Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RP11-377D9.3	0	broad.mit.edu	37	12	13154542	13154542	+	RNA	SNP	C	C	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr12:13154542C>A	ENST00000543321.1	+	0	31				HTR7P1_ENST00000535469.1_RNA																							GACGGTGGCGCCGAACCGGTC	0.746000													2	0					1	1	1	1	0
KRAS	3845	broad.mit.edu	37	12	25398285	25398285	+	Missense_Mutation	SNP	C	C	A	rs121913530		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr12:25398285C>A	ENST00000311936.3	-	2	225	c.34G>T	c.(34-36)Ggt>Tgt	p.G12C	KRAS_ENST00000256078.4_Missense_Mutation_p.G12C|KRAS_ENST00000557334.1_Missense_Mutation_p.G12C|KRAS_ENST00000556131.1_Missense_Mutation_p.G12C	NM_004985.3	NP_004976.2	P01116	RASK_HUMAN	Kirsten rat sarcoma viral oncogene homolog	12			G -> A (in a colorectal cancer sample; somatic mutation).|G -> C (in lung carcinoma; somatic mutation).|G -> D (in pancreatic carcinoma, GASC and lung carcinoma; somatic mutation).|G -> R (in lung cancer and bladder cancer; somatic mutation).|G -> S (in lung carcinoma and GASC; somatic mutation).|G -> V (in lung carcinoma, pancreatic carcinoma, colon cancer and GASC; somatic mutation).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	plasma membrane	GTP binding|GTPase activity|protein binding	p.G12C(3001)|p.G12S(1288)|p.G12R(789)|p.G12F(46)|p.G12L(8)|p.G12I(4)|p.G12W(3)|p.A11_G12insGA(2)|p.G12Y(2)|p.G12N(1)	UBE2L3/KRAS(2)	NS(6)|adrenal_gland(1)|autonomic_ganglia(3)|biliary_tract(532)|bone(2)|breast(32)|central_nervous_system(14)|cervix(50)|endometrium(411)|eye(4)|gastrointestinal_tract_(site_indeterminate)(7)|genital_tract(1)|haematopoietic_and_lymphoid_tissue(385)|kidney(8)|large_intestine(15267)|liver(29)|lung(3407)|oesophagus(16)|ovary(612)|pancreas(3739)|penis(1)|peritoneum(6)|prostate(96)|salivary_gland(6)|skin(45)|small_intestine(68)|soft_tissue(88)|stomach(207)|testis(17)|thymus(5)|thyroid(159)|upper_aerodigestive_tract(68)|urinary_tract(57)	25349	all_cancers(2;1e-35)|all_epithelial(2;1.97e-38)|all_lung(3;2.1e-23)|Lung NSC(3;1.16e-22)|Acute lymphoblastic leukemia(6;0.00231)|all_hematologic(7;0.00259)|Melanoma(3;0.0301)|Colorectal(261;0.11)|Ovarian(17;0.12)		OV - Ovarian serous cystadenocarcinoma(3;1.23e-21)|Epithelial(3;1.31e-20)|all cancers(3;5.45e-18)|STAD - Stomach adenocarcinoma(2;2.68e-05)			CCTACGCCACCAGCTCCAACT	0.348000	G12C(CALU1_LUNG)|G12C(HCC44_LUNG)|G12C(IALM_LUNG)|G12C(KHM1B_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12C(KYSE410_OESOPHAGUS)|G12C(LU65_LUNG)|G12C(LU99_LUNG)|G12C(MIAPACA2_PANCREAS)|G12C(NCIH1373_LUNG)|G12C(NCIH1792_LUNG)|G12C(NCIH2030_LUNG)|G12C(NCIH2122_LUNG)|G12C(NCIH23_LUNG)|G12C(NCIH358_LUNG)|G12C(OV56_OVARY)|G12C(SW1463_LARGE_INTESTINE)|G12C(SW1573_LUNG)|G12C(SW837_LARGE_INTESTINE)|G12C(UMUC3_URINARY_TRACT)|G12R(CAL62_THYROID)|G12R(HS274T_BREAST)|G12R(HUPT3_PANCREAS)|G12R(KP2_PANCREAS)|G12R(PSN1_PANCREAS)|G12R(TCCPAN2_PANCREAS)|G12S(A549_LUNG)|G12S(KMS20_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12S(LS123_LARGE_INTESTINE)	119	Mis		"""pancreatic, colorectal, lung, thyroid, AML, others"""				Noonan syndrome;Cardiofaciocutaneous syndrome	TSP Lung(1;<1E-08)|Multiple Myeloma(2;<1E-6)			10	3					2.17888e-05	2.51045e-05	1	1	0
HCN4	10021	broad.mit.edu	37	15	73616239	73616239	+	Missense_Mutation	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr15:73616239C>T	ENST00000261917.3	-	8	3188	c.2195G>A	c.(2194-2196)gGc>gAc	p.G732D		NM_005477.2	NP_005468.1	Q9Y3Q4	HCN4_HUMAN	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	732					blood circulation|muscle contraction	integral to membrane	cAMP binding|protein binding|sodium channel activity|voltage-gated potassium channel activity			NS(2)|biliary_tract(1)|breast(1)|endometrium(4)|kidney(1)|large_intestine(13)|liver(1)|lung(18)|ovary(6)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	55				COAD - Colon adenocarcinoma(1;0.142)		GTTGAAGACGCCGGAGTTGAG	0.597000													22	30					0	0	1	0	0
PHC1	1911	broad.mit.edu	37	12	9075367	9075367	+	Missense_Mutation	SNP	C	C	G			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr12:9075367C>G	ENST00000433083.2	+	5	605	c.460C>G	c.(460-462)Cat>Gat	p.H154D	PHC1_ENST00000543824.1_Missense_Mutation_p.H199D|PHC1_ENST00000433847.2_3'UTR|PHC1_ENST00000536844.1_5'UTR|PHC1_ENST00000544916.1_Missense_Mutation_p.H199D			P78364	PHC1_HUMAN	polyhomeotic homolog 1 (Drosophila)	199					multicellular organismal development	PcG protein complex	DNA binding|zinc ion binding	p.H199Y(2)		breast(2)|cervix(1)|endometrium(5)|large_intestine(8)|liver(2)|lung(3)|ovary(2)|pancreas(1)|skin(2)|upper_aerodigestive_tract(1)	27						TCCTGGAGTTCATGCAGATGC	0.592000													9	9					0	0	1	0	0
MRPS11	64963	broad.mit.edu	37	15	89021195	89021195	+	Silent	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr15:89021195G>A	ENST00000325844.4	+	6	835	c.570G>A	c.(568-570)aaG>aaA	p.K190K	MRPS11_ENST00000353598.6_Silent_p.K157K	NM_022839.3	NP_073750.2	P82912	RT11_HUMAN	mitochondrial ribosomal protein S11	190					DNA damage response, detection of DNA damage|translation	mitochondrial small ribosomal subunit	structural constituent of ribosome			large_intestine(3)	3	Lung NSC(78;0.203)		BRCA - Breast invasive adenocarcinoma(143;0.188)			GCCCCAGGAAGGCTCGGAAGC	0.587000													38	31					0	0	1	0	0
AMOT	154796	broad.mit.edu	37	X	112022454	112022454	+	Silent	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chrX:112022454C>T	ENST00000371959.3	-	10	2927	c.2928G>A	c.(2926-2928)ccG>ccA	p.P976P	AMOT_ENST00000304758.1_Silent_p.P567P|AMOT_ENST00000524145.1_Silent_p.P976P|AMOT_ENST00000371962.1_Silent_p.P744P	NM_001113490.1	NP_001106962.1	Q4VCS5	AMOT_HUMAN	angiomotin	976					actin cytoskeleton organization|cell-cell junction assembly|negative regulation of angiogenesis|negative regulation of vascular permeability|positive regulation of blood vessel endothelial cell migration|positive regulation of cell size|positive regulation of stress fiber assembly|regulation of cell migration	actin filament|cell surface|cytoplasm|endocytic vesicle|external side of plasma membrane|integral to membrane|lamellipodium|ruffle|stress fiber|tight junction	angiostatin binding|protein binding|receptor activity			breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(25)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)	43						GAACTGGAGCCGGAGCAGCTG	0.627000													9	8					0	0	1	0	0
