0.41) neutral(0.425) NULL HIPK2 28996 genome.wustl.edu 37 7 139281634 139281634 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000263551 -1 known p.P849L 1.000 75 0% 88 21.6% - - benign(0.004) tolerated(0.16) neutral(0.059) NULL CNTNAP2 26047 genome.wustl.edu 37 7 146829379 146829379 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_014141.5 +1 reviewed p.V376I 1.000 167 0% 52 21.2% - - benign(0.351) tolerated(0.54) neutral(0.118) superfamily_Concanavalin A-like lectins/glucanases NOS3 4846 genome.wustl.edu 37 7 150698965 150698965 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000603.4 +1 reviewed p.A520V 0.999 23 0% 29 41.4% - - benign(0.183) tolerated(0.21) neutral(0.061) superfamily_Flavoproteins WWP1 11059 genome.wustl.edu 37 8 87393753 87393753 + Missense_Mutation SNP A A G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_007013.3 +1 validated p.T77A 0.527 98 0% 125 54.4% - - benign(0) tolerated(0.4) neutral(0.016) HMMPfam_C2,HMMSmart_SM00239,superfamily_C2 domain (Calcium/lipid-binding domain CaLB) RGS22 26166 genome.wustl.edu 37 8 100990290 100990290 + Missense_Mutation SNP C C A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_015668.3 -1 validated p.G1125V 1.000 66 0% 91 27.5% - - probably_damaging(1) tolerated(0.25) deleterious(0.537) HMMPfam_RGS,HMMSmart_SM00315,superfamily_Regulator of G-protein signaling RGS CSMD3 114788 genome.wustl.edu 37 8 113331092 113331092 + Missense_Mutation SNP A A G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_198123.1 -1 validated p.M2445T 1.000 174 0% 58 51.7% - - possibly_damaging(0.9) deleterious(0.02) deleterious(0.740) HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain CSMD3 114788 genome.wustl.edu 37 8 113563032 113563032 + Missense_Mutation SNP T T G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_198123.1 -1 validated p.N1478H 1.000 102 0% 23 47.8% - - probably_damaging(0.999) tolerated(0.07) deleterious(0.809) HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain ZNF7 7553 genome.wustl.edu 37 8 146067573 146067573 + Missense_Mutation SNP C C A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_003416.2 +1 validated p.P361T 0.994 61 0% 90 26.7% - - probably_damaging(1) tolerated(0.08) deleterious(0.800) superfamily_SSF57667 HNRNPF 3185 genome.wustl.edu 37 10 43882716 43882716 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001098204.1 -1 reviewed p.R206Q 1.000 72 0% 88 39.8% - - probably_damaging(0.997) deleterious(0.01) deleterious(0.872) NULL ANXA8L2 244 genome.wustl.edu 37 10 47756086 47756086 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001630.2 +1 reviewed p.D182 1.000 234 0% 307 35.8% - - - - - superfamily_Annexin,HMMPfam_Annexin PTEN 5728 genome.wustl.edu 37 10 89692774 89692774 + Frame_Shift_Del DEL A A - novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000371953 +1 known p.Q87fs 1.000 - - - - - - - - - HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II PTEN 5728 genome.wustl.edu 37 10 89692776 89692776 + Missense_Mutation SNP A A C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000371953 +1 known p.Q87P 1.000 191 0% 115 38.3% - - benign(0.172) tolerated(0.27) neutral(0.049) HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II PTEN 5728 genome.wustl.edu 37 10 89712016 89712019 + Frame_Shift_Del DEL AGTA AGTA - novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 AGTA AGTA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000371953 +1 known p.N212fs 1.000 - - - - - - - - - superfamily_C2 domain (Calcium/lipid-binding domain CaLB),HMMPfam_PTEN_C2 MRGPRX3 117195 genome.wustl.edu 37 11 18159108 18159108 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_054031.3 +1 reviewed p.R120H 1.000 230 0% 180 53.9% - - probably_damaging(1) deleterious(0.02) deleterious(0.883) HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like CD82 3732 genome.wustl.edu 37 11 44626624 44626624 + Silent SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_002231.3 +1 reviewed p.S51 0.016 85 0% 91 31.9% - - - - - HMMPfam_Tetraspannin MIR130A 406919 genome.wustl.edu 37 11 57408752 57408752 + RNA SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000385274 +1 known NULL 