Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	ref_context	gc_content	COSMIC_n_overlapping_mutations	ESP_AvgAAsampleReadDepth	ESP_AvgEAsampleReadDepth	ESP_AvgSampleReadDepth	ESP_Chromosome	ESP_Position	ESP_TotalAAsamplesCovered	ESP_TotalEAsamplesCovered	ESP_TotalSamplesCovered	Ensembl_so_accession	Ensembl_so_term	HGNC_AccessionNumbers	HGNC_CCDSIDs	HGNC_Chromosome	HGNC_DateModified	HGNC_DateNameChanged	HGNC_DateSymbolChanged	HGNC_EnsemblGeneID	HGNC_EnsemblIDsuppliedbyEnsembl	HGNC_Genefamilydescription	HGNC_HGNCID	HGNC_LocusGroup	HGNC_LocusType	HGNC_NameSynonyms	HGNC_OMIMIDsuppliedbyNCBI	HGNC_PreviousNames	HGNC_PreviousSymbols	HGNC_PubmedIDs	HGNC_RecordType	HGNC_RefSeqsuppliedbyNCBI	HGNC_Status	HGNC_Synonyms	HGNC_UCSCIDsuppliedbyUCSC	HGNC_UniProtIDsuppliedbyUniProt	HGNC_VEGAIDs	HGVS_coding_DNA_change	HGVS_genomic_change	HGVS_protein_change	UniProt_alt_uniprot_accessions	annotation_transcript	build	ccds_id	dbNSFP_1000Gp1_AC	dbNSFP_1000Gp1_AF	dbNSFP_1000Gp1_AFR_AC	dbNSFP_1000Gp1_AFR_AF	dbNSFP_1000Gp1_AMR_AC	dbNSFP_1000Gp1_AMR_AF	dbNSFP_1000Gp1_ASN_AC	dbNSFP_1000Gp1_ASN_AF	dbNSFP_1000Gp1_EUR_AC	dbNSFP_1000Gp1_EUR_AF	dbNSFP_Ancestral_allele	dbNSFP_CADD_phred	dbNSFP_CADD_raw	dbNSFP_CADD_raw_rankscore	dbNSFP_ESP6500_AA_AF	dbNSFP_ESP6500_EA_AF	dbNSFP_Ensembl_geneid	dbNSFP_Ensembl_transcriptid	dbNSFP_FATHMM_pred	dbNSFP_FATHMM_rankscore	dbNSFP_FATHMM_score	dbNSFP_GERP_NR	dbNSFP_GERP_RS	dbNSFP_GERP_RS_rankscore	dbNSFP_Interpro_domain	dbNSFP_LRT_Omega	dbNSFP_LRT_converted_rankscore	dbNSFP_LRT_pred	dbNSFP_LRT_score	dbNSFP_LR_pred	dbNSFP_LR_rankscore	dbNSFP_LR_score	dbNSFP_MutationAssessor_pred	dbNSFP_MutationAssessor_rankscore	dbNSFP_MutationAssessor_score	dbNSFP_MutationTaster_converted_rankscore	dbNSFP_MutationTaster_pred	dbNSFP_MutationTaster_score	dbNSFP_Polyphen2_HDIV_pred	dbNSFP_Polyphen2_HDIV_rankscore	dbNSFP_Polyphen2_HDIV_score	dbNSFP_Polyphen2_HVAR_pred	dbNSFP_Polyphen2_HVAR_rankscore	dbNSFP_Polyphen2_HVAR_score	dbNSFP_RadialSVM_pred	dbNSFP_RadialSVM_rankscore	dbNSFP_RadialSVM_score	dbNSFP_Reliability_index	dbNSFP_SIFT_converted_rankscore	dbNSFP_SIFT_pred	dbNSFP_SIFT_score	dbNSFP_SLR_test_statistic	dbNSFP_SiPhy_29way_logOdds	dbNSFP_SiPhy_29way_logOdds_rankscore	dbNSFP_SiPhy_29way_pi	dbNSFP_UniSNP_ids	dbNSFP_Uniprot_aapos	dbNSFP_Uniprot_acc	dbNSFP_Uniprot_id	dbNSFP_aaalt	dbNSFP_aapos	dbNSFP_aapos_FATHMM	dbNSFP_aapos_SIFT	dbNSFP_aaref	dbNSFP_cds_strand	dbNSFP_codonpos	dbNSFP_folddegenerate	dbNSFP_genename	dbNSFP_hg18_pos1coor	dbNSFP_phastCons100way_vertebrate	dbNSFP_phastCons100way_vertebrate_rankscore	dbNSFP_phastCons46way_placental	dbNSFP_phastCons46way_placental_rankscore	dbNSFP_phastCons46way_primate	dbNSFP_phastCons46way_primate_rankscore	dbNSFP_phyloP100way_vertebrate	dbNSFP_phyloP100way_vertebrate_rankscore	dbNSFP_phyloP46way_placental	dbNSFP_phyloP46way_placental_rankscore	dbNSFP_phyloP46way_primate	dbNSFP_phyloP46way_primate_rankscore	dbNSFP_refcodon	gencode_transcript_name	gencode_transcript_status	gencode_transcript_tags	gencode_transcript_type	gene_type	havana_transcript	init_n_lod	init_t_lod	isArtifactMode	n_alt_count	n_ref_count	oxoGCut	pox	pox_cutoff	qox	refseq_mrna_id	t_alt_count	t_lod_fstar	t_ref_count	tumor_f
LCE4A	199834	broad.mit.edu	hg19	1	152681848	152681848	+	Silent	SNP	C	C	T			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr1:152681848C>T	ENST00000368777.1	+	2	553	c.297C>T	c.(295-297)tgC>tgT	p.C99C	LCE4A_ENST00000335535.3_Silent_p.C99C			Q5TA78	LCE4A_HUMAN	late cornified envelope 4A	99	Cys-rich.	keratinization			endometrium(1)|kidney(1)|large_intestine(2)|lung(5)|skin(1)	10	Hepatocellular(266;0.0877)|all_hematologic(923;0.127)|Melanoma(130;0.242)		LUSC - Lung squamous cell carcinoma(543;0.116)		GGGGCTGTTGCTGACCTGGAC	0.567	0	22.0	25.0	24.0	1	152681848	2201	4298	6499	SO:0001819	synonymous_variant	BI670517	CCDS1022.1	1q22	2008-02-05	2004-10-11	2004-10-15	ENSG00000187170	ENSG00000187170	"""Late cornified envelopes"""	16613	protein-coding gene	gene with protein product		612618	"""small proline rich-like (epidermal differentiation complex) 4A"""	SPRL4A	11698679	Standard	NM_178356	Approved	LEP8	uc001fak.2	Q5TA78	OTTHUMG00000014394	ENST00000368777.1:c.297C>T	1.37:g.152681848C>T		Q14D97	ENST00000368777.1	37	CCDS1022.1																																																																																			LCE4A-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000040048.1		69.783520	0	-1	37	0	0	1	0	NM_178356	21	70.323531	12	0.636364