DLGAP4	22839	broad.mit.edu	37	20	35061024	35061024	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr20:35061024G>A	ENST00000373913.3	+	3	1384	c.904G>A	c.(904-906)Gcc>Acc	p.A302T	DLGAP4_ENST00000339266.5_Missense_Mutation_p.A302T|DLGAP4_ENST00000373907.2_Missense_Mutation_p.A302T|DLGAP4_ENST00000401952.2_Missense_Mutation_p.A302T			Q9Y2H0	DLGP4_HUMAN	discs, large (Drosophila) homolog-associated protein 4	302					cell-cell signaling	membrane	protein binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(3)|lung(20)|ovary(2)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)	37	Breast(12;0.0192)	Myeloproliferative disorder(115;0.00878)				CCTCAGCCACGCCCACGAGGT	0.637000													4	17					0	0	1	0	0
FAM86DP	0	broad.mit.edu	37	3	75475709	75475709	+	RNA	SNP	T	T	C			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr3:75475709T>C	ENST00000459803.1	-	0	820					NR_024241.1													p.I261V(1)									CTCCGCAGGATCCCGACCAGC	0.562000													3	42					0	0	1	0	0
EPHA5	2044	broad.mit.edu	37	4	66218763	66218763	+	Missense_Mutation	SNP	C	C	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr4:66218763C>A	ENST00000273854.3	-	13	2895	c.2295G>T	c.(2293-2295)ttG>ttT	p.L765F	EPHA5_ENST00000511294.1_Missense_Mutation_p.L766F|EPHA5_ENST00000354839.4_Missense_Mutation_p.L743F|EPHA5_ENST00000432638.2_Missense_Mutation_p.L602F	NM_004439.5	NP_004430.4	P54756	EPHA5_HUMAN	EPH receptor A5	765	Protein kinase.				cAMP-mediated signaling|neuron development	dendrite|external side of plasma membrane|integral to plasma membrane|neuronal cell body|perinuclear region of cytoplasm|rough endoplasmic reticulum	ATP binding|transmembrane-ephrin receptor activity			autonomic_ganglia(1)|breast(2)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(25)|liver(1)|lung(76)|ovary(3)|pancreas(1)|prostate(1)|skin(3)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	142						ATCCTACCTTCAAAAATGTAT	0.358000										TSP Lung(17;0.13)			9	13					0.00621372	0.00672096	1	1	0
ANKRD6	22881	broad.mit.edu	37	6	90276788	90276788	+	Missense_Mutation	SNP	C	C	G			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr6:90276788C>G	ENST00000369408.5	+	2	442	c.93C>G	c.(91-93)aaC>aaG	p.N31K	ANKRD6_ENST00000339746.4_Missense_Mutation_p.N31K|ANKRD6_ENST00000522441.1_Missense_Mutation_p.N31K|ANKRD6_ENST00000485637.1_Missense_Mutation_p.N31K|ANKRD6_ENST00000447838.2_Missense_Mutation_p.N31K|ANKRD6_ENST00000520793.1_Missense_Mutation_p.N31K|ANKRD6_ENST00000520886.2_Intron	NM_001242813.1	NP_001229742.1	Q9Y2G4	ANKR6_HUMAN	ankyrin repeat domain 6	31							protein binding			NS(1)|endometrium(3)|large_intestine(7)|lung(3)|ovary(3)|pancreas(1)|prostate(1)|stomach(2)	21		all_cancers(76;1.22e-09)|Prostate(29;1.16e-10)|Acute lymphoblastic leukemia(125;1.49e-10)|all_hematologic(105;7.79e-07)|all_epithelial(107;1.83e-05)|Lung NSC(302;0.239)		BRCA - Breast invasive adenocarcinoma(108;0.0209)		AGCTCATCAACAAGGGCGCCA	0.502000													6	9					0	0	1	0	0
SLC11A1	6556	broad.mit.edu	37	2	219249939	219249939	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:219249939G>A	ENST00000233202.6	+	4	683	c.343G>A	c.(343-345)Gtg>Atg	p.V115M	SLC11A1_ENST00000539932.1_5'UTR|SLC11A1_ENST00000473367.1_3'UTR	NM_000578.3	NP_000569.3	P49279	NRAM1_HUMAN	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	115					activation of protein kinase activity|antigen processing and presentation of peptide antigen|cadmium ion transmembrane transport|cellular cadmium ion homeostasis|cellular iron ion homeostasis|defense response to Gram-negative bacterium|defense response to protozoan|divalent metal ion export|inflammatory response|interleukin-2 production|interleukin-3 production|iron ion transport|L-arginine import|macrophage activation|MHC class II biosynthetic process|mRNA stabilization|multicellular organismal iron ion homeostasis|negative regulation of cytokine production|nitrite transport|phagocytosis|positive regulation of dendritic cell antigen processing and presentation|positive regulation of interferon-gamma production|positive regulation of phagocytosis|positive regulation of T-helper 1 type immune response|positive regulation of transcription from RNA polymerase II promoter|respiratory burst|response to interferon-gamma|response to lipopolysaccharide|T cell cytokine production|T cell proliferation involved in immune response|vacuolar acidification|wound healing	integral to plasma membrane|late endosome membrane|lysosome|phagocytic vesicle membrane|tertiary granule membrane	manganese ion transmembrane transporter activity|metal ion:hydrogen antiporter activity|protein homodimerization activity	p.V115M(2)		NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(3)|ovary(3)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)	19		Renal(207;0.0474)		Epithelial(149;1.16e-06)|all cancers(144;0.000195)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		ACGTCTGGGCGTGGTGACAGG	0.632000													41	112					0	0	1	0	0
POTED	317754	broad.mit.edu	37	21	15011886	15011886	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr21:15011886G>A	ENST00000299443.5	+	10	1512	c.1460G>A	c.(1459-1461)gGa>gAa	p.G487E		NM_174981.3|NM_207355.2	NP_778146.2|NP_997238.2	Q86YR6	POTED_HUMAN	POTE ankyrin domain family, member D	487						plasma membrane		p.G487E(1)		central_nervous_system(1)|large_intestine(10)|liver(2)|lung(8)|ovary(4)|pancreas(1)|prostate(1)|skin(5)|stomach(1)	33						CAGAACACTGGAATATCACAA	0.323000													3	30					0	0	1	0	0
ZNF638	27332	broad.mit.edu	37	2	71582903	71582903	+	Missense_Mutation	SNP	C	C	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:71582903C>A	ENST00000409544.1	+	3	2002	c.1372C>A	c.(1372-1374)Cgt>Agt	p.R458S	ZNF638_ENST00000377802.2_Missense_Mutation_p.R458S|ZNF638_ENST00000355812.3_Missense_Mutation_p.R458S|ZNF638_ENST00000264447.4_Missense_Mutation_p.R458S|ZNF638_ENST00000410075.1_3'UTR	NM_001252612.1	NP_001239541.1	Q14966	ZN638_HUMAN	zinc finger protein 638	458					RNA splicing	cytoplasm|nuclear speck	double-stranded DNA binding|nucleotide binding|RNA binding|zinc ion binding			breast(4)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(16)|lung(28)|ovary(2)|pancreas(2)|prostate(1)|skin(2)|urinary_tract(1)	63						TCGACAGTTACGTCAACAGTA	0.284000													3	7					0.115264	0.117481	1	1	0
THBS2	7058	broad.mit.edu	37	6	169626326	169626326	+	Silent	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr6:169626326G>A	ENST00000366787.3	-	17	2736	c.2487C>T	c.(2485-2487)gaC>gaT	p.D829D	XXyac-YX65C7_A.2_ENST00000444188.1_RNA	NM_003247.2	NP_003238.2	P35442	TSP2_HUMAN	thrombospondin 2	829					cell adhesion	extracellular region	calcium ion binding|heparin binding|protein binding|structural molecule activity			NS(3)|biliary_tract(1)|endometrium(8)|kidney(3)|large_intestine(23)|liver(1)|lung(56)|ovary(6)|prostate(1)|skin(3)|stomach(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	111		Breast(66;1.78e-05)|Ovarian(120;0.0728)|Esophageal squamous(34;0.247)		OV - Ovarian serous cystadenocarcinoma(33;1.85e-21)|BRCA - Breast invasive adenocarcinoma(81;1.43e-06)|GBM - Glioblastoma multiforme(31;0.000379)		CCCCCACACCGTCACCATCCG	0.542000													46	49					0	0	1	0	0
