Breast cancer susceptibility-A new look at an old model.

Cancer cell ·第 1 卷 ·第 5 期 ·2002-09-27

Peto Julian

摘要

A polygenic model in which many individually weak genes combine multiplicately to cause a 50-fold range of risk in the population explains several puzzling aspects of familial breast cancer epidemiology, including the very high risk in some families and the failure to identify important new genes since the discovery of BRCA1 and BRCA2.

文献信息

期刊

Cancer cell

期刊简称

Cancer Cell

ISSN

1535-6108

发表日期

2002-09-27

收录日期

2002-07-18

更新日期

2013-11-21

语言

英语

国家/地区

United States

NLM ID

101130617

外部链接

PubMed 原文查看期刊详情

分析服务

Breast cancer susceptibility-A new look at an old model.

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