To the rescue: the Fanconi anemia genome stability pathway salvages replication forks.

Cancer cell ·第 22 卷 ·第 1 期 ·2012-09-17

Moldovan George-Lucian, D'Andrea Alan D

摘要

DNA damage can arrest replication forks during S phase. Failure to stabilize and restart arrested forks results in fork collapse and genomic instability. In this issue of Cancer Cell, Schlacher et al. show that the Fanconi anemia and BRCA2 tumor suppressor pathways cooperate to protect stalled replication forks from degradation.

文献信息

期刊

Cancer cell

期刊简称

Cancer Cell

ISSN

1535-6108

发表日期

2012-09-17

收录日期

2012-07-13

更新日期

2016-10-25

语言

英语

国家/地区

United States

NLM ID

101130617

外部链接

PubMed 原文查看期刊详情

分析服务

To the rescue: the Fanconi anemia genome stability pathway salvages replication forks.

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