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PMID: 40380173 Published · epublish English

Three-column osteotomy versus Halo-gravity traction combined with posterior column osteotomy in the treatment of dystrophic neurofibromatosis type 1 kyphoscoliosis: a retrospective comparative cohort study.

Journal of orthopaedic surgery and research ·Vol. 20 ·No. 1 ·2025-05-16

Lo YS, Dai YT, Qiu Y, Lin EE, Hsieh HL, Wei XP, Tsai CH, Fong YC, Chen HT, Tzeng ST, Shi BL

Abstract

Dystrophic neurofibromatosis type I (NF1) kyphoscoliosis presents unique challenges for corrective spinal surgery due to anatomical abnormalities. To compare the radiographic and clinical outcomes of dystrophic neurofibromatosis type 1 (NF1) kyphoscoliosis patients undergoing three-column osteotomy (3CO), halo-gravity traction (HGT), or posterior column osteotomy (PCO) and to evaluate their efficacy and safety in this cohort, different treatment strategies and their associated complication rates warrant further comprehensive investigation. Dystrophic NF1 kyphoscoliosis were divided into 3CO, HGT, and PCO groups based on the surgical strategy. Radiographic parameters were measured preoperatively, postoperatively, and at each follow-up. Intraoperative and postoperative complications were recorded for each patient, and patient-reported outcomes were assessed using the Scoliosis Research Society-22 (SRS-22) questionnaire. Differences among the three groups were analyzed. A total of 9 patients were included in the 3CO, 22 in HGT group, 95 in PCO groups, respectively. Significant differences among the three groups were found in terms of operation time (p = 0.011), estimated blood loss (p = 0.003), and number of satellite rod techniques (p = 0.013). At pre-operation, the Cobb angles of main curves were 84.3 ± 24.6° in 3CO group, 99.1 ± 24.3° in HGT group, 60.0 ± 16.8° in PCO group. At post-operation, significant post-operative improvements were found in the Cobb angles of the main curves, apical vertebral translation (AVT), segmental kyphosis (SK), and deformity angular ratio (DAR) in all three groups (p < 0.001). No significant correction loss was observed during the follow-up. Six complications were found in the 3CO group, 13 in the HGT group, and 40 in the PCO group. PCO, 3CO, and HGT could be applied to dystrophic NF1 patients. The 3CO is also associated with increased perioperative complications. IV.

Keywords
Halo-gravity traction Kyphoscoliosis Neurofibromatosis type 1 Posterior column osteotomy Three-column osteotomy
MeSH 主题词
Humans Kyphosis/surgery,diagnostic imaging,etiology Scoliosis/surgery,diagnostic imaging,etiology Female Male Retrospective Studies Neurofibromatosis 1/complications,diagnostic imaging,surgery Osteotomy/methods Traction/methods Adolescent Treatment Outcome Cohort Studies Child Young Adult Adult
Article Info
Journal
Journal of orthopaedic surgery and research
Abbr.
J Orthop Surg Res
ISSN
1749-799X
Published
2025-05-16
Language
English
Country/Region
England
NLM ID
101265112
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