CYP2D7P1	0	broad.mit.edu	37	22	42538732	42538732	+	RNA	SNP	C	C	A	rs4992865		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr22:42538732C>A	ENST00000358097.4	-	0	587				CYP2D7P1_ENST00000433992.1_RNA																endometrium(1)	1						CACCCACCGGCTTGGTCGGCG	0.682000													4	1					0.0293803	0.0305325	1	1	0
NPC2	10577	broad.mit.edu	37	14	74951225	74951225	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr14:74951225G>A	ENST00000541064.1	-	3	262	c.256C>T	c.(256-258)Ccc>Tcc	p.P86S	NPC2_ENST00000238633.2_Missense_Mutation_p.P86S|NPC2_ENST00000434013.2_Missense_Mutation_p.P86S|NPC2_ENST00000557510.1_Missense_Mutation_p.P86S|NPC2_ENST00000555619.1_Missense_Mutation_p.P86S			P61916	NPC2_HUMAN	Niemann-Pick disease, type C2	86			P -> L (in dbSNP:rs4688).		cholesterol efflux|cholesterol homeostasis|glycolipid transport|intracellular cholesterol transport|phospholipid transport|regulation of isoprenoid metabolic process|response to virus	extracellular region|lysosome	cholesterol binding|enzyme binding			breast(1)|endometrium(2)|large_intestine(1)|lung(1)|upper_aerodigestive_tract(2)	7				BRCA - Breast invasive adenocarcinoma(234;0.00149)		TCAGGAATGGGAAAGGGAACT	0.433000													37	52					0	0	1	0	0
TTLL3	26140	broad.mit.edu	37	3	9874913	9874913	+	Missense_Mutation	SNP	G	G	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr3:9874913G>T	ENST00000547186.1	+	11	1896	c.1680G>T	c.(1678-1680)caG>caT	p.Q560H	TTLL3_ENST00000426895.4_Missense_Mutation_p.Q703H|TTLL3_ENST00000397241.1_Intron|TTLL3_ENST00000455274.1_Intron|TTLL3_ENST00000427853.3_Intron|TTLL3_ENST00000430793.1_Missense_Mutation_p.Q348H|ARPC4-TTLL3_ENST00000397256.1_Intron|TTLL3_ENST00000383827.1_Intron	NM_001025930.3	NP_001021100.3	Q9Y4R7	TTLL3_HUMAN	tubulin tyrosine ligase-like family, member 3	560					axoneme assembly|cilium assembly|protein polyglycylation	cilium axoneme|cytoplasm|microtubule	protein-glycine ligase activity, initiating|tubulin-tyrosine ligase activity			central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(10)|ovary(1)|prostate(2)|skin(1)	26	Medulloblastoma(99;0.227)					TGCTGACCCAGCGAGGCTCTG	0.647000													11	23					4.68919e-08	5.52282e-08	1	1	0
FUCA1	2517	broad.mit.edu	37	1	24175172	24175172	+	Missense_Mutation	SNP	C	C	T	rs145603001	byFrequency	TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:24175172C>T	ENST00000374479.3	-	6	1134	c.1127G>A	c.(1126-1128)cGg>cAg	p.R376Q		NM_000147.4	NP_000138.2	P04066	FUCO_HUMAN	fucosidase, alpha-L- 1, tissue	376					fucose metabolic process|glycosaminoglycan catabolic process	lysosome	alpha-L-fucosidase activity|cation binding			breast(1)|endometrium(1)|large_intestine(3)|lung(3)	8		Colorectal(325;3.46e-05)|Renal(390;0.000219)|Lung NSC(340;0.000233)|all_lung(284;0.000321)|Ovarian(437;0.00348)|Breast(348;0.00957)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|OV - Ovarian serous cystadenocarcinoma(117;1.11e-24)|Colorectal(126;5.69e-08)|COAD - Colon adenocarcinoma(152;3.15e-06)|GBM - Glioblastoma multiforme(114;9.04e-06)|BRCA - Breast invasive adenocarcinoma(304;0.000986)|KIRC - Kidney renal clear cell carcinoma(1967;0.00342)|STAD - Stomach adenocarcinoma(196;0.0128)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.144)		CCATTGCACCCGCCATGGTTT	0.478000													10	20					0	0	1	0	0
SREBF2	6721	broad.mit.edu	37	22	42299024	42299024	+	Silent	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr22:42299024C>T	ENST00000361204.4	+	17	3124	c.2958C>T	c.(2956-2958)ctC>ctT	p.L986L	SREBF2_ENST00000491541.1_3'UTR	NM_004599.2	NP_004590.2	Q12772	SRBP2_HUMAN	sterol regulatory element binding transcription factor 2	986					cholesterol metabolic process	ER to Golgi transport vesicle membrane|Golgi membrane|nucleus|SREBP-SCAP-Insig complex	protein C-terminus binding			NS(2)|breast(6)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(9)|ovary(1)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	38						GGACAGCGCTCTGGCAAAAAC	0.657000													4	0					0	0	1	0	0
PTP4A3	11156	broad.mit.edu	37	8	142441037	142441037	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr8:142441037G>A	ENST00000520105.1	+	5	1283	c.340G>A	c.(340-342)Gga>Aga	p.G114R	PTP4A3_ENST00000524028.1_Missense_Mutation_p.G53R|PTP4A3_ENST00000349124.1_Missense_Mutation_p.G114R|PTP4A3_ENST00000521578.1_Missense_Mutation_p.G139R|PTP4A3_ENST00000329397.1_Missense_Mutation_p.G139R			O75365	TP4A3_HUMAN	protein tyrosine phosphatase type IVA, member 3	139	Tyrosine-protein phosphatase.					early endosome|plasma membrane	identical protein binding|prenylated protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			endometrium(2)|large_intestine(1)|lung(3)	6	all_cancers(97;2.55e-15)|all_epithelial(106;1.39e-13)|Lung NSC(106;2.07e-05)|all_lung(105;2.89e-05)|Ovarian(258;0.0303)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0474)			GAAGCGCCGCGGAGCCATCAA	0.597000													15	17					0	0	1	0	0
TONSL	4796	broad.mit.edu	37	8	145661426	145661426	+	Missense_Mutation	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr8:145661426C>T	ENST00000409379.3	-	17	2419	c.2390G>A	c.(2389-2391)cGg>cAg	p.R797Q	AC084125.4_ENST00000544423.1_RNA	NM_013432.4	NP_038460.4	Q96HA7	TONSL_HUMAN	tonsoku-like, DNA repair protein	797					cytoplasmic sequestering of transcription factor|double-strand break repair via homologous recombination|replication fork processing	cytoplasm|nuclear replication fork	histone binding|transcription corepressor activity			biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(2)|lung(14)|ovary(3)|prostate(1)|skin(1)	26						GCCCACACCCCGGATGGCTGC	0.726000													11	2					0	0	1	0	0
L1CAM	3897	broad.mit.edu	37	X	153131272	153131272	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chrX:153131272G>A	ENST00000370060.1	-	20	2623	c.2434C>T	c.(2434-2436)Ccc>Tcc	p.P812S	L1CAM_ENST00000370057.3_Missense_Mutation_p.P812S|L1CAM_ENST00000361699.4_Missense_Mutation_p.P812S|L1CAM_ENST00000543994.1_Missense_Mutation_p.P814S|L1CAM_ENST00000538883.1_Missense_Mutation_p.P814S|L1CAM_ENST00000370055.1_Missense_Mutation_p.P807S|L1CAM_ENST00000361981.3_Missense_Mutation_p.P807S	NM_001278116.1	NP_001265045.1	P32004	L1CAM_HUMAN	L1 cell adhesion molecule	812	Fibronectin type-III 3.				axon guidance|blood coagulation|cell death|leukocyte migration	integral to membrane				NS(1)|breast(4)|central_nervous_system(3)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(5)|liver(1)|lung(31)|ovary(13)|pancreas(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	81	all_cancers(53;6.72e-15)|all_epithelial(53;3.19e-09)|all_lung(58;3.39e-06)|all_hematologic(71;4.25e-06)|Lung NSC(58;4.7e-06)|Acute lymphoblastic leukemia(192;6.56e-05)					ATTGCCTGGGGGTCTGGAAAC	0.592000													50	55					0	0	1	0	0
