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Molecular Characterization and Subtyping of Breast Cancer Cell Lines Provide ...

样本量:29 物种:Homo sapiens, Homo sapiens 类型:RNA-seq of coding RNA 2024年12月3日

...BRCA2 in BC cell lines, which, therefore, share relevant characteristics with primary BC. Furthermore, we showed that th...

Treatment with onvansertib, a specific PLK1 inhibitor, overcomes olaparib res...

样本量:39 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA 2023年9月14日

...BRCA2 genes and this strong preclinical evidence prompted their clinical development in tumors with BRCA1/BRCA2 mutation...

Copy Number Variation in Brca2 (G25R) variant mouse tumors

样本量:32 物种:Mus musculus 类型:comparative genomic hybridization by ... 2016年7月27日

...Brca2 (G25R) and to see where common gains and losses occur within a Trp53 heterozygous genetic background Comparing mou...

Epigenetic reprogramming of Fallopian tube fimbriae in BRCA mutation carriers...

样本量:216 物种:Homo sapiens 类型:methylation profiling by array 2016年5月19日

...BRCA2 to cancer development the core components such as organ specificity (i.e. to breast and Fallopian Tube) are still ...

Large genomic alteration of 7q in two patients with multiple primary cancers,...

样本量:8 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2016年2月15日

...BRCA2 and TP53 genes and large genomic rearrangements mapped on chromosome 7q. Genomic rearrangements were assessed with...

Molecular Profiling of Metastatic Prostate Carcinoma Reveals Substantial Inte...

样本量:342 物种:Homo sapiens 类型:transcription profiling by array 2015年12月18日

...BRCA2 expression reduced prostate cancer growth. The limited molecular diversity across metastases may result from bottl...

RNA Profiles Reveals Familial Aggregation of Molecular Subtypes in non-BRCA1/...

样本量:506 物种:Homo sapiens 类型:transcription profiling by array 2015年8月1日

...BRCA2 (n = 22) or with no detectable germline mutation in BRCA1 or BRCA2 (n = 70) were included in the study. Serving as...

Concurrent DNA copy number alterations and mutations in genes related to main...

样本量:6 物种:Homo sapiens 类型:DNA-seq 2015年7月31日

...BRCA2 (p.Asn3124Ile), NCOR1 (p.Pro1570Glnfs*45), PALB2 (p.Ser500Pro) and TP53 (p.Arg306*). We demonstrated that gross SM...

Genotyping BRCA1 and BRCA2 in genomically unstable glandular tissue from brea...

样本量:6 物种:Homo sapiens 类型:DNA-seq 2015年7月31日

...BRCA2 (p.Asn3124Ile), NCOR1 (p.Pro1570Glnfs*45), PALB2 (p.Ser500Pro) and TP53 (p.Arg306*). We demonstrated that gross SM...

Concurrent DNA copy number alterations and mutations in genes related to main...

样本量:360 物种:Homo sapiens 类型:comparative genomic hybridization by ... 2015年7月30日

...BRCA2 (p.Asn3124Ile), NCOR1 (p.Pro1570Glnfs*45), PALB2 (p.Ser500Pro) and TP53 (p.Arg306*). We demonstrated that gross SM...

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