Transcriptional Profiling of Neuronal APP/APLP2 Double-Conditional Knockout Mice

·Released July 10, 2013 ·Updated July 15, 2015

Samples

Assays

Array Platforms

References

Description

Gene expression analysis of 2-month-old APP/APLP2 double-conditional Knockout (N-dCKO) mice and littermate APLP2 knockout controls, APP knockout and wildtype controls. Mouse hippocampus were dissected for RNA extraction and hybridization on Affymetrix microarrays.

References

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP

Li H, Wang B, Wang Z, Guo Q, Tabuchi K, Hammer RE, Südhof TC, Zheng H

PMID: 20855613

Array Platforms

A-AFFY-45

Affymetrix GeneChip Mouse Genome 430 2.0 [Mouse430_2]（16 items）

Sample Attributes

age

2 month

genotype

APLP2 knockout, APP knockout, APP/APLP2 double conditional knockout, control

organism

Mus musculus

organism part

hippocampus

sex

male

strain

C56/BL6

Experiment Info

Accession

E-GEOD-48622

GEO ID

GSE48622

Type

transcription profiling by array

Organism

Mus musculus

Released

July 10, 2013

Updated

July 15, 2015

Submitter

Baiping Wang

External Links

ArrayExpress source NCBI GEO：GSE48622

Analysis Services

Transcriptional Profiling of Neuronal APP/APLP2 Double-Conditional Knockout Mice

Contact

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