CASQ1	844	broad.mit.edu	37	1	160168791	160168791	+	Missense_Mutation	SNP	C	C	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:160168791C>A	ENST00000368079.3	+	9	1189	c.914C>A	c.(913-915)aCt>aAt	p.T305N	CASQ1_ENST00000467691.1_Missense_Mutation_p.T32N|CASQ1_ENST00000368078.3_Missense_Mutation_p.T311N	NM_001231.4	NP_001222.3	P31415	CASQ1_HUMAN	calsequestrin 1 (fast-twitch, skeletal muscle)	311						mitochondrial matrix|sarcoplasmic reticulum lumen|smooth endoplasmic reticulum	calcium ion binding			breast(1)|central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(9)|ovary(1)|skin(1)	21	all_cancers(52;2.56e-18)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)			CAAGATAACACTGAAAACCCA	0.502000													19	31					5.03518e-11	6.20616e-11	1	1	0
AKR1C3	8644	broad.mit.edu	37	10	5144364	5144364	+	Silent	SNP	T	T	C			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr10:5144364T>C	ENST00000380554.3	+	6	1294	c.642T>C	c.(640-642)gtT>gtC	p.V214V	AKR1C3_ENST00000605149.1_Silent_p.V191V|AKR1C3_ENST00000439082.2_Silent_p.V95V	NM_001253908.1|NM_003739.5	NP_001240837.1|NP_003730.4	P42330	AK1C3_HUMAN	aldo-keto reductase family 1, member C3	214					prostaglandin metabolic process	cytoplasm	aldo-keto reductase (NADP) activity|androsterone dehydrogenase (A-specific) activity|indanol dehydrogenase activity|prostaglandin-F synthase activity|testosterone 17-beta-dehydrogenase (NAD+) activity|testosterone 17-beta-dehydrogenase (NADP+) activity|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity			breast(2)|central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(6)|skin(1)	14					Dimethyl sulfoxide(DB01093)|NADH(DB00157)	TTGTTCTGGTTGCCTATAGTG	0.383000													20	30					0	0	1	0	0
WASH3P	0	broad.mit.edu	37	15	102506314	102506314	+	RNA	SNP	C	C	G			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr15:102506314C>G	ENST00000557932.1	+	0	60																				central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						CCTGGCAGGTCAGACCTATGC	0.647000													3	6					0	0	1	0	0
TP53	7157	broad.mit.edu	37	17	7578556	7578556	+	Splice_Site	SNP	T	T	G			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr17:7578556T>G	ENST00000420246.2	-	5	508		c.e5-2		TP53_ENST00000455263.2_Splice_Site|TP53_ENST00000269305.4_Splice_Site|TP53_ENST00000445888.2_Splice_Site|TP53_ENST00000413465.2_Splice_Site|TP53_ENST00000359597.4_Splice_Site	NM_001126114.2|NM_001276696.1	NP_001119586.1|NP_001263625.1	P04637	P53_HUMAN	tumor protein p53						activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.?(34)|p.0?(8)|p.V73fs*9(1)|p.Y126fs*11(1)|p.P13fs*18(1)|p.T125_Y126insX(1)		NS(16)|adrenal_gland(37)|autonomic_ganglia(16)|biliary_tract(273)|bone(108)|breast(2530)|central_nervous_system(1264)|cervix(68)|endometrium(223)|eye(24)|fallopian_tube(1)|gastrointestinal_tract_(site_indeterminate)(1)|genital_tract(16)|haematopoietic_and_lymphoid_tissue(1301)|kidney(96)|large_intestine(5124)|liver(897)|lung(2388)|meninges(5)|oesophagus(1473)|ovary(1659)|pancreas(452)|penis(10)|peritoneum(33)|pituitary(4)|placenta(1)|pleura(3)|prostate(235)|salivary_gland(43)|skin(791)|small_intestine(14)|soft_tissue(220)|stomach(1158)|testis(11)|thymus(21)|thyroid(54)|upper_aerodigestive_tract(2271)|urinary_tract(1259)|vagina(6)|vulva(79)	24185		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		AGGGGAGTACTGTAGGAAGAG	0.552000		111	"""Mis, N, F"""		"""breast, colorectal, lung, sarcoma, adrenocortical, glioma, multiple other tumour types"""	"""breast, sarcoma, adrenocortical carcinoma, glioma, multiple other tumour types"""		Other conserved DNA damage response genes	Osteosarcoma, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Breast-Ovarian Cancer, non-BRCA1/2;Hereditary Adrenocortical Cancer;Endometrial Cancer, Familial Clustering of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			23	3					0	0	1	0	0
CYP2D7P1	0	broad.mit.edu	37	22	42538733	42538733	+	RNA	SNP	T	T	G	rs4992864		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr22:42538733T>G	ENST00000358097.4	-	0	586				CYP2D7P1_ENST00000433992.1_RNA																endometrium(1)	1						ACCCACCGGCTTGGTCGGCGA	0.682000													4	1					0	0	1	0	0
TRAPPC11	60684	broad.mit.edu	37	4	184606530	184606530	+	Missense_Mutation	SNP	T	T	G			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr4:184606530T>G	ENST00000334690.6	+	17	1938	c.1736T>G	c.(1735-1737)aTa>aGa	p.I579R	TRAPPC11_ENST00000357207.4_Missense_Mutation_p.I579R|TRAPPC11_ENST00000512476.1_Missense_Mutation_p.I185R	NM_021942.5	NP_068761.4	Q7Z392	CD041_HUMAN	trafficking protein particle complex 11	579																	ATTTTCACAATAGGAGTACAG	0.408000													47	43					0	0	1	0	0
MUC5AC	4586	broad.mit.edu	37	11	1155683	1155683	+	Silent	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr11:1155683G>A	ENST00000356191.2	+	5	369	c.369G>A	c.(367-369)ccG>ccA	p.P123P						mucin 5AC, oligomeric mucus/gel-forming									p.R124L(1)		NS(1)|breast(2)|central_nervous_system(7)|cervix(2)|endometrium(36)|haematopoietic_and_lymphoid_tissue(5)|kidney(9)|large_intestine(19)|liver(1)|lung(89)|ovary(7)|prostate(8)|skin(9)|stomach(1)|upper_aerodigestive_tract(6)|urinary_tract(1)	203		all_cancers(49;2.94e-05)|Breast(177;0.00257)|all_epithelial(84;0.00314)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		BRCA - Breast invasive adenocarcinoma(625;0.00146)|Lung(200;0.0612)|LUSC - Lung squamous cell carcinoma(625;0.0724)		CAGCTACGCCGCAGCCAGGAG	0.637000													27	2					0	0	1	0	0
PIK3CA	5290	broad.mit.edu	37	3	178921552	178921552	+	Missense_Mutation	SNP	A	A	C			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr3:178921552A>C	ENST00000263967.3	+	5	1191	c.1034A>C	c.(1033-1035)aAt>aCt	p.N345T		NM_006218.2	NP_006209.2	P42336	PK3CA_HUMAN	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	345					epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|platelet activation|T cell costimulation|T cell receptor signaling pathway		1-phosphatidylinositol-3-kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity	p.N345I(4)|p.N345S(1)		NS(16)|autonomic_ganglia(4)|biliary_tract(22)|bone(1)|breast(2150)|central_nervous_system(110)|cervix(33)|endometrium(473)|eye(1)|haematopoietic_and_lymphoid_tissue(35)|kidney(14)|large_intestine(1202)|liver(42)|lung(202)|meninges(1)|oesophagus(28)|ovary(235)|pancreas(17)|penis(8)|pituitary(12)|prostate(10)|skin(155)|small_intestine(1)|soft_tissue(18)|stomach(121)|thyroid(80)|upper_aerodigestive_tract(70)|urinary_tract(208)	5269	all_cancers(143;1.19e-17)|Ovarian(172;0.00769)|Breast(254;0.155)		OV - Ovarian serous cystadenocarcinoma(80;9.59e-28)|GBM - Glioblastoma multiforme(14;0.003)|BRCA - Breast invasive adenocarcinoma(182;0.0282)			ACCTACGTGAATGTAAATATT	0.303000		57	Mis		"""colorectal, gastric, gliobastoma, breast"""					HNSCC(19;0.045)|TSP Lung(28;0.18)			19	16					0	0	1	0	0