AKAP13	11214	hgsc.bcm.edu	hg19	15	86125034	86125034	+	Silent	SNP	A	A	G			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08	A	A	.	.	.	.	Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina HiSeq	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b																										CTAAGGGGGCAGACTTGATAG	0.592	0	43.0	42.0	42.0	15	86125034	2202	4299	6501	SO:0001819	synonymous_variant	M90360	CCDS32319.1, CCDS32320.1, CCDS73778.1	15q24-q25	2013-01-10	2002-06-13			ENSG00000170776	"""A-kinase anchor proteins"", ""Rho guanine nucleotide exchange factors"", ""Pleckstrin homology (PH) domain containing"""	371	protein-coding gene	gene with protein product		604686	"""lymphoid blast crisis oncogene"""	LBC	9627117, 1860836	Standard	NM_007200	Approved	Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13	uc002blu.2	Q12802		ENST00000361243.2:c.3735A>G	15.37:g.86125034A>G		Q14572|Q59FP6|Q86W90|Q8WXQ6|Q96JP6|Q96P79|Q9Y5T0|Q9Y5T6	ENST00000361243.2	37	CCDS32320.1																																																																																			AKAP13-001	KNOWN	basic|appris_candidate_longest|CCDS	protein_coding	protein_coding	OTTHUMT00000417319.1				14	45					NM_007200	9		26	
WTIP	126374	broad.mit.edu	hg19	19	34991049	34991049	+	Silent	SNP	C	C	T			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr19:34991049C>T	ENST00000590071.2	+	8	1505	c.1168C>T	c.(1168-1170)Ctg>Ttg	p.L390L	WTIP_ENST00000270288.6_Silent_p.L614L	NM_001080436.1	NP_001073905.1			Wilms tumor 1 interacting protein						NS(1)|large_intestine(2)|lung(1)	4	all_lung(56;5.94e-07)|Lung NSC(56;9.35e-07)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.211)		CGGGCTGCAGCTGAGCGGGGA	0.682	0	30.0	37.0	35.0	19	34991049	2144	4246	6390	SO:0001819	synonymous_variant	AK130059	CCDS59375.1	19q13.11	2012-03-16			ENSG00000142279	ENSG00000142279		20964	protein-coding gene	gene with protein product	"""WT1-interacting protein"""	614790			14736876	Standard	NM_001080436	Approved		uc002nvm.3	A6NIX2		ENST00000590071.2:c.1168C>T	19.37:g.34991049C>T			ENST00000590071.2	37	CCDS59375.1																																																																																			WTIP-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000459381.3		13.567065	0	-5	33	0	0	1	0	XM_059037	5	14.366950	13	0.277778
SLC6A4	6532	broad.mit.edu	hg19	17	28525481	28525481	+	Missense_Mutation	SNP	G	G	A			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr17:28525481G>A	ENST00000401766.2	-	14	2398	c.1886C>T	c.(1885-1887)gCt>gTt	p.A629V	SLC6A4_ENST00000261707.3_Missense_Mutation_p.A629V			P31645	SC6A4_HUMAN	solute carrier family 6 (neurotransmitter transporter), member 4	629	Required for serotonin uptake activity.	response to toxin|serotonin uptake|thalamus development	cytosol|endomembrane system|endosome membrane|membrane raft	actin filament binding|Rab GTPase binding|serotonin transmembrane transporter activity|serotonin:sodium symporter activity	breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(8)|ovary(1)|prostate(1)|skin(4)	25					GTGTTACACAGCATTCAAGCG	0.443	0	136.0	124.0	128.0	17	28525481	2203	4300	6503	SO:0001583	missense	L05568	CCDS11256.1	17q11.2	2014-01-30	2013-07-19		ENSG00000108576	ENSG00000108576	"""Solute carriers"""	11050	protein-coding gene	gene with protein product	"""serotonin transporter 1"""	182138	"""solute carrier family 6 (neurotransmitter transporter, serotonin), member 4"", ""5-hydroxytryptamine (serotonin) transporter"", ""obsessive-compulsive disorder 1"""	HTT, OCD1	7681602, 19806148	Standard	NM_001045	Approved	5-HTT, SERT1	uc002hey.5	P31645	OTTHUMG00000132751	ENST00000401766.2:c.1886C>T	17.37:g.28525481G>A	ENSP00000385822:p.Ala629Val	Q5EE02	ENST00000401766.2	37	CCDS11256.1	.	