Response to: Pardossi-Piquard et al., "Presenilin-Dependent Transcriptional Control of the Abeta-Degrading Enzyme Neprilysin by Intracellular Domains of betaAPP and APLP." Neuron 46, 541-554.

Amyloid beta-Protein Precursor/metabolism Animals Cells, Cultured Embryo, Mammalian Enzyme Inhibitors/pharmacology Fibroblasts Humans Mice Mice, Knockout Neprilysin/metabolism Presenilins/physiology Protein Structure, Tertiary Transfection

APLP1 protein, human Amyloid beta-Protein Precursor Enzyme Inhibitors Presenilins Neprilysin