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PMID: 23467066 Published · ppublish English

High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy.

Case reports in oncology ·Vol. 6 ·No. 1 ·2013-03-08

Lorusso Domenica, Di Rocco Roberta, Mancini Maria, Raspagliesi Francesco

Abstract

We present the case of a 67-year-old patient with a BRCA1 mutation and breast cancer who underwent prophylactic oophorectomy. After 6 years, an abdominal computed tomography revealed a pelvic mass which proved to be a poorly differentiated serous carcinoma originating from the right residual tube which previously had not been removed during prophylactic surgery. This case report suggests that much effort should be made during prophylactic oophorectomy to completely remove the tubes, especially in light of the recent pathologic theories on the tubal origin of ovarian cancer.

Keywords
BRCA mutation Fallopian tube Kurman's hypothesis Ovarian cancer
Article Info
Journal
Case reports in oncology
Abbr.
Case Rep Oncol
ISSN
1662-6575
Published
2013-03-08
Indexed
2013-03-07
Updated
2013-04-16
Language
English
Country/Region
Switzerland
NLM ID
101517601
External Links
PubMed source
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