.	.	.	.	.	.	.	.	.	G	16.88	3.244033	0.58995	.	.	ENSG00000108576	ENST00000394821;ENST00000401766;ENST00000261707	T;T	0.75938	-0.98;-0.98	6.06	4.01	0.46588	.	0.322504	0.34700	N	0.003760	T	0.54615	0.1869	N	0.08118	0	0.35298	D	0.782778	B	0.06786	0.001	B	0.06405	0.002	T	0.58205	-0.7677	10	0.66056	D	0.02	.	11.1053	0.48199	0.1549:0.0:0.8451:0.0	.	629	P31645	SC6A4_HUMAN	V	671;629;629	ENSP00000385822:A629V;ENSP00000261707:A629V	ENSP00000261707:A629V	A	-	2	0	SLC6A4	25549607	0.997000	0.39634	0.970000	0.41538	0.849000	0.48306	2.297000	0.43593	0.820000	0.34516	-0.345000	0.07892	GCT	SLC6A4-002	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000256115.3		-6.307910	0	-9	70	0	0	1	0	NM_001045	3	6.562306	57	0.050000
LRRN3	54674	broad.mit.edu	hg19	7	110763686	110763686	+	Silent	SNP	A	A	G			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr7:110763686A>G	ENST00000451085.1	+	4	1904	c.858A>G	c.(856-858)ttA>ttG	p.L286L	IMMP2L_ENST00000452895.1_Intron|IMMP2L_ENST00000447215.1_Intron|LRRN3_ENST00000308478.5_Silent_p.L286L|IMMP2L_ENST00000415362.1_Intron|IMMP2L_ENST00000331762.3_Intron|IMMP2L_ENST00000489381.1_Intron|IMMP2L_ENST00000450877.1_Intron|LRRN3_ENST00000422987.3_Silent_p.L286L|IMMP2L_ENST00000405709.2_Intron|IMMP2L_ENST00000437687.1_Intron	NM_001099660.1	NP_001093130.1	Q9H3W5	LRRN3_HUMAN	leucine rich repeat neuronal 3	286			integral to membrane		NS(1)|breast(1)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(15)|lung(20)|ovary(2)|pancreas(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	55				UCEC - Uterine corpus endometrioid carcinoma (4;0.245)|LUSC - Lung squamous cell carcinoma(290;0.0715)|Lung(3;0.0864)|STAD - Stomach adenocarcinoma(3;0.125)	TGCTACACTTAAAAGAGTTGG	0.328	0	58.0	62.0	60.0	7	110763686	2203	4300	6503	SO:0001819	synonymous_variant	AB060967	CCDS5754.1	7q31.1	2013-02-11			ENSG00000173114	ENSG00000173114	"""Immunoglobulin superfamily / I-set domain containing"", ""Fibronectin type III domain containing"""	17200	protein-coding gene	gene with protein product	"""fibronectin type III, immunoglobulin and leucine rich repeat domains 5"""				11549284	Standard	NM_001099660	Approved	NLRR3, FLJ11129, FIGLER5	uc003vfs.4	Q9H3W5	OTTHUMG00000155039	ENST00000422987.3:c.858A>G	7.37:g.110763686A>G		O43377|Q6I9V8|Q8IYQ6	ENST00000422987.3	37	CCDS5754.1																																																																																			LRRN3-002	KNOWN	alternative_5_UTR|basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000338171.2		73.747393	0	-3	62	0	0	1	0	NM_018334	22	73.819709	26	0.458333
ZDHHC6	64429	broad.mit.edu	hg19	10	114192275	114192275	+	Missense_Mutation	SNP	C	C	T			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr10:114192275C>T	ENST00000369405.3	-	9	1373	c.950G>A	c.(949-951)cGc>cAc	p.R317H	ZDHHC6_ENST00000482410.1_5'UTR|ZDHHC6_ENST00000369404.3_Missense_Mutation_p.R313H	NM_022494.1	NP_071939.1	Q9H6R6	ZDHC6_HUMAN	zinc finger, DHHC-type containing 6	317			integral to membrane	acyltransferase activity|zinc ion binding	endometrium(4)|kidney(1)|large_intestine(2)|lung(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	14		Colorectal(252;0.198)		Epithelial(162;0.0291)|all cancers(201;0.117)	TACTTTATAGCGAACCTGTCG	0.378	0	83.0	80.0	81.0	10	114192275	2203	4300	6503	SO:0001583	missense	AK025605	CCDS7574.1	10q26.11	2008-05-02			ENSG00000023041	ENSG00000023041	"""Zinc fingers, DHHC-type"""	19160	protein-coding gene	gene with protein product						Standard	NM_022494	Approved	ZNF376, FLJ21952	uc001kzv.3	Q9H6R6	OTTHUMG00000019062	ENST00000369405.3:c.950G>A	10.37:g.114192275C>T	ENSP00000358413:p.Arg317His	D3DRB6|Q53G45|Q96IV7|Q9H605	ENST00000369405.3	37	CCDS7574.1	.	.	.	.	.	.	.	.	.	.	C	13.98	2.399861	0.42512	0.0	1.16E-4	ENSG00000023041	ENST00000369405;ENST00000369404	T;T	0.08634	3.07;3.07	5.87	2.0	0.26442	Src homology-3 domain (1);Variant SH3 (1);	0.053590	0.85682	D	0.000000	T	0.10208	0.0250	M	0.62723	1.935	0.41894	D	0.990388	B;B	0.18013	0.025;0.018	B;B	0.12837	0.007;0.008	T	0.08166	-1.0735	10	0.45353	T	0.12	-0.9313	10.9445	0.47294	0.0:0.7482:0.0:0.2518	.	313;317	Q9H6R6-2;Q9H6R6	.;ZDHC6_HUMAN	H	317;313	ENSP00000358413:R317H;ENSP00000358412:R313H	ENSP00000358412:R313H	R	-	2	0	ZDHHC6	114182265	1.000000	0.71417	0.995000	0.50966	0.932000	0.56968	2.915000	0.48805	0.186000	0.20125	0.655000	0.94253	CGC	ZDHHC6-001	KNOWN	basic|appris_candidate_longest|CCDS	protein_coding	protein_coding	OTTHUMT00000050393.1		-6.323927	0	1	89	0	0	1	0	NM_022494	3	6.561881	57	0.050000
