Swapping CENP-A at the centromere.

Nature cell biology ·Vol. 15 ·No. 9 ·2013-11-13

French Bradley T, Straight Aaron F

Abstract

Faithful genome segregation depends on the functions of the eukaryotic centromere, which is characterized by the histone variant CENP-A. Gene replacement in human cells and fission yeast has now been used to show how CENP-A biochemically encodes centromere identity, as well as reveal an unexpected role for CENP-B in centromere function.

Article Info

Journal

Nature cell biology

Abbr.

Nat Cell Biol

ISSN

1465-7392

DOI

10.1038/ncb2833

Published

2013-11-13

Indexed

2013-09-03

Updated

2013-09-03

Language

English

Country/Region

England

NLM ID

100890575

External Links

PubMed source DOI: 10.1038/ncb2833 View journal details

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Swapping CENP-A at the centromere.

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