Home LiteratureArticle Details
PMID: 37151013 Published · ppublish chi

[Clinical diagnosis and treatment of optic nerve glioma: a review].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology ·Vol. 59 ·No. 5 ·2023-05-11

Ren TT, Ma JM

Abstract

Optic nerve glioma (ONG) is a relatively rare central nervous system tumor that mainly affects children and adolescents. It can be classified into sporadic and neurofibromatosis type 1 (NF1)-associated types. The histological type is mainly a low-grade pilocytic astrocytoma. The typical clinical manifestations are visual impairment and painless eye protrusion, and the imaging features mainly present as fusiform swelling or irregular masses. Chemotherapy is still the first-line treatment for ONG, and other treatment options include radiotherapy, surgical resection, and molecular targeted therapy. Screening and monitoring of NF1 patients are also crucial. The prognosis of ONG is difficult to predict, and close monitoring and timely effective intervention are necessary.

MeSH 主题词
Child Adolescent Humans Optic Nerve Glioma/diagnosis,therapy,pathology Neurofibromatosis 1/diagnosis,therapy Prognosis Vision, Low
Article Info
Journal
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Abbr.
Zhonghua Yan Ke Za Zhi
ISSN
0412-4081
Published
2023-05-11
Language
chi
Country/Region
China
NLM ID
16210540R
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com