WDR90	197335	broad.mit.edu	hg19	16	708649	708649	+	Missense_Mutation	SNP	C	C	G			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr16:708649C>G	ENST00000549091.1	+	23	2983	c.2891C>G	c.(2890-2892)cCc>cGc	p.P964R	WDR90_ENST00000293879.4_Missense_Mutation_p.P964R	NM_145294.4	NP_660337.3	Q96KV7	WDR90_HUMAN	WD repeat domain 90	964					endometrium(4)|kidney(3)|large_intestine(2)|lung(22)|ovary(2)|prostate(1)|skin(1)|urinary_tract(2)	37		Hepatocellular(780;0.0218)			AGCCCAGGCCCCCAGGTGTGT	0.692	0	20.0	24.0	23.0	16	708649	2010	4142	6152	SO:0001583	missense	AB067511	CCDS42092.1	16p13.3	2013-01-09			ENSG00000161996	ENSG00000161996	"""WD repeat domain containing"""	26960	protein-coding gene	gene with protein product			"""chromosome 16 open reading frame 17"", ""chromosome 16 open reading frame 15"", ""chromosome 16 open reading frame 16"", ""chromosome 16 open reading frame 19"", ""chromosome 16 open reading frame 18"""	C16orf17, C16orf15, C16orf16, C16orf19, C16orf18	11572484, 11157797	Standard	XM_005255160	Approved	FLJ36483, KIAA1924	uc002cii.1	Q96KV7	OTTHUMG00000048040	ENST00000293879.4:c.2891C>G	16.37:g.708649C>G	ENSP00000293879:p.Pro964Arg	Q0VA87|Q0VA88|Q6P048|Q6ZMS1|Q6ZTH1|Q8N202|Q8N221|Q8NBB8|Q96PW4|Q96S18	ENST00000293879.4	37	CCDS42092.1	.	.	.	.	.	.	.	.	.	.	C	7.176	0.588597	0.13812	.	.	ENSG00000161996	ENST00000549091;ENST00000293879	T;T	0.48836	0.8;3.52	5.24	1.95	0.26073	WD40/YVTN repeat-like-containing domain (1);WD40 repeat-like-containing domain (1);	0.427951	0.23220	U	0.050579	T	0.24812	0.0602	N	0.12663	0.25	0.80722	D	1	P;P	0.48503	0.911;0.91	P;P	0.44897	0.461;0.463	T	0.05289	-1.0894	10	0.25106	T	0.35	.	1.9304	0.03326	0.117:0.1596:0.4683:0.2551	.	964;964	F8VUX9;Q96KV7	.;WDR90_HUMAN	R	964	ENSP00000448122:P964R;ENSP00000293879:P964R	ENSP00000293879:P964R	P	+	2	0	WDR90	648650	0.989000	0.36119	0.714000	0.30535	0.417000	0.31264	1.683000	0.37638	0.602000	0.29896	0.655000	0.94253	CCC	WDR90-002	NOVEL	basic|appris_candidate|CCDS	protein_coding	protein_coding	OTTHUMT00000404335.1		26.669676	0	-1	32	0	0	1	0	NM_145294	9	26.907726	14	0.391304
SF3B1	23451	broad.mit.edu	hg19	2	198267484	198267484	+	Missense_Mutation	SNP	G	G	A			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr2:198267484G>A	ENST00000335508.6	-	14	1964	c.1873C>T	c.(1873-1875)Cgt>Tgt	p.R625C		NM_012433.2	NP_036565.2	O75533	SF3B1_HUMAN	splicing factor 3b, subunit 1, 155kDa			nuclear mRNA splicing, via spliceosome	catalytic step 2 spliceosome|nuclear speck|U12-type spliceosomal complex	protein binding	NS(35)|breast(10)|central_nervous_system(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(524)|kidney(4)|large_intestine(10)|lung(19)|ovary(1)|pancreas(4)|prostate(6)|salivary_gland(1)|skin(4)|testis(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	633			OV - Ovarian serous cystadenocarcinoma(117;0.246)		GTTGTGTTACGGACATACTCA	0.433	5	93.0	90.0	91.0	2	198267484	2203	4300	6503	SO:0001583	missense	AF054284	CCDS33356.1, CCDS46479.1	2q33.1	2014-09-17	2002-08-29		ENSG00000115524	ENSG00000115524		10768	protein-coding gene	gene with protein product		605590	"""splicing factor 3b, subunit 1, 155kD"""		9585501	Standard	XM_005246428	Approved	SAP155, SF3b155, PRPF10, Prp10, Hsh155	uc002uue.3	O75533	OTTHUMG00000154447	ENST00000335508.6:c.1873C>T	2.37:g.198267484G>A	ENSP00000335321:p.Arg625Cys	E9PCH3	ENST00000335508.6	37	CCDS33356.1	.	.	.	.	.	.	.	.	.	.	G	19.68	3.873082	0.72180	.	.	ENSG00000115524	ENST00000335508	T	0.74421	-0.84	5.82	4.93	0.64822	Armadillo-like helical (1);Armadillo-type fold (1);	0.053241	0.64402	D	0.000001	D	0.90331	0.6975	H	0.96333	3.805	0.80722	D	1	D	0.89917	1.0	D	0.79784	0.993	D	0.93337	0.6706	10	0.87932	D	0	.	15.2676	0.73675	0.0:0.0:0.7451:0.2549	.	625	O75533	SF3B1_HUMAN	C	625	ENSP00000335321:R625C	ENSP00000335321:R625C	R	-	1	0	SF3B1	197975729	1.000000	0.71417	1.000000	0.80357	0.995000	0.86356	4.689000	0.61723	1.444000	0.47605	-0.182000	0.12963	CGT	SF3B1-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000335245.2		58.251050	0	1	55	0	0	1	0		18	58.251050	18	0.500000
