Ras signaling and NF1.

Current opinion in genetics & development ·Vol. 5 ·No. 1 ·1995-02-00 ·页码 51-5

McCormick F

Abstract

The gene responsible for the hereditary disease neurofibromatosis type 1 (NF1) has been well characterized as a regulator of Ras protein activity. Many aspects of the disease seem to be caused by misregulation of Ras as a result of NF1 mutation. Other aspects, however, point at functions for the NF1 protein that have yet to be discovered.

Related Genes

NF1

MeSH 主题词

Animals Genes, Neurofibromatosis 1 Humans Models, Biological Neurofibromatosis 1/genetics Signal Transduction ras Proteins/metabolism

化学物质

ras Proteins

作者与单位

共 1 位作者，点击展开单位 / ORCID

McCormick F

Onyx Pharmaceuticals, Richmond, California 94806, USA.

Article Info

Journal

Current opinion in genetics & development

Abbr.

Curr Opin Genet Dev

ISSN

0959-437X

DOI

10.1016/s0959-437x(95)90053-5

Published

1995-02-00

页码

51-5

Language

English

Country/Region

England

NLM ID

9111375

External Links

PubMed source DOI: 10.1016/s0959-437x(95)90053-5 View journal details

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Ras signaling and NF1.

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