0.005 88 0% 90 36.7% - - - - - - VPS11 55823 genome.wustl.edu 37 11 118949917 118949918 + Frame_Shift_Del DEL AG AG - novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 AG AG Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000300793 +1 known p.S782fs 1.000:1.000 - - - - - - - - - NULL KCNA1 3736 genome.wustl.edu 37 12 5020637 5020637 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000217.2 +1 reviewed p.D31 0.515 27 0% 19 31.6% - - - - - NULL LRRK2 120892 genome.wustl.edu 37 12 40671965 40671965 + Silent SNP A A C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_198578.3 +1 reviewed p.R715 0.848 248 0% 141 18.4% - - - - - NULL PLEKHA8P1 51054 genome.wustl.edu 37 12 45567898 45567898 + Missense_Mutation SNP A A T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_015899.1 -1 provisional p.M84K 0.989 357 0% 275 57.5% - - - - - NULL KRT80 144501 genome.wustl.edu 37 12 52567476 52567476 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_182507.2 -1 reviewed p.D247N 0.998 18 0% 26 30.8% - - probably_damaging(0.998) tolerated(0.4) deleterious(0.490) HMMPfam_Filament OR6C1 390321 genome.wustl.edu 37 12 55714897 55714897 + Missense_Mutation SNP A A G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001005182.1 +1 provisional p.I172V 0.416 164 0% 58 48.3% - - benign(0) tolerated(0.16) neutral(0.059) HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like BAZ2A 11176 genome.wustl.edu 37 12 56998974 56998974 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_013449.3 -1 validated p.L879 0.993 80 0% 72 56.9% - - - - - HMMPfam_DDT,HMMSmart_SM00571 LRRIQ1 84125 genome.wustl.edu 37 12 85518131 85518131 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001079910.1 +1 validated p.A1281T 0.039 85 0% 49 59.2% - - benign(0.001) tolerated(0.06) neutral(0.323) NULL MYBPC1 4604 genome.wustl.edu 37 12 102040659 102040659 + Missense_Mutation SNP G G A rs190129005 by1000genomes TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_002465.2 +1 validated p.V362I 1.000 153 0% 132 23.5% - - probably_damaging(0.999) tolerated(0.05) deleterious(0.836) HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin RXFP2 122042 genome.wustl.edu 37 13 32313752 32313752 + Missense_Mutation SNP G G T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_130806.3 +1 reviewed p.M1I 0.000 299 0% 96 28.1% - - benign(0.002) deleterious(0) neutral(0.445) NULL ITGA11 22801 genome.wustl.edu 37 15 68650900 68650900 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001004439.1 -1 reviewed p.V166I 0.767 167 0% 108 12% - - benign(0.015) tolerated(0.07) neutral(0.320) HMMPfam_VWA,HMMSmart_SM00327,superfamily_vWA-like,superfamily_Integrin alpha N-terminal domain ROGDI 79641 genome.wustl.edu 37 16 4848647 4848647 + Nonsense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_024589.1 -1 provisional p.Q152* 1.000 67 0% 112 49.1% - - - - - HMMPfam_Rogdi_lz ABAT 18 genome.wustl.edu 37 16 8862739 8862739 + Missense_Mutation SNP A A T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000663.4 +1 reviewed p.D242V 1.000 82 0% 111 22.5% - - benign(0.334) deleterious(0.02) deleterious(0.488) HMMPfam_Aminotran_3,superfamily_PyrdxlP-dep_Trfase_major SMG1 23049 genome.wustl.edu 37 16 18866018 18866018 + Silent SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_015092.4 -1 reviewed p.P1481 0.998 151 0% 184 45.1% - - - - - superfamily_ARM repeat ZNF469 84627 genome.wustl.edu 37 16 88502965 88502965 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001127464.1 +1 reviewed p.D3001 0.000 16 0% 13 53.8% - - - - - NULL ACAP1 9744 genome.wustl.edu 37 17 7252365 7252365 + Missense_Mutation SNP G G A rs192044976 by1000genomes TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_014716.3 +1 validated p.R577Q 1.000 84 0% 122 87.7% - - benign(0) tolerated(0.19) neutral(0.050) NULL TP53 7157 genome.wustl.edu 37 17 7577538 7577538 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000546.4 -1 reviewed p.R248Q 1.000 100 0% 122 88.5% - - probably_damaging(1) deleterious(0.01) deleterious(0.905) PatternScan_P53,superfamily_p53-like transcription factors,HMMPfam_P53 MYO1D 4642 genome.wustl.edu 37 17 31107648 31107648 