PPP2R1B	5519	broad.mit.edu	hg19	11	111636064	111636064	+	Silent	SNP	T	T	C			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr11:111636064T>C	ENST00000527614.1	-	2	224	c.159A>G	c.(157-159)gcA>gcG	p.A53A	PPP2R1B_ENST00000341980.6_Silent_p.A53A|PPP2R1B_ENST00000393055.2_Silent_p.A53A|PPP2R1B_ENST00000427203.2_5'UTR|PPP2R1B_ENST00000426998.2_Intron|PPP2R1B_ENST00000311129.5_Silent_p.A53A	NM_001177562.1|NM_002716.4	NP_001171033.1|NP_002707.3	P30154	2AAB_HUMAN	protein phosphatase 2, regulatory subunit A, beta	53				protein binding	endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(2)|liver(1)|lung(10)|prostate(1)|urinary_tract(2)	22		all_cancers(61;2.34e-15)|all_epithelial(67;1.72e-09)|Melanoma(852;1.91e-06)|all_hematologic(158;0.000405)|Acute lymphoblastic leukemia(157;0.000967)|Breast(348;0.0112)|all_neural(223;0.0281)|Medulloblastoma(222;0.0425)		BRCA - Breast invasive adenocarcinoma(274;1.13e-06)|Epithelial(105;2.36e-06)|all cancers(92;3.78e-05)|OV - Ovarian serous cystadenocarcinoma(223;0.0761)	CTACTCCAAGTGCTAGGGCAA	0.373	0	122.0	122.0	122.0	11	111636064	2201	4297	6498	SO:0001819	synonymous_variant	AF087438	CCDS8348.1, CCDS8349.1, CCDS53706.1, CCDS53707.1, CCDS53708.1	11q23.1	2010-06-18	2010-04-14		ENSG00000137713	ENSG00000137713	"""Serine/threonine phosphatases / Protein phosphatase 2, regulatory subunits"""	9303	protein-coding gene	gene with protein product	"""PP2A-A-beta"", ""protein phosphatase 2A, regulatory subunit A, beta isoform"""	603113	"""protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform"", ""protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform"""		2159327, 9795170	Standard	NM_181699	Approved	PR65B, PP2A-Abeta	uc001plw.1	P30154	OTTHUMG00000166741	ENST00000341980.6:c.159A>G	11.37:g.111636064T>C		A8MY67|B0YJ69|B4DGQ6|B4DK91|B4DWW5|F8W8G1|O75620|Q8NHV8	ENST00000341980.6	37	CCDS53708.1																																																																																			PPP2R1B-005	NOVEL	basic|exp_conf|CCDS	protein_coding	protein_coding	OTTHUMT00000391300.1		162.795980	0	-8	154	0	0	1	0	NM_002716	52	162.798076	53	0.495238
CYP1A1	1543	broad.mit.edu	hg19	15	75015195	75015195	+	Missense_Mutation	SNP	G	G	T			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr15:75015195G>T	ENST00000379727.3	-	2	442	c.244C>A	c.(244-246)Ccc>Acc	p.P82T	CYP1A1_ENST00000564596.1_Intron|CYP1A1_ENST00000395048.2_Missense_Mutation_p.P82T|CYP1A1_ENST00000395049.4_Missense_Mutation_p.P82T|CYP1A1_ENST00000567032.1_Missense_Mutation_p.P82T			P04798	CP1A1_HUMAN	cytochrome P450, family 1, subfamily A, polypeptide 1	82		cellular lipid metabolic process|drug metabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|microsome	aromatase activity|electron carrier activity|heme binding|oxygen binding|vitamin D 24-hydroxylase activity	autonomic_ganglia(1)|breast(2)|endometrium(1)|large_intestine(7)|lung(13)|ovary(3)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	34					ACCACCACGGGTGTGGAGCCA	0.627	0	57.0	49.0	52.0	15	75015195	2197	4296	6493	SO:0001583	missense	BC023019	CCDS10268.1	15q24.1	2007-12-14	2003-01-14		ENSG00000140465	ENSG00000140465	"""Cytochrome P450s"""	2595	protein-coding gene	gene with protein product		108330	"""cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1"""	CYP1	15128046	Standard	NM_000499	Approved	P450DX, P1-450, P450-C, CP11	uc002ayp.4	P04798	OTTHUMG00000142812	ENST00000395049.4:c.244C>A	15.37:g.75015195G>T	ENSP00000378489:p.Pro82Thr	A4F3V9|A4F3W0|Q53G18	ENST00000395049.4	37		.	.	.	