Hidden dangers: a cryptic exon disrupts BRCA2 mRNA.

Clinical cancer research : an official journal of the American Association for Cancer Research ·第 18 卷 ·第 18 期 ·2013-03-22

Fackenthal James D, Lee Younghee, Olopade Olufunmilayo I

摘要

The first mutation that disrupts BRCA2 mRNA by including a novel, cryptic exon is reported in this issue. The mutation lies deep within an intron and would not have been detected by conventional screening methods. In the future, more mutations may be discovered by direct mRNA analysis.

文献信息

期刊

Clinical cancer research : an official journal of the American Association for Cancer Research

期刊简称

Clin Cancer Res

ISSN

1078-0432

发表日期

2013-03-22

收录日期

2012-09-18

更新日期

2016-10-19

语言

英语

国家/地区

United States

NLM ID

9502500

外部链接

PubMed 原文查看期刊详情

分析服务

Hidden dangers: a cryptic exon disrupts BRCA2 mRNA.

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