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_015194.1 -1 provisional p.A84T 1.000 171 0% 136 41.2% - - probably_damaging(1) tolerated(0.29) deleterious(0.529) HMMPfam_Myosin_head,HMMSmart_SM00242,superfamily_P-loop containing nucleoside triphosphate hydrolases HIGD1B 51751 genome.wustl.edu 37 17 42925565 42925565 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_016438.2 +1 provisional p.D15 0.358 83 0% 127 20.5% - - - - - HMMPfam_HIG_1_N ZBTB7C 201501 genome.wustl.edu 37 18 45567247 45567247 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_001039360.1 -1 validated p.D78N 1.000 174 0% 226 22.1% - - possibly_damaging(0.945) deleterious(0.01) deleterious(0.795) HMMSmart_SM00225,superfamily_POZ domain,HMMPfam_BTB KRI1 65095 genome.wustl.edu 37 19 10670340 10670340 + Silent SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_023008.3 -1 validated p.K330 1.000 198 0% 416 13.9% - - - - - NULL ZNF792 126375 genome.wustl.edu 37 19 35449397 35449397 + Missense_Mutation SNP C C A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_175872.4 -1 validated p.E454D 0.030 119 0% 150 19.3% - - possibly_damaging(0.849) tolerated(0.1) deleterious(0.613) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers CIC 23152 genome.wustl.edu 37 19 42798378 42798378 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_015125.3 +1 validated p.R1417C 1.000 54 0% 109 41.3% - - probably_damaging(0.999) deleterious(0.03) deleterious(0.855) NULL FASTKD5 60493 genome.wustl.edu 37 20 3127732 3127732 + Missense_Mutation SNP G G C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_021826.4 -1 validated p.A662G 0.143 42 0% 52 53.8% - - benign(0) tolerated(0.07) neutral(0.319) NULL C20orf152 140894 genome.wustl.edu 37 20 34572558 34572558 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_080834.1 +1 predicted p.V192I 0.921 177 0% 225 15.6% - - benign(0) tolerated(0.45) neutral(0.012) HMMPfam_cNMP_binding,HMMSmart_cNMP,superfamily_cNMP_binding KRTAP10-5 386680 genome.wustl.edu 37 21 46000080 46000080 + Missense_Mutation SNP A A G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_198694.2 -1 reviewed p.C126R 0.149 231 0% 284 23.9% - - unknown(0) tolerated(0.09) - NULL ITGB2 3689 genome.wustl.edu 37 21 46306688 46306688 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_000211.3 -1 reviewed p.R737H 0.997 49 0% 59 50.8% - - benign(0.303) deleterious(0.02) deleterious(0.477) HMMPfam_Integrin_b_cyt MEI1 150365 genome.wustl.edu 37 22 42172114 42172114 + Missense_Mutation SNP C C G novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_152513.3 +1 validated p.I851M 1.000 161 0% 166 20.5% - - possibly_damaging(0.577) deleterious(0.01) deleterious(0.604) NULL PLXNB2 23654 genome.wustl.edu 37 22 50720089 50720089 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_012401.2 -1 validated p.T1143M 0.988 23 0% 29 72.4% - - probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL ENSG00000210082 0 genome.wustl.edu 37 MT 2702 2702 + RNA SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000387347 +1 known NULL NULL 14 0% 21 81% - - - - - - ENSG00000198888 0 genome.wustl.edu 37 MT 3535 3535 + Silent SNP T T C novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 ENST00000361390 +1 known p.L77 NULL 3 0.000 9 1.000 - - - - - HMMPfam_NADHdh FAM9A 171482 genome.wustl.edu 37 X 8763373 8763373 + Missense_Mutation SNP C C T novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_174951.3 -1 validated p.E193K 0.005 286 0% 249 30.1% - - unknown(0) - - NULL OTUD6A 139562 genome.wustl.edu 37 X 69283005 69283005 + Missense_Mutation SNP G G A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_207320.1 +1 provisional p.V211M 0.030 37 0% 35 31.4% - - probably_damaging(0.97) tolerated(0.06) deleterious(0.735) HMMPfam_OTU,superfamily_SSF54001 MAGEC2 51438 genome.wustl.edu 37 X 141291033 141291033 + Missense_Mutation SNP C C A novel TCGA-BG-A0YV-01A-11D-A10M-09 TCGA-BG-A0YV-10A-01D-A10M-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 302690ee-ca13-4267-8079-74865d572b3a 479f2f83-5a24-4cb4-bfd8-41c5e5932060 NM_016249.3 -1 reviewed p.E247D 0.004 156 0% 139 31.7% - - possibly_damaging(0.685) tolerated(0.08) deleterious(0.544) HMMPfam_MAGE