.	.	.	.	.	.	.	G	15.03	2.712417	0.48517	.	.	ENSG00000140465	ENST00000379727;ENST00000395048;ENST00000395049;ENST00000268062	T;T;T	0.80994	-1.44;-1.44;-1.44	5.23	5.23	0.72850	.	0.000000	0.85682	D	0.000000	D	0.90140	0.6919	M	0.86268	2.805	0.58432	D	0.999999	D;D	0.89917	1.0;1.0	D;D	0.97110	1.0;1.0	D	0.91531	0.5242	10	0.87932	D	0	.	14.1323	0.65263	0.0747:0.0:0.9253:0.0	.	82;82	E7EMT5;P04798	.;CP1A1_HUMAN	T	82	ENSP00000369050:P82T;ENSP00000378488:P82T;ENSP00000378489:P82T	ENSP00000268062:P82T	P	-	1	0	CYP1A1	72802248	1.000000	0.71417	0.077000	0.20336	0.301000	0.27625	6.592000	0.74095	2.432000	0.82394	0.462000	0.41574	CCC	CYP1A1-003	NOVEL	basic|exp_conf	protein_coding	protein_coding	OTTHUMT00000421250.1		51.976513	1	12	52	0	1.5739e-10	1	1.73957e-10	NM_000499	17	52.164169	12	0.586207
VPS13D	55187	broad.mit.edu	hg19	1	12328815	12328815	+	Silent	SNP	G	G	A			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr1:12328815G>A	ENST00000358136.3	+	16	1984	c.1854G>A	c.(1852-1854)gcG>gcA	p.A618A	VPS13D_ENST00000356315.4_Silent_p.A618A	NM_015378.2	NP_056193.2	Q5THJ4	VP13D_HUMAN	vacuolar protein sorting 13 homolog D (S. cerevisiae)	618		protein localization			NS(1)|breast(6)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(13)|large_intestine(28)|lung(44)|ovary(5)|pancreas(1)|prostate(8)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(4)	130	Ovarian(185;0.249)	Lung NSC(185;4.08e-05)|all_lung(284;4.55e-05)|Renal(390;0.000147)|Colorectal(325;0.00058)|Breast(348;0.00093)|Ovarian(437;0.00965)|Hepatocellular(190;0.0202)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0327)|Colorectal(212;4.63e-06)|BRCA - Breast invasive adenocarcinoma(304;0.000289)|COAD - Colon adenocarcinoma(227;0.000801)|Kidney(185;0.00216)|KIRC - Kidney renal clear cell carcinoma(229;0.00544)|STAD - Stomach adenocarcinoma(313;0.012)|READ - Rectum adenocarcinoma(331;0.0476)|Lung(427;0.209)	GAAATCCGGCGCACAGCCACT	0.453	0	151.0	161.0	158.0	1	12328815	2203	4300	6503	SO:0001819	synonymous_variant	AJ608774	CCDS30588.1, CCDS30589.1	1p36.21	2008-02-05	2006-04-04		ENSG00000048707	ENSG00000048707		23595	protein-coding gene	gene with protein product		608877	"""vacuolar protein sorting 13D (yeast)"""			Standard	NM_015378	Approved	FLJ10619, KIAA0453	uc001atv.3	Q5THJ4	OTTHUMG00000013155	ENST00000358136.3:c.1854G>A	1.37:g.12328815G>A			ENST00000358136.3	37	CCDS30588.1																																																																																			VPS13D-001	KNOWN	basic|appris_candidate_longest|CCDS	protein_coding	protein_coding	OTTHUMT00000036897.2		-31.639576	0	-1	215	0	0	1	0	NM_015378	4	6.666791	150	0.025974
ARID1B	57492	broad.mit.edu	hg19	6	157222625	157222625	+	Missense_Mutation	SNP	C	C	A			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr6:157222625C>A	ENST00000346085.5	+	4	1893	c.1892C>A	c.(1891-1893)cCg>cAg	p.P631Q	ARID1B_ENST00000275248.4_Missense_Mutation_p.P560Q|ARID1B_ENST00000350026.5_Missense_Mutation_p.P618Q|ARID1B_ENST00000367148.1_Missense_Mutation_p.P618Q	NM_020732.3	NP_065783.3	Q8NFD5	ARI1B_HUMAN	AT rich interactive domain 1B (SWI1-like)	618	Gln-rich.	chromatin-mediated maintenance of transcription|nervous system development|transcription, DNA-dependent	SWI/SNF complex	DNA binding|protein binding|transcription coactivator activity	NS(2)|breast(5)|central_nervous_system(4)|endometrium(12)|kidney(4)|large_intestine(11)|lung(30)|ovary(3)|pancreas(1)|prostate(4)|skin(2)|urinary_tract(3)	81		Breast(66;0.000162)|Ovarian(120;0.0265)		OV - Ovarian serous cystadenocarcinoma(65;3.19e-17)|BRCA - Breast invasive adenocarcinoma(81;1.01e-05)	CAGTATCTGCCGTCCCAGTCC	0.642	0	31.0	31.0	31.0	6	157222625	2203	4300	6503	SO:0001583	missense	AF521671	CCDS5251.1, CCDS5251.2, CCDS55072.1	6q25.3	2014-09-17			ENSG00000049618	ENSG00000049618	"""-"""	18040	protein-coding gene	gene with protein product		614556				Standard	NM_017519	Approved	KIAA1235, ELD/OSA1, p250R, BAF250b, DAN15, 6A3-5	uc003qqo.3	Q8NFD5	OTTHUMG00000015890	ENST00000346085.5:c.1892C>A	6.37:g.157222625C>A	ENSP00000344546:p.Pro631Gln	Q5JRD1|Q5VYC4|Q8IZY8|Q8TEV0|Q8TF02|Q99491|Q9ULI5	ENST00000346085.5	37	CCDS55072.1	.	