Molecular basis of juvenile myelomonocytic leukemia.

Child Genes, ras Humans Janus Kinases/metabolism Leukemia, Myelomonocytic, Juvenile/diagnosis,genetics,metabolism,therapy Mutation Neurofibromatosis 1/diagnosis Neurofibromin 1/genetics PTEN Phosphohydrolase/metabolism Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics Proto-Oncogene Proteins c-cbl/genetics STAT Transcription Factors/metabolism Signal Transduction ras Proteins/metabolism

Neurofibromin 1 STAT Transcription Factors Proto-Oncogene Proteins c-cbl Janus Kinases PTPN11 protein, human Protein Tyrosine Phosphatase, Non-Receptor Type 11 PTEN Phosphohydrolase ras Proteins