Lights genes action: Video strategy for BRCA1/2 patient education.

Pathogenic variants (PVs) in the BRCA1 and BRCA2 ( BRCA1/2) genes increase lifetime risk of several cancers including breast and ovarian. Communicating complex genetic risk and management strategies can be challenging. Digital education tools, like short videos, can provide standardized, accessible information to support patient understanding and family communication. A short educational video reviewing BRCA1/2-associated cancer risks, guideline-based screening, and risk-reduction strategies was developed using National Comprehensive Cancer Network (NCCN) recommendations in patient-centered language. From July-August 2024, patients with known BRCA1/2 PVs attending a gynecologic oncology clinic were offered video access via a QR code and invited to complete a voluntary survey assessing usability, satisfaction, perceived usefulness, trustworthiness, and potential value for family communication. Survey responses were summarized descriptively. Of 34 patients offered the video, 32 (94%) viewed it, of which 28 (88%) completed the survey. Median age of participants was 43 years (interquartile range, [IQR]: 35-60 years). All participants were female, 68% White, 11% Hispanic or Latino, 46% BRCA1 PVs, and 54% BRCA2 PVs. Most participants rated the video as very easy to use (96%), very understandable (96%), and satisfying (86%), with 79% finding the content useful and 64% finding the video helpful for communicating risk with relatives. Qualitative feedback highlighted clarity and usefulness for newly diagnosed individuals. These findings suggest that a brief educational video on BRCA1/2 risk was feasible, highly acceptable, and perceived as useful by participants. Video-based education may serve as an effective adjunct to clinical counseling and facilitate communication of hereditary cancer risk with relatives.