.	.	.	.	.	.	.	.	.	C	13.16	2.154173	0.38021	.	.	ENSG00000049618	ENST00000346085;ENST00000350026;ENST00000367148;ENST00000275248;ENST00000354354;ENST00000414678;ENST00000319584	T;T;T;T;T;T	0.17213	4.63;4.5;4.63;4.59;4.27;2.29	5.71	4.81	0.61882	.	0.197343	0.30762	N	0.008934	T	0.02230	0.0069	N	0.02539	-0.55	0.22811	N	0.9987	B;B;B	0.06786	0.0;0.001;0.001	B;B;B	0.08055	0.001;0.003;0.003	T	0.41233	-0.9520	10	0.30854	T	0.27	.	11.6579	0.51328	0.184:0.816:0.0:0.0	.	618;631;560	Q8NFD5;Q8NFD5-2;G3XAA0	ARI1B_HUMAN;.;.	Q	631;618;618;560;39;117;40	ENSP00000344546:P631Q;ENSP00000055163:P618Q;ENSP00000356116:P618Q;ENSP00000275248:P560Q;ENSP00000412835:P117Q;ENSP00000313006:P40Q	ENSP00000275248:P560Q	P	+	2	0	ARID1B	157264317	0.303000	0.24463	0.576000	0.28549	0.990000	0.78478	1.365000	0.34182	1.354000	0.45846	0.655000	0.94253	CCG	ARID1B-001	KNOWN	basic|appris_candidate|CCDS	protein_coding	protein_coding	OTTHUMT00000042827.3		30.418793	1	1	25	0	0.000274275	1	0.000274275	NM_020732	8	30.414888	0	1.000000
SEC24B	10427	broad.mit.edu	hg19	4	110447472	110447472	+	Missense_Mutation	SNP	C	C	T			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr4:110447472C>T	ENST00000265175.5	+	17	2937	c.2882C>T	c.(2881-2883)gCg>gTg	p.A961V	SEC24B_ENST00000399100.2_Missense_Mutation_p.A926V|SEC24B_ENST00000504968.2_Missense_Mutation_p.A991V	NM_006323.2	NP_006314.2	O95487	SC24B_HUMAN	SEC24 family member B	961		COPII vesicle coating|intracellular protein transport|post-translational protein modification|protein N-linked glycosylation via asparagine	COPII vesicle coat|cytosol|endoplasmic reticulum membrane|Golgi membrane|perinuclear region of cytoplasm	protein binding|transporter activity|zinc ion binding	breast(1)|endometrium(7)|kidney(1)|large_intestine(10)|lung(12)|ovary(2)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;3.03e-05)	GCTGGATTTGCGGTGCAGTTG	0.363	0	174.0	158.0	163.0	4	110447472	1862	4089	5951	SO:0001583	missense	AJ131245	CCDS43260.1, CCDS47124.1, CCDS75179.1	4q25	2013-10-21	2013-10-21		ENSG00000138802	ENSG00000138802		10704	protein-coding gene	gene with protein product		607184	"""SEC24 (S. cerevisiae) related gene family, member B"", ""SEC24 family, member B (S. cerevisiae)"""		10075675, 10329445	Standard	XM_005262688	Approved		uc003hzk.3	O95487	OTTHUMG00000161372	ENST00000504968.2:c.2972C>T	4.37:g.110447472C>T	ENSP00000428564:p.Ala991Val	B7ZKM8|B7ZKN4|Q0VG08	ENST00000504968.2	37		.	.	.	.	.	.	.	.	.	.	C	35	5.421208	0.96111	.	.	ENSG00000138802	ENST00000504968;ENST00000399100;ENST00000265175	T;T;T	0.77098	-1.07;-1.07;-1.07	5.3	5.3	0.74995	Sec23/Sec24 beta-sandwich (1);	0.049795	0.85682	D	0.000000	D	0.84397	0.5463	L	0.46567	1.45	0.80722	D	1	D;D;D;D;D	0.89917	1.0;1.0;1.0;1.0;1.0	D;D;D;D;D	0.66716	0.946;0.942;0.946;0.911;0.946	T	0.82989	-0.0183	10	0.39692	T	0.17	-20.8388	19.3486	0.94374	0.0:1.0:0.0:0.0	.	875;560;991;926;961	B4DTM6;B4E2E1;B7ZKM8;O95487-2;O95487	.;.;.;.;SC24B_HUMAN	V	991;926;961	ENSP00000428564:A991V;ENSP00000382051:A926V;ENSP00000265175:A961V	ENSP00000265175:A961V	A	+	2	0	SEC24B	110666921	1.000000	0.71417	1.000000	0.80357	0.967000	0.64934	7.818000	0.86416	2.644000	0.89710	0.655000	0.94253	GCG	SEC24B-003	NOVEL	basic|appris_candidate_longest|exp_conf	protein_coding	protein_coding	OTTHUMT00000364695.2		-6.176324	0	-10	116	0	0	1	0		3	6.387115	56	0.050847
GNAQ	2776	broad.mit.edu	hg19	9	80409488	80409488	+	Missense_Mutation	SNP	T	T	G	rs121913492		TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr9:80409488T>G	ENST00000286548.4	-	5	848	c.626A>C	c.