BRCA1--sowing the seeds crooked in the furrow.

Nature genetics ·Vol. 40 ·No. 1 ·2008-01-18

Foulkes William D

Abstract

Breast tumors with deficiency in DNA double-strand break repair might be expected to show aneuploidy. A new study shows that microdeletions in PTEN, resulting in complete loss of PTEN protein, are signature lesions in these cancers, particularly those arising in BRCA1-mutation carriers.

Article Info

Journal

Nature genetics

Abbr.

Nat Genet

ISSN

1061-4036

DOI

10.1038/ng0108-8

Published

2008-01-18

Indexed

2007-12-28

Updated

2007-12-28

Language

English

Country/Region

United States

NLM ID

9216904

External Links

PubMed source DOI: 10.1038/ng0108-8 View journal details

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BRCA1--sowing the seeds crooked in the furrow.

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