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PMID: 10694886 Published · ppublish English

Eukaryotic DNA polymerases, a growing family.

Trends in biochemical sciences ·Vol. 25 ·No. 3 ·2000-05-04

Hübscher U, Nasheuer H P, Syväoja J E

Abstract

In eukaryotic cells, DNA polymerases are required to maintain the integrity of the genome during processes, such as DNA replication, various DNA repair events, translesion DNA synthesis, DNA recombination, and also in regulatory events, such as cell cycle control and DNA damage checkpoint function. In the last two years, the number of known DNA polymerases has increased to at least nine (called alpha, beta, gamma, delta, epsilon, zeta, eta, t and iota), and yeast Saccharomyces cerevisiae contains REV1 deoxycytidyl transferase.

Article Info
Journal
Trends in biochemical sciences
Abbr.
Trends Biochem Sci
Published
2000-05-04
Indexed
2000-05-04
Updated
2006-11-15
Language
English
Country/Region
England
NLM ID
7610674
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