E-GEOD-10971
GSE10971
transcription profiling by array
Homo sapiens
Transcription profiling by array of human non-malignant fallopian tube epithelium and high grade serous carcinoma
·发布 2008年6月18日
·更新 2012年2月28日
37
样本数
37
实验数
1
芯片平台
1
相关文献
实验描述
The purpose of this study was to identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the non-malignant fallopian tube epithelium (FTE) of BRCA1/2-mutation carriers, given recent evidence implicating the distal FTE as a common source for SerCa. Experiment Overall Design: We obtained and compared gene expression profiles of laser capture microdissected non-malignant distal FTE from 12 known BRCA1/2-mutation carriers (FTEb) and 12 control women (FTEn) during the luteal and follicular phase, as well as 13 high grade tubal and ovarian SerCa.
参考文献
芯片平台
A-AFFY-44
Affymetrix GeneChip Human Genome U133 Plus 2.0 [HG-U133_Plus_2]（37 例）
样本属性
age
32 year, 36 year, 37 year, 38 year, 39 year, 40 year, 41 year, 42 year, 43 year, 44 year, 45 year, 46 year, 47 year, 48 year, 50 year, 54 year, 55 year, 57 year, 58 year, 59 year
cell type
epithelial
clinical information
menstrual phase: follicular, menstrual phase: luteal, not available
disease state
high grade serous carcinoma, normal
family history
No, Unknown, Yes
genotype
BRCA1 1293del40, BRCA1 185delAG, BRCA1 3875delGTCT, BRCA1 5382insC, BRCA1 917delTT, BRCA1 A1959T, BRCA1 mutation, BRCA1/2 wildtype, BRCA2 6174delT, BRCA2 C5910G, not applicable, Unknown
Organism
Homo sapiens
organism part
oviduct
sex
female
实验信息
登记号
E-GEOD-10971
GEO 编号
GSE10971
实验类型
transcription profiling by array
物种
Homo sapiens
发布日期
2008年6月18日
更新日期
2012年2月28日
提交者
Patricia A. Shaw
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