Repair scaffolding reaches new heights at blocked replication forks.

Molecular cell ·Vol. 39 ·No. 2 ·2010-08-20

Downey Michael, Edenberg Ellen R, Toczyski David P

Abstract

In this issue of Molecular Cell, Ohouo et al. (2010) show that Mec1 (hATR) promotes the association of Slx4 and Rtt107 with Dpb11 (hTopBP1) in response to MMS-induced DNA alkylation, suggesting that Slx4 and Rtt107 might coordinate repair factors specifically at damaged replication forks.

Article Info

Journal

Molecular cell

Abbr.

Mol Cell

ISSN

1097-2765

DOI

10.1016/j.molcel.2010.07.007

Published

2010-08-20

Indexed

2010-07-30

Updated

2010-07-30

Language

English

Country/Region

United States

NLM ID

9802571

External Links

PubMed source DOI: 10.1016/j.molcel.2010.07.007 View journal details

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Repair scaffolding reaches new heights at blocked replication forks.

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