E-MTAB-8398
ERP117622
DNA-seq
Homo sapiens
Kinome and Rho-GTPase Synthetic Lethal shRNA Library Screen in paired NF1-/- and GAP-Related Domain Restored Schwann Cells
Submitted Oct. 24, 2017
·Released Nov. 30, 2019
·Updated Oct. 1, 2019
12
Samples
12
Assays
Description
To identify possible novel targets for the treatment of plexiform neurofibroma formation through a synthetic lethal shRNA library screen in the tumorigenic cell of origin, Schwann cells.
Sample Attributes
cell type
schwann cell
developmental stage
adult
disease
neurofibromatosis, normal
genotype
NF1-/-, NF1-/- with GRD Insertion, wild type genotype
organism
Homo sapiens
organism part
peripheral nervous system
RNA interference
NF1 knockdown by shRNA, none
Experiment Info
Accession
E-MTAB-8398
GEO ID
ERP117622
Type
DNA-seq
Organism
Homo sapiens
Submitted
Oct. 24, 2017
Released
Nov. 30, 2019
Updated
Oct. 1, 2019
Submitter
David W. Clapp
Analysis Services
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