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ZXDA/B and CENP-A/B Chromatin immunoprecipitation sequencing (ChIP-seq) in hu...

样本量:14 物种:Homo sapiens, Homo sapiens 类型:ChIP-seq 2022年6月15日

The goal of this experiment was to investigate the role of the FBXO38 ubiquitin ligase in the regulation of centromeric ...

Single-cell RNA-Seq to study the effects of acute and chronic CENP-A overexpr...

样本量:6 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA from single cel... 2021年3月1日

We performed single-cell RNA-Seq to determine the effects of CENP-A overexpression and p53 status on cell fate over time...

Bulk RNA-Seq to study the effects of CENP-A overexpression, p53 status, and X...

样本量:30 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA, Cell line - Hi... 2021年3月1日

We performed bulk RNA-Seq to investigate global transcriptional changes upon overexpression of the centromeric H3 varian...

Giant marker chromosomes in cancer

样本量:4 物种:Homo sapiens 类型:genotyping by array 2017年12月22日

To unravel the fine architecture of neocentromeres found in three well-differentiated liposarcoma (WDLPS) cell lines as ...

Ccp1 homodimer mediates chromatin integrity by antagonizing CENP-A loading

样本量:3 物种:Schizosaccharomyces pombe 类型:ChIP-seq 2016年8月4日

CENP-A is a centromere-specific histone 3 variant essential for centromere specification. CENP-A partially replaces cano...

CENP-A Deposition Defines Sequences for Retention and Elimination during Prog...

样本量:62 物种:Ascaris suum 类型:ChIP-seq 2016年7月15日

Organisms invest significant effort into maintaining genome stability. However, in diverse groups of eukaryotes, portio...

Expression data in HeLa cells treated with CENP-E siRNA or Eg5 siRNA in the p...

样本量:8 物种:Homo sapiens 类型:transcription profiling by array 2015年6月25日

The molecular mechanism responsible for cell fate after mitotic slippage is unclear. We investigate the postmitotic effe...

The N-terminal Tail of CENP-A Confers Epigenetic Stability to Centromeres via...

样本量:4 物种:Schizosaccharomyces pombe 类型:ChIP-seq 2015年4月16日

We employ the well-studied fission yeast centromere to investigate the function of the CENP-A (Cnp1) N-tail. We show tha...

Factors that promote H3 chromatin integrity during transcription prevent prom...

样本量:24 物种:Schizosaccharomyces pombe 类型:ChIP-chip by tiling array 2015年2月19日

Specialized chromatin containing CENP-A nucleosomes instead of H3 nucleosomes is found at all centromeres. However, the ...

Ectopic CENP-A nucleosomes localize to transcription factor hotspots and subt...

样本量:10 物种:Homo sapiens 类型:ChIP-seq 2015年2月3日

Comparison of histone variant CENP-A in different cell lines vs. DHS profiles from same cell lines. Mock IPs included. P...

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