...BRCA1/BRCA2 mutation or have tumors characterized by homologous recombination deficiency (HRD). We hypothesized that ger...
...BRCA1) and breast cancer gene 2 (BRCA2) are core regulators of the DNA damage homologous recombination repair (HRR) path...
...BRCA1 and BRCA2 genes, which are major contributors to hereditary susceptibility to this malignancy. Although PV carrier...
...BRCA1 and BRCA2 genes are particularly notable, especially in certain populations where founder mutations (specific gene...
...BRCA1, GADD45A, and PD-L1-were dysregulated in the livers of TNBC-bearing mice; however, CDP treatment restored their ex...
...BRCA1/2)-also contribute to hereditary endometrial cancer risk. Recognition of these genetic backgrounds is essential fo...
...BRCA1 (36.8 %) and BRCA2 (25.7 %). The mean knowledge score was 9.42 out of 16 (SD 3.0), with item-level gaps most prono...
...BRCA1/2 mutation carriers, while therapeutic vaccines, particularly for triple-negative breast cancer, stimulate T-cell ...
...BRCA1 mutation rate at 3.03% (4/132) and BRCA2 mutation rate at 6.06% (8/132). Compared with the BRCA wild-type group, t...
Germline testing for BRCA1 and BRCA2 has become integral to the management of breast cancer, with pathogenic variants st...
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