The BRCA2-EMSY connection: implications for breast and ovarian tumorigenesis.

Cell ·第 115 卷 ·第 5 期 ·2004-01-14

Haber Daniel A

摘要

In this issue, Hughes-Davies et al. describe a novel gene product, EMSY, which suppresses the transactivational activity of BRCA2. EMSY is located within an amplicon in sporadic breast and ovarian cancers, suggesting that its overexpression may mimic the effects of BRCA2 inactivation. The implications for BRCA2 function are discussed.

文献信息

期刊

Cell

期刊简称

Cell

ISSN

0092-8674

发表日期

2004-01-14

收录日期

2003-12-03

更新日期

2005-11-16

语言

英语

国家/地区

United States

NLM ID

0413066

外部链接

PubMed 原文查看期刊详情

分析服务

The BRCA2-EMSY connection: implications for breast and ovarian tumorigenesis.

联系地址

微信公众号