TAF1D (TATA-box binding protein associated factor, RNA polymerase I subunit D)

Gene Basic Information

Gene Basic Information

symbol
TAF1D
locus group
protein-coding gene
location
11q21
gene_family
-
alias symbol
MGC5306|TAF(I)41
alias name
None
entrez id
79101
ensembl gene id
ENSG00000166012
ucsc gene id
uc001ped.5
refseq accession
NM_024116
hgnc_id
HGNC:28759
approved reserved
2005-11-10

Chromosome Location

Chromosome Location

11q21

Gene Summary

Gene Summary

ChineseEnglish

TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009]

OMIM entry for TAF1D     Wikipedia entry for TAF1D

Gene Sequence

Gene Sequence

Nucleotide sequence of TAF1D:[NCBI]
Loading Gene Browser...

Encoded Protein

Encoded Protein

Protein Sequence
1MDKSGIDSLD HVTSDAVELA NRSDNSSDSS LFKTQCIPYS
41PKGEKRNPIR KFVRTPESVH ASDSSSDSSF EPIPLTIKAI
81 FERFKNRKK RYKKKKKRRY QPTGRPRGRP EGRRNPIYSL
121IDKKKQFRSR GSGFPFLESE NEKNAPWRKI LTFEQAVARG
161F FNYIEKLK YEHHLKESLK QMNVGEDLEN EDFDSRRYKF
201LDDDGSISPI EESTAEDEDA THLEDNECDI KLAGDSFIVS
241SE FPVRLSV YLEEEDITEE AALSKKRATK AKNTGQRGLK
281M
Structure predicted by AlphaFold DB(UniProt: Q9H5J8). Color indicates pLDDT confidence (dark blue = high, yellow/orange = low).

Gene Variants

Gene Variants

SNP variants of TAF1D:           Showing partial SNPs
rs623510       rs630648       rs631116       rs644306       rs694699       rs2288505       rs4753498       rs5793653       rs7105804       rs7943266       rs10831095       rs10831096       rs10831097       rs11280945       rs12223322       rs16919267       rs16919288      

Gene Expression

Gene Expression

Tissue expression of TAF1D:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GTAATTATGGGCTGACAGGAC
59
ATCCTCTAAAGAGCTGGAGTC
59
TATTGAGGAGTCAACAGCAG
57
TCAGTCTTACAGGGAATTCAG
57
TATTGAGGAGTCAACAGCAG
57
TCAGTCTTACAGGGAATTCAG
57
GGGTTACAAGCAGCAAGTG
60
TAGGTGAGTAAGGGATACACTG
59
CAACTTTCCCAGAACGCAC
60
GTAATTTGTGAGGCTCAATGC
58
TTTAACGTTTGAGCAAGCTG
58
GCTTCAATGATTCTTTCAGGTG
58
AGTTCAAGACCAGCCTAGG
59
ACATTCATTCCTAAGCGATCAC
59
AGATCCCAAAGATTCTTGGTG
58
TTTGGCTTCTGTCATCTCGT
60
ACACATCTGTACCATTCTTGAG
58
TCTCAATTTGACACCCTCTC
57
GCAACACATCTTGAAGATAACG
58
ACACTCAGTCTTACAGGGA
57

Gene Ontology

Subcellular localization of TAF1D (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for TAF1D:

GO ID
Protein
Source DB
GO:0005668
E9PM59 (UniProtKB)
IEA
GO:0006355
E9PM59 (UniProtKB)
IEA
GO:0003677
Q9H5J8 (UniProtKB)
IEA
GO:0005515
Q9H5J8 (UniProtKB)
IPI
GO:0005515
Q9H5J8 (UniProtKB)
IPI
GO:0005515
Q9H5J8 (UniProtKB)
IPI
GO:0005654
Q9H5J8 (UniProtKB)
IDA
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005654
Q9H5J8 (UniProtKB)
TAS
GO:0005668
Q9H5J8 (UniProtKB)
IEA
GO:0005815
Q9H5J8 (UniProtKB)
IDA
GO:0006355
Q9H5J8 (UniProtKB)
IEA
GO:0006361
Q9H5J8 (UniProtKB)
TAS
GO:0006361
Q9H5J8 (UniProtKB)
TAS
GO:0006362
Q9H5J8 (UniProtKB)
TAS
GO:0006363
Q9H5J8 (UniProtKB)
TAS
GO:0045815
Q9H5J8 (UniProtKB)
TAS

Related microRNA

Related microRNA

microRNAs potentially regulating TAF1D:     

Gene Interactions

Gene Interactions

String
BioGrid
IntAct
mentha
MINT
Reactome
Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Arsenic Poisoning 0.12 1 0 CTD_human
Dermatologic disorders 0.12 1 0 CTD_human

Related Publications

Related Publications

Panomics Integration via Machine Learning Prioritizes TAF1D as a Therapeutic Vulnerability in Lung Adenocarcinoma.
Ding L, Xu Q, Liu D, Wu J, Cai X, Xu F, Ma S, Wang H, Shi Y Hum Mutat IF: 1.8 None
Quantitative mass spectrometry of TATA binding protein-containing complexes and subunit phosphorylations during the cell cycle.
Pijnappel Wwm Pim, Kolkman Annemieke, Baltissen Marijke Pa, Heck Albert, Timmers Ht Marc Proteome Sci IF: 2.360 2011-07-14
Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma.
Sahu Divya, Hsu Chia-Lang, Lin Chen-Ching, Yang Tz-Wen, Hsu Wen-Ming, Ho Shinn-Ying, Juan Hsueh-Fen, Huang Hsuan-Cheng Oncotarget IF: 5.168 0000-00-00

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