The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.

Leukemia ·Vol. 25 ·No. 5 ·2011-05-00 ·页码 874-7

Haferlach C, Bacher U, Haferlach T, Dicker F, Alpermann T, Kern W, Schnittger S

Abstract

暂无摘要

MeSH 主题词

Adolescent Adult Aged Aged, 80 and over Chromosome Inversion Chromosomes, Human, Pair 3/genetics Core Binding Factor Alpha 2 Subunit/genetics Female Genes, ras/genetics Humans Leukemia, Myeloid, Acute/genetics Male Middle Aged Myelodysplastic Syndromes/genetics Neurofibromin 1/genetics Prognosis Proto-Oncogene Proteins/genetics Proto-Oncogene Proteins p21(ras) Survival Rate Translocation, Genetic/genetics Young Adult ras Proteins/genetics

化学物质

Core Binding Factor Alpha 2 Subunit KRAS protein, human Neurofibromin 1 Proto-Oncogene Proteins RUNX1 protein, human Proto-Oncogene Proteins p21(ras) ras Proteins

作者与单位

共 7 位作者，点击展开单位 / ORCID

Haferlach C

Bacher U

Haferlach T

Dicker F

Alpermann T

Kern W

Schnittger S

Article Info

Journal

Leukemia

Abbr.

Leukemia

ISSN

1476-5551

DOI

10.1038/leu.2011.5

Published

2011-05-00

电子出版

2011-00-01

页码

874-7

Language

English

Country/Region

England

NLM ID

8704895

External Links

PubMed source DOI: 10.1038/leu.2011.5 View journal details

Analysis Services

The inv(3)(q21q26)/t(3;3)(q21;q26) is frequently accompanied by alterations of the RUNX1, KRAS and NRAS and NF1 genes and mediates adverse prognosis both in MDS and in AML: a study in 39 cases of MDS or AML.

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