Only about 25% of familial breast cancer is explained by mutations in BRCA1 and BRCA2, fewer by moderate penetrance gene...
Palb2 interacts with BRCA1 and BRCA2 in supercomplexes involved in DNA repair via homologous recombination. Heterozygous...
...Brca1F/F;p53F/F, 62 Brca2F/F;p53F/F and 33 p53F/F mice. For each mouse, tumor DNA was hybridized with its spleen DNA as ...
...Brca1/p53-deficient cell subpopulations
...Brca1F/F;p53F/F, 62 Brca2F/F;p53F/F and 33 p53F/F mice. For each mouse, tumor DNA was hybridized with its spleen DNA as ...
The aim of the experiment was to analyse gene expression profiles in Brca1 tumours arising from different mammary epithe...
...BRCA1, and RAD51, which resulted in greater DNA double-strand breaks and caspase 3 activation following IR treatment. Co...
...BRCA1/2-mutations or carried an UV in either BRCA1/2 A BRCA2-classifier was built using array-CGH profiles of 28 BRCA2-m...
...BRCA1 signatures and resembled basal-like tumors, and basal-B lines displayed mesenchymal and stem-cell characteristics....
...BRCA1 signatures and resembled basal-like tumors, and basal-B lines displayed mesenchymal and stem-cell characteristics....
山东省济南市章丘区文博路2号
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