FBXW7	0	broad.mit.edu	37	4	153249384	153249384	+	Missense_Mutation	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr4:153249384C>T	ENST00000281708.4	-	9	2623	c.1394G>A	c.(1393-1395)cGt>cAt	p.R465H	FBXW7_ENST00000296555.5_Missense_Mutation_p.R347H|FBXW7_ENST00000263981.5_Missense_Mutation_p.R385H|FBXW7_ENST00000603841.1_Missense_Mutation_p.R465H|FBXW7_ENST00000393956.3_Missense_Mutation_p.R289H|FBXW7_ENST00000603548.1_Missense_Mutation_p.R465H	NM_033632.3	NP_361014.1	Q969H0	FBXW7_HUMAN	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	465			R -> C (in a acute lymphoblastic leukemia cell line).|R -> H (in a colorectal cancer sample; somatic mutation).		interspecies interaction between organisms|lipid homeostasis|negative regulation of DNA endoreduplication|negative regulation of hepatocyte proliferation|negative regulation of Notch signaling pathway|negative regulation of triglyceride biosynthetic process|positive regulation of epidermal growth factor receptor activity|positive regulation of ERK1 and ERK2 cascade|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein stabilization|protein ubiquitination|regulation of lipid storage|regulation of protein localization|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|sister chromatid cohesion|vasculature development	nucleolus|nucleoplasm|SCF ubiquitin ligase complex	protein binding	p.R465H(69)|p.R385H(16)|p.R226H(16)|p.R465L(4)|p.R347H(4)|p.R465Y(2)|p.?(1)|p.R385L(1)|p.R226L(1)		NS(1)|biliary_tract(8)|bone(1)|breast(5)|central_nervous_system(6)|cervix(2)|endometrium(36)|haematopoietic_and_lymphoid_tissue(159)|kidney(6)|large_intestine(155)|lung(31)|ovary(10)|pancreas(3)|prostate(2)|skin(6)|stomach(16)|upper_aerodigestive_tract(9)|urinary_tract(6)	462	all_hematologic(180;0.093)	Acute lymphoblastic leukemia(8;0.000629)|all_hematologic(8;0.067)				ATGCATACAACGCACAGTGGA	0.408000			"""Mis, N, D, F"""		"""colorectal, endometrial, T-ALL"""								39	58					0	0	1	0	0
BMF	90427	broad.mit.edu	37	15	40398008	40398008	+	Nonsense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr15:40398008G>A	ENST00000354670.4	-	3	514	c.280C>T	c.(280-282)Cga>Tga	p.R94*	BMF_ENST00000431415.3_Nonsense_Mutation_p.R94*|BMF_ENST00000220446.4_Nonsense_Mutation_p.R94*|BMF_ENST00000558774.1_Nonsense_Mutation_p.R94*|BMF_ENST00000561360.1_Nonsense_Mutation_p.R94*|BMF_ENST00000561282.1_Nonsense_Mutation_p.R94*|BMF_ENST00000559701.1_Nonsense_Mutation_p.R94*|BMF_ENST00000397573.1_Nonsense_Mutation_p.R94*	NM_001003940.1	NP_001003940.1	Q96LC9	BMF_HUMAN	Bcl2 modifying factor	94					activation of pro-apoptotic gene products|induction of apoptosis by intracellular signals|positive regulation of protein homooligomerization|positive regulation of release of cytochrome c from mitochondria	cytosol|mitochondrial outer membrane|myosin complex|plasma membrane	protein binding			endometrium(2)|large_intestine(2)|lung(1)|ovary(1)	6		all_cancers(109;4.18e-18)|all_epithelial(112;6.15e-15)|Lung NSC(122;5.63e-11)|all_lung(180;1.4e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.117)		GBM - Glioblastoma multiforme(113;1.29e-06)|BRCA - Breast invasive adenocarcinoma(123;0.0516)		TAAAAGAGTCGCTGGGGTTCC	0.577000													50	71					0	0	1	0	0
TAF5	6877	broad.mit.edu	37	10	105139460	105139460	+	Missense_Mutation	SNP	G	G	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr10:105139460G>T	ENST00000369839.3	+	4	1232	c.1209G>T	c.(1207-1209)aaG>aaT	p.K403N	TAF5_ENST00000351396.4_Missense_Mutation_p.K403N	NM_006951.3	NP_008882.2	Q15542	TAF5_HUMAN	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	403	Poly-Lys.				histone acetylation|interspecies interaction between organisms|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|viral reproduction	actin cytoskeleton|transcription factor TFIID complex|transcription factor TFTC complex	protein dimerization activity|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding			breast(1)|central_nervous_system(1)|kidney(2)|large_intestine(5)|lung(4)|ovary(2)	15		Colorectal(252;0.0747)|Breast(234;0.128)		Epithelial(162;1.83e-09)|all cancers(201;1.4e-08)|BRCA - Breast invasive adenocarcinoma(275;0.198)		CTAAAAAGAAGAAGCCTAAAA	0.373000													14	20					3.27435e-08	3.94411e-08	1	1	0
LL22NC03-80A10.6	0	broad.mit.edu	37	22	22664606	22664606	+	RNA	SNP	A	A	G			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr22:22664606A>G	ENST00000426066.1	+	0	787					NR_027293.1																						GTCTTCATGCAAACTTGGTAT	0.398000													3	6					0	0	1	0	0
C1QB	713	broad.mit.edu	37	1	22986093	22986093	+	Silent	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:22986093C>T	ENST00000509305.1	+	2	484	c.138C>T	c.(136-138)ggC>ggT	p.G46G	C1QB_ENST00000314933.6_Silent_p.G48G			P02746	C1QB_HUMAN	complement component 1, q subcomponent, B chain	48	Collagen-like 1.				complement activation, classical pathway|innate immune response	collagen|complement component C1 complex				breast(1)|endometrium(2)|large_intestine(1)|lung(9)|prostate(1)	14		Colorectal(325;3.46e-05)|Lung NSC(340;6.55e-05)|all_lung(284;9.87e-05)|Renal(390;0.000219)|Breast(348;0.00262)|Ovarian(437;0.00308)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0227)|OV - Ovarian serous cystadenocarcinoma(117;7.06e-27)|Colorectal(126;1.58e-07)|GBM - Glioblastoma multiforme(114;6.72e-06)|COAD - Colon adenocarcinoma(152;1.13e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000551)|KIRC - Kidney renal clear cell carcinoma(1967;0.0027)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.198)	Abciximab(DB00054)|Adalimumab(DB00051)|Alefacept(DB00092)|Alemtuzumab(DB00087)|Basiliximab(DB00074)|Bevacizumab(DB00112)|Cetuximab(DB00002)|Daclizumab(DB00111)|Efalizumab(DB00095)|Etanercept(DB00005)|Gemtuzumab ozogamicin(DB00056)|Ibritumomab(DB00078)|Immune globulin(DB00028)|Muromonab(DB00075)|Natalizumab(DB00108)|Palivizumab(DB00110)|Rituximab(DB00073)|Tositumomab(DB00081)|Trastuzumab(DB00072)	GGACACCTGGCCCCGATGGCC	0.602000													9	14					0	0	1	0	0
ZIC3	7547	broad.mit.edu	37	X	136649210	136649210	+	Missense_Mutation	SNP	C	C	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chrX:136649210C>A	ENST00000287538.5	+	1	910	c.360C>A	c.(358-360)ttC>ttA	p.F120L	ZIC3_ENST00000370606.3_Missense_Mutation_p.F120L	NM_003413.3	NP_003404.1	O60481	ZIC3_HUMAN	Zic family member 3	120					cell differentiation|positive regulation of transcription from RNA polymerase II promoter	cytoplasm|nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(6)|large_intestine(3)|liver(1)|lung(18)|ovary(3)|soft_tissue(2)|urinary_tract(1)	37	Acute lymphoblastic leukemia(192;0.000127)					AGTTTCTGTTCCGCCAGCGCA	0.677000													4	2					0.00909568	0.00964142	1	1	0
