Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with primary breast and ovarian cancer.

American journal of obstetrics and gynecology ·Vol. 196 ·No. 4 ·2007-04-20

Spannuth Whitney A, Thaker Premal H, Sood Anil K

Abstract

We describe an unusual Ashkenazi Jewish patient with breast and epithelial ovarian cancer who was found to have simultaneous BRCA1 and BRCA2 mutations (BRCA1 5382insC and BRCA2 6174delT). While these mutations are known to occur individually in Ashkenazi Jewish women, concomitant BRCA1 and BRCA2 mutations in the same individual are rare.

Article Info

Journal

American journal of obstetrics and gynecology

Abbr.

Am J Obstet Gynecol

ISSN

0002-9378

DOI

10.1016/j.ajog.2007.01.026

Published

2007-04-20

Indexed

2007-04-03

Updated

2007-12-03

Language

English

Country/Region

United States

NLM ID

0370476

External Links

PubMed source DOI: 10.1016/j.ajog.2007.01.026 View journal details

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Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with primary breast and ovarian cancer.

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