Tracking evolution of BRCA1-associated breast cancer.

Cancer discovery ·Vol. 2 ·No. 6 ·2012-09-28

Jonkers Jos

Abstract

Single-cell profiling and computational identification of evolutionary paths to BRCA1-associated tumorigenesis predict that PTEN loss and TP53 mutation precede loss of wild-type BRCA1 in basal-like and luminal tumors, respectively.

Article Info

Journal

Cancer discovery

Abbr.

Cancer Discov

ISSN

2159-8274

DOI

10.1158/2159-8290.CD-12-0186

Published

2012-09-28

Indexed

2012-06-11

Updated

2016-11-25

Language

English

Country/Region

United States

NLM ID

101561693

External Links

PubMed source DOI: 10.1158/2159-8290.CD-12-0186 View journal details

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Tracking evolution of BRCA1-associated breast cancer.

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