FAM230B	0	broad.mit.edu	37	22	21538171	21538171	+	RNA	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr22:21538171G>A	ENST00000451257.1	+	0	1157																											CGAGGACGCCGCCCAGGGCAT	0.726000													2	0					0	0	1	0	0
MT-CO1	4512	broad.mit.edu	37	MT	6121	6121	+	Missense_Mutation	SNP	T	T	C			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chrM:6121T>C	ENST00000361624.2	+	1	218	c.218T>C	c.(217-219)aTc>aCc	p.73_73insT						mitochondrially encoded cytochrome c oxidase I											breast(4)|endometrium(25)|kidney(19)|lung(3)|prostate(3)	54						AGTAATACCCATCATAATCGG	0.473000													63	20					0	0	1	0	0
ATP4A	495	broad.mit.edu	37	19	36046394	36046394	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr19:36046394G>A	ENST00000262623.3	-	14	2133	c.2105C>T	c.(2104-2106)gCg>gTg	p.A702V		NM_000704.2	NP_000695.2	P20648	ATP4A_HUMAN	ATPase, H+/K+ exchanging, alpha polypeptide	702					ATP biosynthetic process|ATP hydrolysis coupled proton transport	integral to plasma membrane	ATP binding|hydrogen:potassium-exchanging ATPase activity|magnesium ion binding			breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|lung(26)|ovary(2)|prostate(2)|upper_aerodigestive_tract(1)	53	all_lung(56;1.05e-07)|Lung NSC(56;1.63e-07)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0724)		Esomeprazole(DB00736)|Lansoprazole(DB00448)|Omeprazole(DB00338)|Pantoprazole(DB00213)|Rabeprazole(DB01129)|Trifluoperazine(DB00831)	GCTGGTGCGCGCAAACACCAT	0.662000													5	163					0	0	1	0	0
SERPINB2	5055	broad.mit.edu	37	18	61570285	61570285	+	Missense_Mutation	SNP	G	G	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr18:61570285G>A	ENST00000457692.1	+	9	1327	c.994G>A	c.(994-996)Gcc>Acc	p.A332T	SERPINB2_ENST00000299502.4_Missense_Mutation_p.A332T	NM_001143818.1	NP_001137290.1	P05120	PAI2_HUMAN	serpin peptidase inhibitor, clade B (ovalbumin), member 2	332					anti-apoptosis|blood coagulation|fibrinolysis|regulation of proteolysis	extracellular space|Golgi apparatus|plasma membrane	serine-type endopeptidase inhibitor activity			NS(1)|central_nervous_system(2)|endometrium(4)|large_intestine(7)|liver(1)|lung(12)|prostate(2)|skin(2)|stomach(1)	32		Esophageal squamous(42;0.131)			Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)|Urokinase(DB00013)	CATGGAGGACGCCTTCAACAA	0.463000													22	33					0	0	1	0	0
POTED	317754	broad.mit.edu	37	21	14982927	14982927	+	Silent	SNP	C	C	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr21:14982927C>T	ENST00000299443.5	+	1	430	c.378C>T	c.(376-378)agC>agT	p.S126S		NM_174981.3|NM_207355.2	NP_778146.2|NP_997238.2	Q86YR6	POTED_HUMAN	POTE ankyrin domain family, member D	126						plasma membrane				central_nervous_system(1)|large_intestine(10)|liver(2)|lung(8)|ovary(4)|pancreas(1)|prostate(1)|skin(5)|stomach(1)	33						ACGACCACAGCGCCTTCATGG	0.597000													50	89					0	0	1	0	0
ARHGEF10L	55160	broad.mit.edu	37	1	17944985	17944987	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:17944985_17944987delCCT	ENST00000375408.3	+	1	175_177	c.137_139delCCT	c.(136-141)ccc>c	p.PS46del	ARHGEF10L_ENST00000167825.4_In_Frame_Del_p.PS46del|ARHGEF10L_ENST00000361221.3_Intron|ARHGEF10L_ENST00000469726.1_Intron|ARHGEF10L_ENST00000452522.1_Intron|ARHGEF10L_ENST00000434513.1_Intron|ARHGEF10L_ENST00000375415.1_Intron|ARHGEF10L_ENST00000375420.3_Intron			Q9HCE6	ARGAL_HUMAN	Rho guanine nucleotide exchange factor (GEF) 10-like	0					regulation of Rho protein signal transduction	cytoplasm	Rho guanyl-nucleotide exchange factor activity			NS(1)|breast(1)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|liver(2)|lung(16)|ovary(4)|pancreas(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	43		Colorectal(325;3.46e-05)|Breast(348;0.000162)|all_lung(284;0.000337)|Lung NSC(340;0.000419)|Renal(390;0.000518)|Ovarian(437;0.00409)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00598)|COAD - Colon adenocarcinoma(227;1.62e-05)|BRCA - Breast invasive adenocarcinoma(304;1.68e-05)|Kidney(64;0.000269)|KIRC - Kidney renal clear cell carcinoma(64;0.00361)|STAD - Stomach adenocarcinoma(196;0.00656)|READ - Rectum adenocarcinoma(331;0.0718)|Lung(427;0.204)		ATCCGCTGTCcctcctcctcctc	0.680													3	4	---	---	---	---					
RP11-435B5.4	0	broad.mit.edu	37	1	143412865	143412865	+	RNA	DEL	A	A	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:143412865delA	ENST00000423249.1	-	0	59																											aggctgacagaaggatggaca	0.413													2	4	---	---	---	---					
SETDB1	9869	broad.mit.edu	37	1	150933180	150933181	+	Frame_Shift_Del	DEL	GT	GT	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:150933180_150933181delGT	ENST00000271640.5	+	16	2832_2833	c.2642_2643delGT	c.(2641-2643)afs	p.S881fs	SETDB1_ENST00000368969.4_Frame_Shift_Del_p.S881fs|SETDB1_ENST00000459773.1_3'UTR	NM_001145415.1|NM_012432.3	NP_001138887.1|NP_036564.3	Q15047	SETB1_HUMAN	SET domain, bifurcated 1	881	SET.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|Golgi apparatus|nucleus|plasma membrane	DNA binding|histone-lysine N-methyltransferase activity|protein binding|zinc ion binding			NS(1)|large_intestine(5)|ovary(3)|skin(2)|upper_aerodigestive_tract(1)	12	all_lung(15;9e-35)|Lung NSC(24;3.45e-31)|Lung SC(34;0.00471)|Ovarian(49;0.0167)|all_hematologic(923;0.0597)|Hepatocellular(266;0.108)|Melanoma(130;0.185)		UCEC - Uterine corpus endometrioid carcinoma (35;0.0486)|BRCA - Breast invasive adenocarcinoma(12;0.0152)|LUSC - Lung squamous cell carcinoma(543;0.211)			TCTGACAGCAGTGGTGTAGACT	0.475													28	47	---	---	---	---					
SPRTN	83932	broad.mit.edu	37	1	231487057	231487057	+	Frame_Shift_Del	DEL	A	A	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr1:231487057delA	ENST00000391858.4	+	4	1738	c.458delA	c.(457-459)ctfs	p.H153fs	SPRTN_ENST00000295050.7_Frame_Shift_Del_p.H153fs|SPRTN_ENST00000469904.1_3'UTR|SPRTN_ENST00000008440.9_Frame_Shift_Del_p.H110fs					SprT-like N-terminal domain																		CAGGTATACCATACTTTTCAC	0.413													19	64	---	---	---	---					
AC010745.2	0	broad.mit.edu	37	2	16407935	16407935	+	RNA	DEL	T	T	-	rs78167150		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:16407935delT	ENST00000420404.1	+	0	165																											CAGTCCCCCCTCTTCCCCAGT	0.557													2	4	---	---	---	---					
AC007392.4	0	broad.mit.edu	37	2	66926854	66926855	+	RNA	INS	-	-	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:66926854_66926855insA	ENST00000433432.1	-	0	594																											CACACTCAGGGAAAAAAAAAAA	0.337													2	4	---	---	---	---					
