...BRCA1 tumor suppressor locus. Using siRNAs in breast cancer cell lines, we showed that the 17q21.3 amplicon harbored a s...
...BRCA1 mutation carriers, 10 BRCA2 mutation carriers and 43 non-BRCA12 tumors denominated hereafter as BRCAX tumors. In a...
...BRCA1- or BRCA2-mutated, or BRCAX, i.e. familial cases with no mutations in BRCA1 or BRCA2 genes) and sporadic breast ca...
...BRCA1 mutation status represent 0=healthy-brca1wt, 1=healthy-brca1mt, 2=breastcancer-brca1mt.
...BRCA1 siRNAs (siBRCA1 to deplete BRCA1). Immunoprecipitated genomic DNA was labelled with Cy3 and Input genomic DNA was...
...BRCA1 mutation status and clinical outcome using published microarray datasets and for correlation with pharmacological ...
...BRCA1 in DNA Damage Response’ was predicted to be the most significantly altered canonical pathway involved in intrinsic...
...BRCA1-deficient cells might extensively rewire the HR repair network and confer resistance to PARP inhibitor, partially ...
...BRCA1 genes were transfected in MCF-10A non-transformed breast cell line by lentiviral particles. Stable BRCA1 and PTEN ...
...BRCA1-deficient cells might extensively rewire the HR repair network and confer resistance to PARP inhibitor, partially ...
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