(625-627)cAa>cCa	p.Q209P	GNAQ_ENST00000397476.3_Missense_Mutation_p.Q7P	NM_002072.3	NP_002063.2	P50148	GNAQ_HUMAN	guanine nucleotide binding protein (G protein), q polypeptide	209		activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity by dopamine receptor signaling pathway|glutamate signaling pathway|negative regulation of protein kinase activity|platelet activation|protein ADP-ribosylation|protein stabilization|regulation of action potential|regulation of catenin import into nucleus	cytoplasm|heterotrimeric G-protein complex	G-protein beta/gamma-subunit complex binding|G-protein-coupled receptor binding|GTP binding|GTPase activator activity|GTPase activity|signal transducer activity	NS(1)|endometrium(3)|eye(229)|kidney(1)|large_intestine(4)|lung(6)|meninges(11)|ovary(1)|prostate(1)|skin(44)|upper_aerodigestive_tract(1)	302					CTCTGACCTTTGGCCCCCTAC	0.348	153	108.0	105.0	106.0	9	80409488	2203	4300	6503	SO:0001583	missense		CCDS6658.1	9q21	2010-03-17			ENSG00000156052	ENSG00000156052		4390	protein-coding gene	gene with protein product		600998			8825633	Standard	NM_002072	Approved	G-ALPHA-q, GAQ	uc004akw.3	P50148	OTTHUMG00000020059	ENST00000286548.4:c.626A>C	9.37:g.80409488T>G	ENSP00000286548:p.Gln209Pro	O15108|Q13462|Q6NT27|Q92471|Q9BZB9	ENST00000286548.4	37	CCDS6658.1	.	.	.	.	.	.	.	.	.	.	T	25.2	4.614273	0.87359	.	.	ENSG00000156052	ENST00000286548;ENST00000397476	D;D	0.91237	-2.81;-2.81	5.69	5.69	0.88448	.	0.000000	0.85682	D	0.000000	D	0.97164	0.9073	H	0.97291	3.975	0.80722	D	1	D	0.76494	0.999	D	0.85130	0.997	D	0.98607	1.0661	10	0.87932	D	0	.	15.9502	0.79827	0.0:0.0:0.0:1.0	.	209	P50148	GNAQ_HUMAN	P	209;7	ENSP00000286548:Q209P;ENSP00000443197:Q7P	ENSP00000286548:Q209P	Q	-	2	0	GNAQ	79599308	1.000000	0.71417	0.999000	0.59377	0.995000	0.86356	8.040000	0.89188	2.167000	0.68274	0.460000	0.39030	CAA	GNAQ-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000052761.1		97.542393	0	-22	90	0	0	1	0	NM_002072	30	97.853137	40	0.428571
ZNRD1-AS1	0	broad.mit.edu	hg19	6	29976059	29976059	+	RNA	SNP	T	T	C			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr6:29976059T>C	ENST00000376797.3	-	0	1053				ZNRD1-AS1_ENST00000420251.1_RNA|ZNRD1-AS1_ENST00000425604.1_RNA|ZNRD1-AS1_ENST00000448093.1_RNA|HLA-J_ENST00000462773.1_RNA																	GGAGATCACATTGACCTGGCA	0.612	0											AF032110		6p21.33	2014-08-14	2012-08-15	2010-11-25	ENSG00000204623	ENSG00000204623	"""Long non-coding RNAs"""	13924	non-coding RNA	RNA, long non-coding		615714	"""chromosome 6 open reading frame 12"", ""non-protein coding RNA 171"", ""ZNRD1 antisense RNA (non-protein coding)"", ""ZNRD1 antisense RNA 1 (non-protein coding)"""	C6orf12, NCRNA00171, ZNRD1AS, ZNRD1-AS	9553157, 11130983, 25110835	Standard	NR_026751	Approved	HTEX4, Em:AB023056.3	uc003rto.3	Q2KJ03	OTTHUMG00000031109		6.37:g.29976059T>C			ENST00000376797.3	37																																																																																				ZNRD1-AS1-006	KNOWN	basic|exp_conf	antisense	antisense	OTTHUMT00000253083.1		-10.867521	0	-1	62	0	0	1	0	NR_026751	4	9.385408	87	0.043956
FMNL3	91010	broad.mit.edu	hg19	12	50045720	50045720	+	Frame_Shift_Del	DEL	T	T	-			TCGA-VD-A8K9-01A-11D-A39W-08	TCGA-VD-A8K9-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	23cbfdd9-1deb-402a-968c-6cf0fb8d5e4a	bd4e9dce-2a02-49c6-9d80-616cd900626b	g.chr12:50045720delT	ENST00000335154.5	-	14	1832	c.1599delA	c.(1597-1599)ttafs	p.L533fs	FMNL3_ENST00000550488.1_Frame_Shift_Del_p.L533fs|FMNL3_ENST00000293590.5_Frame_Shift_Del_p.L533fs|FMNL3_ENST00000352151.5_Frame_Shift_Del_p.L482fs	NM_175736.4	NP_783863.4	Q8IVF7	FMNL3_HUMAN	formin-like 3	533	Pro-rich.	actin cytoskeleton organization		actin binding|Rho GTPase binding	breast(4)|endometrium(7)|kidney(2)|large_intestine(6)|lung(11)|ovary(2)|pancreas(2)|prostate(2)|skin(2)|stomach(1)	39					GGTTACCTGGTAATGGGGGAG	0.632	0	11.0	14.0	13.0	12	50045720	1909	4106	6015	SO:0001589	frameshift_variant	AK128195	CCDS41780.1, CCDS44874.1	12q13.12	2006-04-10						23698	protein-coding gene	gene with protein product					12684686	Standard	NM_198900	Approved	DKFZp762B245, MGC45819, WBP3	uc001ruv.1	Q8IVF7	OTTHUMG00000169651	ENST00000352151.5:c.1446delA	12.37:g.50045720delT	ENSP00000344311:p.Leu482fs	B0JZA7|Q6ZRJ1	ENST00000352151.5	37	CCDS41780.1																																																																																			FMNL3-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000405279.2	.	.		-3	6					NM_175736	2		4	0.33