AC010987.5	0	broad.mit.edu	37	2	67909275	67909276	+	RNA	INS	-	-	T	rs72538484	by1000genomes	TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:67909275_67909276insT	ENST00000419809.1	-	0	126																											TAAATAGTTGATTTTTTTTTGG	0.386													5	2	---	---	---	---					
AC010987.6	0	broad.mit.edu	37	2	68023828	68023829	+	RNA	DEL	AC	AC	-	rs150402203		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:68023828_68023829delAC	ENST00000457448.1	-	0	180																											Tcacgcacatacacacacacac	0.436													3	5	---	---	---	---					
AC027612.3	0	broad.mit.edu	37	2	91875150	91875151	+	RNA	INS	-	-	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:91875150_91875151insA	ENST00000436174.1	-	0	1044																											AACCCAGACTGAAAAAAAAATG	0.455													2	4	---	---	---	---					
AC018730.3	0	broad.mit.edu	37	2	105485400	105485400	+	RNA	DEL	G	G	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:105485400delG	ENST00000433433.1	-	0	207				RP11-13J10.1_ENST00000598623.1_RNA																							GGGTGAGGGTGGGGCAGGGAG	0.418													2	4	---	---	---	---					
AC097532.2	0	broad.mit.edu	37	2	133046597	133046597	+	RNA	DEL	A	A	-	rs111715068		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr2:133046597delA	ENST00000440802.1	-	0	101																											TCTGAGCTCGAGGCCCCCCAA	0.597													4	4	---	---	---	---					
RP11-141E13.1	0	broad.mit.edu	37	4	17032166	17032166	+	RNA	DEL	T	T	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr4:17032166delT	ENST00000511735.1	-	0	154																											TGGAAACTAGTTTTAATGCAC	0.463													2	4	---	---	---	---					
RP11-231C18.1	0	broad.mit.edu	37	4	55201975	55201975	+	RNA	DEL	A	A	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr4:55201975delA	ENST00000511634.1	+	0	43																											CAGGAACTCTAAAAGGGGGTG	0.458													2	4	---	---	---	---					
PIK3R1	5295	broad.mit.edu	37	5	67576381	67576382	+	Frame_Shift_Ins	INS	-	-	C			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr5:67576381_67576382insC	ENST00000521381.1	+	6	1276_1277	c.660_661insC	c.(658-663)atagctfs	p.A221fs	PIK3R1_ENST00000396611.1_Frame_Shift_Ins_p.A221fs|PIK3R1_ENST00000521657.1_Frame_Shift_Ins_p.A221fs|PIK3R1_ENST00000274335.5_Frame_Shift_Ins_p.A221fs	NM_181523.2	NP_852664.1	P27986	P85A_HUMAN	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	221	Rho-GAP.				epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|growth hormone receptor signaling pathway|insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|interspecies interaction between organisms|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol 3-kinase cascade|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|platelet activation|positive regulation of establishment of protein localization in plasma membrane|positive regulation of glucose import|T cell costimulation|T cell receptor signaling pathway	1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex	1-phosphatidylinositol binding|ErbB-3 class receptor binding|insulin binding|insulin receptor binding|insulin receptor substrate binding|insulin-like growth factor receptor binding|phosphatidylinositol 3-kinase regulator activity|protein phosphatase binding	p.0?(1)|p.?(1)		breast(12)|central_nervous_system(31)|cervix(1)|endometrium(68)|haematopoietic_and_lymphoid_tissue(5)|kidney(1)|large_intestine(32)|lung(10)|ovary(9)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	178		Lung NSC(167;1.99e-05)|Prostate(74;0.00308)|Ovarian(174;0.00473)|Colorectal(97;0.0176)		OV - Ovarian serous cystadenocarcinoma(47;3.76e-51)|Lung(70;0.0211)	Isoproterenol(DB01064)	AAGAATATATTCAGCTATTGAA	0.351			"""Mis, F, O"""		"""gliobastoma, ovarian, colorectal"""					TCGA GBM(4;<1E-08)			104	90	---	---	---	---					
RP5-1120P11.1	0	broad.mit.edu	37	6	43976440	43976440	+	RNA	DEL	G	G	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr6:43976440delG	ENST00000422059.1	-	0	156																											CTCAGGCCCTGTGCACCTCTT	0.577													2	4	---	---	---	---					
INHBA-AS1	0	broad.mit.edu	37	7	41812982	41812983	+	RNA	INS	-	-	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr7:41812982_41812983insT	ENST00000415848.2	+	0	457					NR_027118.1																						gccTACTGTCATTTTTTTATTC	0.460													2	4	---	---	---	---					
PMS2P4	0	broad.mit.edu	37	7	66762433	66762433	+	RNA	DEL	A	A	-	rs68053451		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr7:66762433delA	ENST00000414507.1	-	0	184																											tctcaaaaagaaaaaaaaaaa	0.408													3	4	---	---	---	---					
RP4-798C17.6	0	broad.mit.edu	37	7	144027120	144027121	+	RNA	INS	-	-	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr7:144027120_144027121insA	ENST00000463561.1	-	0	411				RP4-798C17.6_ENST00000496968.1_RNA|RP4-798C17.6_ENST00000478806.1_RNA|RP4-798C17.6_ENST00000461843.1_RNA|RP4-798C17.6_ENST00000489488.1_RNA|RP4-798C17.6_ENST00000478925.1_RNA|RP4-798C17.6_ENST00000493539.1_RNA|RP4-798C17.6_ENST00000488041.1_RNA|RP4-798C17.6_ENST00000476560.1_RNA|RP4-798C17.6_ENST00000475089.1_RNA|RP4-798C17.6_ENST00000467944.1_RNA|RP4-798C17.6_ENST00000486094.1_RNA|RP4-798C17.6_ENST00000487102.1_RNA																							ccctgtctcagaaaaaaaaaaa	0.441													2	4	---	---	---	---					
ERICH1-AS1	0	broad.mit.edu	37	8	1047564	1047565	+	RNA	INS	-	-	C			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr8:1047564_1047565insC	ENST00000522092.1	+	0	332				ERICH1-AS1_ENST00000578889.1_RNA	NR_073397.1|NR_073466.1																						GGAGCTGGGAGCCCGGGGCAGG	0.668													2	4	---	---	---	---					
RP11-124B13.1	0	broad.mit.edu	37	8	5921321	5921321	+	RNA	DEL	A	A	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr8:5921321delA	ENST00000519555.1	-	0	250																											gtggcagggtaggaggctaac	0.443													2	4	---	---	---	---					
MROH5	389690	broad.mit.edu	37	8	142485425	142485425	+	RNA	DEL	C	C	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr8:142485425delC	ENST00000430863.1	-	0	1749					NM_207414.2	NP_997297.2			maestro heat-like repeat family member 5																		GGTGACTGTGCCCAGGAGCCA	0.617													2	4	---	---	---	---					
RP11-561O23.5	0	broad.mit.edu	37	9	70938998	70938998	+	RNA	DEL	A	A	-	rs56822289		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr9:70938998delA	ENST00000429953.2	+	0	1335																											GTGCCTCCCCACCTGCTATGG	0.706													2	4	---	---	---	---					
