The goal of this experiment was to investigate the role of the FBXO38 ubiquitin ligase in the regulation of centromeric ...
We performed single-cell RNA-Seq to determine the effects of CENP-A overexpression and p53 status on cell fate over time...
We performed bulk RNA-Seq to investigate global transcriptional changes upon overexpression of the centromeric H3 varian...
To unravel the fine architecture of neocentromeres found in three well-differentiated liposarcoma (WDLPS) cell lines as ...
CENP-A is a centromere-specific histone 3 variant essential for centromere specification. CENP-A partially replaces cano...
Organisms invest significant effort into maintaining genome stability. However, in diverse groups of eukaryotes, portio...
The molecular mechanism responsible for cell fate after mitotic slippage is unclear. We investigate the postmitotic effe...
We employ the well-studied fission yeast centromere to investigate the function of the CENP-A (Cnp1) N-tail. We show tha...
Specialized chromatin containing CENP-A nucleosomes instead of H3 nucleosomes is found at all centromeres. However, the ...
Comparison of histone variant CENP-A in different cell lines vs. DHS profiles from same cell lines. Mock IPs included. P...
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