TTF1	7270	broad.mit.edu	37	9	135251330	135251330	+	Frame_Shift_Del	DEL	A	A	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr9:135251330delA	ENST00000334270.2	-	11	2729	c.2690delT	c.(2689-2691)tgfs	p.L897fs	TTF1_ENST00000461970.1_5'UTR	NM_001205296.1|NM_007344.3	NP_001192225.1|NP_031370.2	Q15361	TTF1_HUMAN	transcription termination factor, RNA polymerase I	897					negative regulation of DNA replication|regulation of transcription, DNA-dependent|termination of RNA polymerase I transcription	nucleolus|nucleoplasm	DNA binding			endometrium(3)|kidney(1)|large_intestine(5)|lung(13)|ovary(2)|pancreas(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	30		Myeloproliferative disorder(178;0.204)		OV - Ovarian serous cystadenocarcinoma(145;4.25e-06)|Epithelial(140;9.09e-05)		ttggcctcccaaagtactgga	0.483													4	9	---	---	---	---					
CCNYL2	414194	broad.mit.edu	37	10	42950275	42950275	+	RNA	DEL	C	C	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr10:42950275delC	ENST00000483242.3	-	0	623					NR_103829.1				cyclin Y-like 2											breast(2)|endometrium(1)|lung(3)|ovary(1)	7						TGCCACCCCTCCCCCACAGCT	0.647													2	4	---	---	---	---					
RP11-25I9.2	0	broad.mit.edu	37	11	108901835	108901836	+	RNA	INS	-	-	AG			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr11:108901835_108901836insAG	ENST00000526041.1	-	0	225																											GGCTGGAGTGCTGGCTTCCTGC	0.545													3	3	---	---	---	---					
SRP14-AS1	0	broad.mit.edu	37	15	40342650	40342651	+	RNA	INS	-	-	TG	rs10592603	by1000genomes	TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr15:40342650_40342651insTG	ENST00000504245.1	+	0	247					NR_040060.1																						GGTCTAGCCCTtgtgtgtgtgt	0.540													2	4	---	---	---	---					
Z84812.4	0	broad.mit.edu	37	16	70942	70942	+	RNA	DEL	G	G	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr16:70942delG	ENST00000568710.1	-	0	434																											ccgtgggtgtgggaccctccg	0.572													2	4	---	---	---	---					
RP11-876N24.2	0	broad.mit.edu	37	16	10968825	10968826	+	RNA	INS	-	-	T			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr16:10968825_10968826insT	ENST00000572017.1	-	0	438																											GAAtttctttctttttttttct	0.490													2	4	---	---	---	---					
RP11-67H24.2	0	broad.mit.edu	37	16	32833858	32833859	+	RNA	INS	-	-	A			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr16:32833858_32833859insA	ENST00000569859.1	+	0	373																											tccttctttttctttctttgtt	0.342													2	4	---	---	---	---					
RP11-23E10.3	0	broad.mit.edu	37	16	33337174	33337174	+	RNA	DEL	G	G	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr16:33337174delG	ENST00000567464.1	-	0	212																											ctggacaacagggtgaaactc	0.532													2	4	---	---	---	---					
RP11-467L24.1	0	broad.mit.edu	37	16	64566952	64566952	+	RNA	DEL	C	C	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr16:64566952delC	ENST00000564046.1	+	0	354																											GCCGGCTCCTCAATGCCCTCA	0.488													2	4	---	---	---	---					
ZNF830	91603	broad.mit.edu	37	17	33289163	33289164	+	Frame_Shift_Del	DEL	CA	CA	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr17:33289163_33289164delCA	ENST00000361952.3	+	1	615_616	c.578_579delCA	c.(577-579)tfs	p.S193fs		NM_052857.3	NP_443089.3	Q96NB3	ZN830_HUMAN	zinc finger protein 830	193					cell division|mitosis	cytoplasm|nucleus	metal ion binding			breast(1)|cervix(1)|endometrium(2)|large_intestine(1)|liver(2)|lung(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	13		Ovarian(249;0.17)				AAGGAGCACTCAGTTTCCTCTT	0.525													22	23	---	---	---	---					
RP11-101O21.1	0	broad.mit.edu	37	17	72109854	72109854	+	RNA	DEL	G	G	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr17:72109854delG	ENST00000584003.1	-	0	258																											cgcagcctgagggagccggct	0.716													2	4	---	---	---	---					
CTC-525D6.1	0	broad.mit.edu	37	19	29783808	29783808	+	RNA	DEL	A	A	-	rs11309855		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr19:29783808delA	ENST00000582581.1	-	0	2030					NR_040029.1																						gaatgatgagaaaaaaatagc	0.498													12	1	---	---	---	---					
CTD-2050I18.1	0	broad.mit.edu	37	19	32043171	32043174	+	RNA	DEL	TGAC	TGAC	-	rs146439928		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr19:32043171_32043174delTGAC	ENST00000593063.1	+	0	345																											gcttcaaatatgactttaagccta	0.431													6	1	---	---	---	---					
SNAP25-AS1	0	broad.mit.edu	37	20	10348858	10348859	+	RNA	INS	-	-	T	rs140527189	by1000genomes	TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr20:10348858_10348859insT	ENST00000421143.2	-	0	5				SNAP25-AS1_ENST00000453544.1_RNA																							TAGGttttttgtttttttttta	0.450													3	5	---	---	---	---					
JAG1	182	broad.mit.edu	37	20	10653632	10653635	+	Frame_Shift_Del	DEL	AACT	AACT	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr20:10653632_10653635delAACT	ENST00000254958.5	-	2	616_619	c.101_104delAGTT	c.(100-105)ccfs	p.QF34fs	RP11-103J8.1_ENST00000605292.1_RNA	NM_000214.2	NP_000205.1	P78504	JAG1_HUMAN	jagged 1	34					angiogenesis|cell communication|cell fate determination|endothelial cell differentiation|hemopoiesis|keratinocyte differentiation|myoblast differentiation|Notch receptor processing|Notch signaling pathway|regulation of cell migration|regulation of cell proliferation	extracellular region|integral to plasma membrane	calcium ion binding|growth factor activity|Notch binding|structural molecule activity			biliary_tract(1)|breast(2)|central_nervous_system(3)|cervix(1)|endometrium(6)|kidney(3)|large_intestine(10)|lung(14)|ovary(2)|pancreas(1)|urinary_tract(1)	44						CTCCAACTCGAACTGACCCGAGGC	0.642									Alagille Syndrome				22	62	---	---	---	---					
RP5-1100I6.2	0	broad.mit.edu	37	20	24189152	24189153	+	RNA	DEL	GT	GT	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr20:24189152_24189153delGT	ENST00000457274.1	+	0	68					NR_040102.1																						gtgtgcgtgcgtgtgtgtttgt	0.515													3	6	---	---	---	---					
RP4-610C12.1	0	broad.mit.edu	37	20	29595625	29595625	+	RNA	DEL	T	T	-	rs111897002		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr20:29595625delT	ENST00000432067.1	-	0	74																											TGTAAAAAAATCACAGGATCC	0.408													3	5	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11039939	11039941	+	RNA	DEL	GTT	GTT	-	rs146620410		TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr21:11039939_11039941delGTT	ENST00000470054.1	-	0	774									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		GGATATAATCGTTGTTCTTCATC	0.320													4	4	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11056529	11056530	+	RNA	DEL	GA	GA	-			TCGA-N5-A4RS-01A-11D-A28R-08	TCGA-N5-A4RS-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5af5265b-b489-4307-b4b7-9ea5d8f1b461	a5091274-8175-4e71-831a-a07f6aef2908	g.chr21:11056529_11056530delGA	ENST00000470054.1	-	0	487									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		gtatttttatgagtctccataa	0.272													2	4	---	---	---	---